SI3098234T1 - Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo - Google Patents

Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo

Info

Publication number
SI3098234T1
SI3098234T1 SI200932205T SI200932205T SI3098234T1 SI 3098234 T1 SI3098234 T1 SI 3098234T1 SI 200932205 T SI200932205 T SI 200932205T SI 200932205 T SI200932205 T SI 200932205T SI 3098234 T1 SI3098234 T1 SI 3098234T1
Authority
SI
Slovenia
Prior art keywords
alpha
sialylation
recombinant fsh
fsh including
including alpha
Prior art date
Application number
SI200932205T
Other languages
English (en)
Slovenian (sl)
Inventor
Ian Cottingham
Daniel Plaksin
Richard Boyd White
Original Assignee
Ferring B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39717519&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI3098234(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ferring B.V. filed Critical Ferring B.V.
Publication of SI3098234T1 publication Critical patent/SI3098234T1/sl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/24Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/06Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1048Glycosyltransferases (2.4)
    • C12N9/1081Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/99Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y204/00Glycosyltransferases (2.4)
    • C12Y204/99Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • C12Y204/99006N-Acetyllactosaminide alpha-2,3-sialyltransferase (2.4.99.6)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Reproductive Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
SI200932205T 2008-04-16 2009-04-16 Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo SI3098234T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4542408P 2008-04-16 2008-04-16
EP08251528 2008-04-25
EP16179121.5A EP3098234B1 (en) 2008-04-16 2009-04-16 Recombinant fsh including alpha 2,3- and alpha 2,6-sialylation

Publications (1)

Publication Number Publication Date
SI3098234T1 true SI3098234T1 (sl) 2024-10-30

Family

ID=39717519

Family Applications (6)

Application Number Title Priority Date Filing Date
SI200932205T SI3098234T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH,ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200930931T SI2268666T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931670A SI3045471T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo
SI200932094T SI3144318T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932209T SI4015527T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931547A SI2808340T1 (sl) 2008-04-16 2009-04-16 Rekombinirani FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo

Family Applications After (5)

Application Number Title Priority Date Filing Date
SI200930931T SI2268666T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931670A SI3045471T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3 in alfa 2,6-sialilacijo
SI200932094T SI3144318T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vsebuje alfa 2,3- in alfa 2,6-sialilacijo
SI200932209T SI4015527T1 (sl) 2008-04-16 2009-04-16 Rekombinantni FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo
SI200931547A SI2808340T1 (sl) 2008-04-16 2009-04-16 Rekombinirani FSH, ki vključuje alfa 2,3- in alfa 2,6-sialilacijo

Country Status (29)

Country Link
US (6) US8951967B2 (enExample)
EP (7) EP2268666B1 (enExample)
JP (7) JP2011519359A (enExample)
KR (5) KR20170110741A (enExample)
CN (3) CN102066414A (enExample)
AR (1) AR071479A1 (enExample)
AU (5) AU2009237479B2 (enExample)
BR (1) BRPI0910461B8 (enExample)
CA (1) CA2725257A1 (enExample)
CY (1) CY1115413T1 (enExample)
DK (6) DK2268666T3 (enExample)
ES (5) ES3023526T3 (enExample)
FI (4) FI4015527T3 (enExample)
FR (3) FR17C1020I2 (enExample)
HR (5) HRP20250313T1 (enExample)
HU (9) HUE071059T2 (enExample)
IL (2) IL208538A (enExample)
LT (8) LT3098234T (enExample)
MX (3) MX2010011343A (enExample)
NO (4) NO2017025I1 (enExample)
NZ (1) NZ588381A (enExample)
PL (6) PL3144318T3 (enExample)
PT (6) PT3144318T (enExample)
RU (3) RU2537268C2 (enExample)
SA (1) SA109300228B1 (enExample)
SI (6) SI3098234T1 (enExample)
TW (1) TWI488640B (enExample)
WO (1) WO2009127826A1 (enExample)
ZA (1) ZA201007373B (enExample)

