UA116205C2 - Спосіб кількісного визначення послідовності нуклеїнової кислоти в зразку - Google Patents
Спосіб кількісного визначення послідовності нуклеїнової кислоти в зразкуInfo
- Publication number
- UA116205C2 UA116205C2 UAA201412069A UAA201412069A UA116205C2 UA 116205 C2 UA116205 C2 UA 116205C2 UA A201412069 A UAA201412069 A UA A201412069A UA A201412069 A UAA201412069 A UA A201412069A UA 116205 C2 UA116205 C2 UA 116205C2
- Authority
- UA
- Ukraine
- Prior art keywords
- methods
- sample
- quantifying
- compositions
- nucleic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Botany (AREA)
- Mycology (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261621975P | 2012-04-09 | 2012-04-09 | |
| PCT/US2013/035750 WO2013155056A1 (en) | 2012-04-09 | 2013-04-09 | Compositions and methods for quantifying a nucleic acid sequence in a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA116205C2 true UA116205C2 (uk) | 2018-02-26 |
Family
ID=49328090
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201412069A UA116205C2 (uk) | 2012-04-09 | 2013-04-09 | Спосіб кількісного визначення послідовності нуклеїнової кислоти в зразку |
| UAA201709549A UA125112C2 (uk) | 2012-04-09 | 2013-04-09 | Спосіб ампліфікації полінуклеотиду |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201709549A UA125112C2 (uk) | 2012-04-09 | 2013-04-09 | Спосіб ампліфікації полінуклеотиду |
Country Status (18)
| Country | Link |
|---|---|
| US (8) | US9096897B2 (enExample) |
| EP (3) | EP2836609B2 (enExample) |
| JP (4) | JP5801513B2 (enExample) |
| KR (4) | KR102159818B1 (enExample) |
| CN (2) | CN114134207A (enExample) |
| AU (3) | AU2013246080C1 (enExample) |
| BR (1) | BR112014025262A8 (enExample) |
| CA (1) | CA2869971C (enExample) |
| DK (2) | DK3587587T3 (enExample) |
| ES (2) | ES3011408T3 (enExample) |
| FI (1) | FI3587587T3 (enExample) |
| IN (1) | IN2014DN08831A (enExample) |
| MX (2) | MX367666B (enExample) |
| NZ (2) | NZ701145A (enExample) |
| RU (2) | RU2732589C2 (enExample) |
| UA (2) | UA116205C2 (enExample) |
| WO (1) | WO2013155056A1 (enExample) |
| ZA (3) | ZA201408116B (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12043866B2 (en) | 2010-08-13 | 2024-07-23 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| US9096897B2 (en) | 2012-04-09 | 2015-08-04 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample comprising a primer oligonucleotide with a 3′-terminal region comprising a 2′-modified nucleotide |
| UA123387C2 (uk) | 2014-04-22 | 2021-03-31 | Інвайролоджикс, Інк. | Виділений праймерний олігонуклеотид та спосіб його застосування |
| MX2016014292A (es) * | 2014-04-30 | 2017-02-13 | Envirologix Inc | Composiciones y metodos para detectar la enfermedad del dragon amarillo (huanglongbing). |
| ES2759339T3 (es) * | 2014-10-14 | 2020-05-08 | Abbott Lab | Conversión de secuencia y ADN amplificador de señal que tiene ácidos nucleicos bloqueados y métodos de detección que usan los mismos |
| US10793922B2 (en) * | 2014-10-20 | 2020-10-06 | Envirologix Inc. | Compositions and methods for detecting an RNA virus |
| WO2016122698A1 (en) * | 2015-01-30 | 2016-08-04 | Envirologix, Inc. | Compositions and methods for rapid detection of salmonella |
| DK3250715T3 (da) | 2015-01-30 | 2024-12-09 | Envirologix Inc | Substrat til en klippe- og forlængelsesreaktion omfattende en nukleinsyredupleks |
| EP3314245A4 (en) * | 2015-06-25 | 2019-02-27 | Roswell Biotechnologies, Inc | BIOMOLECULAR SENSORS AND METHOD |
