ES476024A1 - Un procedimiento para preparar derivados de cefalosporina - Google Patents

Un procedimiento para preparar derivados de cefalosporina

Info

Publication number
ES476024A1
ES476024A1 ES476024A ES476024A ES476024A1 ES 476024 A1 ES476024 A1 ES 476024A1 ES 476024 A ES476024 A ES 476024A ES 476024 A ES476024 A ES 476024A ES 476024 A1 ES476024 A1 ES 476024A1
Authority
ES
Spain
Prior art keywords
cephem
methyl
carboxylic acids
methoxymethyl esters
substituted imidazolidinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476024A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES476024A1 publication Critical patent/ES476024A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/58—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with a nitrogen atom, which is a member of a hetero ring, attached in position 7
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. Un procedimiento para preparar derivados de cefalosporina de fórmula: **Fórmula-01** cuyo procedimiento comprende hacer reaccionar en cualquier orden un compuesto de fórmula: **Fórmula-02** con: a) acetona, y b) bromometil-metil-éter.
ES476024A 1977-12-16 1978-12-14 Un procedimiento para preparar derivados de cefalosporina Expired ES476024A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/861,334 US4125716A (en) 1977-12-16 1977-12-16 Methoxymethyl esters of substituted imidazolidinyl-3-methyl-3-cephem-4-carboxylic acids

Publications (1)

Publication Number Publication Date
ES476024A1 true ES476024A1 (es) 1980-05-16

Family

ID=25335521

Family Applications (1)

Application Number Title Priority Date Filing Date
ES476024A Expired ES476024A1 (es) 1977-12-16 1978-12-14 Un procedimiento para preparar derivados de cefalosporina

Country Status (13)

Country Link
US (1) US4125716A (es)
JP (1) JPS5490193A (es)
BE (1) BE872744A (es)
CA (1) CA1100946A (es)
CH (1) CH637968A5 (es)
DE (1) DE2854041A1 (es)
ES (1) ES476024A1 (es)
FR (1) FR2411840A1 (es)
GB (1) GB2010269B (es)
GR (1) GR70245B (es)
IT (1) IT1109343B (es)
NL (1) NL7812236A (es)
YU (1) YU42169B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54112892A (en) * 1978-02-23 1979-09-04 Shionogi & Co Ltd Substituted imidazolidinyl-3-chloro-3-cephem-4-carboxylic acid
US4217275A (en) * 1979-02-28 1980-08-12 Bristol-Myers Company β-Lactam antibiotic esterification process using methoxymethyl methane sulfonate
US4219495A (en) * 1979-02-28 1980-08-26 Bristol-Myers Company Methoxymethyl p-toluenesulfonate
US20050181353A1 (en) * 2004-02-17 2005-08-18 Rao Galla C. Stabilization of cells and biological specimens for analysis

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3489750A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
USRE29164E (en) 1967-09-05 1977-03-29 Bristol-Myers Company 7-Amino-cephalosporanic and decephalosporanic acid derivatives
US3714146A (en) * 1970-10-05 1973-01-30 Bristol Myers Co Novel syntheses of cephalexin and intermediates therefor
JPS5513719B2 (es) * 1972-12-06 1980-04-10
US3996236A (en) * 1973-03-24 1976-12-07 Bristol-Myers Company Methoxymethyl D-6-(2,2-dimethyl-5-oxo-4-phenyl-1-imidazolidinyl)penicillanate

Also Published As

Publication number Publication date
FR2411840A1 (fr) 1979-07-13
NL7812236A (nl) 1979-06-19
GB2010269A (en) 1979-06-27
JPS5490193A (en) 1979-07-17
YU42169B (en) 1988-06-30
YU292478A (en) 1983-01-21
IT7852314A0 (it) 1978-12-15
FR2411840B1 (es) 1983-04-01
DE2854041A1 (de) 1979-06-28
IT1109343B (it) 1985-12-16
CA1100946A (en) 1981-05-12
GR70245B (es) 1982-09-01
CH637968A5 (de) 1983-08-31
US4125716A (en) 1978-11-14
GB2010269B (en) 1982-06-16
BE872744A (fr) 1979-06-13

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202