SK284171B6 - Derivát 4''-substituovaného-9-deoxo-9a-aza-9a-homoerytromycínu A, spôsob a medziprodukty na jeho prípravu, jeho použitie a farmaceutická kompozícia s jeho obsahom - Google Patents

Derivát 4''-substituovaného-9-deoxo-9a-aza-9a-homoerytromycínu A, spôsob a medziprodukty na jeho prípravu, jeho použitie a farmaceutická kompozícia s jeho obsahom Download PDF

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Publication number
SK284171B6
SK284171B6 SK1683-99A SK168399A SK284171B6 SK 284171 B6 SK284171 B6 SK 284171B6 SK 168399 A SK168399 A SK 168399A SK 284171 B6 SK284171 B6 SK 284171B6
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SK
Slovakia
Prior art keywords
compound
formula
hydroxy
hydrogen
groups
Prior art date
Application number
SK1683-99A
Other languages
English (en)
Slovak (sk)
Other versions
SK168399A3 (en
Inventor
Brian Scott Bronk
Michael Anthony Letavic
Takushi Kaneko
Bingwei Vera Yang
Edward Alan Glazer
Hengmiao Cheng
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21959336&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SK284171(B6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of SK168399A3 publication Critical patent/SK168399A3/sk
Publication of SK284171B6 publication Critical patent/SK284171B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SK1683-99A 1997-06-11 1998-05-29 Derivát 4''-substituovaného-9-deoxo-9a-aza-9a-homoerytromycínu A, spôsob a medziprodukty na jeho prípravu, jeho použitie a farmaceutická kompozícia s jeho obsahom SK284171B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4934897P 1997-06-11 1997-06-11
PCT/IB1998/000839 WO1998056802A1 (en) 1997-06-11 1998-05-29 4'-substituted-9-deoxo-9a-aza-9a-homoerythromycin a derivatives

Publications (2)

Publication Number Publication Date
SK168399A3 SK168399A3 (en) 2000-11-07
SK284171B6 true SK284171B6 (sk) 2004-10-05

Family

ID=21959336

Family Applications (1)

Application Number Title Priority Date Filing Date
SK1683-99A SK284171B6 (sk) 1997-06-11 1998-05-29 Derivát 4''-substituovaného-9-deoxo-9a-aza-9a-homoerytromycínu A, spôsob a medziprodukty na jeho prípravu, jeho použitie a farmaceutická kompozícia s jeho obsahom

Country Status (50)

Country Link
US (4) US6420536B1 (uk)
EP (1) EP0988310B9 (uk)
JP (2) JP3315704B2 (uk)
KR (1) KR100396168B1 (uk)
CN (4) CN1793155B (uk)
AP (1) AP1231A (uk)
AR (1) AR013086A1 (uk)
AT (1) ATE251173T1 (uk)
AU (1) AU749816B2 (uk)
BG (1) BG64391B1 (uk)
BR (1) BRPI9810519B8 (uk)
CA (1) CA2293823C (uk)
CO (1) CO4950611A1 (uk)
CZ (1) CZ298556B6 (uk)
DE (2) DE122004000018I2 (uk)
DK (1) DK0988310T3 (uk)
DZ (1) DZ2514A1 (uk)
EA (1) EA002441B1 (uk)
EG (1) EG24081A (uk)
ES (1) ES2205487T3 (uk)
FR (1) FR04C0013I2 (uk)
GT (1) GT199800077A (uk)
HK (3) HK1028048A1 (uk)
HN (1) HN1998000086A (uk)
HR (1) HRP980314B1 (uk)
HU (2) HU228005B1 (uk)
ID (1) ID22992A (uk)
IL (1) IL132809A0 (uk)
IS (1) IS1998B (uk)
LU (1) LU91076I9 (uk)
MA (1) MA24564A1 (uk)
ME (1) ME00876B (uk)
MY (1) MY123354A (uk)
NL (1) NL300150I2 (uk)
NO (1) NO316911B1 (uk)
NZ (2) NZ514871A (uk)
OA (1) OA11224A (uk)
PA (1) PA8452201A1 (uk)
PE (1) PE79699A1 (uk)
PL (1) PL191601B1 (uk)
PT (1) PT988310E (uk)
RS (1) RS49675B (uk)
SI (1) SI0988310T1 (uk)
SK (1) SK284171B6 (uk)
TN (1) TNSN98082A1 (uk)
TW (1) TW472060B (uk)
UA (1) UA67744C2 (uk)
UY (1) UY25040A1 (uk)
WO (1) WO1998056802A1 (uk)
ZA (1) ZA985017B (uk)

