TWI365190B - Glucopyranosyl derivatives and method for making same - Google Patents

Glucopyranosyl derivatives and method for making same

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Publication number
TWI365190B
TWI365190B TW093122859A TW93122859A TWI365190B TW I365190 B TWI365190 B TW I365190B TW 093122859 A TW093122859 A TW 093122859A TW 93122859 A TW93122859 A TW 93122859A TW I365190 B TWI365190 B TW I365190B
Authority
TW
Taiwan
Prior art keywords
making same
glucopyranosyl derivatives
glucopyranosyl
derivatives
making
Prior art date
Application number
TW093122859A
Other languages
English (en)
Chinese (zh)
Other versions
TW200510441A (en
Inventor
Sumihiro Nomura
Eiji Kawanishi
Kiichiro Ueta
Original Assignee
Mitsubishi Tanabe Pharma Corp
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Publication date
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Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Publication of TW200510441A publication Critical patent/TW200510441A/zh
Application granted granted Critical
Publication of TWI365190B publication Critical patent/TWI365190B/zh

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    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
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    • C07D405/10—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
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    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals

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  • Obesity (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
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TW093122859A 2003-08-01 2004-07-30 Glucopyranosyl derivatives and method for making same TWI365190B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US49153403P 2003-08-01 2003-08-01

Publications (2)

Publication Number Publication Date
TW200510441A TW200510441A (en) 2005-03-16
TWI365190B true TWI365190B (en) 2012-06-01

Family

ID=34115515

Family Applications (2)

Application Number Title Priority Date Filing Date
TW093122859A TWI365190B (en) 2003-08-01 2004-07-30 Glucopyranosyl derivatives and method for making same
TW099122097A TWI385177B (zh) 2003-08-01 2004-07-30 吡喃葡萄糖基衍生物及其製造方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
TW099122097A TWI385177B (zh) 2003-08-01 2004-07-30 吡喃葡萄糖基衍生物及其製造方法

Country Status (36)

Country Link
US (3) US7943788B2 (enExample)
EP (4) EP2896397B2 (enExample)
JP (2) JP4130466B2 (enExample)
KR (2) KR100942622B1 (enExample)
CN (4) CN104109155A (enExample)
AR (1) AR045173A1 (enExample)
AU (1) AU2004260761B2 (enExample)
BE (1) BE2014C027I2 (enExample)
BR (1) BRPI0413232B8 (enExample)
CA (1) CA2534024C (enExample)
CR (2) CR8188A (enExample)
CY (3) CY1113813T1 (enExample)
DK (2) DK2896397T4 (enExample)
EA (2) EA015104B1 (enExample)
ES (4) ES2402098T5 (enExample)
FR (1) FR14C0034I2 (enExample)
HR (2) HRP20130124T4 (enExample)
HU (2) HUE037320T2 (enExample)
IL (2) IL173050A (enExample)
LT (2) LT2896397T (enExample)
LU (1) LU92426I2 (enExample)
ME (1) ME00411B (enExample)
MX (1) MXPA06001274A (enExample)
MY (1) MY143203A (enExample)
NL (1) NL300670I2 (enExample)
NO (4) NO333933B1 (enExample)
NZ (2) NZ545304A (enExample)
PL (2) PL2896397T5 (enExample)
PT (2) PT2896397T (enExample)
RS (1) RS53365B (enExample)
SG (1) SG145694A1 (enExample)
SI (2) SI1651658T2 (enExample)
TW (2) TWI365190B (enExample)
UA (1) UA83243C2 (enExample)
WO (1) WO2005012326A1 (enExample)
ZA (5) ZA200601685B (enExample)

