MX367666B - Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra. - Google Patents
Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra.Info
- Publication number
- MX367666B MX367666B MX2016004384A MX2016004384A MX367666B MX 367666 B MX367666 B MX 367666B MX 2016004384 A MX2016004384 A MX 2016004384A MX 2016004384 A MX2016004384 A MX 2016004384A MX 367666 B MX367666 B MX 367666B
- Authority
- MX
- Mexico
- Prior art keywords
- methods
- sample
- quantifying
- compositions
- nucleic acid
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 title 1
- 150000007523 nucleic acids Chemical group 0.000 title 1
- 108091034117 Oligonucleotide Proteins 0.000 abstract 2
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6851—Quantitative amplification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/6895—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Botany (AREA)
- Mycology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a composiciones y métodos para cuantificar la detección de un oligonucleótido objetivo en una muestra en tiempo real. Estos métodos son compatibles con los oligonucleótidos objetivo amplificados al utilizar una reacción NEAR.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261621975P | 2012-04-09 | 2012-04-09 | |
| PCT/US2013/035750 WO2013155056A1 (en) | 2012-04-09 | 2013-04-09 | Compositions and methods for quantifying a nucleic acid sequence in a sample |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX367666B true MX367666B (es) | 2019-08-30 |
Family
ID=49328090
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014012214A MX338296B (es) | 2012-04-09 | 2013-04-09 | Composiciones y metodos para cuantificar una secuencia de acido nucleico en una muestra. |
| MX2016004384A MX367666B (es) | 2012-04-09 | 2013-04-09 | Composiciones y métodos para cuantificar una secuencia de ácido nucleico en una muestra. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2014012214A MX338296B (es) | 2012-04-09 | 2013-04-09 | Composiciones y metodos para cuantificar una secuencia de acido nucleico en una muestra. |
Country Status (18)
| Country | Link |
|---|---|
| US (8) | US9096897B2 (es) |
| EP (3) | EP3587587B1 (es) |
| JP (4) | JP5801513B2 (es) |
| KR (4) | KR102362649B1 (es) |
| CN (2) | CN104685066B (es) |
| AU (3) | AU2013246080C1 (es) |
| BR (1) | BR112014025262A8 (es) |
| CA (1) | CA2869971C (es) |
| DK (2) | DK2836609T4 (es) |
| ES (2) | ES2743050T5 (es) |
| FI (1) | FI3587587T3 (es) |
| IN (1) | IN2014DN08831A (es) |
| MX (2) | MX338296B (es) |
| NZ (2) | NZ701145A (es) |
| RU (2) | RU2601129C2 (es) |
| UA (2) | UA125112C2 (es) |
| WO (1) | WO2013155056A1 (es) |
| ZA (3) | ZA201408116B (es) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012021493A2 (en) | 2010-08-13 | 2012-02-16 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| RU2601129C2 (ru) | 2012-04-09 | 2016-10-27 | Инвайролоджикс Инк. | Композиции и способы для количественного определения последовательности нуклеиновой кислоты в образце |
| EP3748011B1 (en) | 2014-04-22 | 2024-11-13 | Envirologix Inc. | Compositions and methods for enhancing and/or predicting dna amplification |
