SE7702909L - Sett att framstella nya alkyloximderivat av 7-aminotiazolylacetamidocefalosporansyra - Google Patents

Sett att framstella nya alkyloximderivat av 7-aminotiazolylacetamidocefalosporansyra

Info

Publication number
SE7702909L
SE7702909L SE7702909A SE7702909A SE7702909L SE 7702909 L SE7702909 L SE 7702909L SE 7702909 A SE7702909 A SE 7702909A SE 7702909 A SE7702909 A SE 7702909A SE 7702909 L SE7702909 L SE 7702909L
Authority
SE
Sweden
Prior art keywords
group
carbon atoms
acid
hydrogenolysis
hydrogen
Prior art date
Application number
SE7702909A
Other languages
English (en)
Other versions
SE439485B (sv
Inventor
R Heymes
A Lutz
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of SE7702909L publication Critical patent/SE7702909L/sv
Publication of SE439485B publication Critical patent/SE439485B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7702909A 1976-03-25 1977-03-15 Sett att framstella nya alkyloximderivat av 7-aminotiazolyl-acetamidocefalosporansyra SE439485B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7608690A FR2345153A1 (fr) 1976-03-25 1976-03-25 Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
SE7702909L true SE7702909L (sv) 1977-09-26
SE439485B SE439485B (sv) 1985-06-17

Family

ID=9170952

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7702909A SE439485B (sv) 1976-03-25 1977-03-15 Sett att framstella nya alkyloximderivat av 7-aminotiazolyl-acetamidocefalosporansyra

Country Status (33)

