DK1033990T3 - 21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud - Google Patents

21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud

Info

Publication number
DK1033990T3
DK1033990T3 DK98956833T DK98956833T DK1033990T3 DK 1033990 T3 DK1033990 T3 DK 1033990T3 DK 98956833 T DK98956833 T DK 98956833T DK 98956833 T DK98956833 T DK 98956833T DK 1033990 T3 DK1033990 T3 DK 1033990T3
Authority
DK
Denmark
Prior art keywords
oxidoprogesterone
hydroxy
drug
treatment
glucocorticoid excess
Prior art date
Application number
DK98956833T
Other languages
English (en)
Inventor
Gerardo Burton
Carlos Pedro Lantos
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of DK1033990T3 publication Critical patent/DK1033990T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/46—Drugs for disorders of the endocrine system of the suprarenal hormones for decreasing, blocking or antagonising the activity of glucocorticosteroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98956833T 1997-09-23 1998-09-22 21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud DK1033990T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97116526A EP0903146A1 (en) 1997-09-23 1997-09-23 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid
PCT/EP1998/006021 WO1999015181A1 (en) 1997-09-23 1998-09-22 21-hydroxy-6,19-oxidoprogesterone (21oh-6op) and its use as medicament for treating excess of glucocorticoids

Publications (1)

Publication Number Publication Date
DK1033990T3 true DK1033990T3 (da) 2002-07-08

Family

ID=8227390

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98956833T DK1033990T3 (da) 1997-09-23 1998-09-22 21-Hydroxy-6,19-oxidoprogesteron (21OH-6OP) dets anvendelse som medikament i behandling af glucocorticoidoverskud

Country Status (13)

Country Link
US (1) US6303591B1 (da)
EP (2) EP0903146A1 (da)
AR (1) AR023008A1 (da)
AT (1) ATE215373T1 (da)
AU (1) AU738522B2 (da)
CA (1) CA2303817C (da)
DE (1) DE69804659T2 (da)
DK (1) DK1033990T3 (da)
ES (1) ES2172937T3 (da)
IL (1) IL135232A (da)
PT (1) PT1033990E (da)
WO (1) WO1999015181A1 (da)
ZA (1) ZA988674B (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU776608B2 (en) 1999-04-30 2004-09-16 Pfizer Products Inc. Glucocorticoid receptor modulators
US7713989B2 (en) 2000-04-27 2010-05-11 Dow Robert L Glucocorticoid receptor modulators
PT1325022E (pt) * 2000-09-18 2006-12-29 Applied Research Systems Método para a preparação de 21-hidroxi-6, 19-oxido-progesterona (210h-60p)
EP1330468B1 (en) * 2000-09-18 2007-08-01 Applied Research Systems ARS Holding N.V. Sulphur analogues of 21-hydroxy-6,19-oxidoprogesterone (21oh-6op) for treating excess of glucocorticoids
EP1201660B1 (en) 2000-10-30 2005-08-31 Pfizer Products Inc. Glucocorticoid receptor modulators
US8097606B2 (en) * 2003-07-23 2012-01-17 Corcept Therapeutics, Inc. Antiglucocorticoids for the treatment of catatonia
EP1886695A1 (en) * 2006-06-27 2008-02-13 Speedel Experimenta AG Pharmaceutical combination of an aldosterone synthase inhibitor and a glucocorticoid receptor antagonist or a cortisol synthesis inhibitor or a corticotropin releasing factor antagonist
CN107007581A (zh) 2006-08-24 2017-08-04 田纳西大学研究基金会 取代的n‑酰基苯胺及其使用方法
ES2762243T3 (es) 2010-05-26 2020-05-22 Corcept Therapeutics Inc Tratamiento de distrofia muscular
US10314807B2 (en) 2012-07-13 2019-06-11 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
PT2872482T (pt) 2012-07-13 2020-09-22 Oncternal Therapeutics Inc Método de tratamento de cancro de mama com modulador seletivo do recetor de andrógeno (sarm)
US9744149B2 (en) 2012-07-13 2017-08-29 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10258596B2 (en) 2012-07-13 2019-04-16 Gtx, Inc. Method of treating HER2-positive breast cancers with selective androgen receptor modulators (SARMS)
US9622992B2 (en) 2012-07-13 2017-04-18 Gtx, Inc. Method of treating androgen receptor (AR)-positive breast cancers with selective androgen receptor modulator (SARMs)
US10987334B2 (en) 2012-07-13 2021-04-27 University Of Tennessee Research Foundation Method of treating ER mutant expressing breast cancers with selective androgen receptor modulators (SARMs)
US9969683B2 (en) 2012-07-13 2018-05-15 Gtx, Inc. Method of treating estrogen receptor (ER)-positive breast cancers with selective androgen receptor modulator (SARMS)
CA2977591A1 (en) 2015-03-02 2016-09-09 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonist and somatostatin analogues to treat acth-secreting tumors
ES2906778T3 (es) 2015-03-30 2022-04-20 Corcept Therapeutics Inc Uso de antagonistas del receptor de glucocorticoides en combinación con glucocorticoides para tratar la insuficiencia suprarrenal
MX2018001803A (es) 2015-08-13 2018-05-16 Corcept Therapeutics Inc Metodo para disgnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina.
JP6765443B2 (ja) 2016-01-19 2020-10-07 コーセプト セラピューティクス， インコーポレイテッド 異所性クッシング症候群の鑑別診断
WO2018236749A2 (en) 2017-06-20 2018-12-27 Corcept Therapeutics, Inc. METHODS OF TREATING NEURO-EPITHELIAL TUMORS USING GLUCOCORTICOID RECEPTOR SELECTIVE MODULATORS
CN113645979A (zh) * 2018-12-28 2021-11-12 熊猫咨询有限责任公司 短效选择性糖皮质激素受体调节剂

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
CN1919199A (zh) * 1997-10-06 2007-02-28 利兰·斯坦福青年大学托管委员会 治疗糖皮质素功能失调相关性精神病的方法

Also Published As

Publication number Publication date
AR023008A1 (es) 2002-09-04
WO1999015181A1 (en) 1999-04-01
IL135232A (en) 2005-05-17
IL135232A0 (en) 2001-05-20
US6303591B1 (en) 2001-10-16
DE69804659T2 (de) 2002-10-02
AU738522B2 (en) 2001-09-20
ZA988674B (en) 1999-06-28
CA2303817C (en) 2008-04-01
AU1334199A (en) 1999-04-12
EP1033990B1 (en) 2002-04-03
DE69804659D1 (de) 2002-05-08
EP0903146A1 (en) 1999-03-24
ES2172937T3 (es) 2002-10-01
CA2303817A1 (en) 1999-04-01
EP1033990A1 (en) 2000-09-13
ATE215373T1 (de) 2002-04-15
PT1033990E (pt) 2002-07-31

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