DK0391185T3 - 1,8-Naphthyridiner - Google Patents

1,8-Naphthyridiner

Info

Publication number
DK0391185T3
DK0391185T3 DK90105652.3T DK90105652T DK0391185T3 DK 0391185 T3 DK0391185 T3 DK 0391185T3 DK 90105652 T DK90105652 T DK 90105652T DK 0391185 T3 DK0391185 T3 DK 0391185T3
Authority
DK
Denmark
Prior art keywords
naphthyridines
substituted
appropriate
cyclisation
medicaments
Prior art date
Application number
DK90105652.3T
Other languages
English (en)
Inventor
Delf Dr Schmidt
Hilmar Dr Bischoff
Walter Dr Huebsch
Peter Dr Fey
Thomas Dr Philipps
Rolf Dr Angerbauer
Dieter Dr Dr Petzinna
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0391185T3 publication Critical patent/DK0391185T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK90105652.3T 1989-04-06 1990-03-24 1,8-Naphthyridiner DK0391185T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3911064A DE3911064A1 (de) 1989-04-06 1989-04-06 Substituierte 1,8-naphthyridine

Publications (1)

Publication Number Publication Date
DK0391185T3 true DK0391185T3 (da) 1994-04-11

Family

ID=6377950

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90105652.3T DK0391185T3 (da) 1989-04-06 1990-03-24 1,8-Naphthyridiner

Country Status (14)

Country Link
US (1) US5034399A (da)
EP (1) EP0391185B1 (da)
JP (1) JPH02290876A (da)
KR (1) KR900016207A (da)
AT (1) ATE99310T1 (da)
AU (1) AU622010B2 (da)
CA (1) CA2013783A1 (da)
DE (2) DE3911064A1 (da)
DK (1) DK0391185T3 (da)
ES (1) ES2062145T3 (da)
HU (1) HUT53904A (da)
IL (1) IL93988A0 (da)
PT (1) PT93662A (da)
ZA (1) ZA902627B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4022414A1 (de) * 1990-07-13 1992-01-16 Bayer Ag Substituierte pyrrolo-pyridine
EP0497226B1 (en) * 1991-01-29 1999-08-25 Mitsubishi Jukogyo Kabushiki Kaisha Method for producing methanol by use of nuclear heat and power generating plant
DE4405712A1 (de) * 1994-02-23 1995-08-24 Basf Ag Substituierte Naphthyridine und deren Verwendung
DE19627431A1 (de) * 1996-07-08 1998-01-15 Bayer Ag Heterocyclisch kondensierte Pyridine
AR008789A1 (es) 1996-07-31 2000-02-23 Bayer Corp Piridinas y bifenilos substituidos
EP1472228B1 (en) * 2002-01-31 2009-03-25 Novartis AG Process for the manufacture of hmg-coa reductase inhibitors
PL378111A1 (pl) * 2003-02-14 2006-03-06 Smithkline Beecham Corporation Nowe związki
US7420059B2 (en) * 2003-11-20 2008-09-02 Bristol-Myers Squibb Company HMG-CoA reductase inhibitors and method
CA2591053C (en) * 2004-12-23 2011-03-15 Zhejiang Hisun Pharma. Co., Ltd Pyrimidinone compounds and preparation and use thereof
US20100093738A1 (en) * 2006-10-06 2010-04-15 Basf Se Fungicidal Compounds and Fungicidal Compositions
US20210008084A1 (en) 2017-10-16 2021-01-14 Tsinghua University Mevalonate pathway inhibitor and pharmaceutical composition thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA988522A (en) * 1972-05-05 1976-05-04 Haydn W.R. Williams 1,8-naphthyridine compounds
GR69216B (da) * 1979-06-15 1982-05-07 Merck & Co Inc
AU570021B2 (en) * 1982-11-22 1988-03-03 Novartis Ag Analogs of mevalolactone
US4613610A (en) * 1984-06-22 1986-09-23 Sandoz Pharmaceuticals Corp. Cholesterol biosynthesis inhibiting pyrazole analogs of mevalonolactone and its derivatives
PH24782A (en) * 1985-10-24 1990-10-30 Sankyo Co Composition containing a penem or carbapenem antibiotic and the use of the same
AU632461B2 (en) * 1987-07-22 1993-01-07 Schering Corporation Bicyclic compounds, their use as pharmaceuticals, their preparation, and intermediates useful in their preparation
US4761419A (en) * 1987-12-07 1988-08-02 Warner-Lambert Company 6-(((substituted)quinolinyl)ethyl)-and ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis
DE3825611A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte annellierte pyrrole, verfahren sowie zwischenprodukte zu ihrer herstellung, und ihre verwendung in arzneimitteln, insbesondere als hmg-coa-reduktase-inhibitoren
AU634561B2 (en) * 1989-07-27 1993-02-25 Eli Lilly And Company Naphthyridine derivatives

Also Published As

Publication number Publication date
PT93662A (pt) 1990-11-20
ZA902627B (en) 1991-01-30
HU902098D0 (en) 1990-07-28
ES2062145T3 (es) 1994-12-16
EP0391185A1 (de) 1990-10-10
JPH02290876A (ja) 1990-11-30
CA2013783A1 (en) 1990-10-06
HUT53904A (en) 1990-12-28
IL93988A0 (en) 1991-01-31
EP0391185B1 (de) 1993-12-29
KR900016207A (ko) 1990-11-12
ATE99310T1 (de) 1994-01-15
AU5254290A (en) 1990-10-11
DE59003994D1 (de) 1994-02-10
AU622010B2 (en) 1992-03-26
DE3911064A1 (de) 1990-10-11
US5034399A (en) 1991-07-23

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