ES2122223T3 - Composiciones farmaceuticas de atovaquona. - Google Patents

Composiciones farmaceuticas de atovaquona.

Info

Publication number
ES2122223T3
ES2122223T3 ES94902952T ES94902952T ES2122223T3 ES 2122223 T3 ES2122223 T3 ES 2122223T3 ES 94902952 T ES94902952 T ES 94902952T ES 94902952 T ES94902952 T ES 94902952T ES 2122223 T3 ES2122223 T3 ES 2122223T3
Authority
ES
Spain
Prior art keywords
atovaquona
pharmaceutical compositions
microfluidized
particulates
therapies
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94902952T
Other languages
English (en)
Inventor
Alan Roy Dearn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Application granted granted Critical
Publication of ES2122223T3 publication Critical patent/ES2122223T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fertilizers (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

LA INVENCION SE REFIERE A PARTICULAS MICROFLUIDIZADAS DE AUTOVACUNAS Y A UN METODO PARA PREPARARLAS. MAS PARTICULARMENTE, LA INVENCION SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE CONTIENE PARTICULAS MICROFLUIDIZADAS DE AUTOVACUNA QUE TIENE UNA BIOACTIVIDAD MEJORADA Y SU USO EN TERAPIAS.
ES94902952T 1992-12-24 1993-12-23 Composiciones farmaceuticas de atovaquona. Expired - Lifetime ES2122223T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929226905A GB9226905D0 (en) 1992-12-24 1992-12-24 Pharmaceutical preparation

Publications (1)

Publication Number Publication Date
ES2122223T3 true ES2122223T3 (es) 1998-12-16

Family

ID=10727175

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94902952T Expired - Lifetime ES2122223T3 (es) 1992-12-24 1993-12-23 Composiciones farmaceuticas de atovaquona.

Country Status (36)

Country Link
US (2) US6018080A (es)
EP (1) EP0675711B1 (es)
JP (1) JP3461353B2 (es)
KR (1) KR0175193B1 (es)
CN (1) CN1076194C (es)
AT (1) ATE169215T1 (es)
AU (2) AU675102B2 (es)
BG (1) BG61932B1 (es)
BR (1) BR9307719A (es)
CA (1) CA2152615C (es)
CZ (1) CZ289701B6 (es)
DE (1) DE69320208T2 (es)
DK (1) DK0675711T3 (es)
ES (1) ES2122223T3 (es)
FI (1) FI114007B (es)
GB (1) GB9226905D0 (es)
GE (1) GEP19991515B (es)
HK (1) HK1004086A1 (es)
HR (1) HRP931516B1 (es)
HU (1) HU220215B (es)
IL (1) IL108154A (es)
MY (1) MY109990A (es)
NO (1) NO316745B1 (es)
NZ (1) NZ258995A (es)
PL (1) PL175374B1 (es)
RO (1) RO119686B1 (es)
RU (1) RU2127585C1 (es)
SA (1) SA94140644B1 (es)
SG (1) SG43901A1 (es)
SI (1) SI9300678A (es)
SK (1) SK281924B6 (es)
TW (2) TW514531B (es)
UA (1) UA39879C2 (es)
WO (1) WO1994014426A1 (es)
YU (1) YU48919B (es)
ZA (1) ZA939673B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9224739D0 (en) * 1992-11-26 1993-01-13 Wellcome Found Medicaments
GB9226905D0 (en) * 1992-12-24 1993-02-17 Wellcome Found Pharmaceutical preparation
AU3705695A (en) * 1994-10-26 1996-05-23 Wellcome Foundation Limited, The Pharmaceutical composition comprising atovaquone
DE4440337A1 (de) * 1994-11-11 1996-05-15 Dds Drug Delivery Services Ges Pharmazeutische Nanosuspensionen zur Arzneistoffapplikation als Systeme mit erhöhter Sättigungslöslichkeit und Lösungsgeschwindigkeit
GB9424013D0 (en) * 1994-11-29 1995-01-18 Wellcome Found Medicaments
JP2002504505A (ja) * 1998-02-25 2002-02-12 アボット・ラボラトリーズ ブトルファノール持続放出性製剤
US6503949B1 (en) 1999-05-17 2003-01-07 Noro Nordisk A/S Glucagon antagonists/inverse agonists
US6562807B2 (en) 2000-06-23 2003-05-13 Novo Nordisk A/S Glucagon antagonists/inverse agonists
US6821960B2 (en) 2000-11-17 2004-11-23 Noyo Nordisk Pharmaceuticals, Inc. Glucagon antagonists/inverse agonists
AU2002223500A1 (en) 2000-11-17 2002-05-27 Novo-Nordisk A/S Glucagon antagonists/inverse agonists
US6706744B2 (en) 2000-11-17 2004-03-16 Novo Nordisk A/S Glucagon antagonists/inverse agonists
US6881746B2 (en) 2001-12-03 2005-04-19 Novo Nordick A/S Glucagon antagonists/inverse agonists
US6762318B2 (en) 2001-12-03 2004-07-13 Novo Nordisk A/S Glucagon antagonists
US7183518B2 (en) * 2004-09-24 2007-02-27 Michael Near System of food storage preparation and delivery in finished cooked state
DE102005011786A1 (de) * 2005-03-11 2006-09-14 Pharmasol Gmbh Verfahren zur Herstellung ultrafeiner Submicron-Suspensionen
WO2006108637A2 (de) * 2005-04-13 2006-10-19 Abbott Gmbh & Co.Kg Verfahren zur schonenden herstellung hochfeiner partikelsuspensionen und hochfeiner partikel sowie deren verwendung
US20080241254A1 (en) * 2007-01-02 2008-10-02 Suryakant Navale Pharmaceutical composition comprising atovaquone particles
DE102007001473A1 (de) 2007-01-08 2008-07-10 Andreas Lemke Verfahren zur Herstellung und Anwendung von Mikro- und/oder Nanosuspensionen durch aufbauende Mikronisierung in Gegenwart von Trockeneis und hohem Druck
WO2009007991A2 (en) * 2007-04-19 2009-01-15 Ipca Laboratories Limited A new process for preparation of atovaquone and novel intermediates thereof
US20110206770A1 (en) * 2008-07-25 2011-08-25 Alphapharm Pty. Ltd. Atovaquone with a particle size diameter range (d90) of greater than 3 microns to about 10 microns
US20100099776A1 (en) * 2008-10-20 2010-04-22 Ranbaxy Laboratories Limited Oily suspension of atovaquone
US8987234B2 (en) 2009-08-20 2015-03-24 Ipca Laboratories Ltd. Complex for treatment and/or prophylaxis of parasitic infections
ES2727733T3 (es) 2009-11-10 2019-10-18 Celgene Corp Nanosuspensión de un fármaco poco soluble preparada por el proceso de microfluidización
WO2011151418A2 (en) 2010-06-02 2011-12-08 Abbott Gmbh & Co. Kg Nanosusupension formulation comprising a polydimethylsiloxane hydrophobic phase
CA2895529C (en) 2012-12-19 2018-08-21 Kashiv Pharma, Llc Supersaturated stabilized nanoparticles for poorly soluble drugs
WO2015071841A1 (en) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes of dabigatran and its derivatives, process for the preparation thereof and pharmaceutical compositions containing them
US20190321310A1 (en) * 2016-06-16 2019-10-24 The University Of Liverpool Chemical composition
US20220265566A1 (en) * 2018-10-18 2022-08-25 Tulex Pharmaceuticals Inc. Atovaquone nanoparticulate compositions

