TWI593735B - 包含酵素之水溶性組合物及其製備方法 - Google Patents
包含酵素之水溶性組合物及其製備方法 Download PDFInfo
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- TWI593735B TWI593735B TW102108343A TW102108343A TWI593735B TW I593735 B TWI593735 B TW I593735B TW 102108343 A TW102108343 A TW 102108343A TW 102108343 A TW102108343 A TW 102108343A TW I593735 B TWI593735 B TW I593735B
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- water
- dehydrogenase
- enzyme
- reductase
- soluble film
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
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- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
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- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/20—Organic compounds containing oxygen
- C11D3/22—Carbohydrates or derivatives thereof
- C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
- C11D3/225—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin etherified, e.g. CMC
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- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/3757—(Co)polymerised carboxylic acids, -anhydrides, -esters in solid and liquid compositions
- C11D3/3761—(Co)polymerised carboxylic acids, -anhydrides, -esters in solid and liquid compositions in solid compositions
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/37—Polymers
- C11D3/3746—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds
- C11D3/378—(Co)polymerised monomers containing sulfur, e.g. sulfonate
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38609—Protease or amylase in solid compositions only
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38627—Preparations containing enzymes, e.g. protease or amylase containing lipase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38636—Preparations containing enzymes, e.g. protease or amylase containing enzymes other than protease, amylase, lipase, cellulase, oxidase or reductase
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
- C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
- C11D3/16—Organic compounds
- C11D3/38—Products with no well-defined composition, e.g. natural products
- C11D3/386—Preparations containing enzymes, e.g. protease or amylase
- C11D3/38645—Preparations containing enzymes, e.g. protease or amylase containing cellulase
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- Dispersion Chemistry (AREA)
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Applications Claiming Priority (1)
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| US13/422,709 US10087401B2 (en) | 2012-03-16 | 2012-03-16 | Water soluble compositions incorporating enzymes, and method of making same |
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| TWI593735B true TWI593735B (zh) | 2017-08-01 |
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| TW (1) | TWI593735B (https=) |
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Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10087401B2 (en) * | 2012-03-16 | 2018-10-02 | Monosol, Llc | Water soluble compositions incorporating enzymes, and method of making same |
| US9394092B2 (en) | 2012-04-16 | 2016-07-19 | Monosol, Llc | Powdered pouch and method of making same |
| AR096270A1 (es) | 2013-05-14 | 2015-12-16 | Novozymes As | Composiciones detergentes |
| WO2015048718A2 (en) | 2013-09-30 | 2015-04-02 | Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center | Inhibition of thymine dna glycosylase in the treatment of cancer |
