SU1436875A3 - Способ получени производных силибинина - Google Patents

Способ получени производных силибинина Download PDF

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Publication number
SU1436875A3
SU1436875A3 SU853985401A SU3985401A SU1436875A3 SU 1436875 A3 SU1436875 A3 SU 1436875A3 SU 853985401 A SU853985401 A SU 853985401A SU 3985401 A SU3985401 A SU 3985401A SU 1436875 A3 SU1436875 A3 SU 1436875A3
Authority
SU
USSR - Soviet Union
Prior art keywords
silibinin
animals
ethyl acetate
burns
ethanol
Prior art date
Application number
SU853985401A
Other languages
English (en)
Russian (ru)
Inventor
Браатц Райнхард
Герлер Клаус
Хальбах Гюнтер
Зойке Хартвиг
Шмидт Карлхайнц
Original Assignee
Др.Мадаус Унд Ко (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Др.Мадаус Унд Ко (Фирма) filed Critical Др.Мадаус Унд Ко (Фирма)
Application granted granted Critical
Publication of SU1436875A3 publication Critical patent/SU1436875A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Silicon Compounds (AREA)
SU853985401A 1984-11-22 1985-11-21 Способ получени производных силибинина SU1436875A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843442639 DE3442639A1 (de) 1984-11-22 1984-11-22 Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten

Publications (1)

Publication Number Publication Date
SU1436875A3 true SU1436875A3 (ru) 1988-11-07

Family

ID=6250903

Family Applications (1)

Application Number Title Priority Date Filing Date
SU853985401A SU1436875A3 (ru) 1984-11-22 1985-11-21 Способ получени производных силибинина

Country Status (29)

Country Link
JP (1) JPS61143377A (hu)
KR (1) KR870001020B1 (hu)
AR (1) AR240931A1 (hu)
AT (1) AT393268B (hu)
BE (1) BE903693A (hu)
CA (1) CA1337124C (hu)
CH (1) CH659473A5 (hu)
CS (1) CS273610B2 (hu)
DD (1) DD259191A1 (hu)
DE (1) DE3442639A1 (hu)
DK (1) DK164865C (hu)
EG (1) EG19424A (hu)
ES (1) ES8609311A1 (hu)
FI (1) FI84064C (hu)
FR (1) FR2573427B1 (hu)
GB (1) GB2167414B (hu)
HU (1) HU195503B (hu)
IE (1) IE58791B1 (hu)
IT (1) IT1190426B (hu)
LU (1) LU86163A1 (hu)
MX (1) MX168415B (hu)
NL (1) NL192387C (hu)
NO (1) NO160205C (hu)
PL (1) PL146890B1 (hu)
PT (1) PT81532B (hu)
SE (1) SE465676B (hu)
SU (1) SU1436875A3 (hu)
YU (1) YU43689B (hu)
ZA (1) ZA858951B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716918D0 (en) * 1987-07-17 1987-08-26 Inverni Della Beffa Spa Soluble derivatives of silybin
US5262439A (en) * 1992-04-30 1993-11-16 The Regents Of The University Of California Soluble analogs of probucol
BRPI0608402B8 (pt) * 2005-03-11 2021-05-25 Armaron Bio Pty Ltd compostos de flavonóide e composições compreendendo os mesmos
CN102300570B (zh) * 2007-11-15 2015-01-14 马道斯有限责任公司 用于治疗肝炎的水飞蓟宾组分
RU2482844C2 (ru) * 2007-11-15 2013-05-27 Мадаус Гмбх Силибининовый компонент для лечения гепатита
CA2761656C (en) * 2009-05-14 2017-02-07 Lucio Claudio Rovati Amorphous silibinin for the treatment of viral hepatitis
AU2013286721B2 (en) 2012-07-05 2018-04-26 Nutramax Laboratories, Inc. Compositions comprising a sulforaphane or a sulforaphane precursor and milk thistle extract or powder
CN103113359B (zh) * 2013-02-22 2016-01-06 西安安健药业有限公司 水飞蓟宾二偏琥珀酸酯及其药用盐
CN103193768B (zh) * 2013-02-22 2016-03-30 西安安健药业有限公司 治疗肝病的水飞蓟宾二偏琥珀酸酯异构体
CN103172622B (zh) * 2013-02-22 2015-11-04 西安安健药业有限公司 水飞蓟宾二偏琥珀酸酯的活性异构体

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963318A1 (de) * 1969-12-17 1971-06-24 Schwabe Willmar Gmbh & Co Silybinhalbester der Bernsteinsaeure und der Phthalsaeure,ihre Salze mit pharmakologisch vertraglichen Basen,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Патент DE № 1923082, кл.12 q 24, опублик. 1974. Вьшоженна за вка DE № 3225688, кл. С 07 D 407/02, опублик,02.02.84. Вейганд-Хильгентаг, Методы экспе ;-: римента в органической химии Хими . . *

Also Published As

Publication number Publication date
FI854535A (fi) 1986-05-23
PT81532A (de) 1985-12-01
CS273610B2 (en) 1991-03-12
IE58791B1 (en) 1993-11-17
LU86163A1 (de) 1986-03-24
GB2167414B (en) 1989-01-11
GB2167414A (en) 1986-05-29
PL256374A1 (en) 1986-12-02
BE903693A (fr) 1986-05-22
FR2573427A1 (fr) 1986-05-23
AR240931A1 (es) 1991-03-27
DK164865C (da) 1993-01-18
CS837885A2 (en) 1990-08-14
DD259191A1 (de) 1988-08-17
NO160205B (no) 1988-12-12
FI854535A0 (fi) 1985-11-18
NL192387B (nl) 1997-03-03
DK537785A (da) 1986-05-23
FI84064B (fi) 1991-06-28
IE852808L (en) 1986-05-22
HUT40114A (en) 1986-11-28
ES549116A0 (es) 1986-09-01
YU178685A (en) 1988-02-29
IT8522932A0 (it) 1985-11-21
CH659473A5 (de) 1987-01-30
IT1190426B (it) 1988-02-16
DE3442639C2 (hu) 1989-08-10
FI84064C (fi) 1991-10-10
FR2573427B1 (fr) 1989-03-10
ZA858951B (en) 1986-08-27
PL146890B1 (en) 1989-03-31
SE465676B (sv) 1991-10-14
DK164865B (da) 1992-08-31
DE3442639A1 (de) 1986-05-22
GB8528226D0 (en) 1985-12-18
ATA337185A (de) 1991-02-15
EG19424A (en) 1995-02-28
NL192387C (nl) 1997-07-04
SE8505487L (sv) 1986-05-23
YU43689B (en) 1989-10-31
AT393268B (de) 1991-09-25
PT81532B (pt) 1987-11-11
ES8609311A1 (es) 1986-09-01
DK537785D0 (da) 1985-11-21
SE8505487D0 (sv) 1985-11-20
HU195503B (en) 1988-05-30
NO854655L (no) 1986-05-23
MX168415B (es) 1993-05-24
NL8503171A (nl) 1986-06-16
JPS61143377A (ja) 1986-07-01
NO160205C (no) 1989-03-22
AR240931A2 (es) 1991-03-27
KR870001020B1 (ko) 1987-05-23
JPH0432073B2 (hu) 1992-05-28
KR860004056A (ko) 1986-06-16
CA1337124C (en) 1995-09-26

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