| US10100370B2 (en) | 2014-04-30 | 2018-10-16 | Envirologix Inc. | Compositions and methods for detecting huanglongbing |
| ES2759337T3 (es) * | 2014-10-14 | 2020-05-08 | Abbott Lab | ADN de conversión de secuencia y ADN amplificador de señal que tiene secuencias espaciadoras de poli-ADN y métodos de detección que los utilizan |
| CN107208137A (zh) | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
| EP3250709B1 (en) * | 2015-01-30 | 2019-12-25 | Envirologix Inc. | Compositions and methods for rapid detection of salmonella |
| RU2755495C2 (ru) * | 2015-01-30 | 2021-09-16 | Инвайролоджикс Инк. | Молекула субстрата |
| CA3021580A1 (en) * | 2015-06-25 | 2016-12-29 | Barry L. Merriman | Biomolecular sensors and methods |
| BR112018001222A2 (pt) * | 2015-07-20 | 2018-09-25 | Envirologix Inc. | composições e métodos para a detecção rápida de salmonella serovar d1. |
| ES3063374T3 (en) * | 2015-10-30 | 2026-04-16 | Abbott Diagnostics Scarborough Inc | Determination of polymorphisms using isothermal nucleic acid amplification |
| US10329601B2 (en) | 2015-12-28 | 2019-06-25 | Ionian Technologies, Inc. | Nicking and extension amplification reaction (NEAR) of Streptococcus species |
| CA3050062A1 (en) | 2016-01-14 | 2017-07-20 | Roswell Biotechnologies, Inc. | Molecular sensors and related methods |
| JP7280590B2 (ja) | 2016-01-28 | 2023-05-24 | ロズウェル バイオテクノロジーズ,インコーポレイテッド | 大スケールの分子電子工学センサアレイを使用する被分析物を測定するための方法および装置 |
| EP3408219B1 (en) | 2016-01-28 | 2022-08-17 | Roswell Biotechnologies, Inc | Massively parallel dna sequencing apparatus |
| US10737263B2 (en) | 2016-02-09 | 2020-08-11 | Roswell Biotechnologies, Inc. | Electronic label-free DNA and genome sequencing |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| GB201611469D0 (en) * | 2016-06-30 | 2016-08-17 | Lumiradx Tech Ltd | Improvements in or relating to nucleic acid amplification processes |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| WO2018132457A1 (en) | 2017-01-10 | 2018-07-19 | Roswell Biotechnologies, Inc. | Methods and systems for dna data storage |
| CN110520517A (zh) | 2017-01-19 | 2019-11-29 | 罗斯威尔生命技术公司 | 包括二维层材料的固态测序装置 |
| KR102879682B1 (ko) | 2017-04-25 | 2025-10-30 | 로스웰 엠이 아이엔씨. | 분자 센서들을 위한 효소 회로들 |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| CA3057155A1 (en) | 2017-05-09 | 2018-11-15 | Roswell Biotechnologies, Inc. | Binding probe circuits for molecular sensors |
| US10538808B2 (en) | 2017-05-26 | 2020-01-21 | Vibrant Holdings, Llc | Photoactive compounds and methods for biomolecule detection and sequencing |
| TWI754652B (zh) * | 2017-07-10 | 2022-02-11 | 英商盧米瑞德克斯英國有限公司 | 核酸擴增方法中或相關之改良 |
| EP3676389A4 (en) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | PROCESSIVE ENZYMATIC MOLECULAR ELECTRONIC SENSORS FOR STORING DNA DATA |
| KR20200083444A (ko) * | 2017-08-31 | 2020-07-08 | 아이오니안 테크놀로지스, 엘엘씨 | 호흡기 세포융합 바이러스 종의 니킹 및 연장 증폭 반응(near) |
| EP3694990A4 (en) | 2017-10-10 | 2022-06-15 | Roswell Biotechnologies, Inc. | METHODS, DEVICE AND SYSTEMS FOR AMPLIFICATION-FREE DNA DATA STORAGE |
| GB2569965A (en) | 2018-01-04 | 2019-07-10 | Lumiradx Uk Ltd | Improvements in or relating to amplification of nucleic acids |
| CN108588252A (zh) * | 2018-03-29 | 2018-09-28 | 杭州泰熙生物技术有限公司 | 一种寄生虫检测试剂盒及其检测方法 |
