UA97469C2 - Гуманізована специфічна до cd37 зв'язувальна молекула імуноглобуліну - Google Patents

Гуманізована специфічна до cd37 зв'язувальна молекула імуноглобуліну Download PDF

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Publication number
UA97469C2
UA97469C2 UAA200802255A UAA200802255A UA97469C2 UA 97469 C2 UA97469 C2 UA 97469C2 UA A200802255 A UAA200802255 A UA A200802255A UA A200802255 A UAA200802255 A UA A200802255A UA 97469 C2 UA97469 C2 UA 97469C2
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Ukraine
Prior art keywords
specific
humanized
cells
immunoglobulin
binding
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UAA200802255A
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English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Лаура Сью Гросмейр
Марта Сюзан Хайден-Ледбеттер
Джеффрі А. Ледбеттер
Пітер Армстронг Томпсон
Санді Алєксандер Саймон
Уільям Бред
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Емерджент Продакт Дівелопмент Сіетл, Елелсі
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Publication of UA97469C2 publication Critical patent/UA97469C2/uk

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/565—Complementarity determining region [CDR]
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  • Proteomics, Peptides & Aminoacids (AREA)
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  • Biomedical Technology (AREA)
  • Hematology (AREA)
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  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Endocrinology (AREA)
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  • Pain & Pain Management (AREA)
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UAA200802255A 2005-07-25 2006-07-25 Гуманізована специфічна до cd37 зв'язувальна молекула імуноглобуліну UA97469C2 (uk)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US70249905P 2005-07-25 2005-07-25
US80059506P 2006-05-16 2006-05-16
PCT/US2006/029038 WO2007014278A2 (en) 2005-07-25 2006-07-25 B-cell reduction using cd37-specific and cd20-specific binding molecules

Publications (1)

Publication Number Publication Date
UA97469C2 true UA97469C2 (uk) 2012-02-27

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ID=37683960

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UAA200802255A UA97469C2 (uk) 2005-07-25 2006-07-25 Гуманізована специфічна до cd37 зв'язувальна молекула імуноглобуліну

Country Status (28)

Country Link
US (7) US10307481B2 (https=)
EP (4) EP2586798A3 (https=)
JP (3) JP5740076B2 (https=)
KR (1) KR101251157B1 (https=)
CN (2) CN105012953B (https=)
AU (1) AU2006272555B2 (https=)
BR (1) BRPI0614184A8 (https=)
CA (1) CA2616395C (https=)
CO (1) CO6160337A2 (https=)
CR (1) CR9761A (https=)
DK (2) DK2298815T3 (https=)
EC (1) ECSP088133A (https=)
ES (2) ES2539250T3 (https=)
HR (2) HRP20140338T1 (https=)
HU (1) HUE026303T2 (https=)
IL (2) IL188345A (https=)
NI (1) NI200800032A (https=)
NO (1) NO20080217L (https=)
NZ (3) NZ594275A (https=)
PL (2) PL1912675T3 (https=)
PT (2) PT2298815E (https=)
RS (2) RS53318B (https=)
RU (1) RU2423381C2 (https=)
SG (2) SG155912A1 (https=)
SI (2) SI1912675T1 (https=)
UA (1) UA97469C2 (https=)
WO (1) WO2007014278A2 (https=)
ZA (1) ZA200800692B (https=)

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US20030133939A1 (en) 2001-01-17 2003-07-17 Genecraft, Inc. Binding domain-immunoglobulin fusion proteins
US7754208B2 (en) 2001-01-17 2010-07-13 Trubion Pharmaceuticals, Inc. Binding domain-immunoglobulin fusion proteins
US7829084B2 (en) * 2001-01-17 2010-11-09 Trubion Pharmaceuticals, Inc. Binding constructs and methods for use thereof
US8563592B2 (en) 2001-11-01 2013-10-22 Spectrum Pharmaceuticals, Inc. Bladder cancer treatment and methods
AU2002350115A1 (en) 2001-11-01 2003-05-12 Spectrum Pharmaceuticals, Inc. Medical compositions for intravesical treatment of bladder cancer
RU2423381C2 (ru) * 2005-07-25 2011-07-10 Трабьон Фармасьютикалз, Инк. Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул
RU2396953C2 (ru) * 2006-02-09 2010-08-20 Спектрум Фармасьютикалз, Инк. Лечение рака мочевого пузыря с использованием ео9 и пропиленгликоля
CA2646329C (en) 2006-03-20 2018-07-03 The Regents Of The University Of California Engineered anti-prostate stem cell antigen (psca) antibodies for cancer targeting
NZ573646A (en) 2006-06-12 2012-04-27 Wyeth Llc Single-chain multivalent binding proteins with effector function
JP2010507394A (ja) * 2006-10-24 2010-03-11 トルービオン ファーマスーティカルズ インコーポレイテッド 改良免疫糖タンパク質のための物質および方法
US7846434B2 (en) * 2006-10-24 2010-12-07 Trubion Pharmaceuticals, Inc. Materials and methods for improved immunoglycoproteins
JP2010531137A (ja) * 2007-06-12 2010-09-24 ワイス・エルエルシー 抗ｃｄ２０治療用組成物および方法
PE20140196A1 (es) 2007-08-09 2014-03-19 Boehringer Ingelheim Int Anticuerpos anti-cd37
WO2009032949A2 (en) 2007-09-04 2009-03-12 The Regents Of The University Of California High affinity anti-prostate stem cell antigen (psca) antibodies for cancer targeting and detection
MX2010003329A (es) 2007-09-26 2010-04-27 Chugai Pharmaceutical Co Ltd Anticuerpo anti-receptor de il-6.
ES2595638T3 (es) 2007-09-26 2017-01-02 Chugai Seiyaku Kabushiki Kaisha Método para modificar el punto isoeléctrico de un anticuerpo mediante la sustitución de aminoácidos en una CDR
CA2700410C (en) * 2007-10-03 2020-10-06 Cornell University Treatment of proliferative disorders using antibodies to psma
WO2009086072A2 (en) 2007-12-21 2009-07-09 Genentech, Inc. Therapy of rituximab-refractory rheumatoid arthritis patients
KR102057826B1 (ko) 2008-04-11 2019-12-20 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복 결합하는 항원 결합 분자
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