AT367016B - Verfahren zur herstellung von neuen benzoylphenoxy-alkansaeurederivaten und von deren salzen mit saeuren bzw. basen - Google Patents

Verfahren zur herstellung von neuen benzoylphenoxy-alkansaeurederivaten und von deren salzen mit saeuren bzw. basen

Info

Publication number
AT367016B
AT367016B AT0343279A AT343279A AT367016B AT 367016 B AT367016 B AT 367016B AT 0343279 A AT0343279 A AT 0343279A AT 343279 A AT343279 A AT 343279A AT 367016 B AT367016 B AT 367016B
Authority
AT
Austria
Prior art keywords
benzoylphenoxy
salts
acids
base
acid derivatives
Prior art date
Application number
AT0343279A
Other languages
English (en)
Other versions
ATA343279A (de
Inventor
Valerio Borzatta
Manlio Cristofori
Mauro Morotti
Giuseppe Mascellani
Original Assignee
Alfa Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT03426/78A external-priority patent/IT1106666B/it
Priority claimed from IT363078A external-priority patent/IT1108220B/it
Application filed by Alfa Farmaceutici Spa filed Critical Alfa Farmaceutici Spa
Priority to AT326181A priority Critical patent/AT370080B/de
Publication of ATA343279A publication Critical patent/ATA343279A/de
Application granted granted Critical
Publication of AT367016B publication Critical patent/AT367016B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/76—Unsaturated compounds containing keto groups
    • C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
AT0343279A 1978-05-09 1979-05-08 Verfahren zur herstellung von neuen benzoylphenoxy-alkansaeurederivaten und von deren salzen mit saeuren bzw. basen AT367016B (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AT326181A AT370080B (de) 1978-12-21 1981-07-23 Verfahren zur herstellung einer neuen benzoylphenoxyalkansaeure, deren aethylester und deren salzen mit basen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT03426/78A IT1106666B (it) 1978-05-09 1978-05-09 Derivati di acidi benzoilfenossi alchili ad azione normolipemizzanti
IT363078A IT1108220B (it) 1978-12-21 1978-12-21 Derivati di acidi benzoilfenossi alcanoici ad azione normolipemizzante

Publications (2)

Publication Number Publication Date
ATA343279A ATA343279A (de) 1981-10-15
AT367016B true AT367016B (de) 1982-05-25

Family

ID=26325385

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0343279A AT367016B (de) 1978-05-09 1979-05-08 Verfahren zur herstellung von neuen benzoylphenoxy-alkansaeurederivaten und von deren salzen mit saeuren bzw. basen

Country Status (12)

Country Link
US (3) US4296125A (de)
AT (1) AT367016B (de)
DE (1) DE2918748A1 (de)
DK (1) DK189479A (de)
ES (1) ES480329A1 (de)
FR (1) FR2425425A1 (de)
GB (1) GB2025394B (de)
GR (1) GR72241B (de)
NL (1) NL7903434A (de)
NO (1) NO791532L (de)
SE (1) SE7903982L (de)
YU (1) YU107779A (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1130997B (it) * 1980-03-19 1986-06-18 D & D Srl Esteri e derivati chinucleidinici di acidi fenossicarbossilici,procedimento per la loro preparazione e relative composizioni farmaceutiche
US20090054450A1 (en) * 2007-06-19 2009-02-26 Ironwood Pharmaceuticals, Inc. Compositions and methods of use for treating or preventing lipid related disorders
US9296835B2 (en) 2012-05-16 2016-03-29 Coloplast A/S Polymeric photoinitiators and photoinitiator monomers
CN103703030B (zh) * 2013-09-06 2015-06-10 北京英力科技发展有限公司 一种低迁移性光引发剂
WO2020146876A2 (en) * 2019-01-11 2020-07-16 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Anti-cancer compositions and methods of use

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (de) * 1967-07-31 1971-03-24
US3907792A (en) * 1969-01-31 1975-09-23 Andre Mieville Phenoxy-alkyl-carboxylic acid derivatives and the preparation thereof
US4233298A (en) * 1969-01-31 1980-11-11 Orchimed Sa Esters of p-carbonylphenoxy-isobutyric acids
DE2003430C3 (de) * 1969-01-31 1978-12-07 Laboratorien Fournier Gmbh, 6600 Saarbruecken p-Benzoylphenoxyisobuttersäureester, ihre Herstellung und diese enthaltende Arzneimittel
US3658966A (en) * 1969-09-15 1972-04-25 Kowa Co Methods of treating hypertension
JPS492109B1 (de) * 1969-12-06 1974-01-18
US4055592A (en) * 1972-03-08 1977-10-25 Merck & Co., Inc. N-(Sulfo-lower alkyl) amides of (3-trifluoromethylphenoxy) (4-chlorophenyl)acetic acid
US4035376A (en) * 1972-10-24 1977-07-12 Janssen Pharmaceutica N.V. Aroyl-substituted phenylacetic acid derivatives
US4235896A (en) * 1975-02-12 1980-11-25 Orchimed S.A. Benzyl-phenoxy acid esters and hyperlipaemia compositions containing the same
US4179515A (en) * 1975-02-12 1979-12-18 Orchimed S. A. Benzoylphenoxy propionic acid, esters thereof and pharmaceutical composition
JPS5195049A (en) * 1975-02-12 1976-08-20 * **********so*****no***tsu*****************************************ni*no
GB1563195A (en) * 1975-08-20 1980-03-19 Sori Soc Rech Ind Derivating of phenoxy-alkylcarboxylic acids
US4250192A (en) * 1977-05-11 1981-02-10 Ciba-Geigy Corporation Novel substituted phenylacetic acid amide compounds
FR2420522A1 (fr) * 1978-03-20 1979-10-19 Unicler Derives de l'acide (m-benzoyl-phenoxy)-2 propionique et leurs applications comme medicaments
US4323691A (en) * 1979-10-09 1982-04-06 Abbott Laboratories Hydroxyaminomethyl derivatives of benzoyl di-substituted α-phenoxyalkanoyl esters
DE2948095A1 (de) * 1979-11-29 1981-06-19 Hoechst Ag, 6230 Frankfurt Phenoxialkan- und phenoxialkencarbonsaeuren und deren derivate, ihre herstellung und verwendung

