CY1106203T1 - Η χρηση της l-καρνιτινης και των αλκανοϋλο παραγωγων αυτης σαν ωσμωτικων παραγοντων σε διαλυματα για ιατρικη χρηση - Google Patents
Η χρηση της l-καρνιτινης και των αλκανοϋλο παραγωγων αυτης σαν ωσμωτικων παραγοντων σε διαλυματα για ιατρικη χρησηInfo
- Publication number
- CY1106203T1 CY1106203T1 CY20061101485T CY061101485T CY1106203T1 CY 1106203 T1 CY1106203 T1 CY 1106203T1 CY 20061101485 T CY20061101485 T CY 20061101485T CY 061101485 T CY061101485 T CY 061101485T CY 1106203 T1 CY1106203 T1 CY 1106203T1
- Authority
- CY
- Cyprus
- Prior art keywords
- carnitine
- solutions
- osmotic agents
- alkanoyl derivatives
- medical use
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 2
- 239000002357 osmotic agent Substances 0.000 title abstract 2
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- External Artificial Organs (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Περιγράφεται η χρήση της L-καρνιτίνης και των αλκανοϋλο παραγώγων αυτής, προαιρετικά στη μορφή ενός φαρμακευτικά αποδεκτού άλατος, σαν ωσμωτικών παραγόντων στην παρασκευή διαλυμάτων για ιατρική χρήση, ειδικότερα για περιτοναϊκή κάθαρση.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IT1999/000317 WO2001026649A1 (en) | 1999-10-11 | 1999-10-11 | Use of l-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1106203T1 true CY1106203T1 (el) | 2011-06-08 |
Family
ID=11333127
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20061101485T CY1106203T1 (el) | 1999-10-11 | 2006-10-16 | Η χρηση της l-καρνιτινης και των αλκανοϋλο παραγωγων αυτης σαν ωσμωτικων παραγοντων σε διαλυματα για ιατρικη χρηση |
Country Status (20)
Country | Link |
---|---|
US (2) | US6822002B1 (el) |
EP (1) | EP1220670B1 (el) |
JP (1) | JP4638106B2 (el) |
KR (1) | KR100642731B1 (el) |
AT (1) | ATE336243T1 (el) |
AU (1) | AU1073400A (el) |
CA (1) | CA2386826C (el) |
CY (1) | CY1106203T1 (el) |
CZ (1) | CZ303870B6 (el) |
DE (1) | DE69932860T2 (el) |
DK (1) | DK1220670T3 (el) |
ES (1) | ES2270620T3 (el) |
HK (1) | HK1046090B (el) |
HU (1) | HUP0203441A3 (el) |
MX (1) | MXPA02003635A (el) |
PL (1) | PL213131B1 (el) |
PT (1) | PT1220670E (el) |
SI (1) | SI1220670T1 (el) |
SK (1) | SK288072B6 (el) |
WO (1) | WO2001026649A1 (el) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6770148B1 (en) | 1998-12-04 | 2004-08-03 | Baxter International Inc. | Peritoneal dialysis solution containing modified icodextrins |
ITRM20010337A1 (it) * | 2001-06-14 | 2002-12-16 | Sigma Tau Ind Farmaceuti | Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati. |
US8173618B2 (en) * | 2003-07-25 | 2012-05-08 | University Of Massachusetts | Formulations for reducing neuronal degeneration |
US7053059B2 (en) | 2003-07-25 | 2006-05-30 | Baxter International Inc. | Dialysis solutions with reduced levels of glucose degradation products |
ITRM20040346A1 (it) | 2004-07-13 | 2004-10-13 | Sigma Tau Ind Farmaceuti | Uso della l-carnitina per il trattamento di patologie cardiovascolari. |
JP2006075195A (ja) * | 2004-09-07 | 2006-03-23 | Jms Co Ltd | Lカルニチン含有腹膜透析液 |
