SV2008002963A - Triazolopiridazinas como moduladores de tirosina cinasa referencia cruzada con solicitudes relacionadas ref. prd2584sv - Google Patents
Triazolopiridazinas como moduladores de tirosina cinasa referencia cruzada con solicitudes relacionadas ref. prd2584svInfo
- Publication number
- SV2008002963A SV2008002963A SV2008002963A SV2008002963A SV2008002963A SV 2008002963 A SV2008002963 A SV 2008002963A SV 2008002963 A SV2008002963 A SV 2008002963A SV 2008002963 A SV2008002963 A SV 2008002963A SV 2008002963 A SV2008002963 A SV 2008002963A
- Authority
- SV
- El Salvador
- Prior art keywords
- compounds
- modulators
- met
- triazolopiridazinas
- prd2584sv
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/5025—Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Psychiatry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Cosmetics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Materials For Medical Uses (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
LA INVENCIÓN ESTÁ DIRIGIDA A COMPUESTOS DE TRIAZOLOPIRIDAZINA DE LA FÓRMULA (I): (VER FORMULA); EN DONDE R1, R5, R6, R7, R8, Y A SON COMO SE DEFINE AQUÍ, EL USO DE DICHOS COMPUESTOS COMO MODULADORES DE PROTEÍNA TIROSINA CINASA, PARTICULARMENTE INHIBIDORES DE C-MET, Y EL USO DE DICHOS COMPUESTOS PARA REDUCIR O INHIBIR LA ACTIVIDAD DE CINASA DE C-MET EN UNA CÉLULA O UN SUJETO, Y MODULAR LA EXPRESIÓN DE C-MET EN UNA CÉLULA O UN SUJETO, Y EL USO DE DICHOS COMPUESTOS PARA PREVENIR O TRATAR EN UN SUJETO UN TRASTORNO PROLIFERATIVO DE CÉLULAS Y/O TRASTORNOS RELACIONADOS CON C-MET; LA PRESENTE INVENCIÓN ESTÁ DIRIGIDA ADEMÁS A 25 COMPOSICIONES FARMACÉUTICAS QUE COMPRENDEN LOS COMPUESTOS DE LA PRESENTE INVENCIÓN Y A MÉTODOS PARA TRATAR CONDICIONES TALES COMO CÁNCERES Y OTROS TRASTORNOS PROLIFERATIVOS DE CÉLULAS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75263405P | 2005-12-21 | 2005-12-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
SV2008002963A true SV2008002963A (es) | 2010-01-18 |
Family
ID=37964498
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SV2008002963A SV2008002963A (es) | 2005-12-21 | 2008-06-20 | Triazolopiridazinas como moduladores de tirosina cinasa referencia cruzada con solicitudes relacionadas ref. prd2584sv |
Country Status (40)
Country | Link |
---|---|
US (2) | US8030305B2 (es) |
EP (1) | EP1966214B9 (es) |
JP (1) | JP5292102B2 (es) |
KR (1) | KR101412675B1 (es) |
CN (1) | CN101374843B (es) |
AP (1) | AP3433A (es) |
AR (1) | AR058703A1 (es) |
AU (1) | AU2006331912B2 (es) |
BR (1) | BRPI0620292B1 (es) |
CA (1) | CA2634721C (es) |
CR (1) | CR10170A (es) |
CY (1) | CY1118846T1 (es) |
DK (1) | DK1966214T3 (es) |
EA (1) | EA015754B1 (es) |
EC (1) | ECSP088573A (es) |
ES (1) | ES2612377T3 (es) |
GT (1) | GT200800105A (es) |
HN (1) | HN2008000931A (es) |
HR (1) | HRP20170103T1 (es) |
HU (1) | HUE030390T2 (es) |
IL (1) | IL192108A (es) |
LT (1) | LT1966214T (es) |
MA (1) | MA30084B1 (es) |
ME (1) | ME02736B (es) |
MX (1) | MX2008008277A (es) |
MY (1) | MY159523A (es) |
NI (1) | NI200800179A (es) |
NO (1) | NO340958B1 (es) |
NZ (1) | NZ568807A (es) |
PE (2) | PE20070752A1 (es) |
PL (1) | PL1966214T3 (es) |
PT (1) | PT1966214T (es) |
RS (1) | RS55630B1 (es) |
SV (1) | SV2008002963A (es) |
TN (1) | TNSN08278A1 (es) |
TW (1) | TWI399378B (es) |
UA (1) | UA98297C2 (es) |
UY (1) | UY30041A1 (es) |
WO (1) | WO2007075567A1 (es) |
ZA (1) | ZA200806277B (es) |
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US10022352B2 (en) | 2006-04-07 | 2018-07-17 | Vertex Pharmaceuticals Incorporated | Modulators of ATP-binding cassette transporters |
PL3327016T3 (pl) | 2006-04-07 | 2021-10-04 | Vertex Pharmaceuticals Incorporated | Wytwarzanie modulatorów transporterów posiadających kasetę wiążącą ATP |
CA2651979A1 (en) * | 2006-05-30 | 2007-12-06 | Pfizer Products Inc. | Triazolopyridazine derivatives |
US8217177B2 (en) | 2006-07-14 | 2012-07-10 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
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US8198448B2 (en) | 2006-07-14 | 2012-06-12 | Amgen Inc. | Fused heterocyclic derivatives and methods of use |
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KR101083177B1 (ko) * | 2006-10-23 | 2011-11-11 | 에스지엑스 파마슈티컬스, 인코포레이티드 | 트리아졸로-피리다진 단백질 키나제 조정제 |
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US8563573B2 (en) | 2007-11-02 | 2013-10-22 | Vertex Pharmaceuticals Incorporated | Azaindole derivatives as CFTR modulators |
ME02372B (me) | 2006-11-22 | 2016-06-20 | Incyte Holdings Corp | Imidazotriazini i imidazopiramidini kao inhibitori kinaze |
DE102007026341A1 (de) | 2007-06-06 | 2008-12-11 | Merck Patent Gmbh | Benzoxazolonderivate |
WO2008155378A1 (en) * | 2007-06-21 | 2008-12-24 | Janssen Pharmaceutica Nv | Polymorphic and hydrate forms, salts and process for preparing 6-{difluoro[6-(1-methyl-1h-pyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazin-3-yl]methyl}quinoline |
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- 2008-06-20 TN TNP2008000278A patent/TNSN08278A1/en unknown
- 2008-07-03 NO NO20083013A patent/NO340958B1/no unknown
- 2008-07-18 ZA ZA200806277A patent/ZA200806277B/xx unknown
- 2008-07-21 CR CR10170A patent/CR10170A/es not_active Application Discontinuation
- 2008-08-07 US US12/187,524 patent/US8173654B2/en active Active
-
2017
- 2017-01-23 HR HRP20170103TT patent/HRP20170103T1/hr unknown
- 2017-02-01 CY CY20171100145T patent/CY1118846T1/el unknown
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