| WO2017014963A1 (en) * | 2015-07-20 | 2017-01-26 | Envirologix Inc. | Compositions and methods for rapid detection of salmonella serovar d1 |
| US20180320228A1 (en) * | 2015-10-30 | 2018-11-08 | Alere Inc. | Determination of polymorphisms using isothermal nucleic acid amplification |
| US10329601B2 (en) | 2015-12-28 | 2019-06-25 | Ionian Technologies, Inc. | Nicking and extension amplification reaction (NEAR) of Streptococcus species |
| EP3408220A4 (en) | 2016-01-28 | 2019-09-04 | Roswell Biotechnologies, Inc | METHOD AND DEVICE FOR MEASURING ANALYTES USING LARGE CALCULAR MOLECULAR ELECTRONIC SENSOR ARRAYS |
| KR102763291B1 (ko) | 2016-01-28 | 2025-02-04 | 로스웰 엠이 아이엔씨. | 대량 병렬 ｄｎａ 시퀀싱 장치 |
| JP6854532B2 (ja) | 2016-02-09 | 2021-04-07 | ロズウェル バイオテクノロジーズ，インコーポレイテッド | 電子的、標識フリーのｄｎａおよびゲノムシークエンシング |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| GB201611469D0 (en) * | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Improvements in or relating to nucleic acid amplification processes |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| EP3568407A4 (en) | 2017-01-10 | 2020-12-23 | Roswell Biotechnologies, Inc | DNA DATA STORAGE METHODS AND SYSTEMS |
| US11656197B2 (en) | 2017-01-19 | 2023-05-23 | Roswell ME Inc. | Solid state sequencing devices comprising two dimensional layer materials |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| KR102879682B1 (ko) | 2017-04-25 | 2025-10-30 | 로스웰 엠이 아이엔씨. | 분자 센서들을 위한 효소 회로들 |
| EP4023764A3 (en) | 2017-05-09 | 2022-09-21 | Roswell Biotechnologies, Inc. | Binding probe circuits for molecular sensors |
| US10538808B2 (en) | 2017-05-26 | 2020-01-21 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
| TWI754652B (zh) * | 2017-07-10 | 2022-02-11 | 英商盧米瑞德克斯英國有限公司 | 核酸擴增方法中或相關之改良 |
| US11371955B2 (en) | 2017-08-30 | 2022-06-28 | Roswell Biotechnologies, Inc. | Processive enzyme molecular electronic sensors for DNA data storage |
| RU2020100221A (ru) * | 2017-08-31 | 2021-09-30 | Иониан Текнолоджис, Ллс | Реакция амплификации с разрывом и удлинением (near) разновидностей респираторно-синцитиального вируса |
| KR102717872B1 (ko) | 2017-10-10 | 2024-10-14 | 로스웰 엠이 아이엔씨. | 무증폭 dna 데이터 저장을 위한 방법, 장치 및 시스템 |
| GB2569965A (en) | 2018-01-04 | 2019-07-10 | Lumiradx Uk Ltd | Improvements in or relating to amplification of nucleic acids |
| CN108588252A (zh) * | 2018-03-29 | 2018-09-28 | 杭州泰熙生物技术有限公司 | 一种寄生虫检测试剂盒及其检测方法 |
| WO2019217704A1 (en) | 2018-05-09 | 2019-11-14 | Vibrant Holdings, Llc | Methods of synthesizing a polynucleotide array using photactivated agents |
| MX2020013461A (es) * | 2018-06-26 | 2021-04-28 | Broad Inst Inc | Composiciones, sistemas y métodos de amplificación basados en la doble nicasa crispr. |
| GB201812149D0 (en) * | 2018-07-25 | 2018-09-05 | Sense Biodetection Ltd | Nucleic acid detection method |
| KR102154628B1 (ko) | 2019-01-03 | 2020-09-10 | 베트올 (주) | 반정량 수평류 면역진단 기술을 이용한 랄스토니아 솔라나세아룸과 푸사리움 옥시스포룸의 동시 진단 방법 |
| KR102199394B1 (ko) * | 2019-07-01 | 2021-01-06 | 한국화학연구원 | 이중분자비콘과 산화그래핀을 포함하는 핵산 검출용 조성물 및 이를 이용한 핵산 검출의 비색신호 증폭 방법 |
| KR102531590B1 (ko) * | 2019-07-16 | 2023-05-11 | 고려대학교 산학협력단 | 절단효소 인식부위의 미러링 결합에 의한 표적핵산의 검출 방법 및 핵산 검출용 조성물 |
| CN110408678A (zh) * | 2019-07-26 | 2019-11-05 | 宁儿医院股份有限公司 | 单管型多重微生物检测体系及其即时检测方法 |
| WO2021226205A1 (en) * | 2020-05-07 | 2021-11-11 | Bioskryb, Inc. | Detection of low abundance nucleic acids |
| US20240301481A1 (en) * | 2021-02-02 | 2024-09-12 | Rhodx, Inc. | Synthetic polynucleotides and methods for selectively amplifying alleles |