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US6043227A (en) * 1998-08-19 2000-03-28 Pfizer Inc. C11 carbamates of macrolide antibacterials
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US6100240A (en) * 1998-10-09 2000-08-08 Pfizer Inc Macrolide derivatives
CA2292359C (en) * 1999-01-28 2004-09-28 Pfizer Products Inc. Novel azalides and methods of making same
BR0011300A (pt) * 1999-05-18 2002-02-26 Pfizer Prod Inc Formas cristalinas de um antibiótico macrólido
EA200100983A1 (ru) * 1999-05-24 2002-10-31 Пфайзер Продактс Инк. Производные 13-метилэритромицина
US6465437B1 (en) * 1999-06-30 2002-10-15 Pfizer Inc. Diphosphate salt of a 4″-substituted-9-deoxo-9A-AZA-9A- homoerythromycin derivative and its pharmaceutical composition
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ATE315042T1 (de) * 1999-08-24 2006-02-15 Abbott Lab 9a-azalide mit antibakterieller wirkung
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AU2002317415A1 (en) * 2001-08-01 2003-02-17 Pfizer Products Inc. Azalide antibiotic compositions
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US7402568B2 (en) 2004-09-29 2008-07-22 Enanta Pharmaceuticals, Inc. Bicyclic 9a-azalide derivatives
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CN101917850B (zh) * 2007-10-25 2016-01-13 森普拉制药公司 大环内酯类抗菌剂的制备方法
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RU2650883C2 (ru) 2010-03-22 2018-04-18 Семпра Фармасьютикалз, Инк. Кристаллические формы макролида и их применение
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CN102260306B (zh) * 2011-07-22 2012-07-18 山东鲁抗舍里乐药业有限公司 一种制备泰拉霉素的方法
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CN102786569B (zh) * 2012-09-07 2016-12-07 安徽中升药业有限公司 泰拉霉素中间体及其制备方法与泰拉霉素的制备方法
AU2014239959A1 (en) 2013-03-14 2015-10-01 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
JP6675973B2 (ja) 2013-03-15 2020-04-08 センプラ ファーマシューティカルズ，インコーポレイテッド マクロライド抗菌薬を調製するための集束的な方法
WO2015014907A1 (en) * 2013-07-31 2015-02-05 Farma Grs, D.O.O. Process for preparation of tulathromycin
CN103497227B (zh) * 2013-09-13 2015-09-30 青岛科技大学 一种泰拉菌素中间体的制备方法
CN104725446B (zh) * 2015-03-26 2017-10-27 宁夏泰瑞制药股份有限公司 一种从泰拉霉素粗品中分离泰拉霉素a和泰拉霉素b的方法
CN104861018A (zh) * 2015-06-17 2015-08-26 瑞普（天津）生物药业有限公司 一种泰拉菌素的制备方法
CN105646617A (zh) * 2016-01-21 2016-06-08 杭州海尔希畜牧科技有限公司 一种制备泰拉霉素的方法
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Also Published As