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JP5918697B2 (ja) 2010-10-15 2016-05-18 Jcrファーマ株式会社 糖鎖の非還元末端がマンノース残基である糖蛋白質の製造方法
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WO2012168680A1 (en) 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) * 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
AU2012340501A1 (en) * 2011-12-19 2013-07-11 Grifols, S.A. Compositions, methods, and kits for preparing sialylated recombinant proteins
WO2013161958A1 (ja) * 2012-04-27 2013-10-31 日本ケミカルリサーチ株式会社 新規な発現ベクター
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JP6652334B2 (ja) 2014-05-31 2020-02-19 Jcrファーマ株式会社 ウリジンとn−アセチル−d−マンノサミンとを含有する培地
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ES2784625T3 (es) 2015-04-17 2020-09-29 Ferring Bv FSH para el tratamiento de la infertilidad
JP6845813B2 (ja) 2015-06-26 2021-03-24 フェリング ベスローテン フェンノートシャップ 精製および/またはウイルス不活性化の方法
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EP3441471A1 (en) 2017-08-08 2019-02-13 CEVEC Pharmaceuticals GmbH Use of constitutively active variants of growth factor receptors as selection makers for the generation of stable producer cell lines
EP4427806A3 (en) 2017-09-01 2024-10-09 Ferring B.V. Composition for controlled ovarian stimulation
SI3787667T1 (sl) 2018-04-30 2025-06-30 Ferring B.V. Sestavek za nadzorovano stimulacijo jajčnikov
TWI846743B (zh) 2018-10-17 2024-07-01 荷蘭商菲林公司 用於控制性卵巢刺激之組成物及方法
US20220380785A1 (en) * 2019-11-01 2022-12-01 The University Of British Columbia Compositions and methods for sialylated mucin-type o-glycosylation of therapeutic proteins
TW202237173A (zh) 2020-12-09 2022-10-01 荷蘭商菲林公司 用於受控的卵巢刺激之組成物及方法
US20250241993A1 (en) 2022-04-01 2025-07-31 Ferring B.V. Mixed protocol for treatment of infertility
EP4531895A1 (en) 2022-05-26 2025-04-09 Ferring B.V. Compositions and methods for treatment of infertility in males
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CA2831486A1 (en) 2011-03-31 2012-10-04 Ferring B.V. Pharmaceutical preparation
WO2012168680A1 (en) 2011-06-06 2012-12-13 Ferring B.V. Pharmaceutical preparation comprising recombinant fsh
JO3092B1 (ar) 2011-08-08 2017-03-15 Ferring Bv مركب لتحفيز مسيطر عليه للمبيض
SG11201608132UA (en) 2014-04-18 2016-11-29 Glycotope Gmbh Controlled ovarian hyperstimulation with improved recombinant human follicle-stimulating hormone