TWI388318B (zh) * | 2005-03-10 | 2013-03-11 | Sigma Tau Ind Farmaceuti | 具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液 |
US20070087975A1 (en) * | 2005-10-17 | 2007-04-19 | Sigma-Tau Industrie Farmaceutiche Riunite Spa | Compound useful for the prevention and treatment of left ventricular hypertrophy in dialysed patients |
US8876753B2 (en) | 2006-01-30 | 2014-11-04 | The Regents Of The University Of California | Peritoneal dialysis methods and apparatus |
EP1979020A4 (en) * | 2006-01-30 | 2011-03-30 | Univ California | PERITONEAL DIALYSIS METHODS AND APPARATUS |
US8597640B2 (en) * | 2007-10-31 | 2013-12-03 | University Of Massachusetts Lowell | Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging |
ES2396650B2 (es) * | 2011-07-21 | 2013-07-16 | Universidad Complutense De Madrid | Uso de una composición en la elaboración de una solución de diálisis para el tratamiento de las enfermedades cerebrovasculares mediante diálisis peritoneal. |
TWI454287B (zh) * | 2012-11-21 | 2014-10-01 | Taipei Veteran General Hospital | 治療纖維化之透析液 |
US9539411B2 (en) | 2013-03-13 | 2017-01-10 | W. L. Gore & Associates, Inc. | Deconstructable endoluminal devices and related systems and methods |
CN103330715B (zh) * | 2013-07-01 | 2015-09-02 | 华仁药业股份有限公司 | 一种抗腹膜纤维化的腹膜透析液 |
CN103463081B (zh) * | 2013-09-27 | 2015-10-21 | 华仁药业股份有限公司 | 腹膜透析液 |
DE102015014699A1 (de) * | 2015-11-13 | 2017-05-18 | Fresenius Medical Care Deutschland Gmbh | Dialyselösung mit wenigstens einem Osmotikum |
EP3912656A1 (en) * | 2020-05-19 | 2021-11-24 | CoreQuest Sagl | Peritoneal dialysis solution |
EP4029507A1 (en) | 2021-01-19 | 2022-07-20 | Iperboreal Pharma Srl | Peritoneal dialysis solution for hypertensive subjects |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1156741B (it) | 1978-05-15 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi |
IT1120033B (it) | 1979-10-05 | 1986-03-19 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica comprendente-carnitina adatta per l'alimentazione parenterale |
CH664374A5 (de) * | 1985-02-27 | 1988-02-29 | Lonza Ag | Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg. |
JPH04320145A (ja) * | 1991-04-19 | 1992-11-10 | Ricoh Co Ltd | ファクシミリ装置 |
IT1261695B (it) * | 1993-06-02 | 1996-05-29 | Sigma Tau Ind Farmaceuti | Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. |
IT1283137B1 (it) | 1996-07-09 | 1998-04-07 | Bieffe Medital Spa | Agenti osmotici alternativi e relative soluzioni per dialisi peritoneale |
JPH1094598A (ja) | 1996-07-31 | 1998-04-14 | Baxter Internatl Inc | 腹膜透析液 |
US5973004A (en) * | 1997-04-04 | 1999-10-26 | Howard; James R. | L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism |
US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
GB9714218D0 (en) | 1997-07-04 | 1997-09-10 | Allied Therapeutics Ltd | Peritoneal dialysis fluid |
JPH1149671A (ja) | 1997-08-06 | 1999-02-23 | Baxter Internatl Inc | 腹膜透析液 |
US6537976B1 (en) * | 1997-08-07 | 2003-03-25 | Ajay Gupta | Dialysis solutions containing water soluble vitamins and nutrients |