Also Published As

Publication number Publication date
NL7903434A (nl) 1979-11-13
ATA343279A (de) 1981-10-15
FR2425425A1 (fr) 1979-12-07
ES480329A1 (es) 1980-02-01
NO791532L (no) 1979-11-12
GB2025394B (en) 1982-09-02
YU107779A (en) 1983-04-30
US4296125A (en) 1981-10-20
GR72241B (de) 1983-10-04
GB2025394A (en) 1980-01-23
US4515809A (en) 1985-05-07
DE2918748A1 (de) 1979-11-22
FR2425425B1 (de) 1983-10-28
DK189479A (da) 1979-11-10
US4378373A (en) 1983-03-29
SE7903982L (sv) 1979-11-10

Similar Documents

Publication Publication Date Title
AT374191B (de) Verfahren zur herstellung von neuen substituierten acethydroxamsaeuren und deren salzen
AT363465B (de) Verfahren zur herstellung von neuen 5-aroyl-1,2 -dihydro-3h-pyrrolo-(1,2-a)-pyrrol-1-carbonsaeureestern und -salzen
AT373887B (de) Verfahren zur herstellung von neuen n-heterocyclyl-4-piperidinaminen und deren saeureadditionssalzen
AT344683B (de) Verfahren zur herstellung von neuen substituierten 3-phenoxy-2-hydroxy-1-aminopropanen und deren saeureadditionssalzen
AT340895B (de) Verfahren zur herstellung von neuen p-trifluormethylacylophenon-o- (2-aminoathyl) -oximathern und deren saureadditionssalzen
AT363464B (de) Verfahren zur herstellung von neuen in stellung 5 substituierten 1,2-dihydro-3h-pyrrolo-(1,2-a) -pyrrol-1-carbonsaeureestern und -salzen
AT366662B (de) Verfahren zur herstellung von neuen 1-aryloxy-3- nitratoalkylamino-2-propanolen und deren saeureadditionssalzen
AT364358B (de) Verfahren zur herstellung von neuen 1(benzazolylalkyl)-piperidinen und deren salzen mit saeuren
AT347463B (de) Verfahren zur herstellung von neuen 1,1,1- triarylalkylaminen und deren saeureadditions- salzen
AT360535B (de) Verfahren zur herstellung von neuen 1-azaxan- thon-3-carbonsaeuren und deren salzen
AT369731B (de) Verfahren zur herstellung von neuen 4-pyridon-3-carbonsaeurederivaten und deren salzen
AT350552B (de) Verfahren zur herstellung von neuen propargyl- 2-phenylamino-imidazolinen-(2) und deren saeureadditionssalzen
AT361481B (de) Verfahren zur herstellung von neuen 3-alkyl- -isochinolyl-5-iminothiazol(3,4-b)isochinolin- -derivaten und von deren saeureadditionssalzen
AT367016B (de) Verfahren zur herstellung von neuen benzoylphenoxy-alkansaeurederivaten und von deren salzen mit saeuren bzw. basen
AT360530B (de) Verfahren zur herstellung von neuen 3,5- disubstituierten-1h-1,2,4-triazolen und von deren salzen mit pharmazeutisch verwendbaren saeuren
AT340896B (de) Verfahren zur herstellung von neuen p-halogen-acylophenon- o - (2-aminoathyl)-oximathern und deren saureadditionssalzen
ATA328376A (de) Verfahren zur herstellung von neuen 3-aminomethyl-2-phenylbicyclo(2,2,2)octanen und deren saureadditionssalzen
AT372081B (de) Verfahren zur herstellung von neuen substituierten n-iminomethylpiperidinen und von deren saeureadditionssalzen
AT363463B (de) Verfahren zur herstellung von neuen 5-sulfamoyl-orthanilsaeuren und deren physiologisch vertraeglichen salzen
AT351509B (de) Verfahren zur herstellung von neuen 3-phenoxy-2 -hydroxy-1-phenoxy- oder -1-phenylthioalkyl- amino-propanen und von deren saeureadditions- salzen
AT340897B (de) Verfahren zur herstellung von neuen p-methylthioacylophenon-o- (2-aminoathyl)-oximathern und deren saureadditionssalzen
AT360010B (de) Verfahren zur herstellung von neuen azabicyclo- alkanen und deren physiologisch vertraeglichen saeureadditionssalzen
ATA326181A (de) Verfahren zur herstellung von neuen benzoyl alkansaeure, derne aethylester und deren salzen mit basen
AT349024B (de) Verfahren zur herstellung von neuen naphthyridinderivaten und von deren saeureadditionssalzen
AT340894B (de) Verfahren zur herstellung von neuen p-nitro-acylophenon-o- (2-aminoathyl) -oximather und deren saureadditionssalzen

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee
ELJ Ceased due to non-payment of the annual fee