SE460198B - Foerfarande foer framstaellning av 5'-deoxi-5'-metyltioadenosin - Google Patents

Foerfarande foer framstaellning av 5'-deoxi-5'-metyltioadenosin

Info

Publication number
SE460198B
SE460198B SE8102489A SE8102489A SE460198B SE 460198 B SE460198 B SE 460198B SE 8102489 A SE8102489 A SE 8102489A SE 8102489 A SE8102489 A SE 8102489A SE 460198 B SE460198 B SE 460198B
Authority
SE
Sweden
Prior art keywords
mta
aggregation
formula
same
induced
Prior art date
Application number
SE8102489A
Other languages
English (en)
Swedish (sv)
Other versions
SE8102489L (sv
Inventor
G Stramentinoli
F Gennari
Original Assignee
Bioresearch Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Srl filed Critical Bioresearch Srl
Publication of SE8102489L publication Critical patent/SE8102489L/xx
Publication of SE460198B publication Critical patent/SE460198B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE8102489A 1980-04-22 1981-04-21 Foerfarande foer framstaellning av 5'-deoxi-5'-metyltioadenosin SE460198B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (it) 1980-04-22 1980-04-22 Derivati adenosinici ad attivita' antinfiammatoria ed analgesica e composizioni terapeutiche che li contengono come principio attivo

Publications (2)

Publication Number Publication Date
SE8102489L SE8102489L (sv) 1981-10-23
SE460198B true SE460198B (sv) 1989-09-18

Family

ID=11183457

Family Applications (3)

Application Number Title Priority Date Filing Date
SE8102489A SE460198B (sv) 1980-04-22 1981-04-21 Foerfarande foer framstaellning av 5'-deoxi-5'-metyltioadenosin
SE8700913A SE466238B (sv) 1980-04-22 1987-03-04 Terapeutisk komposition innehaallande adenosinderivat
SE8700914A SE464635B (sv) 1980-04-22 1987-03-04 Anvaendning av ett adenosinderivat foer framstaellning av ett laekemedel foer behandling av inflammation, smaerta och feber

Family Applications After (2)

Application Number Title Priority Date Filing Date
SE8700913A SE466238B (sv) 1980-04-22 1987-03-04 Terapeutisk komposition innehaallande adenosinderivat
SE8700914A SE464635B (sv) 1980-04-22 1987-03-04 Anvaendning av ett adenosinderivat foer framstaellning av ett laekemedel foer behandling av inflammation, smaerta och feber

Country Status (17)

Country Link
JP (2) JPS56166117A (ja)
AR (1) AR231144A1 (ja)
BE (1) BE888472A (ja)
CA (1) CA1198105A (ja)
CH (2) CH650514A5 (ja)
DE (1) DE3116067A1 (ja)
DK (1) DK159453C (ja)
ES (2) ES501539A0 (ja)
FI (1) FI70227C (ja)
FR (1) FR2491761A1 (ja)
GB (3) GB2074446B (ja)
IT (1) IT1193529B (ja)
LU (1) LU83307A1 (ja)
MX (1) MX9203630A (ja)
NL (1) NL192111C (ja)
NO (1) NO150515C (ja)
SE (3) SE460198B (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (it) * 1984-12-06 1987-08-26 Bioresearch Spa Sali della 5'-metiltio-5'-deossiadenosina con acidi solfonici a lunga catena alchilica
IT1227049B (it) * 1988-07-29 1991-03-14 Bioresearch Spa Impiego di derivati adenosinici per la preparazione di composizioni farmaceutiche aventi attivita' immunostimolante.
JPH0497287A (ja) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd 画像表示集積回路
PT1891961E (pt) * 2005-03-17 2009-12-17 Proyecto Biomedicina Cima Sl Uso de 5'-metiltioadenosina (mta) na prevenção e/ou no tratamento de doenças auto-imunes e/ou rejeição de transplante
ES2259552B1 (es) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. Empleo de 5'-metiltioadenosina (mta) en la prevencion y/o tratamiento de enfermedades autoinmunes y/o rechazo de transplantes.
DE102010027595A1 (de) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Vermeidung von Ischämie- oder Degenerations-Schäden im Gehirn bei Anwendung von Adenosin-Derivaten
DE102011005232A1 (de) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosin und seine Derivate zur Verwendung in der Schmerztherapie
KR102245628B1 (ko) * 2013-04-05 2021-04-28 라이온 가부시키가이샤 내복 조성물
CN105102609B (zh) * 2013-04-05 2018-07-20 狮王株式会社 酵母培养物和内服组合物
JP6226962B2 (ja) * 2013-04-05 2017-11-08 ライオン株式会社 ノンレム睡眠促進剤、深睡眠促進剤、自然睡眠誘発剤、および睡眠初期デルタパワー向上剤