| CZ307195B6 (cs) | 2013-11-18 | 2018-03-14 | František Trnka | Farmaceutická kompozice obsahující směs proenzymů a enzymů |
| AU2016243825B2 (en) * | 2015-03-27 | 2020-08-20 | Monosol, Llc | Water soluble film, packets employing the film, and methods of making and using same |
| WO2017036915A1 (en) * | 2015-08-28 | 2017-03-09 | Unilever N.V. | Liquid detergency composition comprising protease and non-protease enzyme |
| JP6765191B2 (ja) * | 2016-01-07 | 2020-10-07 | 花王株式会社 | 洗浄剤組成物 |
| PL3483241T3 (pl) * | 2017-11-13 | 2021-03-08 | The Procter & Gamble Company | Kompozycja detergentowa |
| CN108085326B (zh) * | 2018-01-24 | 2021-04-27 | 中国科学院青岛生物能源与过程研究所 | 一种柳枝稷腺苷高半胱氨酸在改变木质素单体和提高细胞壁降解效率方面的应用 |
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| US10858619B2 (en) * | 2018-06-08 | 2020-12-08 | The Procter & Gamble Company | Water-soluble unit dose articles made from extruded films and containing household care compositions and methods for making the same |
| WO2019238761A1 (en) * | 2018-06-15 | 2019-12-19 | Basf Se | Water soluble multilayer films containing wash active chemicals and enzymes |
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| CN116940622A (zh) * | 2021-03-25 | 2023-10-24 | 三菱化学株式会社 | 水溶性薄膜及使用其的药剂包装体以及它们的制造方法 |
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| UY40141A (es) | 2022-02-09 | 2023-08-15 | Pivot Bio Inc | Microbio fijador de nitrógeno formulado en seco y envasado en una película soluble en agua para una |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02124945A (ja) * | 1988-07-27 | 1990-05-14 | Kuraray Co Ltd | 水溶性フイルム |
| JP2006526995A (ja) * | 2003-06-09 | 2006-11-30 | インセンス・リミテッド | 殺菌放射線への曝露時に酵素を安定化させる方法 |
Family Cites Families (153)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3186869A (en) | 1961-02-23 | 1965-06-01 | Friedman Jack | Coated film for laundry package |
| GB1296839A (https=) | 1969-05-29 | 1972-11-22 | ||
| US3576760A (en) * | 1969-06-13 | 1971-04-27 | Nat Patent Dev Corp | Water soluble entrapping |
| NL7103490A (https=) | 1970-03-18 | 1971-09-21 | ||
| GB1372034A (en) | 1970-12-31 | 1974-10-30 | Unilever Ltd | Detergent compositions |
| US3728739A (en) | 1971-02-23 | 1973-04-24 | American Cyanamid Co | Sterile surgical gloves |
| US3762454A (en) | 1971-11-15 | 1973-10-02 | R Wilkins | Disposable garbage container |
| ZA734721B (en) | 1972-07-14 | 1974-03-27 | Procter & Gamble | Detergent compositions |
| JPS516726A (ja) | 1974-07-08 | 1976-01-20 | Hitachi Ltd | Insatsuhoho |
| US4115922A (en) | 1976-09-20 | 1978-09-26 | Alderman C Gale | Dental crown and bridge shading system |
| US4115292A (en) | 1977-04-20 | 1978-09-19 | The Procter & Gamble Company | Enzyme-containing detergent articles |
| US4176079A (en) | 1977-04-20 | 1979-11-27 | The Procter & Gamble Company | Water-soluble enzyme-containing article |
| EP0006268B2 (en) | 1978-06-20 | 1988-08-24 | THE PROCTER & GAMBLE COMPANY | Washing and softening compositions and processes for making them |
| EP0011340B1 (en) | 1978-11-20 | 1982-11-24 | THE PROCTER & GAMBLE COMPANY | Detergent composition having textile softening properties |
| DK187280A (da) | 1980-04-30 | 1981-10-31 | Novo Industri As | Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode |
| LU83765A1 (fr) | 1981-11-17 | 1983-09-01 | Oreal | Composition cosmetique sous forme aqueuse ou anydre contenant une phase grasse a base de graisse de shorea |
| US5310675A (en) | 1983-06-24 | 1994-05-10 | Genencor, Inc. | Procaryotic carbonyl hydrolases |