| MX2024007068A (es) * | 2021-12-08 | 2024-06-21 | Massachusetts Inst Technology | Amplificacion isotermica a temperatura fria de polinucleotidos. |
| GB2635849A (en) * | 2022-05-14 | 2025-05-28 | Jiangsu Code Biomedical Tech Co Ltd | Novel compositions and methods for cell-free DNA detection |
| KR20250078890A (ko) * | 2022-07-01 | 2025-06-04 | 셜록 바이오사이언스, 인크. | 주위 온도 핵산 증폭 및 검출 |
| WO2024030985A1 (en) | 2022-08-04 | 2024-02-08 | Abbott Laboratories | Assays for detecting monkeypox virus |
| WO2025049450A1 (en) | 2023-08-28 | 2025-03-06 | Abbott Molecular, Inc. | Assays for detecting bk virus (bkv) |
| WO2025049451A1 (en) | 2023-08-28 | 2025-03-06 | Abbott Molecular, Inc. | Assays for detecting cytomegalovirus (cmv) or epstein-bar virus (ebv) |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| WO1994003635A1 (en) | 1992-08-04 | 1994-02-17 | Institute Of Molecular Biology & Biotechnology | Rapid amplification and detection of nucleic acids |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| US5629179A (en) | 1995-03-17 | 1997-05-13 | Novagen, Inc. | Method and kit for making CDNA library |
| AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
| JP2000505312A (ja) * | 1996-03-18 | 2000-05-09 | モレキュラー バイオロジー リソーシーズ，インコーポレイテッド | 標的核酸配列増幅 |
| DE69736667T2 (de) * | 1996-07-16 | 2007-09-06 | Gen-Probe Inc., San Diego | Verfahren zum nachweis und amplifikation von nukleinsäuresequenzen unter verbrauch von modifizierten oligonukleotiden mit erhöhter zielschmelztemperatur (tm) |
| GB9716231D0 (en) | 1997-07-31 | 1997-10-08 | Amersham Int Ltd | Base analogues |
| US6355421B1 (en) | 1997-10-27 | 2002-03-12 | Boston Probes, Inc. | Methods, kits and compositions pertaining to PNA molecular beacons |
| US5952202A (en) | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
| AU1908100A (en) | 1998-11-06 | 2000-05-29 | Molecular Biology Resources, Inc. | Isothermal nucleic acid amplification methods |
| US6436677B1 (en) | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
| WO2001090415A2 (en) | 2000-05-20 | 2001-11-29 | The Regents Of The University Of Michigan | Method of producing a dna library using positional amplification |
| US6191267B1 (en) | 2000-06-02 | 2001-02-20 | New England Biolabs, Inc. | Cloning and producing the N.BstNBI nicking endonuclease |
| DE60115811T2 (de) * | 2000-10-25 | 2006-08-03 | Roche Diagnostics Gmbh | Amplifizierung unter Verwendung von modifizierten Primern |
| EP1353936A4 (en) | 2000-12-27 | 2005-05-18 | Invitrogen Corp | PRIMER AND METHOD FOR THE DETECTION AND DISTINCTION OF NUCLEIC ACIDS |
| WO2003008622A2 (en) | 2001-07-15 | 2003-01-30 | Keck Graduate Institute | Exponential nucleic acid amplification using nicking endonucleases |
| CA2492220C (en) | 2001-07-15 | 2014-03-18 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
| JPWO2003016569A1 (ja) * | 2001-08-20 | 2004-12-02 | タカラバイオ株式会社 | 核酸の増幅方法 |
| US6977148B2 (en) | 2001-10-15 | 2005-12-20 | Qiagen Gmbh | Multiple displacement amplification |
| US6617137B2 (en) | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US20030211483A1 (en) | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
| US7662594B2 (en) | 2002-09-20 | 2010-02-16 | New England Biolabs, Inc. | Helicase-dependent amplification of RNA |
| JP4632788B2 (ja) | 2002-09-20 | 2011-02-16 | ニュー・イングランド・バイオラブズ・インコーポレイティッド | 核酸のヘリカーゼ依存性増幅 |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| JP4380305B2 (ja) | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるｌ−アミノ酸の製造法 |
