UA39879C2 - Атовакон у формі частинок, фармацевтична композиція, що містить частинки атовакону та спосіб її одержання, спосіб одержання мікропсевдозріджених частинок атовакону - Google Patents
Атовакон у формі частинок, фармацевтична композиція, що містить частинки атовакону та спосіб її одержання, спосіб одержання мікропсевдозріджених частинок атоваконуInfo
- Publication number
- UA39879C2 UA39879C2 UA95062971A UA95062971A UA39879C2 UA 39879 C2 UA39879 C2 UA 39879C2 UA 95062971 A UA95062971 A UA 95062971A UA 95062971 A UA95062971 A UA 95062971A UA 39879 C2 UA39879 C2 UA 39879C2
- Authority
- UA
- Ukraine
- Prior art keywords
- alcohol
- preparation
- atovacon
- particles
- purified
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 238000002360 preparation method Methods 0.000 title abstract 3
- 239000002245 particle Substances 0.000 title 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 12
- 235000019441 ethanol Nutrition 0.000 abstract 7
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 6
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 abstract 6
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 150000001299 aldehydes Chemical class 0.000 abstract 2
- 238000005194 fractionation Methods 0.000 abstract 2
- 239000001760 fusel oil Substances 0.000 abstract 2
- 239000012535 impurity Substances 0.000 abstract 2
- 235000013334 alcoholic beverage Nutrition 0.000 abstract 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 239000012153 distilled water Substances 0.000 abstract 1
- IDGUHHHQCWSQLU-UHFFFAOYSA-N ethanol;hydrate Chemical compound O.CCO IDGUHHHQCWSQLU-UHFFFAOYSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Fertilizers (AREA)
Abstract
Спосіб приготування розчину водно-етанольного типового. Винахід відноситься до харчової промисловості, зокрема до лікеро-горілчаної галузі. Спосіб передбачає очистку спирту етилового та змішування його з водою дистильованою і реактивами. Спирт етиловий очищають до вмісту домішок, в перерахунку на безводний спирт: альдегідів 0,1-1,0 мг/дм3, сивушного масла 0,1-2,0 мг/дм3, метилового спирту 0,001-0,01 об.%. Спирт етиловий очищають від сивушного масла хімічним способом при дії порошку алюмінію і їдкого калію кількістю по 8-10 г/дм3 кожного протягом 50-80 хвилин при температурі 70-90 С з подальшим фракціонуванням спирту. Далі спирт етиловий очищають від альдегідів та метилового спирту хімічним способом при дії оцтовокислого свинцю кількістю 2,5-3 г/дм3 і їдкого калію кількістю 4-5 г/дм3 протягом 10-12 годин при температурі 15-25 С з подальшим фракціонуванням спирту. Технічним результатом винаходу є зниження до оптимальної допустимих концентрацій шкідливих домішок в вихідному спирті.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929226905A GB9226905D0 (en) | 1992-12-24 | 1992-12-24 | Pharmaceutical preparation |
| PCT/GB1993/002646 WO1994014426A1 (en) | 1992-12-24 | 1993-12-23 | Atovaquone pharmaceutical compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA39879C2 true UA39879C2 (uk) | 2001-07-16 |
Family
ID=10727175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA95062971A UA39879C2 (uk) | 1992-12-24 | 1993-12-23 | Атовакон у формі частинок, фармацевтична композиція, що містить частинки атовакону та спосіб її одержання, спосіб одержання мікропсевдозріджених частинок атовакону |
Country Status (36)
| Country | Link |
|---|---|
| US (2) | US6018080A (uk) |
| EP (1) | EP0675711B1 (uk) |
| JP (1) | JP3461353B2 (uk) |
| KR (1) | KR0175193B1 (uk) |
| CN (1) | CN1076194C (uk) |
| AT (1) | ATE169215T1 (uk) |
| AU (2) | AU675102B2 (uk) |
| BG (1) | BG61932B1 (uk) |
| BR (1) | BR9307719A (uk) |
| CA (1) | CA2152615C (uk) |
| CZ (1) | CZ289701B6 (uk) |
| DE (1) | DE69320208T2 (uk) |
| DK (1) | DK0675711T3 (uk) |
| ES (1) | ES2122223T3 (uk) |
| FI (1) | FI114007B (uk) |