| US4760025A (en) | 1984-05-29 | 1988-07-26 | Genencor, Inc. | Modified enzymes and methods for making same |
| US5352594A (en) | 1984-05-29 | 1994-10-04 | Genecor, Inc. | Selection and method of making enzymes for perhydrolysis system and for altering substrate specificity, specific activity and catalytic efficiency |
| US5244791A (en) | 1984-05-29 | 1993-09-14 | Genecor International, Inc. | Methods of ester hydrolysis |
| US5204015A (en) | 1984-05-29 | 1993-04-20 | Genencor International, Inc. | Subtilisin mutants |
| US5264366A (en) | 1984-05-29 | 1993-11-23 | Genencor, Inc. | Protease deficient bacillus |
| US5371008A (en) | 1984-05-29 | 1994-12-06 | Genencor International, Inc. | Substrate assisted catalysis |
| US5801038A (en) | 1984-05-29 | 1998-09-01 | Genencor International Inc. | Modified subtilisins having amino acid alterations |
| US5346823A (en) | 1984-05-29 | 1994-09-13 | Genencor, Inc. | Subtilisin modifications to enhance oxidative stability |
| US5155033A (en) | 1989-01-06 | 1992-10-13 | Genencor, Inc. | Subtilisins modified at position 225 resulting in a shift in catalytic activity |
| US5411873A (en) | 1984-05-29 | 1995-05-02 | Genencor, Inc. | Process for producing heterologous polypeptides |
| US5182204A (en) | 1984-05-29 | 1993-01-26 | Genencor International, Inc. | Non-human carbonyl hydrolase mutants, vectors encoding same and hosts transformed with said vectors |
| US5185258A (en) | 1984-05-29 | 1993-02-09 | Genencor International, Inc. | Subtilisin mutants |
| US5972682A (en) | 1984-05-29 | 1999-10-26 | Genencor International, Inc. | Enzymatically active modified subtilisins |
| US5371190A (en) | 1984-05-29 | 1994-12-06 | Genencor International, Inc. | Substrate assisted catalysis |
| US4664064A (en) | 1985-03-21 | 1987-05-12 | Lowe H Edward | Cat box filler with incorporated pesticide |
| JPH0697997B2 (ja) | 1985-08-09 | 1994-12-07 | ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ | 新規の酵素的洗浄剤添加物 |
| US4749653A (en) | 1985-10-21 | 1988-06-07 | Owens-Corning Fiberglas Corporation | Enzyme immobilization on non-porous glass fibers |
| US5766912A (en) | 1986-03-17 | 1998-06-16 | Novo Nordisk A/S | Humicola lipase produced in aspergillus |
| US5874558A (en) | 1986-03-17 | 1999-02-23 | Novo Nordisk | Nucleic acid encoding a recombinant humicola sp. lipase |
| US5536661A (en) | 1987-03-10 | 1996-07-16 | Novo Nordisk A/S | Process for the production of protein products in aspergillus |
| US5145842A (en) | 1986-06-11 | 1992-09-08 | Alder Research Center Limited Partnership | Protein kinase c. modulators. d. |
| ATE110768T1 (de) | 1986-08-29 | 1994-09-15 | Novo Nordisk As | Enzymhaltiger reinigungsmittelzusatz. |
| NZ221627A (en) | 1986-09-09 | 1993-04-28 | Genencor Inc | Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios |
| JP2533763B2 (ja) | 1986-10-27 | 1996-09-11 | 忠生 白石 | フィルム状成分を含有する入浴剤 |
| DE3854249T2 (de) | 1987-08-28 | 1996-02-29 | Novonordisk As | Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen. |
| JPS6474992A (en) | 1987-09-16 | 1989-03-20 | Fuji Oil Co Ltd | Dna sequence, plasmid and production of lipase |
| US5288627A (en) | 1988-01-07 | 1994-02-22 | Novo Nordisk A/S | Endoprotease from Fusarium oxysporumDSM 2672 for use in detergents |
| EP0471265B1 (en) | 1988-01-07 | 1995-10-25 | Novo Nordisk A/S | Specific protease |
| DK6488D0 (da) | 1988-01-07 | 1988-01-07 | Novo Industri As | Enzymer |
| JP3079276B2 (ja) | 1988-02-28 | 2000-08-21 | 天野製薬株式会社 | 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法 |
