YU178685A - Process for preparing derivatives of silibinine - Google Patents

Process for preparing derivatives of silibinine

Info

Publication number
YU178685A
YU178685A YU01786/85A YU178685A YU178685A YU 178685 A YU178685 A YU 178685A YU 01786/85 A YU01786/85 A YU 01786/85A YU 178685 A YU178685 A YU 178685A YU 178685 A YU178685 A YU 178685A
Authority
YU
Yugoslavia
Prior art keywords
silibinine
preparing derivatives
derivatives
preparing
Prior art date
Application number
YU01786/85A
Other versions
YU43689B (en
Inventor
R Braatz
K Goerler
G Halbach
H Soicke
K Schmidt
Original Assignee
Madaus & Co Dr
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Madaus & Co Dr filed Critical Madaus & Co Dr
Priority to SI8511786A priority Critical patent/SI8511786A8/en
Publication of YU178685A publication Critical patent/YU178685A/en
Publication of YU43689B publication Critical patent/YU43689B/en
Priority to HRP-1786/85A priority patent/HRP950126B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Silicon Compounds (AREA)
YU1786/85A 1984-11-22 1985-11-14 Process for preparing derivatives of silibinine YU43689B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
SI8511786A SI8511786A8 (en) 1984-11-22 1985-11-14 Process for preparation of derivatives of sylibinine
HRP-1786/85A HRP950126B1 (en) 1984-11-22 1995-03-16 Process for the preparation of silibinine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843442639 DE3442639A1 (en) 1984-11-22 1984-11-22 FLAVOLIGNANE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number Publication Date
YU178685A true YU178685A (en) 1988-02-29
YU43689B YU43689B (en) 1989-10-31

Family

ID=6250903

Family Applications (1)

Application Number Title Priority Date Filing Date
YU1786/85A YU43689B (en) 1984-11-22 1985-11-14 Process for preparing derivatives of silibinine

Country Status (29)

Country Link
JP (1) JPS61143377A (en)
KR (1) KR870001020B1 (en)
AR (1) AR240931A1 (en)
AT (1) AT393268B (en)
BE (1) BE903693A (en)
CA (1) CA1337124C (en)
CH (1) CH659473A5 (en)
CS (1) CS273610B2 (en)
DD (1) DD259191A1 (en)
DE (1) DE3442639A1 (en)
DK (1) DK164865C (en)
EG (1) EG19424A (en)
ES (1) ES8609311A1 (en)
FI (1) FI84064C (en)
FR (1) FR2573427B1 (en)
GB (1) GB2167414B (en)
HU (1) HU195503B (en)
IE (1) IE58791B1 (en)
IT (1) IT1190426B (en)
LU (1) LU86163A1 (en)
MX (1) MX168415B (en)
NL (1) NL192387C (en)
NO (1) NO160205C (en)
PL (1) PL146890B1 (en)
PT (1) PT81532B (en)
SE (1) SE465676B (en)
SU (1) SU1436875A3 (en)
YU (1) YU43689B (en)
ZA (1) ZA858951B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716918D0 (en) * 1987-07-17 1987-08-26 Inverni Della Beffa Spa Soluble derivatives of silybin
US5262439A (en) * 1992-04-30 1993-11-16 The Regents Of The University Of California Soluble analogs of probucol
DK1856085T3 (en) * 2005-03-11 2015-10-05 Howard Florey Inst Pty Ltd FLAVONOID COMPOUNDS AND APPLICATIONS THEREOF
CN102300570B (en) * 2007-11-15 2015-01-14 马道斯有限责任公司 Silibinin Component For Treatment Of Hepatitis
RU2482844C2 (en) * 2007-11-15 2013-05-27 Мадаус Гмбх Silibilin component for treating hepatitis
EP2430017B1 (en) * 2009-05-14 2016-06-29 Madaus GmbH A method for preparing AMORPHOUS SILIBININ
PL3409280T3 (en) 2012-07-05 2021-10-18 Nutramax Laboratories, Inc. Compositions comprising a sulforaphane and milk thistle extract or powder
CN103193768B (en) * 2013-02-22 2016-03-30 西安安健药业有限公司 The silybin bis-bias succinate isomer for the treatment of hepatopathy
CN103172622B (en) * 2013-02-22 2015-11-04 西安安健药业有限公司 The active isomer of silybin bis-bias succinate
CN103113359B (en) * 2013-02-22 2016-01-06 西安安健药业有限公司 Silybin bis-bias succinate and pharmaceutical salts thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963318A1 (en) * 1969-12-17 1971-06-24 Schwabe Willmar Gmbh & Co Silybin esters with hepotoprotactant acti- - vity

Also Published As

Publication number Publication date
FI84064C (en) 1991-10-10
DK164865C (en) 1993-01-18
IT8522932A0 (en) 1985-11-21
NL8503171A (en) 1986-06-16
IE58791B1 (en) 1993-11-17
AR240931A2 (en) 1991-03-27
IE852808L (en) 1986-05-22
PT81532A (en) 1985-12-01
ZA858951B (en) 1986-08-27
CS837885A2 (en) 1990-08-14
FI854535A (en) 1986-05-23
DE3442639C2 (en) 1989-08-10
PL256374A1 (en) 1986-12-02
KR860004056A (en) 1986-06-16
ES8609311A1 (en) 1986-09-01
NL192387B (en) 1997-03-03
YU43689B (en) 1989-10-31
FI84064B (en) 1991-06-28
CA1337124C (en) 1995-09-26
MX168415B (en) 1993-05-24
NL192387C (en) 1997-07-04
JPS61143377A (en) 1986-07-01
DE3442639A1 (en) 1986-05-22
NO854655L (en) 1986-05-23
HU195503B (en) 1988-05-30
KR870001020B1 (en) 1987-05-23
DK537785A (en) 1986-05-23
AT393268B (en) 1991-09-25
LU86163A1 (en) 1986-03-24
NO160205B (en) 1988-12-12
GB2167414A (en) 1986-05-29
AR240931A1 (en) 1991-03-27
PT81532B (en) 1987-11-11
EG19424A (en) 1995-02-28
PL146890B1 (en) 1989-03-31
SE465676B (en) 1991-10-14
HUT40114A (en) 1986-11-28
CS273610B2 (en) 1991-03-12
FI854535A0 (en) 1985-11-18
DK537785D0 (en) 1985-11-21
ES549116A0 (en) 1986-09-01
SU1436875A3 (en) 1988-11-07
GB2167414B (en) 1989-01-11
CH659473A5 (en) 1987-01-30
FR2573427B1 (en) 1989-03-10
BE903693A (en) 1986-05-22
GB8528226D0 (en) 1985-12-18
ATA337185A (en) 1991-02-15
DD259191A1 (en) 1988-08-17
SE8505487L (en) 1986-05-23
SE8505487D0 (en) 1985-11-20
FR2573427A1 (en) 1986-05-23
IT1190426B (en) 1988-02-16
DK164865B (en) 1992-08-31
NO160205C (en) 1989-03-22
JPH0432073B2 (en) 1992-05-28

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