| AU2019266303B2 (en) | 2018-05-09 | 2025-12-18 | Vibrant Holdings, Llc | Methods of synthesizing a polynucleotide array using photactivated agents |
| AU2019291827A1 (en) * | 2018-06-26 | 2020-12-24 | Massachusetts Institute Of Technology | Crispr double nickase based amplification compositions, systems, and methods |
| GB201812149D0 (en) | 2018-07-25 | 2018-09-05 | Sense Biodetection Ltd | Nucleic acid detection method |
| KR102154628B1 (ko) | 2019-01-03 | 2020-09-10 | 베트올 (주) | 반정량 수평류 면역진단 기술을 이용한 랄스토니아 솔라나세아룸과 푸사리움 옥시스포룸의 동시 진단 방법 |
| KR102199394B1 (ko) * | 2019-07-01 | 2021-01-06 | 한국화학연구원 | 이중분자비콘과 산화그래핀을 포함하는 핵산 검출용 조성물 및 이를 이용한 핵산 검출의 비색신호 증폭 방법 |
| KR102531590B1 (ko) * | 2019-07-16 | 2023-05-11 | 고려대학교 산학협력단 | 절단효소 인식부위의 미러링 결합에 의한 표적핵산의 검출 방법 및 핵산 검출용 조성물 |
| CN110408678A (zh) * | 2019-07-26 | 2019-11-05 | 宁儿医院股份有限公司 | 单管型多重微生物检测体系及其即时检测方法 |
| CN115968408A (zh) * | 2020-05-07 | 2023-04-14 | 铂赛基因组学公司 | 低丰度核酸的检测 |
| AU2022216246A1 (en) * | 2021-02-02 | 2023-09-14 | Rhodx, Inc. | Synthetic polynucleotides and methods for selectively amplifying alleles |
| EP4444907A4 (en) * | 2021-12-08 | 2025-12-03 | Massachusetts Inst Technology | COLD ISOTHERMAL AMPLIFICATION OF POLYNUCLEOTIDES |
| JP2025516389A (ja) * | 2022-05-14 | 2025-05-27 | ジャンスー コード バイオメディカル テクノロジー カンパニー リミテッド | 無細胞dna検出のための新規組成物および方法 |
| US20260043073A1 (en) * | 2022-07-01 | 2026-02-12 | Sherlock Biosciences, Inc. | Ambient temperature nucleic acid amplification and detection |
| EP4565720A1 (en) | 2022-08-04 | 2025-06-11 | Abbott Laboratories | Assays for detecting monkeypox virus |
| WO2025049451A1 (en) | 2023-08-28 | 2025-03-06 | Abbott Molecular, Inc. | Assays for detecting cytomegalovirus (cmv) or epstein-bar virus (ebv) |
| WO2025049450A1 (en) | 2023-08-28 | 2025-03-06 | Abbott Molecular, Inc. | Assays for detecting bk virus (bkv) |
| WO2026085532A1 (en) * | 2024-10-18 | 2026-04-23 | Medix Biotechnologies Inc. | Methods for amplification of nucleic acids |
Family Cites Families (65)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5455166A (en) | 1991-01-31 | 1995-10-03 | Becton, Dickinson And Company | Strand displacement amplification |
| WO1994003635A1 (en) | 1992-08-04 | 1994-02-17 | Institute Of Molecular Biology & Biotechnology | Rapid amplification and detection of nucleic acids |
| US5648211A (en) | 1994-04-18 | 1997-07-15 | Becton, Dickinson And Company | Strand displacement amplification using thermophilic enzymes |
| US5629179A (en) | 1995-03-17 | 1997-05-13 | Novagen, Inc. | Method and kit for making CDNA library |
| AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
| CA2249717A1 (en) * | 1996-03-18 | 1997-09-25 | Richard K. Wilkosz | Target nucleic acid sequence amplification |
| JP2000514307A (ja) * | 1996-07-16 | 2000-10-31 | ジェン―プローブ・インコーポレーテッド | 増加した標的特異的t▲下m▼を持つ修飾オリゴヌクレオチドを用いた核酸配列の検出および増幅のための方法 |
| GB9716231D0 (en) | 1997-07-31 | 1997-10-08 | Amersham Int Ltd | Base analogues |
| ATE478090T1 (de) | 1997-10-27 | 2010-09-15 | Boston Probes Inc | SICH AUF ßPNA MOLECULAR BEACONSß BEZIEHENDE VERFAHREN, TESTSÄTZE UND ZUSAMMENSETZUNGEN |
| US5952202A (en) | 1998-03-26 | 1999-09-14 | The Perkin Elmer Corporation | Methods using exogenous, internal controls and analogue blocks during nucleic acid amplification |
