DK1220670T3 - Anvendelse af L-carnitin og dets alkanoylderivater som osmotiske stoffer i oplösninger til medicinsk anvendelse - Google Patents

Anvendelse af L-carnitin og dets alkanoylderivater som osmotiske stoffer i oplösninger til medicinsk anvendelse

Info

Publication number
DK1220670T3
DK1220670T3 DK99954329T DK99954329T DK1220670T3 DK 1220670 T3 DK1220670 T3 DK 1220670T3 DK 99954329 T DK99954329 T DK 99954329T DK 99954329 T DK99954329 T DK 99954329T DK 1220670 T3 DK1220670 T3 DK 1220670T3
Authority
DK
Denmark
Prior art keywords
carnitine
solutions
alkanoyl derivatives
osmotic substances
medical use
Prior art date
Application number
DK99954329T
Other languages
Danish (da)
English (en)
Inventor
Arduino Arduini
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK1220670T3 publication Critical patent/DK1220670T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Urology & Nephrology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • External Artificial Organs (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK99954329T 1999-10-11 1999-10-11 Anvendelse af L-carnitin og dets alkanoylderivater som osmotiske stoffer i oplösninger til medicinsk anvendelse DK1220670T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IT1999/000317 WO2001026649A1 (fr) 1999-10-11 1999-10-11 Utilisation de la l-carnitine et de ses derives alkanoyles comme agents osmotiques dans des solutions a usage medical

Publications (1)

Publication Number Publication Date
DK1220670T3 true DK1220670T3 (da) 2006-12-18

Family

ID=11333127

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99954329T DK1220670T3 (da) 1999-10-11 1999-10-11 Anvendelse af L-carnitin og dets alkanoylderivater som osmotiske stoffer i oplösninger til medicinsk anvendelse

Country Status (20)

Country Link
US (2) US6822002B1 (fr)
EP (1) EP1220670B1 (fr)
JP (1) JP4638106B2 (fr)
KR (1) KR100642731B1 (fr)
AT (1) ATE336243T1 (fr)
AU (1) AU1073400A (fr)
CA (1) CA2386826C (fr)
CY (1) CY1106203T1 (fr)
CZ (1) CZ303870B6 (fr)
DE (1) DE69932860T2 (fr)
DK (1) DK1220670T3 (fr)
ES (1) ES2270620T3 (fr)
HK (1) HK1046090B (fr)
HU (1) HUP0203441A3 (fr)
MX (1) MXPA02003635A (fr)
PL (1) PL213131B1 (fr)
PT (1) PT1220670E (fr)
SI (1) SI1220670T1 (fr)
SK (1) SK288072B6 (fr)
WO (1) WO2001026649A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770148B1 (en) 1998-12-04 2004-08-03 Baxter International Inc. Peritoneal dialysis solution containing modified icodextrins
ITRM20010337A1 (it) * 2001-06-14 2002-12-16 Sigma Tau Ind Farmaceuti Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
US8173618B2 (en) * 2003-07-25 2012-05-08 University Of Massachusetts Formulations for reducing neuronal degeneration
US7053059B2 (en) 2003-07-25 2006-05-30 Baxter International Inc. Dialysis solutions with reduced levels of glucose degradation products
ITRM20040346A1 (it) 2004-07-13 2004-10-13 Sigma Tau Ind Farmaceuti Uso della l-carnitina per il trattamento di patologie cardiovascolari.
JP2006075195A (ja) * 2004-09-07 2006-03-23 Jms Co Ltd Lカルニチン含有腹膜透析液
TWI388318B (zh) * 2005-03-10 2013-03-11 Sigma Tau Ind Farmaceuti 具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液
US20070087975A1 (en) * 2005-10-17 2007-04-19 Sigma-Tau Industrie Farmaceutiche Riunite Spa Compound useful for the prevention and treatment of left ventricular hypertrophy in dialysed patients
RU2426561C2 (ru) * 2006-01-30 2011-08-20 Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния Способы и устройство для перитонеального диализа
US8876753B2 (en) 2006-01-30 2014-11-04 The Regents Of The University Of California Peritoneal dialysis methods and apparatus
US8597640B2 (en) * 2007-10-31 2013-12-03 University Of Massachusetts Lowell Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging
ES2396650B2 (es) * 2011-07-21 2013-07-16 Universidad Complutense De Madrid Uso de una composición en la elaboración de una solución de diálisis para el tratamiento de las enfermedades cerebrovasculares mediante diálisis peritoneal.
TWI454287B (zh) * 2012-11-21 2014-10-01 Taipei Veteran General Hospital 治療纖維化之透析液
US9539411B2 (en) 2013-03-13 2017-01-10 W. L. Gore & Associates, Inc. Deconstructable endoluminal devices and related systems and methods
CN103330715B (zh) * 2013-07-01 2015-09-02 华仁药业股份有限公司 一种抗腹膜纤维化的腹膜透析液
CN103463081B (zh) * 2013-09-27 2015-10-21 华仁药业股份有限公司 腹膜透析液
DE102015014699A1 (de) * 2015-11-13 2017-05-18 Fresenius Medical Care Deutschland Gmbh Dialyselösung mit wenigstens einem Osmotikum
EP3912656A1 (fr) 2020-05-19 2021-11-24 CoreQuest Sagl Solution de dialyse péritonéale
EP4029507A1 (fr) 2021-01-19 2022-07-20 Iperboreal Pharma Srl Solution de dialyse péritonéale pour sujets hypertensifs