| WO1989009259A1 (en) | 1988-03-24 | 1989-10-05 | Novo-Nordisk A/S | A cellulase preparation |
| US5776757A (en) | 1988-03-24 | 1998-07-07 | Novo Nordisk A/S | Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof |
| DE68928038T3 (de) | 1988-03-25 | 2002-09-12 | Genencor International, Inc. | Molekulare Klonierung und Expression von Genen, die für lipolytische Enzyme kodieren |
| JPH0249036A (ja) | 1988-04-08 | 1990-02-19 | Asahi Chem Ind Co Ltd | ダステイング処理剤並びにダステイング処理した熱可塑性樹脂フイルム及びそのフイルムのダステイング処理方法 |
| CA2009047C (en) | 1989-02-27 | 1999-06-08 | Daniel Wayne Michael | Microcapsules containing hydrophobic liquid core |
| US5002789A (en) | 1989-04-17 | 1991-03-26 | The Pillsbury Company | Food colorant system |
| US5658871A (en) | 1989-07-07 | 1997-08-19 | Lever Brothers Company, Division Of Conopco, Inc. | Microbial lipase muteins and detergent compositions comprising same |
| GB8915658D0 (en) | 1989-07-07 | 1989-08-23 | Unilever Plc | Enzymes,their production and use |
| EP0528828B2 (de) | 1990-04-14 | 1997-12-03 | Genencor International GmbH | Alkalische bacillus-lipasen, hierfür codierende dna-sequenzen sowie bacilli, die diese lipasen produzieren |
| US20010036910A1 (en) | 1990-05-09 | 2001-11-01 | Grethe Rasmussen | Cellulase preparation comprising an endoglucanase enzyme |
| DK115890D0 (da) | 1990-05-09 | 1990-05-09 | Novo Nordisk As | Enzym |
| CA2082279C (en) | 1990-05-09 | 2007-09-04 | Grethe Rasmussen | Cellulase preparation comprising an endoglucanase enzyme |
| NZ238385A (en) | 1990-07-03 | 1993-05-26 | Ecolab Inc | A detersive system in a water soluble film package |
| US5869438A (en) | 1990-09-13 | 1999-02-09 | Novo Nordisk A/S | Lipase variants |
| DE69129988T2 (de) | 1990-09-13 | 1999-03-18 | Novo Nordisk A/S, Bagsvaerd | Lipase-varianten |
| US5892013A (en) | 1990-09-13 | 1999-04-06 | Novo Nordisk A/S | Lipase variants |
| US5520838A (en) | 1991-01-16 | 1996-05-28 | The Procter & Gamble Company | Compact detergent compositions with high activity cellulase |
| US5443750A (en) | 1991-01-16 | 1995-08-22 | The Procter & Gamble Company | Detergent compositions with high activity cellulase and softening clays |
| DE69133035T2 (de) | 1991-01-16 | 2003-02-13 | The Procter & Gamble Company, Cincinnati | Kompakte Waschmittelzusammensetzungen mit hochaktiven Cellulasen |
| KR100258460B1 (ko) | 1991-05-01 | 2000-06-01 | 한센 핀 베네드 | 안정화 효소 및 세제 조성물 |
| US5232612A (en) | 1991-08-28 | 1993-08-03 | The Procter & Gamble Company | Solid, particulate fabric softener with protected, dryer-activated, cyclodextrin/perfume complex |
| US5668073A (en) | 1991-11-06 | 1997-09-16 | The Procter & Gamble Company | Detergent compounds with high activity cellulase and quaternary ammonium compounds |
| DK88892D0 (da) | 1992-07-06 | 1992-07-06 | Novo Nordisk As | Forbindelse |
| EP0651794B1 (en) | 1992-07-23 | 2009-09-30 | Novozymes A/S | MUTANT $g(a)-AMYLASE, DETERGENT AND DISH WASHING AGENT |
| EP1431389A3 (en) | 1992-10-06 | 2004-06-30 | Novozymes A/S | Cellulase variants |
| HU221308B1 (en) | 1992-10-26 | 2002-09-28 | Sanol Arznei Schwarz Gmbh | Process for producing microcapsules |
| CZ293163B6 (cs) | 1993-02-11 | 2004-02-18 | Genencor International, Inc. | Mutanta alfa-amylázy, její použití, kódová DNA pro tuto mutantu, vektor pro expresi, hostitelské buňky, čisticí prostředek a prostředek pro zkapalnění škrobu |
| ATE287946T1 (de) | 1993-04-27 | 2005-02-15 | Genencor Int | Neuartige lipasevarianten zur verwendung in reinigungsmitteln |