| GB (1) | GB9226905D0 (uk) |
| GE (1) | GEP19991515B (uk) |
| HK (1) | HK1004086A1 (uk) |
| HR (1) | HRP931516B1 (uk) |
| HU (1) | HU220215B (uk) |
| IL (1) | IL108154A (uk) |
| MY (1) | MY109990A (uk) |
| NO (1) | NO316745B1 (uk) |
| NZ (1) | NZ258995A (uk) |
| PL (1) | PL175374B1 (uk) |
| RO (1) | RO119686B1 (uk) |
| RU (1) | RU2127585C1 (uk) |
| SA (1) | SA94140644B1 (uk) |
| SG (1) | SG43901A1 (uk) |
| SI (1) | SI9300678A (uk) |
| SK (1) | SK281924B6 (uk) |
| TW (2) | TW514531B (uk) |
| UA (1) | UA39879C2 (uk) |
| WO (1) | WO1994014426A1 (uk) |
| YU (1) | YU48919B (uk) |
| ZA (1) | ZA939673B (uk) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9224739D0 (en) * | 1992-11-26 | 1993-01-13 | Wellcome Found | Medicaments |
| GB9226905D0 (en) * | 1992-12-24 | 1993-02-17 | Wellcome Found | Pharmaceutical preparation |
| AU3705695A (en) * | 1994-10-26 | 1996-05-23 | Wellcome Foundation Limited, The | Pharmaceutical composition comprising atovaquone |
| DE4440337A1 (de) * | 1994-11-11 | 1996-05-15 | Dds Drug Delivery Services Ges | Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit |
| GB9424013D0 (en) * | 1994-11-29 | 1995-01-18 | Wellcome Found | Medicaments |
| ATE265846T1 (de) * | 1998-02-25 | 2004-05-15 | Abbott Lab | Butorphanol enthaltende formulierungen mit verzögerter freisetzung |
| US6503949B1 (en) | 1999-05-17 | 2003-01-07 | Noro Nordisk A/S | Glucagon antagonists/inverse agonists |
| US6562807B2 (en) | 2000-06-23 | 2003-05-13 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| US6821960B2 (en) | 2000-11-17 | 2004-11-23 | Noyo Nordisk Pharmaceuticals, Inc. | Glucagon antagonists/inverse agonists |
| WO2002040445A1 (en) | 2000-11-17 | 2002-05-23 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| US6706744B2 (en) | 2000-11-17 | 2004-03-16 | Novo Nordisk A/S | Glucagon antagonists/inverse agonists |
| US6762318B2 (en) | 2001-12-03 | 2004-07-13 | Novo Nordisk A/S | Glucagon antagonists |
| US6881746B2 (en) | 2001-12-03 | 2005-04-19 | Novo Nordick A/S | Glucagon antagonists/inverse agonists |
| US7183518B2 (en) * | 2004-09-24 | 2007-02-27 | Michael Near | System of food storage preparation and delivery in finished cooked state |
| DE102005011786A1 (de) * | 2005-03-11 | 2006-09-14 | Pharmasol Gmbh | Verfahren zur Herstellung ultrafeiner Submicron-Suspensionen |
| DE502006005846D1 (de) * | 2005-04-13 | 2010-02-25 | Abbott Gmbh & Co Kg | Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung |
| US20080241254A1 (en) * | 2007-01-02 | 2008-10-02 | Suryakant Navale | Pharmaceutical composition comprising atovaquone particles |
| DE102007001473A1 (de) | 2007-01-08 | 2008-07-10 | Andreas Lemke | Verfahren zur Herstellung und Anwendung von Mikro- und/oder Nanosuspensionen durch aufbauende Mikronisierung in Gegenwart von Trockeneis und hohem Druck |
| WO2009007991A2 (en) * | 2007-04-19 | 2009-01-15 | Ipca Laboratories Limited | A new process for preparation of atovaquone and novel intermediates thereof |
| AU2009273747A1 (en) * | 2008-07-25 | 2010-01-28 | Alphapharm Pty Ltd | Atovaquone with a particle size diameter range (D90) of greater than 3 um to about 10 um |
| US20100099776A1 (en) * | 2008-10-20 | 2010-04-22 | Ranbaxy Laboratories Limited | Oily suspension of atovaquone |
| EP2467358B1 (en) | 2009-08-20 | 2014-07-23 | IPCA Laboratories Limited | Novel complex for treatment and/or prophylaxis of parasitic infections |
| CA2780292A1 (en) | 2009-11-10 | 2011-05-19 | Celgene Corporation | Nanosus pens ion of a poorly soluble drug made by microfluidization process |
| WO2011151418A2 (en) | 2010-06-02 | 2011-12-08 | Abbott Gmbh & Co. Kg | Nanosusupension formulation comprising a polydimethylsiloxane hydrophobic phase |
| WO2014100403A1 (en) | 2012-12-19 | 2014-06-26 | Kashiv Pharma, Llc | Supersaturated stabilized nanoparticles for poorly soluble drugs |
