GB8321947D0 - Preparation of 5'-deoxy-5'-methyl-thioadenosine - Google Patents

Preparation of 5'-deoxy-5'-methyl-thioadenosine

Info

Publication number
GB8321947D0
GB8321947D0 GB838321947A GB8321947A GB8321947D0 GB 8321947 D0 GB8321947 D0 GB 8321947D0 GB 838321947 A GB838321947 A GB 838321947A GB 8321947 A GB8321947 A GB 8321947A GB 8321947 D0 GB8321947 D0 GB 8321947D0
Authority
GB
United Kingdom
Prior art keywords
thioadenosine
deoxy
methyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB838321947A
Other versions
GB2144409B (en
GB2144409A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Publication of GB8321947D0 publication Critical patent/GB8321947D0/en
Publication of GB2144409A publication Critical patent/GB2144409A/en
Application granted granted Critical
Publication of GB2144409B publication Critical patent/GB2144409B/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
GB08321947A 1980-04-22 1983-08-15 Preparation of 5'-deoxy-5'-methylthioadenosine Expired GB2144409B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (en) 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE

Publications (3)

Publication Number Publication Date
GB8321947D0 true GB8321947D0 (en) 1983-09-14
GB2144409A GB2144409A (en) 1985-03-06
GB2144409B GB2144409B (en) 1985-09-11

Family

ID=11183457

Family Applications (3)

Application Number Title Priority Date Filing Date
GB8112428A Expired GB2074446B (en) 1980-04-22 1981-04-22 Adenosine derivatives of antiinflammatory and analgesic activity and therapeutic compositions containing them
GB08321947A Expired GB2144409B (en) 1980-04-22 1983-08-15 Preparation of 5'-deoxy-5'-methylthioadenosine
GB08413454A Expired GB2144038B (en) 1980-04-22 1984-05-25 Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB8112428A Expired GB2074446B (en) 1980-04-22 1981-04-22 Adenosine derivatives of antiinflammatory and analgesic activity and therapeutic compositions containing them

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB08413454A Expired GB2144038B (en) 1980-04-22 1984-05-25 Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them

Country Status (17)

Country Link
JP (2) JPS56166117A (en)
AR (1) AR231144A1 (en)
BE (1) BE888472A (en)
CA (1) CA1198105A (en)
CH (2) CH645544A5 (en)
DE (1) DE3116067A1 (en)
DK (1) DK159453C (en)
ES (2) ES501539A0 (en)
FI (1) FI70227C (en)
FR (1) FR2491761A1 (en)
GB (3) GB2074446B (en)
IT (1) IT1193529B (en)
LU (1) LU83307A1 (en)
MX (1) MX9203630A (en)
NL (1) NL192111C (en)
NO (1) NO150515C (en)
SE (3) SE460198B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (en) * 1984-12-06 1987-08-26 Bioresearch Spa SALTS OF 5'-METHYLLIUM-5'-DEOXYDENOSINE WITH LONG ALCHYLIC CHAIN SULPHONIC ACIDS
IT1227049B (en) * 1988-07-29 1991-03-14 Bioresearch Spa USE OF ADENOSINIC DERIVATIVES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS HAVING IMMUNOSTIMULATING ACTIVITIES.
JPH0497287A (en) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd Picture display integrated circuit
ES2259552B1 (en) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. EMPLOYMENT OF 5'-METHYLTIOENENINE (MTA) IN THE PREVENTION AND / OR TREATMENT OF AUTOIMMUNE DISEASES AND / OR REPLACEMENT OF TRANSPLANTS.
WO2006097547A1 (en) * 2005-03-17 2006-09-21 Proyecto De Biomedicina Cima S.L. Use of 5'-methylthioadenosine (mta) in the prevention and/or treatment of autoimmune diseases and/or transplant rejection
DE102010027595A1 (en) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Clinical application of adenosine derivative, preferably (dihydroxyphenyl)ethyl-amino-purin-9-yl-(hydroxymethyl)oxolane-diol, for reducing body temperature during impending ischemia of brain vessels, which occur during heart attacks
DE102011005232A1 (en) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosine and its derivatives for use in pain therapy
KR20150139508A (en) * 2013-04-05 2015-12-11 라이온 가부시키가이샤 Yeast culture, and composition for internal application
WO2014163150A1 (en) * 2013-04-05 2014-10-09 ライオン株式会社 Composition for internal use
WO2014163152A1 (en) * 2013-04-05 2014-10-09 ライオン株式会社 Non-rem sleep-promoting agent, deep sleep-promoting agent and natural sleep-inducing agent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (en) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Process for the preparation of new 5'-sulfoxides of nucleosides
DE1545645A1 (en) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Process for the preparation of disubstituted adenosine derivatives
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast
FR2313937A1 (en) * 1975-06-09 1977-01-07 Anvar DRUG BASED ON 5 'THIOETHERS OF ADENOSINE
FR2424027A1 (en) * 1978-04-28 1979-11-23 Merieux Inst NEW MEDICINAL PRODUCT, IN PARTICULAR SEDATIVE AND SLEEP INDUCER AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Also Published As

Publication number Publication date
ES8206551A1 (en) 1982-08-16
DE3116067C2 (en) 1992-12-17
DK159453C (en) 1991-03-18
IT1193529B (en) 1988-07-08
SE8102489L (en) 1981-10-23
JPS56166117A (en) 1981-12-21
IT8021550A0 (en) 1980-04-22
SE8700913D0 (en) 1987-03-04
GB8413454D0 (en) 1984-07-04
FI811249L (en) 1981-10-23
DE3116067A1 (en) 1982-03-11
JPH0246599B2 (en) 1990-10-16
MX9203630A (en) 1992-09-01
GB2144038A (en) 1985-02-27
NO150515B (en) 1984-07-23
ES511039A0 (en) 1983-06-01
FI70227C (en) 1986-09-15
FI70227B (en) 1986-02-28
AR231144A1 (en) 1984-09-28
NL8101984A (en) 1981-11-16
SE8700914L (en) 1987-03-04
GB2074446A (en) 1981-11-04
SE466238B (en) 1992-01-20
ES501539A0 (en) 1982-08-16
SE464635B (en) 1991-05-27
CH645544A5 (en) 1984-10-15
CA1198105A (en) 1985-12-17
NO150515C (en) 1984-10-31
JPH0249288B2 (en) 1990-10-29
SE8700914D0 (en) 1987-03-04
DK176481A (en) 1981-10-23
FR2491761B1 (en) 1984-01-06
ES8306378A1 (en) 1983-06-01
FR2491761A1 (en) 1982-04-16
BE888472A (en) 1981-08-17
NL192111C (en) 1997-02-04
NO811346L (en) 1981-10-23
LU83307A1 (en) 1981-07-24
JPH01301692A (en) 1989-12-05
GB2144409B (en) 1985-09-11
GB2144409A (en) 1985-03-06
NL192111B (en) 1996-10-01
SE8700913L (en) 1987-03-04
CH650514A5 (en) 1985-07-31
DK159453B (en) 1990-10-15
SE460198B (en) 1989-09-18
GB2144038B (en) 1985-08-29
GB2074446B (en) 1985-04-11

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19970422