SK288072B6 - Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use - Google Patents

Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use Download PDF

Info

Publication number
SK288072B6
SK288072B6 SK443-2002A SK4432002A SK288072B6 SK 288072 B6 SK288072 B6 SK 288072B6 SK 4432002 A SK4432002 A SK 4432002A SK 288072 B6 SK288072 B6 SK 288072B6
Authority
SK
Slovakia
Prior art keywords
carnitine
osmotic
solution according
agent
concentration
Prior art date
Application number
SK443-2002A
Other languages
English (en)
Slovak (sk)
Other versions
SK4432002A3 (en
Inventor
Arduino Arduini
Original Assignee
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.
Publication of SK4432002A3 publication Critical patent/SK4432002A3/sk
Publication of SK288072B6 publication Critical patent/SK288072B6/sk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SK443-2002A 1999-10-11 1999-10-11 Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use SK288072B6 (sk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT1999/000317 WO2001026649A1 (fr) 1999-10-11 1999-10-11 Utilisation de la l-carnitine et de ses derives alkanoyles comme agents osmotiques dans des solutions a usage medical

Publications (2)

Publication Number Publication Date
SK4432002A3 SK4432002A3 (en) 2002-08-06
SK288072B6 true SK288072B6 (sk) 2013-05-03

Family

ID=11333127

Family Applications (1)

Application Number Title Priority Date Filing Date
SK443-2002A SK288072B6 (sk) 1999-10-11 1999-10-11 Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use

Country Status (20)

Country Link
US (2) US6822002B1 (fr)
EP (1) EP1220670B1 (fr)
JP (1) JP4638106B2 (fr)
KR (1) KR100642731B1 (fr)
AT (1) ATE336243T1 (fr)
AU (1) AU1073400A (fr)
CA (1) CA2386826C (fr)
CY (1) CY1106203T1 (fr)
CZ (1) CZ303870B6 (fr)
DE (1) DE69932860T2 (fr)
DK (1) DK1220670T3 (fr)
ES (1) ES2270620T3 (fr)
HK (1) HK1046090B (fr)
HU (1) HUP0203441A3 (fr)
MX (1) MXPA02003635A (fr)
PL (1) PL213131B1 (fr)
PT (1) PT1220670E (fr)
SI (1) SI1220670T1 (fr)
SK (1) SK288072B6 (fr)
WO (1) WO2001026649A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770148B1 (en) 1998-12-04 2004-08-03 Baxter International Inc. Peritoneal dialysis solution containing modified icodextrins
ITRM20010337A1 (it) * 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
US7053059B2 (en) 2003-07-25 2006-05-30 Baxter International Inc. Dialysis solutions with reduced levels of glucose degradation products
ITRM20040346A1 (it) 2004-07-13 2004-10-13 Sigma Tau Ind Farmaceuti Uso della l-carnitina per il trattamento di patologie cardiovascolari.
JP2006075195A (ja) * 2004-09-07 2006-03-23 Jms Co Ltd Ｌカルニチン含有腹膜透析液
TWI388318B (zh) * 2005-03-10 2013-03-11 Sigma Tau Ind Farmaceuti 具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液
US20070087975A1 (en) * 2005-10-17 2007-04-19 Sigma-Tau Industrie Farmaceutiche Riunite Spa Compound useful for the prevention and treatment of left ventricular hypertrophy in dialysed patients
RU2426561C2 (ru) * 2006-01-30 2011-08-20 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Способы и устройство для перитонеального диализа
US8876753B2 (en) 2006-01-30 2014-11-04 The Regents Of The University Of California Peritoneal dialysis methods and apparatus
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
ES2396650B2 (es) * 2011-07-21 2013-07-16 Universidad Complutense De Madrid Uso de una composición en la elaboración de una solución de diálisis para el tratamiento de las enfermedades cerebrovasculares mediante diálisis peritoneal.
TWI454287B (zh) * 2012-11-21 2014-10-01 Taipei Veteran General Hospital 治療纖維化之透析液
US9539411B2 (en) 2013-03-13 2017-01-10 W. L. Gore & Associates, Inc. Deconstructable endoluminal devices and related systems and methods
CN103330715B (zh) * 2013-07-01 2015-09-02 华仁药业股份有限公司 一种抗腹膜纤维化的腹膜透析液
CN103463081B (zh) * 2013-09-27 2015-10-21 华仁药业股份有限公司 腹膜透析液
DE102015014699A1 (de) * 2015-11-13 2017-05-18 Fresenius Medical Care Deutschland Gmbh Dialyselösung mit wenigstens einem Osmotikum
EP3912656A1 (fr) 2020-05-19 2021-11-24 CoreQuest Sagl Solution de dialyse péritonéale
EP4029507A1 (fr) 2021-01-19 2022-07-20 Iperboreal Pharma Srl Solution de dialyse péritonéale pour sujets hypertensifs