| WO2000028084A1 (en) | 1998-11-06 | 2000-05-18 | Molecular Biology Resources, Inc. | Isothermal nucleic acid amplification methods |
| US6436677B1 (en) | 2000-03-02 | 2002-08-20 | Promega Corporation | Method of reverse transcription |
| EP1290225A4 (en) * | 2000-05-20 | 2004-09-15 | Univ Michigan | METHOD FOR PRODUCING A DNA BANK BY POSITIONAL REPRODUCTION |
| US6191267B1 (en) | 2000-06-02 | 2001-02-20 | New England Biolabs, Inc. | Cloning and producing the N.BstNBI nicking endonuclease |
| DE60115811T2 (de) * | 2000-10-25 | 2006-08-03 | Roche Diagnostics Gmbh | Amplifizierung unter Verwendung von modifizierten Primern |
| WO2002057479A2 (en) | 2000-12-27 | 2002-07-25 | Invitrogen Corporation | Primers and methods for the detection and discrimination of nucleic acids |
| US20030138800A1 (en) | 2001-07-15 | 2003-07-24 | Keck Graduate Institute | Exponential amplification of nucleic acids using nicking agents |
| WO2003008624A2 (en) * | 2001-07-15 | 2003-01-30 | Keck Graduate Institute | Nucleic acid amplification using nicking agents |
| EA006066B1 (ru) * | 2001-08-20 | 2005-08-25 | Такара Био Инк. | Способы амплификации нуклеиновых кислот |
| US6617137B2 (en) | 2001-10-15 | 2003-09-09 | Molecular Staging Inc. | Method of amplifying whole genomes without subjecting the genome to denaturing conditions |
| US6977148B2 (en) | 2001-10-15 | 2005-12-20 | Qiagen Gmbh | Multiple displacement amplification |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US20030211483A1 (en) | 2002-05-09 | 2003-11-13 | Schroeder Benjamin G. | Methods for the enrichment of low-abundance polynucleotides |
| US7662594B2 (en) | 2002-09-20 | 2010-02-16 | New England Biolabs, Inc. | Helicase-dependent amplification of RNA |
| CA2498764C (en) | 2002-09-20 | 2015-11-10 | New England Biolabs, Inc. | Helicase dependent amplification of nucleic acids |
| WO2004067726A2 (en) | 2003-01-29 | 2004-08-12 | Keck Graduate Institute | Isothermal reactions for the amplification of oligonucleotides |
| JP4380305B2 (ja) | 2003-11-21 | 2009-12-09 | 味の素株式会社 | 発酵法によるl−アミノ酸の製造法 |
| WO2005087952A1 (en) | 2004-03-05 | 2005-09-22 | The Regents Of The University Of California | Methods and compositions relating to the pharmacogenetics of abcc2, ugt1a1, and/or slc01b1 gene variants |
| US20060115838A1 (en) | 2004-10-19 | 2006-06-01 | Trevigen Inc. | Real-time detection of amplicons using nucleic acid repair enzymes |
| EP1833994A4 (en) * | 2005-01-04 | 2009-09-02 | Hitachi Chemical Co Ltd | ROLLING CIRCLE GAINING OF A PRIMER GENERATION |
| JP4555136B2 (ja) * | 2005-03-31 | 2010-09-29 | 本田技研工業株式会社 | 燃料電池の電気システム、燃料電池車両及び電力供給方法 |
| WO2007096702A2 (en) | 2005-07-25 | 2007-08-30 | Asm Scientific, Inc. | Methods for multiplexing recombinase polymerase amplification |
| WO2007018601A1 (en) | 2005-08-02 | 2007-02-15 | Rubicon Genomics, Inc. | Compositions and methods for processing and amplification of dna, including using multiple enzymes in a single reaction |
| EP1762627A1 (de) | 2005-09-09 | 2007-03-14 | Qiagen GmbH | Verfahren zur Aktivierung einer Nukleinsäure für eine Polymerase-Reaktion |
