UA88485C2 - 2,6-substituted-4-monosubstituted amino-pyrimidines as prostaglandin d2 receptor antagonists - Google Patents

2,6-substituted-4-monosubstituted amino-pyrimidines as prostaglandin d2 receptor antagonists

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Publication number
UA88485C2
UA88485C2 UAA200705281A UAA200705281A UA88485C2 UA 88485 C2 UA88485 C2 UA 88485C2 UA A200705281 A UAA200705281 A UA A200705281A UA A200705281 A UAA200705281 A UA A200705281A UA 88485 C2 UA88485 C2 UA 88485C2
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UA
Ukraine
Prior art keywords
formula
accompanied
diseases
itch
urticaria
Prior art date
Application number
UAA200705281A
Other languages
English (en)
Russian (ru)
Inventor
Сунгтаек Лим
Кейт Джон Харрис
Девид Стефани
Чарльз Дж. Гарднер
Бин ЦАО
Рей Боффи
Тимоти А. ГИЛЛЕСПИ
Жуаси К. АГИАР
Хейзел Дж. Хант
Эльза А. Дешо
Original Assignee
Авентис Фармасьютикалз Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Фармасьютикалз Инк. filed Critical Авентис Фармасьютикалз Инк.
Publication of UA88485C2 publication Critical patent/UA88485C2/ru

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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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  • Chemical & Material Sciences (AREA)
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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
UAA200705281A 2004-10-15 2005-10-14 2,6-substituted-4-monosubstituted amino-pyrimidines as prostaglandin d2 receptor antagonists UA88485C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US61927204P 2004-10-15 2004-10-15

Publications (1)

Publication Number Publication Date
UA88485C2 true UA88485C2 (en) 2009-10-26

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US (2) US8193183B2 (https=)
EP (1) EP1891019B1 (https=)
JP (1) JP4970274B2 (https=)
KR (1) KR101280268B1 (https=)
CN (1) CN101039920B (https=)
AR (1) AR053770A1 (https=)
AU (1) AU2005295502B2 (https=)
BR (1) BRPI0516482A (https=)
CA (1) CA2583742C (https=)
CR (1) CR9003A (https=)
DK (1) DK1891019T3 (https=)
EC (1) ECSP077398A (https=)
ES (1) ES2392091T3 (https=)
GT (1) GT200500284A (https=)
HN (1) HN2005000795A (https=)
IL (1) IL182090A (https=)
MA (1) MA29071B1 (https=)
MX (1) MX2007003155A (https=)
MY (2) MY157036A (https=)
NO (1) NO339772B1 (https=)
NZ (1) NZ553919A (https=)
PA (1) PA8649801A1 (https=)
PE (1) PE20060936A1 (https=)
PL (1) PL1891019T3 (https=)
PT (1) PT1891019E (https=)
RU (1) RU2417990C2 (https=)
SG (1) SG156653A1 (https=)
SI (1) SI1891019T1 (https=)
SV (1) SV2006002272A (https=)
TN (1) TNSN07098A1 (https=)
TW (1) TWI372751B (https=)
UA (1) UA88485C2 (https=)
UY (1) UY29167A1 (https=)
WO (1) WO2006044732A2 (https=)
ZA (1) ZA200702209B (https=)

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WO2008039882A1 (en) * 2006-09-30 2008-04-03 Sanofi-Aventis U.S. Llc A combination of niacin and a prostaglandin d2 receptor antagonist
DK2142516T3 (da) * 2007-03-30 2013-04-15 Sanofi Sa Pyrimidinhydrazidforbindelser i ders egenskab af pgds-inhibitorer
BRPI0810719A8 (pt) * 2007-04-30 2016-03-08 Abbott Lab Inibidores da enzima diacilglicerol o-acetiltansferase tipo 1
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WO2009006086A2 (en) 2007-06-29 2009-01-08 Sanofi-Aventis A new process for preparing 2-(3-{6-[2-(2,4-dichlorophenyl)-ethylamino]-2-methoxypyrimidin-4-yl}-phenyl)- 2-methylpropionic acid
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CN101902912A (zh) 2007-11-06 2010-12-01 纳幕尔杜邦公司 杀真菌杂环胺
AU2008343813B2 (en) 2007-12-19 2012-04-12 Amgen Inc. Inhibitors of PI3 kinase
JP2011507909A (ja) 2007-12-20 2011-03-10 エンビボ ファーマシューティカルズ インコーポレイテッド 四置換ベンゼン
CA2714743C (en) 2008-02-19 2017-01-17 Janssen Pharmaceutica N.V. Aryl-hydroxyethylamino-pyrimidines and triazines as modulators of fatty acid amide hydrolase
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