| WO2015071841A1 (en) | 2013-11-12 | 2015-05-21 | Druggability Technologies Holdings Limited | Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them |
| CN109640948B (zh) * | 2016-06-16 | 2023-05-02 | 利物浦大学 | 化学组合物 |
| US20220265566A1 (en) * | 2018-10-18 | 2022-08-25 | Tulex Pharmaceuticals Inc. | Atovaquone nanoparticulate compositions |
Family Cites Families (39)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2533648A (en) * | 1949-03-05 | 1950-12-12 | Joseph H Warburg | Circular saw making |
| NL6411993A (uk) * | 1963-10-18 | 1965-04-20 | ||
| US3347830A (en) * | 1964-07-30 | 1967-10-17 | Grace W R & Co | Process of polymerizing formaldehyde |
| GB1141735A (en) * | 1966-11-23 | 1969-01-29 | Pfizer & Co C | Pharmaceutical anti-tumor composition |
| US3655699A (en) * | 1970-03-02 | 1972-04-11 | Pfizer | Analogues of lapachol as antitumor agents |
| US4107288A (en) | 1974-09-18 | 1978-08-15 | Pharmaceutical Society Of Victoria | Injectable compositions, nanoparticles useful therein, and process of manufacturing same |
| DE2601458A1 (de) * | 1975-01-20 | 1976-07-22 | Ciba Geigy Ag | Loesliche, von phenylindandiaminen abgeleitete polyamide |
| EP0002228B1 (en) * | 1977-11-22 | 1984-02-29 | The Wellcome Foundation Limited | Hydroxy naphthoquinone derivatives, their preparations for treating and preventing theileriosis in cattle and sheep, processes for their synthesis; naphthoquinone derivatives |
| US4485117A (en) | 1981-10-16 | 1984-11-27 | Hudson Alan T | Antiprotozoal compounds |
| US4485116A (en) * | 1981-10-16 | 1984-11-27 | Hudson Alan T | Antiprotozoal compounds |
| DE3141691A1 (de) * | 1981-10-21 | 1983-05-19 | Hoechst Ag, 6230 Frankfurt | Plasmid pac 1, verfahren zu seiner gewinnung und seine verwendung |
| GB8310140D0 (en) * | 1983-04-14 | 1983-05-18 | Wellcome Found | Antiprotozoal agents |
| US5053432A (en) * | 1983-04-14 | 1991-10-01 | Burroughs Wellcome Co. | Naphthoquinone derivatives |
| GB8310141D0 (en) * | 1983-04-14 | 1983-05-18 | Wellcome Found | Naphthoquinone derivatives |
| US5175319A (en) | 1983-04-14 | 1992-12-29 | Burroughs Wellcome Co. | Naphthoquinone derivatives |
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| PL276385A1 (en) * | 1987-01-30 | 1989-07-24 | Exxon Chemical Patents Inc | Method for polymerization of olefines,diolefins and acetylene unsaturated compounds |
| IL85097A (en) * | 1987-01-30 | 1992-02-16 | Exxon Chemical Patents Inc | Catalysts based on derivatives of a bis(cyclopentadienyl)group ivb metal compound,their preparation and their use in polymerization processes |
| US4783389A (en) * | 1987-03-27 | 1988-11-08 | E. I. Du Pont De Nemours And Company | Process for preparation of liquid electrostatic developers |
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| GB8819477D0 (en) * | 1988-08-16 | 1988-09-21 | Wellcome Found | Medicaments |
| US5225184A (en) * | 1988-08-16 | 1993-07-06 | Burroughs Wellcome Co. | Medicaments |
| US5206268A (en) * | 1988-08-16 | 1993-04-27 | Burroughs Wellcome Co. | Medicaments |
| DE68914930T2 (de) * | 1988-08-16 | 1994-08-18 | Wellcome Found | Naphtochinone zur Behandlung und Prophylaxe von Pneumocystis carinii-Infektionen. |
| KR930002411B1 (ko) * | 1988-09-14 | 1993-03-30 | 미쓰이세끼유 가가꾸고오교오 가부시끼가이샤 | 벤젠불용성 유기알루미늄 옥시화합물 및 그 제조방법 |
| GB8921516D0 (en) * | 1989-09-22 | 1989-11-08 | Wellcome Found | Medicaments |
| ATE137770T1 (de) * | 1989-10-10 | 1996-05-15 | Fina Technology | Metallocenkatalysator mit lewissäure und alkylaluminium |
| GB8923254D0 (en) * | 1989-10-16 | 1989-12-06 | Wellcome Found | Medicaments |
| DE69026679T3 (de) * | 1989-10-30 | 2005-10-06 | Fina Technology, Inc., Houston | Addition von Alkylaluminium zum Verbessern eines Metallocenkatalysators |