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1156741B (it) 1978-05-15 1987-02-04 Sigma Tau Ind Farmaceuti Applicazione terapeutica della carnitina e di alcuni derivati acilati della carnitina nell'emodialisi
IT1120033B (it) * 1979-10-05 1986-03-19 Sigma Tau Ind Farmaceuti Composizione farmaceutica comprendente-carnitina adatta per l'alimentazione parenterale
CH664374A5 (de) * 1985-02-27 1988-02-29 Lonza Ag Verfahren zur herstellung von l-carnitin auf mikrobiologischem weg.
JPH04320145A (ja) * 1991-04-19 1992-11-10 Ricoh Co Ltd ファクシミリ装置
IT1261695B (it) 1993-06-02 1996-05-29 Sigma Tau Ind Farmaceuti Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
IT1283137B1 (it) 1996-07-09 1998-04-07 Bieffe Medital Spa Agenti osmotici alternativi e relative soluzioni per dialisi peritoneale
JPH1094598A (ja) 1996-07-31 1998-04-14 Baxter Internatl Inc 腹膜透析液
US5973004A (en) * 1997-04-04 1999-10-26 Howard; James R. L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism
US6482585B2 (en) * 1997-04-16 2002-11-19 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
GB9714218D0 (en) 1997-07-04 1997-09-10 Allied Therapeutics Ltd Peritoneal dialysis fluid
JPH1149671A (ja) 1997-08-06 1999-02-23 Baxter Internatl Inc 腹膜透析液
US6537976B1 (en) * 1997-08-07 2003-03-25 Ajay Gupta Dialysis solutions containing water soluble vitamins and nutrients
JPH1171286A (ja) 1997-08-29 1999-03-16 Terumo Corp 腹膜透析液
JPH1171273A (ja) 1997-08-29 1999-03-16 Terumo Corp 腹膜透析液
WO1999035917A1 (fr) * 1998-01-15 1999-07-22 Edward Hirschberg Procedes d'infusion de substances phytochimiques, d'aliments fonctionnels et d'autres compositions dans des produits alimentaires

Also Published As

Publication number Publication date
US7932291B2 (en) 2011-04-26
CZ303870B6 (cs) 2013-06-05
SI1220670T1 (sl) 2006-12-31
KR100642731B1 (ko) 2006-11-03
MXPA02003635A (es) 2002-10-23
JP2003511413A (ja) 2003-03-25
CA2386826A1 (fr) 2001-04-19
CZ20021063A3 (cs) 2002-08-14
EP1220670A1 (fr) 2002-07-10
SK4432002A3 (en) 2002-08-06
HK1046090A1 (en) 2002-12-27
DE69932860D1 (de) 2006-09-28
WO2001026649A1 (fr) 2001-04-19
AU1073400A (en) 2001-04-23
HUP0203441A3 (en) 2004-01-28
EP1220670B1 (fr) 2006-08-16
US20050085542A1 (en) 2005-04-21
JP4638106B2 (ja) 2011-02-23
SK288072B6 (sk) 2013-05-03
KR20020038809A (ko) 2002-05-23
PL213131B1 (pl) 2013-01-31
CA2386826C (fr) 2010-04-20
DE69932860T2 (de) 2007-08-30
PL354414A1 (en) 2004-01-12
US6822002B1 (en) 2004-11-23
HUP0203441A2 (hu) 2003-03-28
HK1046090B (zh) 2007-06-29
CY1106203T1 (el) 2011-06-08
PT1220670E (pt) 2006-10-31
ATE336243T1 (de) 2006-09-15
ES2270620T3 (es) 2007-04-01

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