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CN1020944C (zh) * 1990-01-30 1993-05-26 阿图尔-费希尔股份公司费希尔厂 紧固件
ATE510834T1 (de) 2003-03-14 2011-06-15 Astellas Pharma Inc C-glykosid-derivate zur behandlung von diabetes
CN104109155A (zh) † 2003-08-01 2014-10-22 田边三菱制药株式会社 新颖化合物
AU2005219779B2 (en) * 2004-03-04 2011-04-14 Kissei Pharmaceutical Co., Ltd. Fused heterocycle derivative, medicinal composition containing the same, and medicinal use thereof
EA011158B1 (ru) 2004-03-16 2009-02-27 Бёрингер Ингельхайм Интернациональ Гмбх Замещённые глюкопиранозилом бензольные производные, содержащие эти соединения лекарственные средства, их применение и способ их получения
US7393836B2 (en) 2004-07-06 2008-07-01 Boehringer Ingelheim International Gmbh D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
WO2006010557A1 (de) * 2004-07-27 2006-02-02 Boehringer Ingelheim International Gmbh D-glucopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
CA2581922A1 (en) * 2004-09-29 2006-04-06 Kissei Pharmaceutical Co., Ltd. 1-(.beta.-d-glycopyranosyl)-3-substituted nitrogenous heterocyclic compound, medicinal composition containing the same, and medicinal use thereof
JP2008524162A (ja) 2004-12-16 2008-07-10 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルコピラノシル置換ベンゼン誘導体、該化合物を含む薬物、その使用及びその製造方法
TW200637869A (en) 2005-01-28 2006-11-01 Chugai Pharmaceutical Co Ltd The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
TWI365186B (en) * 2005-01-31 2012-06-01 Mitsubishi Tanabe Pharma Corp Indole derivatives
JP4496174B2 (ja) * 2005-01-31 2010-07-07 田辺三菱製薬株式会社 医薬組成物
AR053329A1 (es) * 2005-01-31 2007-05-02 Tanabe Seiyaku Co Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
JP5264183B2 (ja) 2005-02-23 2013-08-14 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング グルコピラノシル置換（（ヘテロ）アリールエチニル−ベンジル）−ベンゼン誘導体及びナトリウム依存性グルコース共輸送体２（ｓｇｌｔ２）インヒビターとしてのそれらの使用
WO2006108842A1 (en) 2005-04-15 2006-10-19 Boehringer Ingelheim International Gmbh Glucopyranosyl-substituted (heteroaryloxy-benzyl)-benzene derivatives as sglt inhibitors
US7723309B2 (en) 2005-05-03 2010-05-25 Boehringer Ingelheim International Gmbh Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
UA91546C2 (uk) 2005-05-03 2010-08-10 Бьорінгер Інгельхайм Інтернаціональ Гмбх КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
US7772191B2 (en) 2005-05-10 2010-08-10 Boehringer Ingelheim International Gmbh Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
TW200726755A (en) * 2005-07-07 2007-07-16 Astellas Pharma Inc A crystalline choline salt of an azulene derivative
EP1910390B1 (en) 2005-07-27 2010-05-19 Boehringer Ingelheim International GmbH Glucopyranosyl-substituted ((hetero)cycloalyklethynyl-benzyl)-benzene derivatives and use thereof as sodium-dependent glucose cotransporter (sglt) inhibitors
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KR100778988B1 (ko) 2007-11-28
ZA200603881B (en) 2010-01-27
CR8188A (es) 2006-07-14
IL206831A0 (en) 2011-08-01
ES2649737T3 (es) 2018-01-15
UA83243C2 (ru) 2008-06-25
DK2896397T3 (da) 2017-11-06
ZA200603879B (en) 2010-01-27
EA010299B1 (ru) 2008-08-29
HUS1400021I1 (hu) 2016-08-29
EA015104B1 (ru) 2011-06-30
JP2007518683A (ja) 2007-07-12
SI1651658T1 (sl) 2013-04-30
NO20060220L (no) 2006-05-02
EP2514756A1 (en) 2012-10-24
BE2014C027I2 (enExample) 2023-12-14
CN103214471B (zh) 2018-02-06
ES2649737T5 (es) 2021-07-07
TWI385177B (zh) 2013-02-11
JP4130466B2 (ja) 2008-08-06
BRPI0413232A (pt) 2006-10-03
FR14C0034I1 (enExample) 2014-06-13
SI1651658T2 (sl) 2020-12-31
NO2026023I1 (no) 2026-04-24
RS20060079A (sr) 2008-04-04
NO334706B1 (no) 2014-05-12
NO20120585L (no) 2006-05-02
BRPI0413232B1 (pt) 2018-03-06
SI2896397T2 (sl) 2020-12-31
PL1651658T3 (pl) 2013-05-31
MY143203A (en) 2011-03-31
SI2896397T1 (en) 2018-01-31
LU92426I9 (enExample) 2019-01-16
CY2014016I1 (el) 2015-12-09
NL300670I2 (enExample) 2016-09-22
ES2531660T3 (es) 2015-03-18
AR045173A1 (es) 2005-10-19
EP3251679A1 (en) 2017-12-06
PL2896397T5 (pl) 2023-06-19
PT2896397T (pt) 2017-11-23

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