TWI731861B - FcRH5之人源化及親和力成熟抗體及使用方法 - Google Patents

FcRH5之人源化及親和力成熟抗體及使用方法 Download PDF

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TWI731861B
TWI731861B TW105118965A TW105118965A TWI731861B TW I731861 B TWI731861 B TW I731861B TW 105118965 A TW105118965 A TW 105118965A TW 105118965 A TW105118965 A TW 105118965A TW I731861 B TWI731861 B TW I731861B
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amino acid
acid sequence
seq
hvr
fcrh5
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TW105118965A
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Chinese (zh)
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TW201712036A (zh
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伊西得洛 赫尼爾
提姆T 強提拉
李吉
賈斯汀 舍爾
丹尼爾 迪卡拉
迪亞哥 埃勒曼
克里斯托夫 施皮斯
保羅 卡特
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美商建南德克公司
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    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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TW105118965A 2015-06-16 2016-06-16 FcRH5之人源化及親和力成熟抗體及使用方法 TWI731861B (zh)

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TW112144815A TWI876687B (zh) 2015-06-16 2016-06-16 FcRH5之人源化及親和力成熟抗體及使用方法
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EP2904016B1 (en) 2012-10-08 2018-11-14 Roche Glycart AG Fc-free antibodies comprising two fab-fragments and methods of use
EP3444278A1 (en) 2013-02-26 2019-02-20 Roche Glycart AG Bispecific t cell activating antigen binding molecules
KR20180023035A (ko) 2013-02-26 2018-03-06 로슈 글리카트 아게 이중특이적 t 세포 활성화 항원 결합 분자
TWI725931B (zh) 2013-06-24 2021-05-01 美商建南德克公司 抗fcrh5抗體
PE20210107A1 (es) 2013-12-17 2021-01-19 Genentech Inc Anticuerpos anti-cd3 y metodos de uso
DK3177643T3 (da) 2014-08-04 2019-07-15 Hoffmann La Roche Bispecifikke T-celle-aktiverende antigenbindende molekyler
US9751946B2 (en) 2014-09-12 2017-09-05 Genentech, Inc. Anti-CLL-1 antibodies and immunoconjugates
DK3221356T3 (da) 2014-11-20 2020-11-02 Hoffmann La Roche T-celleaktiverende, bispecifikke, antigenbindende molekyler mod folr1 og cd3
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