Country Link
US (2) US4476122A (sv)
JP (5) JPS52116492A (sv)
AR (2) AR219916A1 (sv)
AT (1) AT350182B (sv)
AU (1) AU509857B2 (sv)
BE (1) BE852860A (sv)
CA (1) CA1334407C (sv)
CH (2) CH622800A5 (sv)
CS (1) CS209878B2 (sv)
DD (2) DD134526A5 (sv)
DE (3) DE2759885C2 (sv)
DK (1) DK161253C (sv)
ES (2) ES457115A1 (sv)
FR (1) FR2345153A1 (sv)
GB (1) GB1581184A (sv)
GR (1) GR63125B (sv)
HK (1) HK21582A (sv)
HR (1) HRP931392B1 (sv)
HU (1) HU173005B (sv)
IE (1) IE45130B1 (sv)
IL (1) IL51670A (sv)
IT (1) IT1077500B (sv)
LU (1) LU77014A1 (sv)
MX (1) MX5129E (sv)
NL (2) NL7703219A (sv)
NZ (1) NZ183692A (sv)
OA (1) OA05606A (sv)
PL (2) PL124945B1 (sv)
PT (1) PT66353B (sv)
SE (1) SE439485B (sv)
SU (2) SU791246A3 (sv)
YU (2) YU41573B (sv)
ZA (1) ZA771664B (sv)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2345153A1 (fr) 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
FR2367756B1 (fr) * 1976-04-12 1985-07-05 Fujisawa Pharmaceutical Co Derives 2-alcoxyamino-2-(amino-1,3-thiazolyl) acetiques et leur utilisation
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
JPS6011714B2 (ja) 1977-02-17 1985-03-27 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
JPS53101393A (en) 1977-02-17 1978-09-04 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
JPS53103493A (en) 1977-02-18 1978-09-08 Takeda Chem Ind Ltd Cephalosporin derivatives and process for their preparation
PH17188A (en) * 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
DE2714880A1 (de) * 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5498795A (en) * 1978-01-13 1979-08-03 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
FR2387235A1 (fr) * 1978-01-23 1978-11-10 Fujisawa Pharmaceutical Co Procede de preparation de composes d'acide 3,7-disubstitue-3-cephem-4-carboxylique et nouveaux produits ainsi obtenus, ayant une forte activite antibacterienne
FR2421907A1 (fr) * 1978-04-07 1979-11-02 Roussel Uclaf Nouvelles cephalosporines derivees de l'acide 7-/2-(2-amino 4-thiazolyl)2-(carboxymethoxyimino/acetamido 3-substitue cephalosporanique, leur procede de preparation et leur application comme medicaments
MC1259A1 (fr) * 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
US4341775A (en) * 1978-09-11 1982-07-27 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds
DE2945248A1 (de) * 1978-11-13 1980-05-22 Fujisawa Pharmaceutical Co Cephem-verbindungen, verfahren zu ihrer herstellung und sie enthaltende antibakterielle pharmazeutische mittel
JPS5579393A (en) * 1978-12-11 1980-06-14 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
JPS55133385A (en) * 1979-04-03 1980-10-17 Fujisawa Pharmaceut Co Ltd Novel cephem compound, its preparation, and remedy and preventive against microbism
US4331666A (en) * 1979-05-11 1982-05-25 Farmitalia Carlo Erba S.P.A. 3-[(8-Carboxy-6-tetrazolo[1,5-b]pyridazinyl)-thiomethyl]-7-[2-(2-amino-4-thiazolyl)-2-methoxyimino-acetamido]-3-cephem-4-carboxylic acid
IL61458A0 (en) * 1979-12-07 1980-12-31 Erba Farmitalia N-substituted thiazolyl derivatives of oximino-substituted cephalosporins, their preparation and pharmalceutical compositions containing them
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
FR2479229B1 (fr) * 1980-03-26 1986-01-17 Clin Midy Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives
EP0055465B1 (en) * 1980-12-31 1989-08-23 Fujisawa Pharmaceutical Co., Ltd. 7-acylaminocephalosporanic acid derivatives and processes for the preparation thereof
JPS57163386A (en) * 1981-08-13 1982-10-07 Takeda Chem Ind Ltd Cephalosporin derivative and its production
EP0081971A3 (en) * 1981-12-08 1984-09-26 Tanabe Seiyaku Co., Ltd. Novel cephalosporin compound and process for preparing the same
JPS60215690A (ja) * 1984-04-09 1985-10-29 Meiji Seika Kaisha Ltd セフアロスポリン化合物及びそれを有効成分とする抗菌剤
JPS60178891A (ja) * 1984-02-24 1985-09-12 Kureha Chem Ind Co Ltd セファロスポリン誘導体及び該誘導体を含有する医薬
US4874856A (en) * 1985-06-24 1989-10-17 Bristol-Myers Company 3-(substituted)propenyl-7-(aminothiazolylacetamido) ceph-3-em-4-carboxylic acids and esters thereof
US4708955A (en) * 1985-06-24 1987-11-24 Bristol-Myers Company 3-(substituted)propenyl-7-aminothiazol-ylcephalosporanic acids and esters thereof
DE3775798D1 (de) 1986-03-19 1992-02-20 Banyu Pharma Co Ltd Cephalosporinverbindungen, verfahren zu ihrer herstellung und antibakterielle mittel.
GB8819104D0 (en) * 1988-08-11 1988-09-14 Beecham Group Plc Novel compounds
JPH01265093A (ja) * 1988-10-12 1989-10-23 Sankyo Co Ltd 経口用セフアロスポリン化合物
US5261314A (en) * 1988-12-05 1993-11-16 Hirotaka Manufacturing Co., Ltd. Directional control valve for pneumatic cylinder
KR940000112B1 (ko) * 1990-07-05 1994-01-05 주식회사 대웅제약 신규의 3-치환 세펨화합물 및 그의 제조방법
WO2013109205A1 (en) 2012-01-18 2013-07-25 Mahmut Bilgic Pharmaceutical tablet formulations comprising cefetamet
CN108586491B (zh) * 2017-12-26 2021-03-02 山东裕欣药业有限公司 一种盐酸头孢他美酯的制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4024137A (en) * 1971-05-14 1977-05-17 Glaxo Laboratories Limited 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins
GB1399086A (en) * 1971-05-14 1975-06-25 Glaxo Lab Ltd Cephalosporin compounds
GB1453049A (en) * 1973-08-21 1976-10-20 Glaxo Lab Ltd Cephalosporing antibiotics
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
US4298606A (en) * 1974-12-19 1981-11-03 Takeda Chemical Industries, Ltd. Thiazolylacetamido compounds
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
FR2345153A1 (fr) 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Also Published As

