IT1261695B - Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. - Google Patents
Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.Info
- Publication number
- IT1261695B IT1261695B ITRM930364A ITRM930364A IT1261695B IT 1261695 B IT1261695 B IT 1261695B IT RM930364 A ITRM930364 A IT RM930364A IT RM930364 A ITRM930364 A IT RM930364A IT 1261695 B IT1261695 B IT 1261695B
- Authority
- IT
- Italy
- Prior art keywords
- carnitine
- transfusions
- blood
- alcanoil
- preservation
- Prior art date
Links
- PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 title abstract 3
- 239000008280 blood Substances 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title abstract 2
- 230000000087 stabilizing effect Effects 0.000 title abstract 2
- 238000004321 preservation Methods 0.000 title 1
- -1 alkanoyl L-carnitine Chemical compound 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0205—Chemical aspects
- A01N1/021—Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
- A01N1/0226—Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Physiology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Vengono descritte soluzioni stabilizzatrici per la conservazione del sangue per trasfusioni, comprendenti L-carnitina, alcanoil L-carnitine o loro sali farmacologicamente accettabili.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM930364A IT1261695B (it) | 1993-06-02 | 1993-06-02 | Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. |
AT94830254T ATE170709T1 (de) | 1993-06-02 | 1994-05-26 | Verwendung von l-carnitin und alkanoyl l- carnitine zum bewahren von transfusionsblut, und sie enthaltenden stabilisierungslösungen |
EP94830254A EP0627161B1 (en) | 1993-06-02 | 1994-05-26 | Use of L-carnitine and alkanoyl L-carnitines in the storage of blood for transfusions and stabilizing solutions containing them |
DK94830254T DK0627161T3 (da) | 1993-06-02 | 1994-05-26 | Anvendelse af L-carnitin og alkanoyl L-carnitiner til opbevaring af blod til trandfusioner og stabiliserende opløsninger in |
ES94830254T ES2122214T3 (es) | 1993-06-02 | 1994-05-26 | Empleo de l-carnitina y alcanoil l-carnitinas en el almacenamiento de sangre para transfusiones y estabilizacion de soluciones que la contienen. |
DE69413120T DE69413120T2 (de) | 1993-06-02 | 1994-05-26 | Verwendung von L-Carnitin und Alkanoyl L-Carnitine zum Bewahren von Transfusionsblut, und sie enthaltenden Stabilisierungslösungen |
JP11993494A JP3573791B2 (ja) | 1993-06-02 | 1994-06-01 | L−カルニチン類を含む輸血用血液保存のための安定化溶液 |
US08/253,275 US5496821A (en) | 1993-06-02 | 1994-06-02 | Use of L-carnitine and alkanoyl L-carnitines in the storage of blood for transfusions and stabilizing solutions containing them |
US09/035,028 USRE36331E (en) | 1993-06-02 | 1998-03-05 | Use of L-carnitine and alkanoyl L-carnitines in the storage of blood for transfusions and stabilizing solutions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITRM930364A IT1261695B (it) | 1993-06-02 | 1993-06-02 | Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. |
Publications (3)
Publication Number | Publication Date |
---|---|
ITRM930364A0 ITRM930364A0 (it) | 1993-06-02 |
ITRM930364A1 ITRM930364A1 (it) | 1994-12-02 |
IT1261695B true IT1261695B (it) | 1996-05-29 |
Family
ID=11401790
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITRM930364A IT1261695B (it) | 1993-06-02 | 1993-06-02 | Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5496821A (it) |
EP (1) | EP0627161B1 (it) |
JP (1) | JP3573791B2 (it) |
AT (1) | ATE170709T1 (it) |
DE (1) | DE69413120T2 (it) |
DK (1) | DK0627161T3 (it) |
ES (1) | ES2122214T3 (it) |
IT (1) | IT1261695B (it) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6482585B2 (en) * | 1997-04-16 | 2002-11-19 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
US6403124B1 (en) * | 1997-04-16 | 2002-06-11 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Storage and maintenance of blood products including red blood cells and platelets |
ATE316757T1 (de) | 1998-05-26 | 2006-02-15 | Lifecell Corp | Cryokonservierung menschlicher roter blutzellen |
CZ303870B6 (cs) | 1999-10-11 | 2013-06-05 | Sigma-Tau Industrie Farmaceutiche Riunite S. P. A. | Vyuzití L-karnitinu a jeho alkanoylderivátu jako osmotických prostredku v roztocích pro medicinální vyuzití |
