MX2016000272A - Construcciones de unión a los antígenos cd19 y cd3 biespecificos. - Google Patents

Construcciones de unión a los antígenos cd19 y cd3 biespecificos.

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Publication number
MX2016000272A
MX2016000272A MX2016000272A MX2016000272A MX2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A MX 2016000272 A MX2016000272 A MX 2016000272A
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MX
Mexico
Prior art keywords
contructs
antigen binding
bispecific
antigens
bind
Prior art date
Application number
MX2016000272A
Other languages
English (en)
Inventor
Bhimarao Dixit Surjit
Yiu Kon Ng Gordon
Spreter Von Kreudenstein Thomas
Original Assignee
Zymeworks Inc
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Publication date
Application filed by Zymeworks Inc filed Critical Zymeworks Inc
Publication of MX2016000272A publication Critical patent/MX2016000272A/es

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6849Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872Intracellular protein regulatory factors and their receptors, e.g. including ion channels
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
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Abstract

Se describen construcciones de unión a antígenos biespecíficos, que se unen a antígenos CD3 y CD19 o CD20.
MX2016000272A 2013-07-12 2014-07-11 Construcciones de unión a los antígenos cd19 y cd3 biespecificos. MX2016000272A (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201361845948P 2013-07-12 2013-07-12
US201461927877P 2014-01-15 2014-01-15
US201461978719P 2014-04-11 2014-04-11
PCT/US2014/046436 WO2015006749A2 (en) 2013-07-12 2014-07-11 Bispecific cd3 and cd19 antigen binding contructs

Publications (1)

Publication Number Publication Date
MX2016000272A true MX2016000272A (es) 2016-08-03

Family

ID=52280737

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2016000272A MX2016000272A (es) 2013-07-12 2014-07-11 Construcciones de unión a los antígenos cd19 y cd3 biespecificos.

Country Status (11)

Country Link
US (1) US20160355588A1 (es)
EP (1) EP3019622A4 (es)
JP (1) JP2016531100A (es)
KR (1) KR20160029128A (es)
CN (1) CN105531374A (es)
AU (1) AU2014287011A1 (es)
BR (1) BR112016000666A2 (es)
CA (1) CA2917886A1 (es)
MX (1) MX2016000272A (es)
RU (1) RU2016104130A (es)
WO (1) WO2015006749A2 (es)

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