| WO2005087952A1 (en) | 2004-03-05 | 2005-09-22 | The Regents Of The University Of California | Methods and compositions relating to the pharmacogenetics of abcc2, ugt1a1, and/or slc01b1 gene variants |
| US20060115838A1 (en) | 2004-10-19 | 2006-06-01 | Trevigen Inc. | Real-time detection of amplicons using nucleic acid repair enzymes |
| EP2319940A1 (en) | 2005-01-04 | 2011-05-11 | Hitachi Chemical Company, Ltd. | Primer generation rolling circle amplification |
| JP4555136B2 (ja) * | 2005-03-31 | 2010-09-29 | 本田技研工業株式会社 | 燃料電池の電気システム、燃料電池車両及び電力供給方法 |
| EP2829615B1 (en) | 2005-07-25 | 2018-05-09 | Alere San Diego, Inc. | Kit for multiplexing recombinase polymerase amplification |
| US20070031857A1 (en) | 2005-08-02 | 2007-02-08 | Rubicon Genomics, Inc. | Compositions and methods for processing and amplification of DNA, including using multiple enzymes in a single reaction |
| EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| US7947286B2 (en) | 2005-10-07 | 2011-05-24 | Panthera Biopharma Llc | Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain |
| US20090092967A1 (en) * | 2006-06-26 | 2009-04-09 | Epoch Biosciences, Inc. | Method for generating target nucleic acid sequences |
| US20080096257A1 (en) | 2006-08-15 | 2008-04-24 | Zuxu Yao | Methods for Rapid, Single-Step Strand Displacement Amplification of Nucleic Acids |
| DE102006039396A1 (de) | 2006-08-22 | 2008-03-13 | Robert Bosch Gmbh | Laserlichtquelle |
| WO2008042067A2 (en) | 2006-09-28 | 2008-04-10 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
| AU2007304776A1 (en) | 2006-10-06 | 2008-04-10 | Dna Genotek Inc. | Stabilizing compositions and methods for extraction of ribonucleic acid |
| JP2008136451A (ja) | 2006-12-05 | 2008-06-19 | Hitachi Ltd | 核酸増幅法 |
| US8202972B2 (en) | 2007-01-10 | 2012-06-19 | General Electric Company | Isothermal DNA amplification |
| US20090081760A1 (en) † | 2007-01-12 | 2009-03-26 | Monsanto Technology Llc | Dmo methods and compositions |
| US20080254458A1 (en) | 2007-04-10 | 2008-10-16 | Asiagen Corporation | Method of pre-treating in pleural effusion for detection of Mycobacterium tuberculosis |
| US20080274458A1 (en) | 2007-05-01 | 2008-11-06 | Latham Gary J | Nucleic acid quantitation methods |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| WO2009020609A2 (en) | 2007-08-06 | 2009-02-12 | Nanogen, Inc. | Isolation of nucleic acids molecules using modified solid supports |
| US20090197254A1 (en) | 2007-12-14 | 2009-08-06 | Ming-Chou Lee | Variant scorpion primers for nucleic acid amplification and detection |
| US20090325169A1 (en) * | 2008-04-30 | 2009-12-31 | Integrated Dna Technologies, Inc. | Rnase h-based assays utilizing modified rna monomers |
| WO2010026933A1 (ja) | 2008-09-03 | 2010-03-11 | タカラバイオ株式会社 | Ｒｎａ検出用組成物 |
| US20120021461A1 (en) | 2009-01-21 | 2012-01-26 | Human Genetic Signatures Pty. Ltd. | Isothermal strand displacement amplification |
| WO2010107946A2 (en) | 2009-03-18 | 2010-09-23 | Sequenom, Inc. | Use of thermostable endonucleases for generating reporter molecules |
| WO2010126913A1 (en) | 2009-04-27 | 2010-11-04 | Gen-Probe Incorporated | Methods and kits for use in the selective amplification of target sequences |
| US12043866B2 (en) * | 2010-08-13 | 2024-07-23 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| EP2420579A1 (en) | 2010-08-17 | 2012-02-22 | QIAGEN GmbH | Helicase dependent isothermal amplification using nicking enzymes |