Publication number Publication date
PL124945B1 (en) 1983-03-31
AR219916A1 (es) 1980-09-30
SU791246A3 (ru) 1980-12-23
DK161253C (da) 1991-12-09
SE439485B (sv) 1985-06-17
LU77014A1 (sv) 1977-10-03
DK129477A (da) 1977-09-26
JPS58192890A (ja) 1983-11-10
US4476122A (en) 1984-10-09
MX5129E (es) 1983-03-25
DD130788A5 (de) 1978-05-03
BE852860A (fr) 1977-09-26
IE45130L (en) 1977-09-25
AT350182B (de) 1979-05-10
JPS568392A (en) 1981-01-28
CH623590A5 (sv) 1981-06-15
ATA211177A (de) 1978-10-15
AU509857B2 (en) 1980-05-29
AR220333A1 (es) 1980-10-31
US4396618A (en) 1983-08-02
DK161253B (da) 1991-06-17
DE2759885C2 (de) 1985-06-27
FR2345153A1 (fr) 1977-10-21
DE2713272C2 (de) 1983-01-20
IT1077500B (it) 1985-05-04
JPS6229436B2 (sv) 1987-06-25
HRP931392B1 (en) 1996-04-30
YU72577A (en) 1983-10-31
JPS62174084A (ja) 1987-07-30
JPH0257072B2 (sv) 1990-12-03
IL51670A0 (en) 1977-05-31
CS209878B2 (en) 1981-12-31
GB1581184A (en) 1980-12-10
IL51670A (en) 1981-07-31
GR63125B (en) 1979-09-17
PT66353A (fr) 1977-04-01
ZA771664B (en) 1978-04-26
HU173005B (hu) 1979-01-28
AU2360877A (en) 1978-09-28
YU43087B (en) 1989-02-28
NL7703219A (nl) 1977-09-27
OA05606A (fr) 1981-04-30
DE2760156C2 (sv) 1987-08-27
CH622800A5 (sv) 1981-04-30
IE45130B1 (en) 1982-06-30
JPS62174018A (ja) 1987-07-30
ES457115A1 (es) 1978-08-16
JPS638116B2 (sv) 1988-02-19
PL118475B1 (en) 1981-10-31
HK21582A (en) 1982-05-28
YU41573B (en) 1987-10-31
PT66353B (fr) 1979-01-18
DD134526A5 (de) 1979-03-07
FR2345153B1 (sv) 1979-10-05
YU189382A (en) 1983-01-21
SU795482A3 (ru) 1981-01-07
NL8004943A (nl) 1980-11-28
JPH0322849B2 (sv) 1991-03-27
ES469116A1 (es) 1978-11-16
CA1334407C (fr) 1995-02-14
JPS52116492A (en) 1977-09-29
PL196886A1 (pl) 1979-07-16
DE2713272A1 (de) 1977-10-06
NZ183692A (en) 1979-10-25

Similar Documents

Publication Publication Date Title
SE7702909L (sv) Sett att framstella nya alkyloximderivat av 7-aminotiazolylacetamidocefalosporansyra
GEP19970783B (en) Process for the preparation of new oxime derivatives of 7-amino-thiazolyl-acetamido-cephalosporin acid
SE8304239D0 (sv) Nya mellanproidukter anvendbara for framstellning av oximderivat av 3-acetoximetyl-7-aminotiazolyl-acet-amidocefalosporansyra samt forfaranden for framstellning av mellanprodukterna
SE7709801L (sv) Nya cyklopropankarboxylsyror med en polyhalogenerad grupp, sett for framstellning derav samt pesticidkompositioner
IE800599L (en) Derivatives of glycinamide
BE859100A (fr) Procede de preparation de xylose par hydrolyse enzymatique de xylanes.
ES8104321A1 (es) Procedimiento para separar un derivado de alquil-cetohexopi-ranosida
SE7704616L (sv) Sett att framstella nya 11-desoxi-prostaglandin-fÿ2-derivat
SE7613990L (sv) Orasyraderivat sett att framstella nya7-amino-t iazolyl-acetamido-cefalosp
FI830893A0 (fi) Nya fenylpiperazin-derivat samt deras framstaellningsfoerfarande
ES8106511A1 (es) Procedimiento para la preparacion de acidos alcoxi benzofu- ran carboxilicos
ES463682A1 (es) Procedimiento de preparacion de nuevos derivados de la coen-zima b12.
SE7902286L (sv) Sett att framstella nya oximderivat av 3-azido-metyl-7-amino-tiazolyl-acetamido-cefalosporansyra
GB2005246A (en) beta -Lactam compounds and processes for their preparation
US4082776A (en) 6-Alkoxy-4α-hydroxy-2β-tetrahydropyranacetic acid γ-lactones
JPS5692854A (en) Novel imine derived from 33formylcyclopropanee11carboxylic acid ester* its manufacture* its use in corresponding 33vinyl substituted ester manufacture and novel intermediate
ES463121A1 (es) Procedimiento para preparar sales de metal alcalino de aci- dos organicos.
ES460218A1 (es) Procedimiento para preparar derivados de fenetilamina.
ES8102149A1 (es) Un procedimiento de preparacion de nuevos 19-nor-esteroides sustituidos en posicion 2
JPS5332194A (en) Resolution of dl-lysine
ES476024A1 (es) Un procedimiento para preparar derivados de cefalosporina
ES471267A1 (es) Procedimiento para la preparacion de alquilo inferior 2-tri-(inferior) alquilsililacetileno-n-carbetoxiglicinatos y ami-no acidos derivados de ellos
GB1445668A (en) Process for obtaining the optical isomers of penicillamine
SE7711105L (sv) Sett att framstella nya 17-spirosultinderivat och motsvarande gamma-hydroxisyror
ES480329A1 (es) Procedimiento para la preparacion de derivados de acidos benzoilfenoxialcanoicos.

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7702909-8

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7702909-8

Format of ref document f/p: F