| DK52393D0 (https=) | 1993-05-05 | 1993-05-05 | Novo Nordisk As | |
| JP2859520B2 (ja) | 1993-08-30 | 1999-02-17 | ノボ ノルディスク アクティーゼルスカブ | リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物 |
| JPH07143883A (ja) | 1993-11-24 | 1995-06-06 | Showa Denko Kk | リパーゼ遺伝子及び変異体リパーゼ |
| EP0746618B1 (en) | 1994-02-22 | 2002-08-21 | Novozymes A/S | A method of preparing a variant of a lipolytic enzyme |
| US6117664A (en) | 1994-03-03 | 2000-09-12 | Novo Nordisk A/S | Alkaline cellulases |
| WO1995024471A1 (en) | 1994-03-08 | 1995-09-14 | Novo Nordisk A/S | Novel alkaline cellulases |
| JP3851656B2 (ja) | 1994-05-04 | 2006-11-29 | ジェネンコア インターナショナル インコーポレーテッド | 改善された界面活性剤耐性を有するリパーゼ |
| WO1995035381A1 (en) | 1994-06-20 | 1995-12-28 | Unilever N.V. | Modified pseudomonas lipases and their use |
| WO1996000292A1 (en) | 1994-06-23 | 1996-01-04 | Unilever N.V. | Modified pseudomonas lipases and their use |
| DE69535733T2 (de) | 1994-10-06 | 2009-04-23 | Novozymes A/S | Ein enzympräparat mit endoglucanase aktivität |
| BE1008998A3 (fr) | 1994-10-14 | 1996-10-01 | Solvay | Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci. |
| BR9509525A (pt) | 1994-10-26 | 1995-10-26 | Novo Nordisk As | Construção de dna vetor de expressão recombinante célula processo para produzir a enzima que exibe atividade lipolítica enzima que exibe atividade lipolítica preparação de enzima aditivo de detergente e composição de detergente |
| US6093562A (en) | 1996-02-05 | 2000-07-25 | Novo Nordisk A/S | Amylase variants |
| AR000862A1 (es) | 1995-02-03 | 1997-08-06 | Novozymes As | Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del |
| JPH08228778A (ja) | 1995-02-27 | 1996-09-10 | Showa Denko Kk | 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法 |
| EP0815209B2 (en) | 1995-03-17 | 2015-02-25 | Novozymes A/S | Novel endoglucanases |
| WO1997007202A1 (en) | 1995-08-11 | 1997-02-27 | Novo Nordisk A/S | Novel lipolytic enzymes |
| AU6414196A (en) | 1995-07-14 | 1997-02-18 | Novo Nordisk A/S | A modified enzyme with lipolytic activity |
| JPH09150407A (ja) | 1995-11-30 | 1997-06-10 | Oji Paper Co Ltd | 芳香性古紙ボード |
| BR9510680A (pt) | 1995-12-29 | 1999-03-30 | Procter & Gamble | Composições detergentes compreendendo enzimas imobilizadas |
| US5763385A (en) | 1996-05-14 | 1998-06-09 | Genencor International, Inc. | Modified α-amylases having altered calcium binding properties |
| AU3938997A (en) | 1996-08-26 | 1998-03-19 | Novo Nordisk A/S | A novel endoglucanase |
| BR9711479B1 (pt) | 1996-09-17 | 2009-08-11 | variante de celulase tendo uma resistência aumentada a tensìdeo de ánion. | |
| US6300116B1 (en) | 1996-11-04 | 2001-10-09 | Novozymes A/S | Modified protease having improved autoproteolytic stability |
| BR9712473B1 (pt) | 1996-11-04 | 2009-08-11 | variantes de subtilase e composições. | |
| WO1998034946A1 (en) | 1997-02-12 | 1998-08-13 | Massachusetts Institute Of Technology | Daxx, a novel fas-binding protein that activates jnk and apoptosis |
| US6136776A (en) | 1997-04-01 | 2000-10-24 | Dickler Chemical Laboratories, Inc. | Germicidal detergent packet |
| US6037319A (en) | 1997-04-01 | 2000-03-14 | Dickler Chemical Laboratories, Inc. | Water-soluble packets containing liquid cleaning concentrates |
| AU7908898A (en) | 1997-07-04 | 1999-01-25 | Novo Nordisk A/S | Family 6 endo-1,4-beta-glucanase variants and cleaning composit ions containing them |
| EP0896998A1 (en) * | 1997-08-14 | 1999-02-17 | The Procter & Gamble Company | Laundry detergent compositions comprising a saccharide gum degrading enzyme |