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ES2468318T3 (es) 2014-06-16
LT2808340T (lt) 2016-11-10
US8951967B2 (en) 2015-02-10
NO2025006I1 (no) 2025-01-16
CY1115413T1 (el) 2017-01-04
JP6762916B2 (ja) 2020-09-30
IL208538A (en) 2014-03-31
IL230571A (en) 2015-11-30
ZA201007373B (en) 2011-06-29
RU2537268C2 (ru) 2014-12-27
NO2025032I1 (no) 2025-07-14
US20150065695A1 (en) 2015-03-05
RU2010141908A (ru) 2012-05-27
JP2020040956A (ja) 2020-03-19
AU2017225020B2 (en) 2019-11-14
AU2017204259B2 (en) 2017-08-17
SI3045471T1 (sl) 2017-07-31
US20160347811A1 (en) 2016-12-01
HUS1700036I1 (hu) 2017-10-30
JP2011519359A (ja) 2011-07-07
HRP20161520T1 (hr) 2016-12-30
DK2268666T3 (da) 2014-05-12
HUE068565T2 (hu) 2025-01-28
EP2268666B1 (en) 2014-03-12
RU2682270C2 (ru) 2019-03-18
US11952407B2 (en) 2024-04-09
AU2014203277B2 (en) 2017-04-06
FIC20250003I1 (fi) 2025-01-15
KR102108377B1 (ko) 2020-05-08
EP2808340A1 (en) 2014-12-03
DK4015527T3 (da) 2025-04-14
IL208538A0 (en) 2010-12-30
JP7316905B2 (ja) 2023-07-28
PT3045471T (pt) 2017-06-14
FR25C1003I1 (fr) 2025-02-28
HUE030652T4 (en) 2017-09-28
ES3023526T3 (en) 2025-06-02
DK2808340T3 (en) 2016-12-05
JP2018021037A (ja) 2018-02-08
FR17C1020I1 (enExample) 2020-04-10
HUE033830T2 (en) 2018-01-29
AU2017204258A1 (en) 2017-07-20
DK3045471T3 (en) 2017-06-26
LTPA2025525I1 (enExample) 2025-07-25
SI4015527T1 (sl) 2025-05-30
JP2015120696A (ja) 2015-07-02
US9546204B2 (en) 2017-01-17
US20240327487A1 (en) 2024-10-03
EP4015527A1 (en) 2022-06-22
MX348622B (es) 2017-06-22
EP2268666A1 (en) 2011-01-05
LTPA2017029I1 (lt) 2017-10-10
BRPI0910461A2 (pt) 2018-03-27
PL3098234T3 (pl) 2025-01-07
AR071479A1 (es) 2010-06-23
AU2017225020A1 (en) 2017-09-28
HK1146284A1 (en) 2011-05-20
EP3098234A1 (en) 2016-11-30
WO2009127826A1 (en) 2009-10-22
PT2268666E (pt) 2014-06-25
JP2024038000A (ja) 2024-03-19
SI2808340T1 (sl) 2016-12-30
FI3098234T3 (fi) 2024-10-31
HRP20170958T1 (hr) 2017-09-22
BRPI0910461B8 (pt) 2021-05-25
LT3045471T (lt) 2017-07-10
PT4015527T (pt) 2025-04-10
HK1199039A1 (en) 2015-06-19
FIC20250025I1 (fi) 2025-07-11
EP2722339A1 (en) 2014-04-23
CN102066414A (zh) 2011-05-18
EP3144318A1 (en) 2017-03-22
EP3098234B1 (en) 2024-07-31
TW200948378A (en) 2009-12-01
SA109300228B1 (ar) 2014-04-08
US20110105398A1 (en) 2011-05-05
NO2017025I1 (no) 2017-06-06
KR20190092608A (ko) 2019-08-07
CN105906702A (zh) 2016-08-31
RU2745557C1 (ru) 2021-03-29
HUE071059T2 (hu) 2025-07-28
ES2610277T3 (es) 2017-04-26
HRP20140535T1 (hr) 2014-07-18
FR17C1020I2 (fr) 2020-04-10
SI3144318T1 (sl) 2020-12-31
EP2808340B1 (en) 2016-08-17
LT3098234T (lt) 2024-09-10
PT2808340T (pt) 2016-11-21
RU2014141994A3 (enExample) 2018-05-28
DK3098234T3 (da) 2024-10-21
FR25C1025I1 (fr) 2025-09-19
AU2014203277A1 (en) 2014-07-24
KR20180095140A (ko) 2018-08-24
CN105906703A (zh) 2016-08-31
AU2017204259A1 (en) 2017-07-20
EP4015527B1 (en) 2025-01-22
US20180079794A1 (en) 2018-03-22
RU2014141994A (ru) 2016-05-10
AU2014203277C1 (en) 2017-07-27
EP3045471B1 (en) 2017-03-29
PL3045471T3 (pl) 2017-10-31
PL2268666T3 (pl) 2014-08-29
CA2725257A1 (en) 2009-10-22
JP2017060476A (ja) 2017-03-30
RU2745557C3 (ru) 2021-12-10
US9771407B2 (en) 2017-09-26
TWI488640B (zh) 2015-06-21
KR20110005863A (ko) 2011-01-19
KR20160056960A (ko) 2016-05-20
US20210332099A1 (en) 2021-10-28
PL3144318T3 (pl) 2021-02-08
DK3144318T3 (da) 2020-12-07
KR101622944B1 (ko) 2016-05-23
BRPI0910461B1 (pt) 2021-02-23
AU2009237479B2 (en) 2014-05-15
HUS1700024I1 (hu) 2017-06-28
HRP20250313T1 (hr) 2025-05-09
AU2009237479A1 (en) 2009-10-22
LT4015527T (lt) 2025-04-10
ES2989729T3 (es) 2024-11-27
EP3045471A1 (en) 2016-07-20
BRPI0910461A8 (pt) 2018-10-16
PT3144318T (pt) 2020-11-04
PT3098234T (pt) 2024-10-21
KR20170110741A (ko) 2017-10-11
EP3144318B1 (en) 2020-09-23
US10995128B2 (en) 2021-05-04
HUE030652T2 (en) 2017-05-29
LTPA2025505I1 (enExample) 2025-02-10
NO2017050I1 (no) 2017-09-28
MX2010011343A (es) 2011-01-20
PL4015527T3 (pl) 2025-05-26
NZ588381A (en) 2012-05-25
JP2022031652A (ja) 2022-02-22
HRP20241187T1 (hr) 2024-12-06
SI2268666T1 (sl) 2014-07-31
MX355457B (es) 2018-04-19
PL2808340T3 (pl) 2017-02-28
HUS2500029I1 (hu) 2025-07-28
HUS2500008I1 (hu) 2025-02-28
JP6486310B2 (ja) 2019-03-20
HUS1700025I1 (hu) 2017-06-28
LTPA2017018I1 (lt) 2017-06-26
ES2629392T3 (es) 2017-08-09
AU2017204258B2 (en) 2017-08-17
FI4015527T3 (fi) 2025-04-29

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