ES469999A1 - Procedimiento de preparar nuevos derivados de 5,6-dihidroi- midazo(5,1-a)isoquinolina - Google Patents
Procedimiento de preparar nuevos derivados de 5,6-dihidroi- midazo(5,1-a)isoquinolinaInfo
- Publication number
- ES469999A1 ES469999A1 ES469999A ES469999A ES469999A1 ES 469999 A1 ES469999 A1 ES 469999A1 ES 469999 A ES469999 A ES 469999A ES 469999 A ES469999 A ES 469999A ES 469999 A1 ES469999 A1 ES 469999A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- denotes
- oxygen
- optionally substituted
- isoquinoline derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000002183 isoquinolinyl group Chemical class C1(=NC=CC2=CC=CC=C12)* 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 239000001301 oxygen Substances 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- WBZLGNODHLEZLU-UHFFFAOYSA-N 5,6-dihydroimidazo[5,1-a]isoquinoline Chemical class C12=CC=CC=C2CCN2C1=CN=C2 WBZLGNODHLEZLU-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000005036 alkoxyphenyl group Chemical group 0.000 abstract 1
- -1 aminophenyl Chemical group 0.000 abstract 1
- 230000003182 bronchodilatating effect Effects 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000002541 furyl group Chemical group 0.000 abstract 1
- 125000005059 halophenyl group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000004464 hydroxyphenyl group Chemical group 0.000 abstract 1
- 125000005245 nitryl group Chemical group [N+](=O)([O-])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/04—Flat or tray type, drawers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/26—Conditioning fluids entering or exiting the reaction vessel
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/44—Polycarboxylic acids
- C12P7/48—Tricarboxylic acids, e.g. citric acid
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/80—Elimination or reduction of contamination by undersired ferments, e.g. aseptic cultivation
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Sustainable Development (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Procedimiento de preparar nuevos derivados de 5,6-dihidroimidazo (5,1-a) isoquinolina, de la fórmula general (I) **(Fórmula)** en la cual R representa hidrógeno o alquilo C1-4, A significa nitrilo o carbamoílo, B es un solo par de electrones u oxígeno, e Y es hidrógeno, alquilo C1-5'', fenilo, hidroxifenilo, aminofenilo, furilo (en su caso, substituido), alcoxifenilo, halogenofenilo, alquilo (en su caso substituido por fenilo, conteniendo 2-4 átomos de carbono) o, si B no es oxígeno, Y significa hidroxi, y sus sales formadas con ácidos o bases.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU77CI1739A HU176214B (en) | 1977-05-18 | 1977-05-18 | Process for producing new 5,6-dihydro-imidazo-square bracket-5,1-a-square bracket closed-isoquinolin derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES469999A1 true ES469999A1 (es) | 1979-09-16 |
Family
ID=10994651
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469999A Expired ES469999A1 (es) | 1977-05-18 | 1978-05-18 | Procedimiento de preparar nuevos derivados de 5,6-dihidroi- midazo(5,1-a)isoquinolina |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS53147094A (es) |
| AT (1) | AT363476B (es) |
| CH (1) | CH638206A5 (es) |
| DD (1) | DD136138A5 (es) |
| DE (1) | DE2821226A1 (es) |
| ES (1) | ES469999A1 (es) |
| FR (1) | FR2391213A1 (es) |
| GB (1) | GB1594907A (es) |
| HU (1) | HU176214B (es) |
| PL (1) | PL117925B1 (es) |
| SU (1) | SU852173A3 (es) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0198227A3 (de) * | 1985-03-20 | 1988-01-13 | Boehringer Ingelheim Kg | Imidazo-Isochinoline und Imidazo-Thienopyridin-Verbindungen, Arzneimittel enthaltend diese Verbindungen und Verfahren zu ihrer Herstellung |
| DE102005019181A1 (de) * | 2005-04-25 | 2006-10-26 | Novartis Ag | Peptid-Deformylase (PDF) Inhibitoren 1 |
| CN101166740B (zh) * | 2005-04-25 | 2010-12-29 | 诺瓦提斯公司 | 用作肽脱甲酰基酶(pdf)抑制剂的咪唑并[1,2-a]吡啶衍生物 |
| TW200845988A (en) * | 2007-04-05 | 2008-12-01 | Astrazeneca Ab | New compounds and their uses 707 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU167240B (es) * | 1972-06-30 | 1975-09-27 |
-
1977
- 1977-05-18 HU HU77CI1739A patent/HU176214B/hu unknown
-
1978
- 1978-05-16 DE DE19782821226 patent/DE2821226A1/de not_active Withdrawn
- 1978-05-17 GB GB20204/78A patent/GB1594907A/en not_active Expired
- 1978-05-17 SU SU782617907A patent/SU852173A3/ru active
- 1978-05-17 CH CH535878A patent/CH638206A5/de not_active IP Right Cessation
- 1978-05-18 ES ES469999A patent/ES469999A1/es not_active Expired
- 1978-05-18 FR FR7814743A patent/FR2391213A1/fr active Granted
- 1978-05-18 DD DD78205458A patent/DD136138A5/xx unknown
- 1978-05-18 AT AT0359778A patent/AT363476B/de not_active IP Right Cessation
- 1978-05-18 PL PL1978206901A patent/PL117925B1/pl unknown
- 1978-05-18 JP JP5836378A patent/JPS53147094A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| PL117925B1 (en) | 1981-09-30 |
| DD136138A5 (de) | 1979-06-20 |
| DE2821226A1 (de) | 1978-11-30 |
| CH638206A5 (en) | 1983-09-15 |
| ATA359778A (de) | 1981-01-15 |
| JPS53147094A (en) | 1978-12-21 |
| GB1594907A (en) | 1981-08-05 |
| PL206901A1 (pl) | 1979-09-10 |
| AT363476B (de) | 1981-08-10 |
| FR2391213B1 (es) | 1981-09-04 |
| HU176214B (en) | 1981-01-28 |
| SU852173A3 (ru) | 1981-07-30 |
| FR2391213A1 (fr) | 1978-12-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19980401 |