| CA2849023C (en) | 2011-09-15 | 2022-07-19 | David A. Shafer | Probe:antiprobe compositions for high specificity dna or rna detection |
| EP2798089B1 (en) | 2011-12-30 | 2018-05-23 | Bio-rad Laboratories, Inc. | Methods and compositions for performing nucleic acid amplification reactions |
| US9096897B2 (en) | 2012-04-09 | 2015-08-04 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample comprising a primer oligonucleotide with a 3′-terminal region comprising a 2′-modified nucleotide |
| WO2014004852A2 (en) | 2012-06-29 | 2014-01-03 | General Electric Company | Kit for isothermal dna amplification starting from an rna template |
| JP2014082936A (ja) | 2012-10-19 | 2014-05-12 | Kyoto Univ | 変異型逆転写酵素 |
| UA123387C2 (uk) | 2014-04-22 | 2021-03-31 | Інвайролоджикс, Інк. | Виділений праймерний олігонуклеотид та спосіб його застосування |
| MX2016014292A (es) | 2014-04-30 | 2017-02-13 | Envirologix Inc | Composiciones y metodos para detectar la enfermedad del dragon amarillo (huanglongbing). |
| US10793922B2 (en) | 2014-10-20 | 2020-10-06 | Envirologix Inc. | Compositions and methods for detecting an RNA virus |
| WO2016069345A1 (en) | 2014-10-28 | 2016-05-06 | Envirologix Inc. | Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis |
| WO2016122698A1 (en) | 2015-01-30 | 2016-08-04 | Envirologix, Inc. | Compositions and methods for rapid detection of salmonella |
-
2013
- 2013-04-09 US US14/342,766 patent/US9096897B2/en active Active
- 2013-04-09 KR KR1020197034264A patent/KR102159818B1/ko active Active
- 2013-04-09 UA UAA201412069A patent/UA116205C2/uk unknown
- 2013-04-09 CN CN202111049886.5A patent/CN114134207A/zh active Pending
- 2013-04-09 UA UAA201709549A patent/UA125112C2/uk unknown
- 2013-04-09 IN IN8831DEN2014 patent/IN2014DN08831A/en unknown
- 2013-04-09 RU RU2016138585A patent/RU2732589C2/ru active
- 2013-04-09 MX MX2016004384A patent/MX367666B/es unknown
- 2013-04-09 NZ NZ701145A patent/NZ701145A/en unknown
- 2013-04-09 BR BR112014025262A patent/BR112014025262A8/pt not_active Application Discontinuation
- 2013-04-09 CA CA2869971A patent/CA2869971C/en active Active
- 2013-04-09 FI FIEP19175608.9T patent/FI3587587T3/fi active
- 2013-04-09 DK DK19175608.9T patent/DK3587587T3/da active
- 2013-04-09 EP EP13775206.9A patent/EP2836609B2/en active Active
- 2013-04-09 ES ES19175608T patent/ES3011408T3/es active Active
- 2013-04-09 NZ NZ723570A patent/NZ723570A/en unknown
- 2013-04-09 JP JP2015505849A patent/JP5801513B2/ja active Active
- 2013-04-09 KR KR1020207027096A patent/KR102362649B1/ko active Active
- 2013-04-09 RU RU2014144722/10A patent/RU2601129C2/ru active
- 2013-04-09 CN CN201380029891.7A patent/CN104685066B/zh active Active
- 2013-04-09 KR KR1020157016789A patent/KR102048946B1/ko active Active
- 2013-04-09 ES ES13775206T patent/ES2743050T5/es active Active
- 2013-04-09 AU AU2013246080A patent/AU2013246080C1/en active Active
- 2013-04-09 DK DK13775206.9T patent/DK2836609T4/da active
- 2013-04-09 KR KR1020147031343A patent/KR101570951B1/ko active Active
- 2013-04-09 EP EP19175608.9A patent/EP3587587B1/en active Active
- 2013-04-09 WO PCT/US2013/035750 patent/WO2013155056A1/en not_active Ceased
- 2013-04-09 MX MX2014012214A patent/MX338296B/es active IP Right Grant
- 2013-04-09 EP EP24210836.3A patent/EP4524265A3/en active Pending
-
2014
- 2014-11-06 ZA ZA2014/08116A patent/ZA201408116B/en unknown
-
2015
- 2015-07-01 US US14/789,545 patent/US9322053B2/en active Active