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US3347830A (en) * 1964-07-30 1967-10-17 Grace W R & Co Process of polymerizing formaldehyde
GB1141735A (en) * 1966-11-23 1969-01-29 Pfizer & Co C Pharmaceutical anti-tumor composition
US3655699A (en) * 1970-03-02 1972-04-11 Pfizer Analogues of lapachol as antitumor agents
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
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Also Published As

Publication number Publication date
BG99723A (bg) 1996-01-31
NO316745B1 (no) 2004-04-26
UA39879C2 (uk) 2001-07-16
TW514531B (en) 2002-12-21
SK281924B6 (sk) 2001-09-11
HRP931516A2 (en) 1995-10-31
AU696662B2 (en) 1998-09-17
FI114007B (fi) 2004-07-30
RU2127585C1 (ru) 1999-03-20
JPH08504805A (ja) 1996-05-28
SG43901A1 (en) 1997-11-14
PL309629A1 (en) 1995-10-30
US6018080A (en) 2000-01-25
SA94140644B1 (ar) 2005-06-14
US6649659B1 (en) 2003-11-18
CZ145195A3 (en) 1995-10-18
NO952522D0 (no) 1995-06-22
NO952522L (no) 1995-06-22
SK82895A3 (en) 1995-11-08
DE69320208T2 (de) 1999-01-21
CN1103290A (zh) 1995-06-07
ZA939673B (en) 1995-06-23
HRP931516B1 (en) 1999-04-30
GEP19991515B (en) 1999-03-05
FI953139A (fi) 1995-06-22
TW443935B (en) 2001-07-01
CA2152615A1 (en) 1994-07-07
AU1627997A (en) 1997-05-22
DK0675711T3 (da) 1999-05-03
DE69320208D1 (de) 1998-09-10
IL108154A0 (en) 1994-04-12
FI953139A0 (fi) 1995-06-22
YU48919B (sh) 2002-11-15
PL175374B1 (pl) 1998-12-31
ATE169215T1 (de) 1998-08-15
YU80893A (sh) 1997-03-07
HK1004086A1 (en) 1998-11-13
HU220215B (hu) 2001-11-28
HU9501812D0 (en) 1995-08-28
KR0175193B1 (ko) 1999-02-01
HUT71528A (en) 1995-12-28
SI9300678A (en) 1994-09-30
RO119686B1 (ro) 2005-02-28
CN1076194C (zh) 2001-12-19
IL108154A (en) 2000-02-17
BR9307719A (pt) 1999-08-31
GB9226905D0 (en) 1993-02-17
BG61932B1 (bg) 1998-10-30
AU675102B2 (en) 1997-01-23
JP3461353B2 (ja) 2003-10-27
KR950703942A (ko) 1995-11-17
CZ289701B6 (cs) 2002-03-13
MY109990A (en) 1997-10-31
AU5710594A (en) 1994-07-19
CA2152615C (en) 2001-10-16
EP0675711B1 (en) 1998-08-05
EP0675711A1 (en) 1995-10-11
NZ258995A (en) 1997-01-29
WO1994014426A1 (en) 1994-07-07

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