UA101478C2 - Соединения, полезные как ингибиторы raf-киназы - Google Patents
Соединения, полезные как ингибиторы raf-киназыInfo
- Publication number
- UA101478C2 UA101478C2 UAA200913589A UAA200913589A UA101478C2 UA 101478 C2 UA101478 C2 UA 101478C2 UA A200913589 A UAA200913589 A UA A200913589A UA A200913589 A UAA200913589 A UA A200913589A UA 101478 C2 UA101478 C2 UA 101478C2
- Authority
- UA
- Ukraine
- Prior art keywords
- inhibitors
- protein kinase
- compounds useful
- raf protein
- raf
- Prior art date
Links
Classifications
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- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US94729107P | 2007-06-29 | 2007-06-29 | |
| PCT/US2008/068762 WO2009006389A2 (en) | 2007-06-29 | 2008-06-30 | Pyrimidine derivatives useful as raf kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA101478C2 true UA101478C2 (ru) | 2013-04-10 |
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ID=40029124
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| TWI444379B (zh) | 2007-06-29 | 2014-07-11 | Sunesis Pharmaceuticals Inc | 有用於作為Raf激酶抑制劑之化合物 |
| JP2012514044A (ja) | 2008-12-30 | 2012-06-21 | ミレニアム ファーマシューティカルズ, インコーポレイテッド | Rafキナーゼ阻害剤として有用なヘテロアリール化合物 |
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