GB0001172D0 (en) * | 2000-01-20 | 2000-03-08 | Res Del International Limited | Physiological medium for perfusing, preserving and storing isolated cell tissue and organ samples |
ITRM20010337A1 (it) | 2001-06-14 | 2002-12-16 | Sigma Tau Ind Farmaceuti | Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati. |
WO2003097237A2 (en) * | 2002-05-13 | 2003-11-27 | Becton, Dickinson, And Company | Protease inhibitor sample collection system |
CA2501196A1 (en) * | 2002-10-10 | 2004-04-22 | Becton, Dickinson And Company | Sample collection system with caspase inhibitor |
EP1659862A2 (en) * | 2003-08-04 | 2006-05-31 | Human Biosystems | Preservation of blood cells |
US20050124965A1 (en) * | 2003-12-08 | 2005-06-09 | Becton, Dickinson And Company | Phosphatase inhibitor sample collection system |
US20050232911A1 (en) * | 2004-04-19 | 2005-10-20 | Schreiber Brian D | Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid |
ITRM20040346A1 (it) * | 2004-07-13 | 2004-10-13 | Sigma Tau Ind Farmaceuti | Uso della l-carnitina per il trattamento di patologie cardiovascolari. |
US8871434B2 (en) * | 2008-03-21 | 2014-10-28 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
US8968992B2 (en) * | 2008-03-21 | 2015-03-03 | Fenwal, Inc. | Red blood cell storage medium for extended storage |
WO2011049709A1 (en) | 2009-10-23 | 2011-04-28 | Fenwal, Inc. | Methods and systems for providing red blood cell products with reduced plasma |
JP5824950B2 (ja) * | 2011-08-08 | 2015-12-02 | ソニー株式会社 | 血液分析装置および血液分析方法 |
CN114786481A (zh) * | 2019-11-29 | 2022-07-22 | 新泽西鲁特格斯州立大学 | 用于储存血液制品的组合物、试剂盒和方法及其使用方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE639532A (it) * | ||||
DE2532183C3 (de) * | 1975-07-18 | 1982-03-04 | Behringwerke Ag, 3550 Marburg | Polyionische isotonische Salzlösung zur Konservierung von Erythrozyten oder zur Perfusion und zur Konservierung von zur Transplantion bestimmter Organen |
DE3026368A1 (de) * | 1980-07-11 | 1982-02-18 | Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München | Naehrloesung fuer die vollstaendige parenterale ernaehrung und fuer gesteigerte energieproduktion |
US4731360A (en) * | 1985-08-16 | 1988-03-15 | Merck & Co., Inc. | Acylcarnitines as absorption-enhancing agents for drug delivery through mucous membranes of the nasal, buccal, sublingual and vaginal compartments |
US4839159A (en) * | 1988-02-08 | 1989-06-13 | Topicarn, Inc. | Topical L-carnitine composition |
DE3905312A1 (de) * | 1989-02-21 | 1990-08-23 | Bayer Ag | Substituierte 3-amino-2-pyrazolin-5-on-derivate, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung von schaedlingen |
US4968719A (en) * | 1989-04-03 | 1990-11-06 | Sigma Tau, Industrie Farmaceutiche Riunite Spa | Method for treating vascular disease |
IT1245869B (it) * | 1991-06-05 | 1994-10-25 | Sigma Tau Ind Farmaceuti | Impiego di propionil l-carnitina per il recupero del tono muscolare in soggetti immobilizzati |
-
1993
- 1993-06-02 IT ITRM930364A patent/IT1261695B/it active IP Right Grant
-
1994
- 1994-05-26 ES ES94830254T patent/ES2122214T3/es not_active Expired - Lifetime
- 1994-05-26 DE DE69413120T patent/DE69413120T2/de not_active Expired - Lifetime
- 1994-05-26 DK DK94830254T patent/DK0627161T3/da active
- 1994-05-26 EP EP94830254A patent/EP0627161B1/en not_active Expired - Lifetime
- 1994-05-26 AT AT94830254T patent/ATE170709T1/de active
- 1994-06-01 JP JP11993494A patent/JP3573791B2/ja not_active Expired - Fee Related
- 1994-06-02 US US08/253,275 patent/US5496821A/en not_active Ceased
-
1998
- 1998-03-05 US US09/035,028 patent/USRE36331E/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5496821A (en) | 1996-03-05 |
JP3573791B2 (ja) | 2004-10-06 |
JPH0748329A (ja) | 1995-02-21 |
DE69413120T2 (de) | 1999-02-11 |
ITRM930364A0 (it) | 1993-06-02 |
DE69413120D1 (de) | 1998-10-15 |
DK0627161T3 (da) | 1999-06-07 |
ES2122214T3 (es) | 1998-12-16 |
ITRM930364A1 (it) | 1994-12-02 |
EP0627161A1 (en) | 1994-12-07 |
ATE170709T1 (de) | 1998-09-15 |
USRE36331E (en) | 1999-10-05 |
EP0627161B1 (en) | 1998-09-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970515 |