| CA2329331C (en) | 1998-04-23 | 2005-06-14 | The Procter & Gamble Company | Encapsulated perfume particles and detergent compositions containing said particles |
| JP2002529398A (ja) | 1998-11-11 | 2002-09-10 | バイオプログレス・テクノロジー・インターナショナル・インコーポレイテッド | 薬剤配達系のためのカプセル |
| US6552024B1 (en) | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
| US6939702B1 (en) | 1999-03-31 | 2005-09-06 | Novozymes A/S | Lipase variant |
| JP2001162708A (ja) | 1999-09-30 | 2001-06-19 | Kao Corp | フィルム |
| US6485736B1 (en) | 2000-09-07 | 2002-11-26 | Syngenta Ltd. | Variable release microcapsules |
| GB0023713D0 (en) | 2000-09-27 | 2000-11-08 | Unilever Plc | A water soluble package |
| DE10053329A1 (de) | 2000-10-27 | 2002-05-08 | Henkel Kgaa | Enzymhaltige Umhüllung für Waschmittel-, Spülmittel- oder Reinigungsmittel-Portionen |
| US6844302B1 (en) | 2000-10-27 | 2005-01-18 | International Flavors & Fragrances Inc. | Encapsulated flavor and fragrance |
| EP1256623A1 (en) | 2001-05-08 | 2002-11-13 | The Procter & Gamble Company | Kit of water-soluble or water dispersible pouches |
| EP1436376B1 (en) | 2001-10-09 | 2010-04-21 | Arrow Coated Products Limited | Method of manufacturing of embedded water-soluble film system |
| US7666337B2 (en) | 2002-04-11 | 2010-02-23 | Monosol Rx, Llc | Polyethylene oxide-based films and drug delivery systems made therefrom |
| US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
| WO2003041667A2 (en) | 2001-11-13 | 2003-05-22 | The Procter & Gamble Company | Compositions containing enzymes stabilized with certain osmo-protectants and methods for using such compositions in personal care |
| ES2231428T3 (es) | 2001-11-23 | 2005-05-16 | THE PROCTER & GAMBLE COMPANY | Bolsa hidrosoluble. |
| EP1314652B1 (en) | 2001-11-23 | 2006-03-08 | The Procter & Gamble Company | Water-soluble pouch |
| JP4226846B2 (ja) | 2002-06-07 | 2009-02-18 | キャタレント・ジャパン株式会社 | 口腔内で崩壊可能なソフトカプセル剤 |
| US20050187137A1 (en) * | 2002-08-14 | 2005-08-25 | Ulrich Pegelow | Portioned cleaning agents or detergents containing phosphate |
| US20040120991A1 (en) * | 2002-09-07 | 2004-06-24 | Mars Incorporated | Edible films having distinct regions |
| EP1560569A4 (en) | 2002-10-11 | 2006-03-22 | Depomed Dev Ltd | GASTRORETENTIVE LEVODOPA DELIVERY FORM |
| JP4056859B2 (ja) | 2002-11-11 | 2008-03-05 | 日本合成化学工業株式会社 | 水溶性フィルム |
| US7977288B2 (en) | 2005-01-12 | 2011-07-12 | Amcol International Corporation | Compositions containing cationically surface-modified microparticulate carrier for benefit agents |
| US7871972B2 (en) | 2005-01-12 | 2011-01-18 | Amcol International Corporation | Compositions containing benefit agents pre-emulsified using colloidal cationic particles |
| EP1844091B2 (en) | 2005-01-22 | 2015-10-07 | The Procter and Gamble Company | Water-soluble film with resistance to solubility prior to being immersed in water |
| EP1863635A2 (en) | 2005-03-24 | 2007-12-12 | Arrow Coated Products Limited | Combined multi-layered water soluble film and process for producing the same |
| ATE481444T1 (de) | 2005-05-13 | 2010-10-15 | Procter & Gamble | Funktionalisierte folien |
| WO2006124483A1 (en) | 2005-05-13 | 2006-11-23 | The Procter & Gamble Company | Bleaching product |
| US20060275567A1 (en) | 2005-06-07 | 2006-12-07 | Richard Vicari | Borate resistant films |
| KR100745365B1 (ko) | 2005-12-09 | 2007-08-02 | 주식회사 엘지생활건강 | 수용성 필름 타입 세정제 |
| US8187854B2 (en) | 2006-01-23 | 2012-05-29 | Novozymes A/S | Lipase variants |
