EA201070247A1 - Ингибиторы протеасом - Google Patents

Ингибиторы протеасом

Info

Publication number
EA201070247A1
EA201070247A1 EA201070247A EA201070247A EA201070247A1 EA 201070247 A1 EA201070247 A1 EA 201070247A1 EA 201070247 A EA201070247 A EA 201070247A EA 201070247 A EA201070247 A EA 201070247A EA 201070247 A1 EA201070247 A1 EA 201070247A1
Authority
EA
Eurasian Patent Office
Prior art keywords
present
inhibitors
proteas
proteas inhibitors
compositions
Prior art date
Application number
EA201070247A
Other languages
English (en)
Other versions
EA028622B1 (ru
Inventor
Эдвард Дж. Олхава
Михаела Д. Данка
Original Assignee
Милленниум Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38691782&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201070247(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Милленниум Фармасьютикалз, Инк. filed Critical Милленниум Фармасьютикалз, Инк.
Publication of EA201070247A1 publication Critical patent/EA201070247A1/ru
Publication of EA028622B1 publication Critical patent/EA028622B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

В настоящем изобретении предложены новые соединения, подходящие для применения в качестве ингибиторов протеасом. В настоящем изобретении также предложены фармацевтические композиции, содержащие соединения согласно настоящему изобретению, и способы применения указанных композиций для лечения различных заболеваний.
EA201070247A 2007-08-06 2007-08-06 Ингибиторы протеасом EA028622B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2007/017440 WO2009020448A1 (en) 2007-08-06 2007-08-06 Proteasome inhibitors

Publications (2)

Publication Number Publication Date
EA201070247A1 true EA201070247A1 (ru) 2010-06-30
EA028622B1 EA028622B1 (ru) 2017-12-29

Family

ID=38691782

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070247A EA028622B1 (ru) 2007-08-06 2007-08-06 Ингибиторы протеасом

Country Status (33)

Country Link
EP (3) EP3210987A1 (ru)
JP (1) JP5261488B2 (ru)
KR (6) KR20140042933A (ru)
CN (1) CN101772507B (ru)
AU (1) AU2007357338B2 (ru)
BR (1) BRPI0721905B8 (ru)
CA (1) CA2695082C (ru)
CY (2) CY1113386T1 (ru)
DK (1) DK2178888T3 (ru)
EA (1) EA028622B1 (ru)
EC (1) ECSP10010015A (ru)
ES (1) ES2390606T3 (ru)
FR (1) FR17C1011I2 (ru)
GE (1) GEP20125599B (ru)
HK (2) HK1143595A1 (ru)
HR (1) HRP20120745T1 (ru)
HU (1) HUS1700018I1 (ru)
IL (4) IL203641A (ru)
LT (1) LTC2178888I2 (ru)
LU (1) LUC00013I2 (ru)
MY (1) MY161991A (ru)
NL (1) NL300871I2 (ru)
NZ (1) NZ582693A (ru)
PH (1) PH12014500053B1 (ru)
PL (1) PL2178888T3 (ru)
PT (1) PT2178888E (ru)
RS (1) RS52435B (ru)
SG (1) SG10201508712QA (ru)
SI (1) SI2178888T1 (ru)
TN (1) TN2010000060A1 (ru)
UA (1) UA97536C2 (ru)
WO (1) WO2009020448A1 (ru)
ZA (1) ZA201000348B (ru)

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RU2625801C2 (ru) * 2012-12-03 2017-07-19 Ф. Хоффманн-Ля Рош Аг Соединения замещенной триазолбороновой кислоты

Also Published As

Publication number Publication date
KR20100059811A (ko) 2010-06-04
PH12014500053A1 (en) 2015-03-30
CA2695082A1 (en) 2009-02-12
EP2178888A1 (en) 2010-04-28
CA2695082C (en) 2015-07-28
KR101474831B1 (ko) 2014-12-19
RS52435B (en) 2013-02-28
ES2390606T3 (es) 2012-11-14
JP2010535759A (ja) 2010-11-25
KR101831674B1 (ko) 2018-02-23
BRPI0721905A2 (pt) 2014-02-25
MY161991A (en) 2017-05-31
KR20160040735A (ko) 2016-04-14
IL242291A0 (en) 2015-11-30
JP5261488B2 (ja) 2013-08-14
WO2009020448A1 (en) 2009-02-12
BRPI0721905B1 (pt) 2020-11-17
HK1143595A1 (en) 2011-01-07
BRPI0721905B8 (pt) 2021-05-25
IL242290A0 (en) 2015-11-30
KR20170004031A (ko) 2017-01-10
IL203641A (en) 2015-11-30
GEP20125599B (en) 2012-08-10
HUS1700018I1 (hu) 2017-05-29
KR20140042933A (ko) 2014-04-07
IL242291A (en) 2017-12-31
PL2178888T3 (pl) 2012-11-30
SI2178888T1 (sl) 2012-11-30
NZ582693A (en) 2012-01-12
CN101772507A (zh) 2010-07-07
IL242290A (en) 2017-12-31
EP3210987A1 (en) 2017-08-30
FR17C1011I1 (ru) 2017-05-26
AU2007357338B2 (en) 2014-03-20
TN2010000060A1 (en) 2011-09-26
CN101772507B (zh) 2012-12-12
EA028622B1 (ru) 2017-12-29
PT2178888E (pt) 2012-10-04
DK2178888T3 (da) 2012-10-01
IL242292A0 (en) 2015-11-30
CY2017016I1 (el) 2017-07-12
ZA201000348B (en) 2011-03-30
SG10201508712QA (en) 2015-11-27
FR17C1011I2 (fr) 2018-04-27
EP2527347A1 (en) 2012-11-28
AU2007357338A1 (en) 2009-02-12
HRP20120745T1 (hr) 2012-10-31
CY1113386T1 (el) 2016-06-22
KR20150010802A (ko) 2015-01-28
LUC00013I2 (ru) 2017-06-19
KR20140042932A (ko) 2014-04-07
PH12014500053B1 (en) 2015-03-30
IL242292A (en) 2017-12-31
LTPA2017010I1 (lt) 2017-05-10
CY2017016I2 (el) 2017-07-12
HK1182924A1 (zh) 2013-12-13
ECSP10010015A (es) 2010-04-30
LTC2178888I2 (lt) 2018-03-12
LUC00013I1 (ru) 2017-04-06
EP2178888B1 (en) 2012-07-04
NL300871I2 (nl) 2017-12-07
UA97536C2 (en) 2012-02-27

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