| US7947286B2 (en) | 2005-10-07 | 2011-05-24 | Panthera Biopharma Llc | Drosophila cell lines producing recombinant secretable filovirus surface glycoproteins lacking the membrane spanning domain |
| US20090092967A1 (en) * | 2006-06-26 | 2009-04-09 | Epoch Biosciences, Inc. | Method for generating target nucleic acid sequences |
| US20080096257A1 (en) | 2006-08-15 | 2008-04-24 | Zuxu Yao | Methods for Rapid, Single-Step Strand Displacement Amplification of Nucleic Acids |
| DE102006039396A1 (de) | 2006-08-22 | 2008-03-13 | Robert Bosch Gmbh | Laserlichtquelle |
| WO2008042067A2 (en) | 2006-09-28 | 2008-04-10 | Illumina, Inc. | Compositions and methods for nucleotide sequencing |
| AU2007304776A1 (en) | 2006-10-06 | 2008-04-10 | Dna Genotek Inc. | Stabilizing compositions and methods for extraction of ribonucleic acid |
| JP2008136451A (ja) | 2006-12-05 | 2008-06-19 | Hitachi Ltd | 核酸増幅法 |
| US8202972B2 (en) | 2007-01-10 | 2012-06-19 | General Electric Company | Isothermal DNA amplification |
| CL2008000083A1 (es) † | 2007-01-12 | 2008-07-18 | Monsanto Technology Llc Soc Or | Polipeptido cristalizado de dicamba monooxigenasa (dmo); molecula que comprende una superficie de union para dicamba; celula vegetal que comprende dmo. |
| US20080254458A1 (en) | 2007-04-10 | 2008-10-16 | Asiagen Corporation | Method of pre-treating in pleural effusion for detection of Mycobacterium tuberculosis |
| US20080274458A1 (en) | 2007-05-01 | 2008-11-06 | Latham Gary J | Nucleic acid quantitation methods |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| US20090048439A1 (en) | 2007-08-06 | 2009-02-19 | Weisburg William G | Isolation of nucleic acids molecules using modified solid supports |
| US20090197254A1 (en) | 2007-12-14 | 2009-08-06 | Ming-Chou Lee | Variant scorpion primers for nucleic acid amplification and detection |
| EP2644708B1 (en) * | 2008-04-30 | 2014-12-17 | Integrated Dna Technologies, Inc. | RNASE-H-based assays utilizing modified RNA monomers |
| EP2333109B1 (en) | 2008-09-03 | 2013-08-07 | Takara Bio, Inc. | Composition for detection of rna |
| CA2749939A1 (en) | 2009-01-21 | 2010-07-29 | Human Genetic Signatures Pty Ltd | Improved isothermal strand displacement amplification |
| CA2755615A1 (en) | 2009-03-18 | 2010-09-23 | Sequenom, Inc. | Use of thermostable endonucleases for generating reporter molecules |
| WO2010126913A1 (en) | 2009-04-27 | 2010-11-04 | Gen-Probe Incorporated | Methods and kits for use in the selective amplification of target sequences |
| WO2012021493A2 (en) * | 2010-08-13 | 2012-02-16 | Envirologix Inc. | Compositions and methods for quantifying a nucleic acid sequence in a sample |
| EP2420579A1 (en) * | 2010-08-17 | 2012-02-22 | QIAGEN GmbH | Helicase dependent isothermal amplification using nicking enzymes |
| CN103946398B (zh) | 2011-09-15 | 2019-08-13 | 健能泰格技术公司 | 探针:反义探针组合物对高特异性dna或rna的检测 |
| WO2013101783A2 (en) | 2011-12-30 | 2013-07-04 | Bio-Rad Laboratories, Inc. | Methods and compositions for performing nucleic acid amplification reactions |
| RU2601129C2 (ru) | 2012-04-09 | 2016-10-27 | Инвайролоджикс Инк. | Композиции и способы для количественного определения последовательности нуклеиновой кислоты в образце |
