GB2167414B - Flavolignan derivatives and pharmaceutical compositions containing them - Google Patents

Flavolignan derivatives and pharmaceutical compositions containing them

Info

Publication number
GB2167414B
GB2167414B GB08528226A GB8528226A GB2167414B GB 2167414 B GB2167414 B GB 2167414B GB 08528226 A GB08528226 A GB 08528226A GB 8528226 A GB8528226 A GB 8528226A GB 2167414 B GB2167414 B GB 2167414B
Authority
GB
United Kingdom
Prior art keywords
flavolignan
derivatives
pharmaceutical compositions
compositions containing
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08528226A
Other languages
English (en)
Other versions
GB2167414A (en
GB8528226D0 (en
Inventor
Reinhard Braatz
Klaus Gorler
Gunter Halbach
Hartwig Soicke
Karlheinz Schmidt
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Madaus Holding GmbH
Original Assignee
Dr Madaus GmbH and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Madaus GmbH and Co filed Critical Dr Madaus GmbH and Co
Publication of GB8528226D0 publication Critical patent/GB8528226D0/en
Publication of GB2167414A publication Critical patent/GB2167414A/en
Application granted granted Critical
Publication of GB2167414B publication Critical patent/GB2167414B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Silicon Compounds (AREA)
GB08528226A 1984-11-22 1985-11-15 Flavolignan derivatives and pharmaceutical compositions containing them Expired GB2167414B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19843442639 DE3442639A1 (de) 1984-11-22 1984-11-22 Flavolignanderivate, verfahren zu deren herstellung und arzneimittel, die diese verbindungen enthalten

Publications (3)

Publication Number Publication Date
GB8528226D0 GB8528226D0 (en) 1985-12-18
GB2167414A GB2167414A (en) 1986-05-29
GB2167414B true GB2167414B (en) 1989-01-11

Family

ID=6250903

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08528226A Expired GB2167414B (en) 1984-11-22 1985-11-15 Flavolignan derivatives and pharmaceutical compositions containing them

Country Status (29)

Country Link
JP (1) JPS61143377A (hu)
KR (1) KR870001020B1 (hu)
AR (1) AR240931A1 (hu)
AT (1) AT393268B (hu)
BE (1) BE903693A (hu)
CA (1) CA1337124C (hu)
CH (1) CH659473A5 (hu)
CS (1) CS273610B2 (hu)
DD (1) DD259191A1 (hu)
DE (1) DE3442639A1 (hu)
DK (1) DK164865C (hu)
EG (1) EG19424A (hu)
ES (1) ES8609311A1 (hu)
FI (1) FI84064C (hu)
FR (1) FR2573427B1 (hu)
GB (1) GB2167414B (hu)
HU (1) HU195503B (hu)
IE (1) IE58791B1 (hu)
IT (1) IT1190426B (hu)
LU (1) LU86163A1 (hu)
MX (1) MX168415B (hu)
NL (1) NL192387C (hu)
NO (1) NO160205C (hu)
PL (1) PL146890B1 (hu)
PT (1) PT81532B (hu)
SE (1) SE465676B (hu)
SU (1) SU1436875A3 (hu)
YU (1) YU43689B (hu)
ZA (1) ZA858951B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8716918D0 (en) * 1987-07-17 1987-08-26 Inverni Della Beffa Spa Soluble derivatives of silybin
US5262439A (en) * 1992-04-30 1993-11-16 The Regents Of The University Of California Soluble analogs of probucol
NZ560633A (en) * 2005-03-11 2011-08-26 Neuprotect Pty Ltd Flavonoid compounds and uses thereof
RU2482844C2 (ru) * 2007-11-15 2013-05-27 Мадаус Гмбх Силибининовый компонент для лечения гепатита
MX2010005107A (es) * 2007-11-15 2010-05-27 Madaus Gmbh Componente de silibinina para tratamiento contra hepatitis.
CA2761656C (en) 2009-05-14 2017-02-07 Lucio Claudio Rovati Amorphous silibinin for the treatment of viral hepatitis
CN108355136B (zh) 2012-07-05 2021-12-07 纽崔玛氏科技有限责任公司 包含莱菔硫烷或莱菔硫烷前体和蕈类提取物或粉末的组合物
CN103172622B (zh) * 2013-02-22 2015-11-04 西安安健药业有限公司 水飞蓟宾二偏琥珀酸酯的活性异构体
CN103193768B (zh) * 2013-02-22 2016-03-30 西安安健药业有限公司 治疗肝病的水飞蓟宾二偏琥珀酸酯异构体
CN103113359B (zh) * 2013-02-22 2016-01-06 西安安健药业有限公司 水飞蓟宾二偏琥珀酸酯及其药用盐

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1963318A1 (de) * 1969-12-17 1971-06-24 Schwabe Willmar Gmbh & Co Silybinhalbester der Bernsteinsaeure und der Phthalsaeure,ihre Salze mit pharmakologisch vertraglichen Basen,Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von Arzneipraeparaten

Also Published As

Publication number Publication date
ZA858951B (en) 1986-08-27
YU178685A (en) 1988-02-29
PT81532B (pt) 1987-11-11
FI854535A0 (fi) 1985-11-18
DK537785D0 (da) 1985-11-21
NL192387B (nl) 1997-03-03
DK164865C (da) 1993-01-18
SE8505487D0 (sv) 1985-11-20
LU86163A1 (de) 1986-03-24
CS273610B2 (en) 1991-03-12
EG19424A (en) 1995-02-28
FR2573427A1 (fr) 1986-05-23
IE58791B1 (en) 1993-11-17
CS837885A2 (en) 1990-08-14
PT81532A (de) 1985-12-01
BE903693A (fr) 1986-05-22
CH659473A5 (de) 1987-01-30
IE852808L (en) 1986-05-22
SE8505487L (sv) 1986-05-23
CA1337124C (en) 1995-09-26
NO160205C (no) 1989-03-22
AT393268B (de) 1991-09-25
FR2573427B1 (fr) 1989-03-10
KR860004056A (ko) 1986-06-16
NL192387C (nl) 1997-07-04
ATA337185A (de) 1991-02-15
GB2167414A (en) 1986-05-29
HU195503B (en) 1988-05-30
DK537785A (da) 1986-05-23
HUT40114A (en) 1986-11-28
IT1190426B (it) 1988-02-16
ES8609311A1 (es) 1986-09-01
GB8528226D0 (en) 1985-12-18
MX168415B (es) 1993-05-24
NO160205B (no) 1988-12-12
YU43689B (en) 1989-10-31
ES549116A0 (es) 1986-09-01
DD259191A1 (de) 1988-08-17
NO854655L (no) 1986-05-23
NL8503171A (nl) 1986-06-16
PL256374A1 (en) 1986-12-02
DE3442639A1 (de) 1986-05-22
PL146890B1 (en) 1989-03-31
SE465676B (sv) 1991-10-14
SU1436875A3 (ru) 1988-11-07
IT8522932A0 (it) 1985-11-21
JPS61143377A (ja) 1986-07-01
FI84064B (fi) 1991-06-28
KR870001020B1 (ko) 1987-05-23
AR240931A1 (es) 1991-03-27
FI854535A (fi) 1986-05-23
FI84064C (fi) 1991-10-10
AR240931A2 (es) 1991-03-27
DE3442639C2 (hu) 1989-08-10
JPH0432073B2 (hu) 1992-05-28
DK164865B (da) 1992-08-31

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Legal Events

Date Code Title Description
732 Registration of transactions, instruments or events in the register (sect. 32/1977)