Publication number Publication date
CZ442199A3 (cs) 2000-07-12
WO1998056802A1 (en) 1998-12-17
ES2205487T3 (es) 2004-05-01
AU749816B2 (en) 2002-07-04
LU91076I9 (en) 2018-07-02
CZ298556B6 (cs) 2007-11-07
RS49675B (sr) 2007-11-15
PL337505A1 (en) 2000-08-28
JP3315704B2 (ja) 2002-08-19
JP2002316933A (ja) 2002-10-31
GT199800077A (es) 1999-12-02
ATE251173T1 (de) 2003-10-15
FR04C0013I1 (uk) 2004-06-11
US6420536B1 (en) 2002-07-16
HUP0002209A2 (hu) 2000-12-28
DE122004000018I1 (de) 2004-09-30
MY123354A (en) 2006-05-31
KR20010013632A (ko) 2001-02-26
HK1088014A1 (en) 2006-10-27
NZ514871A (en) 2003-08-29
ZA985017B (en) 1999-12-17
UA67744C2 (uk) 2004-07-15
TW472060B (en) 2002-01-11
PT988310E (pt) 2003-12-31
BRPI9810519A (pt) 2000-09-19
HRP980314B1 (en) 2004-04-30
SI0988310T1 (en) 2004-02-29
BRPI9810519B8 (pt) 2022-11-16
PA8452201A1 (es) 2000-05-24
HUS1200028I1 (hu) 2016-08-29
HU228005B1 (en) 2012-08-28
CN1566129A (zh) 2005-01-19
HN1998000086A (es) 1999-03-08
US20040023896A1 (en) 2004-02-05
BG64391B1 (bg) 2004-12-30
HK1068893A1 (en) 2005-07-29
MA24564A1 (fr) 1998-12-31
EG24081A (en) 2008-05-11
CN1793155B (zh) 2010-05-12
US20040180842A1 (en) 2004-09-16
EP0988310B1 (en) 2003-10-01
CN1259136A (zh) 2000-07-05
IS1998B (is) 2005-03-15
IS5252A (is) 1999-11-16
DE69818665D1 (de) 2003-11-06
BRPI9810519B1 (pt) 2012-02-22
SK168399A3 (en) 2000-11-07
CA2293823C (en) 2004-02-17
NL300150I1 (nl) 2004-08-02
DE69818665T2 (de) 2004-04-29
UY25040A1 (es) 2000-09-29
AP9801255A0 (en) 1998-06-30
NO996106L (no) 2000-02-10
CA2293823A1 (en) 1998-12-17
CN1243766C (zh) 2006-03-01
YU58699A (uk) 2002-08-12
CO4950611A1 (es) 2000-09-01
NO996106D0 (no) 1999-12-10
EA002441B1 (ru) 2002-04-25
EA199901015A1 (ru) 2000-06-26
AP1231A (en) 2003-12-11
CN101691390A (zh) 2010-04-07
CN1172947C (zh) 2004-10-27
OA11224A (en) 2003-07-16
US6777393B2 (en) 2004-08-17
CN1793155A (zh) 2006-06-28
DE122004000018I2 (de) 2011-01-13
DZ2514A1 (fr) 2003-02-01
EP0988310A1 (en) 2000-03-29
HUP0002209A3 (en) 2003-05-28
NZ500660A (en) 2002-03-01
DK0988310T3 (da) 2003-12-15
AR013086A1 (es) 2000-12-13
EP0988310B9 (en) 2006-03-08
TNSN98082A1 (fr) 2005-03-15
HK1028048A1 (en) 2001-02-02
US6936592B2 (en) 2005-08-30
PL191601B1 (pl) 2006-06-30
NL300150I2 (nl) 2004-09-01
ME00876B (me) 2012-06-20
ID22992A (id) 1999-12-23
BG103945A (en) 2000-07-31
US20020061858A1 (en) 2002-05-23
FR04C0013I2 (uk) 2005-10-21
HRP980314A2 (en) 1999-04-30
LU91076I2 (fr) 2004-07-05
NO316911B1 (no) 2004-06-21
KR100396168B1 (ko) 2003-08-27
PE79699A1 (es) 1999-08-25
AU7347598A (en) 1998-12-30
IL132809A0 (en) 2001-03-19
JP2000514098A (ja) 2000-10-24

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