SI1140941T1 - Nitrogen containing heterobicycles as factor xa inhibitors - Google Patents

Nitrogen containing heterobicycles as factor xa inhibitors

Info

Publication number
SI1140941T1
SI1140941T1 SI9930721T SI9930721T SI1140941T1 SI 1140941 T1 SI1140941 T1 SI 1140941T1 SI 9930721 T SI9930721 T SI 9930721T SI 9930721 T SI9930721 T SI 9930721T SI 1140941 T1 SI1140941 T1 SI 1140941T1
Authority
SI
Slovenia
Prior art keywords
inhibitors
factor
nitrogen containing
containing heterobicycles
heterobicycles
Prior art date
Application number
SI9930721T
Other languages
English (en)
Slovenian (sl)
Inventor
John M. Fevig
Joseph Cacciola
Charles G. Clark
Patrick Yuk Sun Lam
Donald J. P. Pinto
James R. Pruitt
Karen A. Rossi
Original Assignee
Bristol-Myers Squibb Pharma Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26811284&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI1140941(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol-Myers Squibb Pharma Company filed Critical Bristol-Myers Squibb Pharma Company
Publication of SI1140941T1 publication Critical patent/SI1140941T1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SI9930721T 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors SI1140941T1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11362898P 1998-12-23 1998-12-23
US12763399P 1999-04-02 1999-04-02
EP99967444A EP1140941B1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors
PCT/US1999/030316 WO2000039131A1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors

Publications (1)

Publication Number Publication Date
SI1140941T1 true SI1140941T1 (en) 2005-04-30

Family

ID=26811284

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9930721T SI1140941T1 (en) 1998-12-23 1999-12-17 Nitrogen containing heterobicycles as factor xa inhibitors

Country Status (26)

Country Link
US (2) US6413980B1 (pt)
EP (1) EP1140941B1 (pt)
JP (1) JP2002533465A (pt)
KR (1) KR100628407B1 (pt)
CN (1) CN100340559C (pt)
AR (1) AR024242A1 (pt)
AT (1) ATE280171T1 (pt)
AU (1) AU759711B2 (pt)
BR (1) BR9917080A (pt)
CA (1) CA2349330C (pt)
DE (1) DE69921358T2 (pt)
DK (1) DK1140941T3 (pt)
EA (1) EA004515B1 (pt)
ES (1) ES2232202T3 (pt)
HK (1) HK1052508B (pt)
HR (1) HRP990396A2 (pt)
IL (2) IL142959A0 (pt)
MX (1) MXPA01006502A (pt)
MY (1) MY138239A (pt)
NO (1) NO319816B1 (pt)
NZ (1) NZ511674A (pt)
PT (1) PT1140941E (pt)
SI (1) SI1140941T1 (pt)
TW (1) TWI225862B (pt)
WO (1) WO2000039131A1 (pt)
ZA (1) ZA200103795B (pt)

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US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US6960595B2 (en) * 2001-03-23 2005-11-01 Bristol-Myers Squibb Pharma Company 5-6 to 5-7 Heterobicycles as factor Xa inhibitors
CA2444571A1 (en) 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1, 4, 5, 6-tetrahydropyrazolo-¬3, 4-c|-pyridin-7-ones as factor xa inhi bitors
WO2002085353A1 (en) * 2001-04-18 2002-10-31 Bristol-Myers Squibb Company 1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-ones as factor xa inhibitors
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CN105085515B (zh) * 2014-05-22 2019-02-01 华北制药股份有限公司 作为凝血因子Xa抑制剂的酰肼类化合物
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CN104311575B (zh) * 2014-09-19 2016-04-20 广东东阳光药业有限公司 含有稠环的吡唑并哌啶酮类化合物及其组合物及用途
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Also Published As

Publication number Publication date
NO20013072L (no) 2001-06-20
US20030004167A1 (en) 2003-01-02
PT1140941E (pt) 2005-02-28
HK1052508B (zh) 2008-08-01
MXPA01006502A (es) 2002-04-08
ATE280171T1 (de) 2004-11-15
AR024242A1 (es) 2002-09-25
JP2002533465A (ja) 2002-10-08
NO20013072D0 (no) 2001-06-20
EP1140941B1 (en) 2004-10-20
EA200100688A1 (ru) 2001-12-24
EA004515B1 (ru) 2004-04-29
HRP990396A2 (en) 2000-08-31
ZA200103795B (en) 2002-08-12
ES2232202T3 (es) 2005-05-16
KR20010092754A (ko) 2001-10-26
AU759711B2 (en) 2003-04-17
US6673810B2 (en) 2004-01-06
CA2349330A1 (en) 2000-07-06
BR9917080A (pt) 2002-03-12
CA2349330C (en) 2009-09-29
NO319816B1 (no) 2005-09-19
US6413980B1 (en) 2002-07-02
EP1140941A1 (en) 2001-10-10
HK1052508A1 (en) 2003-09-19
NZ511674A (en) 2003-11-28
TWI225862B (en) 2005-01-01
MY138239A (en) 2009-05-29
KR100628407B1 (ko) 2006-09-26
CN1391575A (zh) 2003-01-15
IL142959A (en) 2010-05-31
DE69921358T2 (de) 2006-03-09
AU2371700A (en) 2000-07-31
CN100340559C (zh) 2007-10-03
DE69921358D1 (de) 2004-11-25
DK1140941T3 (da) 2005-02-14
WO2000039131A1 (en) 2000-07-06
IL142959A0 (en) 2002-04-21

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