| US5387568A (en) * | 1989-10-30 | 1995-02-07 | Fina Technology, Inc. | Preparation of metallocene catalysts for polymerization of olefins |
| DE3942363A1 (de) * | 1989-12-21 | 1991-06-27 | Hoechst Ag | Verfahren zur herstellung einer polypropylen-formmasse |
| JP2545006B2 (ja) * | 1990-07-03 | 1996-10-16 | ザ ダウ ケミカル カンパニー | 付加重合触媒 |
| JP3076619B2 (ja) | 1991-05-14 | 2000-08-14 | 三井化学株式会社 | ブロック共重合体の製造方法 |
| GB9226905D0 (en) * | 1992-12-24 | 1993-02-17 | Wellcome Found | Pharmaceutical preparation |
| US5510118A (en) | 1995-02-14 | 1996-04-23 | Nanosystems Llc | Process for preparing therapeutic compositions containing nanoparticles |
| US5766522A (en) * | 1996-07-19 | 1998-06-16 | Morton International, Inc. | Continuous processing of powder coating compositions |
| US5976578A (en) * | 1996-10-10 | 1999-11-02 | Mcneil-Ppc, Inc. | Liquid antacid compositions |
| US5914135A (en) * | 1997-04-16 | 1999-06-22 | Mcneil-Ppc, Inc. | Liquid antacid compositions |
-
1992
- 1992-12-24 GB GB929226905A patent/GB9226905D0/en active Pending
-
1993
- 1993-12-20 GE GEAP19931692A patent/GEP19991515B/en unknown
- 1993-12-22 YU YU80893A patent/YU48919B/sh unknown
- 1993-12-23 PL PL93309629A patent/PL175374B1/pl unknown
- 1993-12-23 CN CN93121376A patent/CN1076194C/zh not_active Expired - Fee Related
- 1993-12-23 BR BR9307719-0A patent/BR9307719A/pt not_active Application Discontinuation
- 1993-12-23 DE DE69320208T patent/DE69320208T2/de not_active Expired - Lifetime
- 1993-12-23 SG SG1996004546A patent/SG43901A1/en unknown
- 1993-12-23 RU RU95122758A patent/RU2127585C1/ru active
- 1993-12-23 CZ CZ19951451A patent/CZ289701B6/cs not_active IP Right Cessation
- 1993-12-23 CA CA002152615A patent/CA2152615C/en not_active Expired - Lifetime
- 1993-12-23 JP JP51496894A patent/JP3461353B2/ja not_active Expired - Lifetime
- 1993-12-23 SI SI9300678A patent/SI9300678A/sl unknown
- 1993-12-23 KR KR1019950702217A patent/KR0175193B1/ko not_active IP Right Cessation
- 1993-12-23 ZA ZA939673A patent/ZA939673B/xx unknown
- 1993-12-23 AU AU57105/94A patent/AU675102B2/en not_active Expired
- 1993-12-23 EP EP94902952A patent/EP0675711B1/en not_active Expired - Lifetime
- 1993-12-23 AT AT94902952T patent/ATE169215T1/de active
- 1993-12-23 TW TW088101847A patent/TW514531B/zh not_active IP Right Cessation
- 1993-12-23 HU HU9501812A patent/HU220215B/hu unknown
- 1993-12-23 ES ES94902952T patent/ES2122223T3/es not_active Expired - Lifetime
- 1993-12-23 TW TW082110927A patent/TW443935B/zh not_active IP Right Cessation
- 1993-12-23 HR HR9226905.9A patent/HRP931516B1/xx not_active IP Right Cessation
- 1993-12-23 DK DK94902952T patent/DK0675711T3/da active
- 1993-12-23 UA UA95062971A patent/UA39879C2/uk unknown
- 1993-12-23 WO PCT/GB1993/002646 patent/WO1994014426A1/en active IP Right Grant
- 1993-12-23 RO RO95-01191A patent/RO119686B1/ro unknown
- 1993-12-23 SK SK828-95A patent/SK281924B6/sk not_active IP Right Cessation
- 1993-12-23 NZ NZ258995A patent/NZ258995A/en not_active IP Right Cessation
- 1993-12-23 IL IL10815493A patent/IL108154A/xx not_active IP Right Cessation
- 1993-12-23 MY MYPI93002823A patent/MY109990A/en unknown
-
1994
- 1994-04-03 SA SA94140644A patent/SA94140644B1/ar unknown
-
1995
- 1995-06-15 BG BG99723A patent/BG61932B1/bg unknown
- 1995-06-22 FI FI953139A patent/FI114007B/fi not_active IP Right Cessation
- 1995-06-22 NO NO19952522A patent/NO316745B1/no not_active IP Right Cessation
-
1997
- 1997-03-14 AU AU16279/97A patent/AU696662B2/en not_active Ceased
- 1997-11-19 US US08/974,248 patent/US6018080A/en not_active Expired - Lifetime
-
1998
- 1998-04-20 HK HK98103299A patent/HK1004086A1/xx not_active IP Right Cessation
-
1999
- 1999-10-04 US US09/411,381 patent/US6649659B1/en not_active Expired - Lifetime
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