ES480329A1 - Procedimiento para la preparacion de derivados de acidos benzoilfenoxialcanoicos. - Google Patents

Procedimiento para la preparacion de derivados de acidos benzoilfenoxialcanoicos.

Info

Publication number
ES480329A1
ES480329A1 ES480329A ES480329A ES480329A1 ES 480329 A1 ES480329 A1 ES 480329A1 ES 480329 A ES480329 A ES 480329A ES 480329 A ES480329 A ES 480329A ES 480329 A1 ES480329 A1 ES 480329A1
Authority
ES
Spain
Prior art keywords
benzoylphenoxyalkanoic
derivatives
acids
activity
normolipemizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES480329A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alfa Farmaceutici SpA
Original Assignee
Alfa Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT03426/78A external-priority patent/IT1106666B/it
Priority claimed from IT363078A external-priority patent/IT1108220B/it
Application filed by Alfa Farmaceutici SpA filed Critical Alfa Farmaceutici SpA
Publication of ES480329A1 publication Critical patent/ES480329A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)

Abstract

Productos que son activos en la reducción del contenido de triglicéridos y colesterol en la sangre y, por consiguiente, son apropiados para utilizarse en la terapia de hiperlipemia y de hipercolesterolemina, que se consideran las causas principales de ciertas enfermedades coronarias y de artereosclerosis.
ES480329A 1978-05-09 1979-05-08 Procedimiento para la preparacion de derivados de acidos benzoilfenoxialcanoicos. Expired ES480329A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT03426/78A IT1106666B (it) 1978-05-09 1978-05-09 Derivati di acidi benzoilfenossi alchili ad azione normolipemizzanti
IT363078A IT1108220B (it) 1978-12-21 1978-12-21 Derivati di acidi benzoilfenossi alcanoici ad azione normolipemizzante

Publications (1)

Publication Number Publication Date
ES480329A1 true ES480329A1 (es) 1980-02-01

Family

ID=26325385

Family Applications (1)

Application Number Title Priority Date Filing Date
ES480329A Expired ES480329A1 (es) 1978-05-09 1979-05-08 Procedimiento para la preparacion de derivados de acidos benzoilfenoxialcanoicos.

Country Status (12)

Country Link
US (3) US4296125A (es)
AT (1) AT367016B (es)
DE (1) DE2918748A1 (es)
DK (1) DK189479A (es)
ES (1) ES480329A1 (es)
FR (1) FR2425425A1 (es)
GB (1) GB2025394B (es)
GR (1) GR72241B (es)
NL (1) NL7903434A (es)
NO (1) NO791532L (es)
SE (1) SE7903982L (es)
YU (1) YU107779A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1130997B (it) * 1980-03-19 1986-06-18 D & D Srl Esteri e derivati chinucleidinici di acidi fenossicarbossilici,procedimento per la loro preparazione e relative composizioni farmaceutiche
WO2008157537A2 (en) * 2007-06-19 2008-12-24 Ironwood Pharmaceuticals, Inc Compositions and methods of use for treating or preventing lipid related disorders
WO2013170858A1 (en) 2012-05-16 2013-11-21 Coloplast A/S Novel polymeric photoinitiators and photoinitiator monomers
CN103703030B (zh) * 2013-09-06 2015-06-10 北京英力科技发展有限公司 一种低迁移性光引发剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (es) * 1967-07-31 1971-03-24
US3907792A (en) * 1969-01-31 1975-09-23 Andre Mieville Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof
DE2003430C3 (de) * 1969-01-31 1978-12-07 Laboratorien Fournier Gmbh, 6600 Saarbruecken p-Benzoylphenoxyisobuttersäureester, ihre Herstellung und diese enthaltende Arzneimittel
US4233298A (en) * 1969-01-31 1980-11-11 Orchimed Sa Esters of p-carbonylphenoxy-isobutyric acids
US3658966A (en) * 1969-09-15 1972-04-25 Kowa Co Methods of treating hypertension
JPS492109B1 (es) * 1969-12-06 1974-01-18
US4055592A (en) * 1972-03-08 1977-10-25 Merck & Co., Inc. N-(Sulfo-lower alkyl) amides of (3-trifluoromethylphenoxy) (4-chlorophenyl)acetic acid
US4035376A (en) * 1972-10-24 1977-07-12 Janssen Pharmaceutica N.V. Aroyl-substituted phenylacetic acid derivatives
JPS5195049A (en) * 1975-02-12 1976-08-20 * **********so*****no***tsu*****************************************ni*no
US4179515A (en) * 1975-02-12 1979-12-18 Orchimed S. A. Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition
US4235896A (en) * 1975-02-12 1980-11-25 Orchimed S.A. Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same
GB1563195A (en) * 1975-08-20 1980-03-19 Sori Soc Rech Ind Derivating of phenoxy-alkylcarboxylic acids
US4250192A (en) * 1977-05-11 1981-02-10 Ciba-Geigy Corporation Novel substituted phenylacetic acid amide compounds
FR2420522A1 (fr) * 1978-03-20 1979-10-19 Unicler Derives de l'acide (m-benzoyl-phenoxy)-2 propionique et leurs applications comme medicaments
US4323691A (en) * 1979-10-09 1982-04-06 Abbott Laboratories Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters
DE2948095A1 (de) * 1979-11-29 1981-06-19 Hoechst Ag, 6230 Frankfurt Phenoxialkan- und phenoxialkencarbonsaeuren und deren derivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
AT367016B (de) 1982-05-25
ATA343279A (de) 1981-10-15
US4515809A (en) 1985-05-07
FR2425425B1 (es) 1983-10-28
YU107779A (en) 1983-04-30
US4378373A (en) 1983-03-29
NO791532L (no) 1979-11-12
DE2918748A1 (de) 1979-11-22
GB2025394B (en) 1982-09-02
DK189479A (da) 1979-11-10
FR2425425A1 (fr) 1979-12-07
GR72241B (es) 1983-10-04
SE7903982L (sv) 1979-11-10
US4296125A (en) 1981-10-20
GB2025394A (en) 1980-01-23
NL7903434A (nl) 1979-11-13

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