JPH1171273A (ja) | 1997-08-29 | 1999-03-16 | Terumo Corp | 腹膜透析液 |
JPH1171286A (ja) | 1997-08-29 | 1999-03-16 | Terumo Corp | 腹膜透析液 |
AU2557899A (en) * | 1998-01-15 | 1999-08-02 | Edward Hirschberg | Methods of infusing phytochemicals, nutraceuticals, and other compositions into food products |
-
1999
- 1999-10-11 SK SK443-2002A patent/SK288072B6/sk not_active IP Right Cessation
- 1999-10-11 DE DE69932860T patent/DE69932860T2/de not_active Expired - Lifetime
- 1999-10-11 AT AT99954329T patent/ATE336243T1/de active
- 1999-10-11 SI SI9930921T patent/SI1220670T1/sl unknown
- 1999-10-11 EP EP99954329A patent/EP1220670B1/en not_active Expired - Lifetime
- 1999-10-11 CA CA2386826A patent/CA2386826C/en not_active Expired - Fee Related
- 1999-10-11 ES ES99954329T patent/ES2270620T3/es not_active Expired - Lifetime
- 1999-10-11 PL PL354414A patent/PL213131B1/pl unknown
- 1999-10-11 WO PCT/IT1999/000317 patent/WO2001026649A1/en active IP Right Grant
- 1999-10-11 CZ CZ20021063A patent/CZ303870B6/cs not_active IP Right Cessation
- 1999-10-11 MX MXPA02003635A patent/MXPA02003635A/es not_active IP Right Cessation
- 1999-10-11 DK DK99954329T patent/DK1220670T3/da active
- 1999-10-11 PT PT99954329T patent/PT1220670E/pt unknown
- 1999-10-11 KR KR1020027004552A patent/KR100642731B1/ko not_active IP Right Cessation
- 1999-10-11 US US10/110,304 patent/US6822002B1/en not_active Expired - Lifetime
- 1999-10-11 AU AU10734/00A patent/AU1073400A/en not_active Abandoned
- 1999-10-11 HU HU0203441A patent/HUP0203441A3/hu unknown
- 1999-10-11 JP JP2001529439A patent/JP4638106B2/ja not_active Expired - Fee Related
-
2002
- 2002-09-06 HK HK02106588.3A patent/HK1046090B/zh not_active IP Right Cessation
-
2004
- 2004-10-12 US US10/960,938 patent/US7932291B2/en not_active Expired - Fee Related
-
2006
- 2006-10-16 CY CY20061101485T patent/CY1106203T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
AU1073400A (en) | 2001-04-23 |
US7932291B2 (en) | 2011-04-26 |
PL354414A1 (en) | 2004-01-12 |
SK288072B6 (sk) | 2013-05-03 |
WO2001026649A1 (en) | 2001-04-19 |
HUP0203441A2 (hu) | 2003-03-28 |
MXPA02003635A (es) | 2002-10-23 |
HK1046090A1 (en) | 2002-12-27 |
PL213131B1 (pl) | 2013-01-31 |
EP1220670A1 (en) | 2002-07-10 |
EP1220670B1 (en) | 2006-08-16 |
JP2003511413A (ja) | 2003-03-25 |
ES2270620T3 (es) | 2007-04-01 |
KR20020038809A (ko) | 2002-05-23 |
US20050085542A1 (en) | 2005-04-21 |
DE69932860T2 (de) | 2007-08-30 |
ATE336243T1 (de) | 2006-09-15 |
JP4638106B2 (ja) | 2011-02-23 |
HUP0203441A3 (en) | 2004-01-28 |
DE69932860D1 (de) | 2006-09-28 |
SI1220670T1 (sl) | 2006-12-31 |
CZ303870B6 (cs) | 2013-06-05 |
HK1046090B (zh) | 2007-06-29 |
DK1220670T3 (da) | 2006-12-18 |
SK4432002A3 (en) | 2002-08-06 |
KR100642731B1 (ko) | 2006-11-03 |
PT1220670E (pt) | 2006-10-31 |
CZ20021063A3 (cs) | 2002-08-14 |
CA2386826C (en) | 2010-04-20 |
US6822002B1 (en) | 2004-11-23 |
CA2386826A1 (en) | 2001-04-19 |
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