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1156741B (it) 1978-05-15 1987-02-04 Sigma Tau Ind Farmaceuti Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi
IT1120033B (it) * 1979-10-05 1986-03-19 Sigma Tau Ind Farmaceuti Composizione farmaceutica comprendente-carnitina adatta per l'alimentazione parenterale
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
JPH04320145A (ja) * 1991-04-19 1992-11-10 Ricoh Co Ltd ファクシミリ装置
IT1261695B (it) 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
IT1283137B1 (it) 1996-07-09 1998-04-07 Bieffe Medital Spa Agenti osmotici alternativi e relative soluzioni per dialisi peritoneale
JPH1094598A (ja) 1996-07-31 1998-04-14 Baxter Internatl Inc 腹膜透析液
US5973004A (en) * 1997-04-04 1999-10-26 Howard; James R. L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism
US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
GB9714218D0 (en) 1997-07-04 1997-09-10 Allied Therapeutics Ltd Peritoneal dialysis fluid
JPH1149671A (ja) 1997-08-06 1999-02-23 Baxter Internatl Inc 腹膜透析液
US6537976B1 (en) * 1997-08-07 2003-03-25 Ajay Gupta Dialysis solutions containing water soluble vitamins and nutrients
JPH1171286A (ja) 1997-08-29 1999-03-16 Terumo Corp 腹膜透析液
JPH1171273A (ja) 1997-08-29 1999-03-16 Terumo Corp 腹膜透析液
WO1999035917A1 (fr) * 1998-01-15 1999-07-22 Edward Hirschberg Procedes d'infusion de substances phytochimiques, d'aliments fonctionnels et d'autres compositions dans des produits alimentaires

Also Published As

Publication number Publication date
US7932291B2 (en) 2011-04-26
CZ303870B6 (cs) 2013-06-05
SI1220670T1 (sl) 2006-12-31
KR100642731B1 (ko) 2006-11-03
MXPA02003635A (es) 2002-10-23
JP2003511413A (ja) 2003-03-25
CA2386826A1 (fr) 2001-04-19
CZ20021063A3 (cs) 2002-08-14
DK1220670T3 (da) 2006-12-18
EP1220670A1 (fr) 2002-07-10
SK4432002A3 (en) 2002-08-06
HK1046090A1 (en) 2002-12-27
DE69932860D1 (de) 2006-09-28
WO2001026649A1 (fr) 2001-04-19
AU1073400A (en) 2001-04-23
HUP0203441A3 (en) 2004-01-28
EP1220670B1 (fr) 2006-08-16
US20050085542A1 (en) 2005-04-21
JP4638106B2 (ja) 2011-02-23
KR20020038809A (ko) 2002-05-23
PL213131B1 (pl) 2013-01-31
CA2386826C (fr) 2010-04-20
DE69932860T2 (de) 2007-08-30
PL354414A1 (en) 2004-01-12
US6822002B1 (en) 2004-11-23
HUP0203441A2 (hu) 2003-03-28
HK1046090B (zh) 2007-06-29
CY1106203T1 (el) 2011-06-08
PT1220670E (pt) 2006-10-31
ATE336243T1 (de) 2006-09-15
ES2270620T3 (es) 2007-04-01

Similar Documents

Publication Publication Date Title
SK288072B6 (sk) Use of L-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use
EP0456806B1 (fr) Solution de dialyse peritoneale tamponnee a l'histidine
CA2129998C (fr) Solutions ameliorees d'acides amines pour le traitement des patients sous dialyse peritoneale
EP3219315B1 (fr) Mélange d'acides carboxyliques pour traiter des patients avec une insuffisance rénale
KR20050089833A (ko) 이코덱스트린을 함유하는 생체친화성 투석액
EA010948B1 (ru) Фармацевтическая композиция, содержащая лактат, и ее применение
US20090232908A1 (en) Stable aqueous solution containing sodium pyruvate, and the preparation and use thereof
KR101434329B1 (ko) 체온 저하 억제제
EP0355453A2 (fr) Utilisation de l'acide 3-hydroxy-butyrique comme source d'énergie
Lameire et al. Peritoneal dialysis solutions containing glycerol and amino acids
JPH06509362A (ja) アルファ−ケトルグルタル酸塩の用法
MXPA02000912A (es) Uso de l-carnitina y sus derivados alcanoilo para la preparacion de un medicamento util para el tratamiento de pacientes que sufren nefropatias diabeticas o por insuficiencia metabolica.
JPH1171273A (ja) 腹膜透析液
KR20050044594A (ko) 발기 기능장애의 치료를 위한 알카노일 ｌ-카르니틴의 용도
TWI227672B (en) Solutions for medical use containing L-carnitine and its alkanoyl derivatives as osmotic agents
EP1937245A1 (fr) Compose utile pour la prevention et le traitement de l'hypertrophie ventriculaire gauche chez des patients dialyses
Misra et al. Peritoneal Dialysis in Diabetic End-Stage Kidney Disease
JP2003095937A (ja) 末梢静脈用輸液
William et al. New perspectives in peritoneal dialysis fluids
Hecking et al. Supplementation with essential amino acids or α-keto analogues in patients on long-term hemodialysis
Cancarini Strategy for preventing peritoneal dialysis failure
KR20070039541A (ko) 심혈관 질환 치료를 위한 ｌ-카르니틴 및 글루코오스의용도

Legal Events

Date Code Title Description
MM4A Patent lapsed due to non-payment of maintenance fees

Effective date: 20171011