TWI772261B - Pd-l1拮抗劑組合治療 - Google Patents

Pd-l1拮抗劑組合治療 Download PDF

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TWI772261B
TWI772261B TW105118967A TW105118967A TWI772261B TW I772261 B TWI772261 B TW I772261B TW 105118967 A TW105118967 A TW 105118967A TW 105118967 A TW105118967 A TW 105118967A TW I772261 B TWI772261 B TW I772261B
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cancer
antibody
antagonist
administered
dose
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TW105118967A
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TW201709933A (zh
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格倫 伊恩 安德魯斯
士浩 陳
艾莉珊德拉 迪 皮托
大衛 佛塔納
納連娜 高伯格
家揚 林
華 龍
瑪席拉 馬丁吉奧尼
迪米里 瑟吉 安東尼 努坦
亞隆 大衛 泰爾
愛德瑞恩 沃弗森
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德商馬克專利公司
美商輝瑞大藥廠
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    • A61K31/00—Medicinal preparations containing organic active ingredients
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
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    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
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    • C07K2317/00—Immunoglobulins specific features
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  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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TW105118967A 2015-06-16 2016-06-16 Pd-l1拮抗劑組合治療 TWI772261B (zh)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US201562180543P 2015-06-16 2015-06-16
US62/180,543 2015-06-16
US201562219995P 2015-09-17 2015-09-17
US62/219,995 2015-09-17
US201662286501P 2016-01-25 2016-01-25
US62/286,501 2016-01-25
US201662337489P 2016-05-17 2016-05-17
US62/337,489 2016-05-17

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TW201709933A TW201709933A (zh) 2017-03-16
TWI772261B true TWI772261B (zh) 2022-08-01

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US (2) US10869924B2 (https=)
EP (1) EP3310810B1 (https=)
JP (2) JP6876629B2 (https=)
KR (1) KR102712880B1 (https=)
CN (1) CN107750166B (https=)
AU (1) AU2016280003B2 (https=)
CA (1) CA2989586A1 (https=)
IL (1) IL256245B (https=)
MX (1) MX390878B (https=)
MY (1) MY193229A (https=)
PH (1) PH12017501857B1 (https=)
RU (1) RU2766890C2 (https=)
TW (1) TWI772261B (https=)
UA (1) UA126892C2 (https=)
WO (1) WO2016205277A1 (https=)

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