TW200902520A - Novel peptide inhibitors of hepatitis C virus replication - Google Patents
Novel peptide inhibitors of hepatitis C virus replication Download PDFInfo
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- TW200902520A TW200902520A TW097117301A TW97117301A TW200902520A TW 200902520 A TW200902520 A TW 200902520A TW 097117301 A TW097117301 A TW 097117301A TW 97117301 A TW97117301 A TW 97117301A TW 200902520 A TW200902520 A TW 200902520A
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
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| MX (1) | MX2009012093A (enExample) |
| NI (1) | NI200900205A (enExample) |
| TN (1) | TN2009000481A1 (enExample) |
| TW (1) | TW200902520A (enExample) |
| WO (1) | WO2008141227A1 (enExample) |
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| MY140680A (en) | 2002-05-20 | 2010-01-15 | Bristol Myers Squibb Co | Hepatitis c virus inhibitors |
| US7491794B2 (en) * | 2003-10-14 | 2009-02-17 | Intermune, Inc. | Macrocyclic compounds as inhibitors of viral replication |
| NZ565059A (en) * | 2005-07-25 | 2011-08-26 | Intermune Inc | Novel macrocyclic inhibitors of hepatitus C virus replication |
| BRPI0617274A2 (pt) * | 2005-10-11 | 2011-07-19 | Intermune Inc | compostos e métodos para a inibição de replicação viral de hepatite c |
| AU2008251425A1 (en) | 2007-05-10 | 2008-11-20 | Array Biopharma, Inc. | Novel peptide inhibitors of hepatitis C virus replication |
| CA2720729A1 (en) | 2008-04-15 | 2009-11-26 | Intermune, Inc. | Novel macrocyclic inhibitors of hepatitis c virus replication |
| US8163921B2 (en) * | 2008-04-16 | 2012-04-24 | Bristol-Myers Squibb Company | Hepatitis C virus inhibitors |
| US20090285774A1 (en) * | 2008-05-15 | 2009-11-19 | Bristol-Myers Squibb Company | Hepatitis C Virus Inhibitors |
| US8207341B2 (en) | 2008-09-04 | 2012-06-26 | Bristol-Myers Squibb Company | Process or synthesizing substituted isoquinolines |
| UY32099A (es) | 2008-09-11 | 2010-04-30 | Enanta Pharm Inc | Inhibidores macrocíclicos de serina proteasas de hepatitis c |
| EP2358736A1 (en) * | 2008-10-15 | 2011-08-24 | Intermune, Inc. | Therapeutic antiviral peptides |
| AR075584A1 (es) | 2009-02-27 | 2011-04-20 | Intermune Inc | COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO. |
| WO2010118078A1 (en) | 2009-04-08 | 2010-10-14 | Idenix Pharmaceuticals, Inc. | Macrocyclic serine protease inhibitors |
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-
2008
- 2008-05-09 AU AU2008251425A patent/AU2008251425A1/en not_active Abandoned
- 2008-05-09 EA EA200971041A patent/EA200971041A1/ru unknown
- 2008-05-09 TW TW097117301A patent/TW200902520A/zh unknown
- 2008-05-09 CA CA002686546A patent/CA2686546A1/en not_active Abandoned
- 2008-05-09 KR KR1020097025827A patent/KR20100027134A/ko not_active Withdrawn
- 2008-05-09 BR BRPI0811447-1A2A patent/BRPI0811447A2/pt not_active IP Right Cessation
- 2008-05-09 JP JP2010507704A patent/JP2010526834A/ja active Pending
- 2008-05-09 EP EP08769417A patent/EP2185524A1/en not_active Withdrawn
- 2008-05-09 AR ARP080101992A patent/AR066528A1/es unknown
- 2008-05-09 US US12/118,624 patent/US7932277B2/en not_active Expired - Fee Related
- 2008-05-09 AP AP2009005057A patent/AP2009005057A0/en unknown
- 2008-05-09 MX MX2009012093A patent/MX2009012093A/es not_active Application Discontinuation
- 2008-05-09 CN CN200880018991A patent/CN101679277A/zh active Pending
- 2008-05-09 CL CL2008001381A patent/CL2008001381A1/es unknown
- 2008-05-09 WO PCT/US2008/063304 patent/WO2008141227A1/en not_active Ceased
-
2009
- 2009-10-29 IL IL201842A patent/IL201842A0/en unknown
- 2009-11-09 NI NI200900205A patent/NI200900205A/es unknown
- 2009-11-09 ZA ZA2009/07858A patent/ZA200907858B/en unknown
- 2009-11-10 TN TNP2009000481A patent/TN2009000481A1/fr unknown
- 2009-11-30 CO CO09136461A patent/CO6241100A2/es not_active Application Discontinuation
- 2009-12-07 MA MA32411A patent/MA31497B1/fr unknown
- 2009-12-10 EC EC2009009792A patent/ECSP099792A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AP2009005057A0 (en) | 2009-12-31 |
| AU2008251425A1 (en) | 2008-11-20 |
| WO2008141227A1 (en) | 2008-11-20 |
| KR20100027134A (ko) | 2010-03-10 |
| MA31497B1 (fr) | 2010-07-01 |
| US7932277B2 (en) | 2011-04-26 |
| TN2009000481A1 (en) | 2011-03-31 |
| EP2185524A1 (en) | 2010-05-19 |
| EA200971041A1 (ru) | 2010-08-30 |
| CL2008001381A1 (es) | 2008-11-03 |
| BRPI0811447A2 (pt) | 2014-10-29 |
| CO6241100A2 (es) | 2011-01-20 |
| US20090297476A1 (en) | 2009-12-03 |
| IL201842A0 (en) | 2010-06-16 |
| AR066528A1 (es) | 2009-08-26 |
| CN101679277A (zh) | 2010-03-24 |
| CA2686546A1 (en) | 2008-11-20 |
| JP2010526834A (ja) | 2010-08-05 |
| ECSP099792A (es) | 2010-01-29 |
| ZA200907858B (en) | 2012-04-25 |
| MX2009012093A (es) | 2010-01-25 |
| NI200900205A (es) | 2010-10-11 |
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