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (de) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Verfahren zur Herstellung neuer 5'-Sulfoxyde von Nucleosiden
DE1545645A1 (de) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Verfahren zur Herstellung von disubstituierten Adenosin-Derivaten
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast
FR2313937A1 (fr) * 1975-06-09 1977-01-07 Anvar Medicament a base de 5' thioethers de l'adenosine
FR2424027A1 (fr) * 1978-04-28 1979-11-23 Merieux Inst Nouveau medicament, notamment sedatif et inducteur de sommeil et compositions pharmaceutiques la renfermant

Also Published As

Publication number Publication date
DE3116067A1 (de) 1982-03-11
FR2491761A1 (fr) 1982-04-16
NO150515B (no) 1984-07-23
GB2144409A (en) 1985-03-06
SE8700913D0 (sv) 1987-03-04
FR2491761B1 (ja) 1984-01-06
JPS56166117A (en) 1981-12-21
GB2144038B (en) 1985-08-29
ES511039A0 (es) 1983-06-01
ES8306378A1 (es) 1983-06-01
IT8021550A0 (it) 1980-04-22
GB8413454D0 (en) 1984-07-04
DE3116067C2 (ja) 1992-12-17
DK159453C (da) 1991-03-18
FI70227C (fi) 1986-09-15
IT1193529B (it) 1988-07-08
SE8102489L (sv) 1981-10-23
CA1198105A (en) 1985-12-17
NL192111C (nl) 1997-02-04
CH650514A5 (de) 1985-07-31
GB2144038A (en) 1985-02-27
BE888472A (fr) 1981-08-17
FI811249L (fi) 1981-10-23
SE8700914L (sv) 1987-03-04
MX9203630A (es) 1992-09-01
SE8700914D0 (sv) 1987-03-04
NO150515C (no) 1984-10-31
LU83307A1 (fr) 1981-07-24
GB2144409B (en) 1985-09-11
ES8206551A1 (es) 1982-08-16
GB2074446A (en) 1981-11-04
JPH0246599B2 (ja) 1990-10-16
GB8321947D0 (en) 1983-09-14
NL192111B (nl) 1996-10-01
GB2074446B (en) 1985-04-11
SE8700913L (sv) 1987-03-04
AR231144A1 (es) 1984-09-28
NL8101984A (nl) 1981-11-16
FI70227B (fi) 1986-02-28
JPH0249288B2 (ja) 1990-10-29
DK159453B (da) 1990-10-15
NO811346L (no) 1981-10-23
ES501539A0 (es) 1982-08-16
SE464635B (sv) 1991-05-27
SE466238B (sv) 1992-01-20
DK176481A (da) 1981-10-23
JPH01301692A (ja) 1989-12-05
CH645544A5 (de) 1984-10-15

Similar Documents

Publication Publication Date Title
US4579849A (en) N-alkylguanine acyclonucleosides as antiviral agents
EP0025692B1 (en) Quinone derivatives, their production and use
USRE37077E1 (en) Adenosine derivatives and pharmaceutical composition thereof
KR930002492B1 (ko) 6-티오크산틴 유도체의 제조방법
SK95193A3 (en) Antiviral nucleoside combination
JPS63239294A (ja) 新規アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
PT98035A (pt) Processo para a preparacao de novos benzimidazois substituidos e de composicoes farmaceuticas que os contem
SE460198B (sv) Foerfarande foer framstaellning av 5'-deoxi-5'-metyltioadenosin
US4454122A (en) Adenosine derivatives of anti-inflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle
FI77666B (fi) Foerfarande foer framstaellning av farmaceutiskt anvaendbara n6-substituerade adenosiner.
US4373097A (en) Process for preparing adenosine derivatives of anti-inflammatory and analgesic activity
HU187476B (en) Process for preparing xanthata derivatives
EP0129984B1 (en) Novel 2'-deoxy-5-substituted uridine derivatives, processes for preparing the same and antitumor agent containing the same
US5574149A (en) Method of treating HIV infections with 2',3'-dideoxy-3'-fluoro-5-chlorouridine
US5157114A (en) 2',3'-dideoxy-3'-fluoro-5-ethyngluridine
EP0184248A2 (en) Salts of 5'-methylthio-5'-deoxyadenosine with long-alkyl chain sulphonic acids
FOX et al. Nucleosides. VIII. Synthesis of 5-Nitrocytidine and Related Nucleosides1
JPS6322541A (ja) 炎症性気管支肺疾患を治療するサルサレ−トとグアヤコ−ルのエステル類
JPH0267295A (ja) プリン誘導体
US3855206A (en) Adenosine-5{40 -carbohydroxamic esters
JPS6223747B2 (ja)
HU179949B (en) Process for preparing nitroso-carbamide derivatives
CA1209915A (en) Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle
US4342753A (en) Carboxyalkyl derivatives of rutin poly(H-)sulfate
US5198539A (en) 5'-esters of 2',3'-dideoxy-3'-fluoro-5-ethynyluridine

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8102489-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8102489-5

Format of ref document f/p: F