| CA2877368C (en) | 2012-06-29 | 2021-07-13 | General Electric Company | Kit for isothermal dna amplification starting from an rna template |
| JP2014082936A (ja) | 2012-10-19 | 2014-05-12 | Kyoto Univ | 変異型逆転写酵素 |
| EP3748011B1 (en) | 2014-04-22 | 2024-11-13 | Envirologix Inc. | Compositions and methods for enhancing and/or predicting dna amplification |
| US10100370B2 (en) | 2014-04-30 | 2018-10-16 | Envirologix Inc. | Compositions and methods for detecting huanglongbing |
| CN107208137A (zh) | 2014-10-20 | 2017-09-26 | 龙公司 | 检测rna病毒的组合物和方法 |
| CA2965657A1 (en) | 2014-10-28 | 2016-05-06 | Envirologix Inc. | Sample preparation vessels, microfluidic circuits, and systems and methods for sample preparation, extraction, and analysis |
| EP3250709B1 (en) | 2015-01-30 | 2019-12-25 | Envirologix Inc. | Compositions and methods for rapid detection of salmonella |
-
2013
- 2013-04-09 RU RU2014144722/10A patent/RU2601129C2/ru active
- 2013-04-09 KR KR1020207027096A patent/KR102362649B1/ko active Active
- 2013-04-09 IN IN8831DEN2014 patent/IN2014DN08831A/en unknown
- 2013-04-09 WO PCT/US2013/035750 patent/WO2013155056A1/en not_active Ceased
- 2013-04-09 UA UAA201709549A patent/UA125112C2/uk unknown
- 2013-04-09 KR KR1020157016789A patent/KR102048946B1/ko active Active
- 2013-04-09 NZ NZ701145A patent/NZ701145A/en unknown
- 2013-04-09 CN CN201380029891.7A patent/CN104685066B/zh active Active
- 2013-04-09 RU RU2016138585A patent/RU2732589C2/ru active
- 2013-04-09 BR BR112014025262A patent/BR112014025262A8/pt not_active Application Discontinuation
- 2013-04-09 MX MX2014012214A patent/MX338296B/es active IP Right Grant
- 2013-04-09 MX MX2016004384A patent/MX367666B/es unknown
- 2013-04-09 EP EP19175608.9A patent/EP3587587B1/en active Active
- 2013-04-09 ES ES13775206T patent/ES2743050T5/es active Active
- 2013-04-09 DK DK13775206.9T patent/DK2836609T4/da active
- 2013-04-09 UA UAA201412069A patent/UA116205C2/uk unknown
- 2013-04-09 FI FIEP19175608.9T patent/FI3587587T3/fi active
- 2013-04-09 ES ES19175608T patent/ES3011408T3/es active Active
- 2013-04-09 DK DK19175608.9T patent/DK3587587T3/da active
- 2013-04-09 US US14/342,766 patent/US9096897B2/en active Active
- 2013-04-09 KR KR1020147031343A patent/KR101570951B1/ko active Active
- 2013-04-09 EP EP24210836.3A patent/EP4524265A3/en active Pending
- 2013-04-09 EP EP13775206.9A patent/EP2836609B2/en active Active
- 2013-04-09 AU AU2013246080A patent/AU2013246080C1/en active Active
- 2013-04-09 JP JP2015505849A patent/JP5801513B2/ja active Active
- 2013-04-09 CA CA2869971A patent/CA2869971C/en active Active
- 2013-04-09 CN CN202111049886.5A patent/CN114134207A/zh active Pending
- 2013-04-09 NZ NZ723570A patent/NZ723570A/en unknown
- 2013-04-09 KR KR1020197034264A patent/KR102159818B1/ko active Active
-
2014
- 2014-11-06 ZA ZA2014/08116A patent/ZA201408116B/en unknown
-
2015
- 2015-07-01 US US14/789,545 patent/US9322053B2/en active Active
- 2015-08-26 JP JP2015166615A patent/JP6169660B2/ja active Active
- 2015-10-19 AU AU2015246059A patent/AU2015246059B2/en active Active
- 2015-11-05 ZA ZA2015/08197A patent/ZA201508197B/en unknown
-
2016
- 2016-01-06 US US14/989,687 patent/US9631231B2/en active Active