- 2015-08-26 JP JP2015166615A patent/JP6169660B2/ja active Active
- 2015-10-19 AU AU2015246059A patent/AU2015246059B2/en active Active
- 2015-11-05 ZA ZA2015/08197A patent/ZA201508197B/en unknown
-
2016
- 2016-01-06 US US14/989,687 patent/US9631231B2/en active Active
- 2016-08-25 JP JP2016164716A patent/JP6321738B2/ja active Active
- 2016-11-04 ZA ZA2016/07642A patent/ZA201607642B/en unknown
-
2017
- 2017-02-21 US US15/438,330 patent/US20170166960A1/en not_active Abandoned
- 2017-06-28 JP JP2017125772A patent/JP6480511B2/ja active Active
- 2017-11-09 US US15/808,442 patent/US10077467B2/en active Active
-
2018
- 2018-03-07 AU AU2018201671A patent/AU2018201671B2/en active Active
- 2018-08-30 US US16/117,949 patent/US10584376B2/en active Active - Reinstated
-
2020
- 2020-02-05 US US16/782,805 patent/US11208687B2/en active Active
-
2021
- 2021-11-15 US US17/526,638 patent/US11866773B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX338296B (es) | Composiciones y metodos para cuantificar una secuencia de acido nucleico en una muestra. | |
| GB201317477D0 (en) | Methods, compositions and kits for determing the presence/absnece of a variant nucleic acid sequence | |
| WO2012021493A3 (en) | Compositions and methods for quantifying a nucleic acid sequence in a sample | |
| EP2746395A4 (en) | PRIMER SET, METHOD FOR AMPLIFYING TARGET NUCLEIC ACID SEQUENCE USING THE SAME, AND METHOD FOR DETECTING NUCLEIC ACID MUTRED USING THE SAME | |
| MX353840B (es) | Deteccion de acidos nucleicos. | |
| IL233773B (en) | Methods for identifying a target sequence of a nucleic acid from DNA or a mixture of nucleic acids and a kit for performing these methods | |
| GB201219137D0 (en) | Direct nucleic acid amplification kit, reagent and method | |
| WO2016064894A3 (en) | Compositions and methods for detecting an rna virus | |
| EP3862439A3 (en) | Liver cancer detection kit or device, and detection method | |
| EP3967769A3 (en) | Lung cancer detection kit or device, and detection method | |
| EP3971299A3 (en) | Colorectal cancer detection kit or device, and detection method | |
| WO2015058008A3 (en) | Enhanced nucleic acid identification and detection | |
| AR080009A1 (es) | Alteracion genomica objetivo utilizando nucleasas de dedos de zinc | |
| EP3757225A3 (en) | Pancreatic cancer detection kit or device, and detection method | |
| EP4461824A3 (en) | Detection kit or device and detection method for biliary tract cancer | |
| EP4495266A3 (en) | Esophageal cancer detection kit or device, and detection method | |
| MX376755B (es) | Detección de ácidos nucleicos diana mediante el uso de hibridación. | |
| WO2014005125A3 (en) | Fluorescent compounds and uses thereof | |
| IN2015DN02479A (enExample) | ||
| WO2012027572A3 (en) | Methods for nucleic acid capture and sequencing | |
| MX2015001961A (es) | Metodos y sistemas para ensayos. | |
| EP3216852A4 (en) | Method for introducing nucleic acid, method for detecting nucleic acid, method for analyzing biological component, array device for biological component assay, and kit for analyzing biological component | |
| ZA201405894B (en) | Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay | |
| SG11201602686YA (en) | Pcr primer set for bacterial dna amplification, kit for detecting and/or identifying bacterial species, and method for detecting and/or identifying bacterial species | |
| EP4524262A3 (en) | Compositions and methods for enhancing and/or predicting dna amplification |