| US20070264487A1 (en) * | 2006-05-12 | 2007-11-15 | Dean Georgiades | Treated film strips |
| US20080176985A1 (en) | 2006-11-13 | 2008-07-24 | Verrall Andrew P | Water-soluble film |
| US7908992B2 (en) | 2007-01-09 | 2011-03-22 | R.P. Scherer Technologies, Llc | System and method for dusting soft capsules |
| US20080234165A1 (en) | 2007-03-20 | 2008-09-25 | Rajan Keshav Panandiker | Liquid laundry detergent compositions comprising performance boosters |
| CN101675160A (zh) | 2007-04-30 | 2010-03-17 | 丹尼斯科美国公司 | 蛋白质水解产物稳定金属蛋白酶洗涤剂制剂的用途 |
| TW200914249A (en) | 2007-09-21 | 2009-04-01 | Taiwan Central Science Biolog Technology Co Ltd | One-time high pressure formation method for aroma cleaning bag |
| US20090209447A1 (en) | 2008-02-15 | 2009-08-20 | Michelle Meek | Cleaning compositions |
| AR070490A1 (es) | 2008-02-29 | 2010-04-07 | Novozymes As | Polipeptidos de thermomyces lanuginosus con actividad de lipasa y polinucleotidos que los codifican |
| ATE539141T1 (de) | 2008-06-13 | 2012-01-15 | Procter & Gamble | Beutel mit mehreren kammern |
| US20110305768A1 (en) * | 2008-07-01 | 2011-12-15 | The Johns Hopkins University | Quick-dissolving oral thin film for targeted delivery of therapeutic agents |
| US8834865B2 (en) * | 2008-11-03 | 2014-09-16 | Danisco Us Inc. | Delivery system for co-formulated enzyme and substrate |
| EP2258820B1 (en) | 2009-06-02 | 2019-12-18 | The Procter and Gamble Company | Water-soluble pouch |
| CN102482404B (zh) | 2009-09-03 | 2014-06-25 | Co2斯塔奇私人有限公司 | 聚合物/热塑性淀粉组合物 |
| ES2527679T5 (es) | 2010-06-24 | 2022-04-19 | Procter & Gamble | Artículos solubles de dosis unitaria que comprenden un polímero catiónico |
| ES2394066T3 (es) * | 2010-06-24 | 2013-01-16 | The Procter & Gamble Company | Composiciones estables que comprenden polímero de celulosa catiónica y celulasa |
| TWM401635U (en) | 2010-11-01 | 2011-04-11 | Hsin-Wei Yu | Assembly type dehumidifying fragrant bag set and dehumidifying fragrant bag |
| US10087401B2 (en) | 2012-03-16 | 2018-10-02 | Monosol, Llc | Water soluble compositions incorporating enzymes, and method of making same |
| US9394092B2 (en) | 2012-04-16 | 2016-07-19 | Monosol, Llc | Powdered pouch and method of making same |
-
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02124945A (ja) * | 1988-07-27 | 1990-05-14 | Kuraray Co Ltd | 水溶性フイルム |
| JP2006526995A (ja) * | 2003-06-09 | 2006-11-30 | インセンス・リミテッド | 殺菌放射線への曝露時に酵素を安定化させる方法 |
Also Published As
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|---|---|
| CN104169411A (zh) | 2014-11-26 |
| WO2013138288A1 (en) | 2013-09-19 |
| TW201339230A (zh) | 2013-10-01 |
| HK1199738A1 (en) | 2015-07-17 |
| MX358067B (es) | 2018-08-03 |
| JP6648079B2 (ja) | 2020-02-14 |
| JP2017210624A (ja) | 2017-11-30 |
| AR091320A1 (es) | 2015-01-28 |
| ES2671043T3 (es) | 2018-06-04 |
| HK1202308A1 (en) | 2015-10-30 |
| AU2013232333B2 (en) | 2017-01-19 |
| CA2866318A1 (en) | 2013-09-19 |
| CN104169411B (zh) | 2019-01-22 |
| JP6431474B2 (ja) | 2018-11-28 |
| EP2825624B1 (en) | 2018-04-25 |
| KR20140138955A (ko) | 2014-12-04 |
| EP3354716A1 (en) | 2018-08-01 |
| EP2825624B2 (en) | 2022-07-27 |
| US20130244920A1 (en) | 2013-09-19 |
| HUE037374T2 (hu) | 2018-08-28 |
| AU2017202549A1 (en) | 2017-05-11 |
| JP2015510028A (ja) | 2015-04-02 |
| AU2013232333A1 (en) | 2014-09-25 |
| MX2014011087A (es) | 2014-10-14 |
| EP2825624A1 (en) | 2015-01-21 |
| AU2017202549B2 (en) | 2018-11-29 |
| US10087401B2 (en) | 2018-10-02 |
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