- 2016-08-25 JP JP2016164716A patent/JP6321738B2/ja active Active
- 2016-11-04 ZA ZA2016/07642A patent/ZA201607642B/en unknown
-
2017
- 2017-02-21 US US15/438,330 patent/US20170166960A1/en not_active Abandoned
- 2017-06-28 JP JP2017125772A patent/JP6480511B2/ja active Active
- 2017-11-09 US US15/808,442 patent/US10077467B2/en active Active
-
2018
- 2018-03-07 AU AU2018201671A patent/AU2018201671B2/en active Active
- 2018-08-30 US US16/117,949 patent/US10584376B2/en active Active - Reinstated
-
2020
- 2020-02-05 US US16/782,805 patent/US11208687B2/en active Active
-
2021
- 2021-11-15 US US17/526,638 patent/US11866773B2/en active Active
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UA116205C2 (uk) | Спосіб кількісного визначення послідовності нуклеїнової кислоти в зразку | |
| GB201317477D0 (en) | Methods, compositions and kits for determing the presence/absnece of a variant nucleic acid sequence | |
| WO2012021493A3 (en) | Compositions and methods for quantifying a nucleic acid sequence in a sample | |
| MX353840B (es) | Deteccion de acidos nucleicos. | |
| IL233773B (en) | Methods for identifying a target sequence of a nucleic acid from DNA or a mixture of nucleic acids and a kit for performing these methods | |
| EP3862439A3 (en) | Liver cancer detection kit or device, and detection method | |
| WO2016064894A3 (en) | Compositions and methods for detecting an rna virus | |
| GB201219137D0 (en) | Direct nucleic acid amplification kit, reagent and method | |
| EP3967769A3 (en) | Lung cancer detection kit or device, and detection method | |
| WO2015058008A3 (en) | Enhanced nucleic acid identification and detection | |
| EP3971299A3 (en) | Colorectal cancer detection kit or device, and detection method | |
| EP3757225A3 (en) | Pancreatic cancer detection kit or device, and detection method | |
| AR080009A1 (es) | Alteracion genomica objetivo utilizando nucleasas de dedos de zinc | |
| EP4461824A3 (en) | Detection kit or device and detection method for biliary tract cancer | |
| EP4495266A3 (en) | Esophageal cancer detection kit or device, and detection method | |
| IN2015DN02479A (es) | ||
| MX376755B (es) | Detección de ácidos nucleicos diana mediante el uso de hibridación. | |
| WO2014005125A3 (en) | Fluorescent compounds and uses thereof | |
| MX2013001799A (es) | Metodos para la captura y secuenciacion de acido nucleico | |
| MX2015001961A (es) | Metodos y sistemas para ensayos. | |
| EP3216852A4 (en) | Method for introducing nucleic acid, method for detecting nucleic acid, method for analyzing biological component, array device for biological component assay, and kit for analyzing biological component | |
| ZA201405894B (en) | Detection of nucleotide variation on target nucleic acid sequence by pto cleavage and extension assay | |
| SG11201602686YA (en) | Pcr primer set for bacterial dna amplification, kit for detecting and/or identifying bacterial species, and method for detecting and/or identifying bacterial species | |
| EP2488664A4 (en) | METHOD AND COMPOSITIONS FOR REINFORCING TARGET SEQUENCES FROM NUCLEIC ACID SAMPLES | |
| EP4524262A3 (en) | Compositions and methods for enhancing and/or predicting dna amplification |