IT1193529B - ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE - Google Patents

ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE

Info

Publication number
IT1193529B
IT1193529B IT21550/80A IT2155080A IT1193529B IT 1193529 B IT1193529 B IT 1193529B IT 21550/80 A IT21550/80 A IT 21550/80A IT 2155080 A IT2155080 A IT 2155080A IT 1193529 B IT1193529 B IT 1193529B
Authority
IT
Italy
Prior art keywords
adenosinic
inflammatory
derivatives
contain
active principle
Prior art date
Application number
IT21550/80A
Other languages
Italian (it)
Other versions
IT8021550A0 (en
Inventor
Giorgio Stramentioli
Original Assignee
Bioresearch Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch Srl filed Critical Bioresearch Srl
Publication of IT8021550A0 publication Critical patent/IT8021550A0/en
Priority to IT21550/80A priority Critical patent/IT1193529B/en
Priority to BE0/204529A priority patent/BE888472A/en
Priority to SE8102489A priority patent/SE460198B/en
Priority to LU83307A priority patent/LU83307A1/en
Priority to AR285020A priority patent/AR231144A1/en
Priority to NO811346A priority patent/NO150515C/en
Priority to JP5930181A priority patent/JPS56166117A/en
Priority to DK176481A priority patent/DK159453C/en
Priority to ES501539A priority patent/ES501539A0/en
Priority to CA000375784A priority patent/CA1198105A/en
Priority to DE19813116067 priority patent/DE3116067A1/en
Priority to GB8112428A priority patent/GB2074446B/en
Priority to CH4716/84A priority patent/CH650514A5/en
Priority to MX10149781U priority patent/MX6553E/en
Priority to FR8107992A priority patent/FR2491761A1/en
Priority to NL8101984A priority patent/NL192111C/en
Priority to CH263281A priority patent/CH645544A5/en
Priority to FI811249A priority patent/FI70227C/en
Priority to ES511039A priority patent/ES511039A0/en
Priority to GB08321947A priority patent/GB2144409B/en
Priority to FI834113A priority patent/FI68629C/en
Priority to DK25184A priority patent/DK163518C/en
Priority to NO840343A priority patent/NO157863C/en
Priority to GB08413454A priority patent/GB2144038B/en
Priority to CA000490761A priority patent/CA1209915A/en
Priority to SE8700913A priority patent/SE466238B/en
Priority to SE8700914A priority patent/SE464635B/en
Application granted granted Critical
Publication of IT1193529B publication Critical patent/IT1193529B/en
Priority to JP1022771A priority patent/JPH01301692A/en
Priority to MX9203630A priority patent/MX9203630A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
IT21550/80A 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE IT1193529B (en)

Priority Applications (29)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (en) 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE
BE0/204529A BE888472A (en) 1980-04-22 1981-04-17 PHARMACEUTICAL COMPOSITIONS BASED ON ADENOSINE DERIVATIVES AND THEIR PREPARATION,
SE8102489A SE460198B (en) 1980-04-22 1981-04-21 PROCEDURES FOR THE PREPARATION OF 5'-DEOXI-5'-METHYLTIOADENOSINE
LU83307A LU83307A1 (en) 1980-04-22 1981-04-21 ADENOSINE DERIVATIVES WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY, AS WELL AS THERAPEUTIC COMPOSITIONS CONTAINING THESE DERIVATIVES AS ACTIVE INGREDIENT
AR285020A AR231144A1 (en) 1980-04-22 1981-04-21 PROCEDURE FOR THE PREPARATION OF 5'-DESOXI-5'-METHYLTICADENOSINE WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY
NO811346A NO150515C (en) 1980-04-22 1981-04-21 PROCEDURE FOR PREPARING 5`-DEOXY-5`-METHYLTHIOADENOSINE
JP5930181A JPS56166117A (en) 1980-04-22 1981-04-21 Antiinflammatory and analgesic adenosine derivative and therapeutical composition containing it as effective component
DK176481A DK159453C (en) 1980-04-22 1981-04-21 METHOD FOR PREPARING 5'-DEOXY-5'-METHYLTHIOADENOSINE
ES501539A ES501539A0 (en) 1980-04-22 1981-04-21 A PROCEDURE FOR THE PREPARATION OF ADENOSINE DERIVATIVES
CA000375784A CA1198105A (en) 1980-04-22 1981-04-21 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle
FR8107992A FR2491761A1 (en) 1980-04-22 1981-04-22 ADENOSINE DERIVATIVES WITH ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY AND THERAPEUTIC COMPOSITIONS CONTAINING THE SAME AS ACTIVE INGREDIENTS
GB8112428A GB2074446B (en) 1980-04-22 1981-04-22 Adenosine derivatives of antiinflammatory and analgesic activity and therapeutic compositions containing them
CH4716/84A CH650514A5 (en) 1980-04-22 1981-04-22 METHOD FOR PRODUCING 5'-DESOXY-5'-METHYLTHIOADENOSINE.
MX10149781U MX6553E (en) 1980-04-22 1981-04-22 PROCEDURE FOR PREPARING 5'-DESOXI-5'-METHYLTHIOADENOSINE
DE19813116067 DE3116067A1 (en) 1980-04-22 1981-04-22 THERAPEUTIC COMPOSITIONS WITH PAIN-RELEASING AND ANTI-INFLAMMATORY PROPERTIES THAT CONTAIN ADENOS IN DERIVATIVES AS ACTIVE INGREDIENTS
NL8101984A NL192111C (en) 1980-04-22 1981-04-22 Drug preparation with anti-inflammatory effect.
CH263281A CH645544A5 (en) 1980-04-22 1981-04-22 THERAPEUTIC, ADENOSINE DERIVATIVES WITH ANTI-INFLAMMATORY, ANALGETIC AND ANTIPYRETIC EFFECTIVENESS.
FI811249A FI70227C (en) 1980-04-22 1981-04-22 ADJUSTMENT OF THERAPEUTIC ADJUSTMENT
ES511039A ES511039A0 (en) 1980-04-22 1982-04-01 "A PROCEDURE FOR THE PREPARATION OF ADENOSINE DERIVATIVES".
GB08321947A GB2144409B (en) 1980-04-22 1983-08-15 Preparation of 5'-deoxy-5'-methylthioadenosine
FI834113A FI68629C (en) 1980-04-22 1983-11-09 FOERFARANDE FOER FRAMSTAELLNING AV 5'-DEOXY-5'-METHYLTIOADENOSIN
DK25184A DK163518C (en) 1980-04-22 1984-01-20 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE ADENOSIN DERIVATIVES
NO840343A NO157863C (en) 1980-04-22 1984-01-30 ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE ADENOSIN DERIVATIVES.
GB08413454A GB2144038B (en) 1980-04-22 1984-05-25 Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them
CA000490761A CA1209915A (en) 1980-04-22 1985-09-13 Adenosine derivatives of antiinflammatory and analgesic activity, and therapeutic compositions which contain them as their active principle
SE8700913A SE466238B (en) 1980-04-22 1987-03-04 THERAPEUTIC COMPOSITION CONTAINING ADENOSIN DERIVATIVES
SE8700914A SE464635B (en) 1980-04-22 1987-03-04 USE OF AN ADENOSIN DERIVATIVE FOR THE PREPARATION OF A MEDICINE FOR TREATMENT OF INFLAMMATION, PAIN AND FEBRUARY
JP1022771A JPH01301692A (en) 1980-04-22 1989-02-02 Novel production of 5'-deoxy-5'- methylthioadenosine
MX9203630A MX9203630A (en) 1980-04-22 1992-06-26 DERIVATIVES OF ADENOSINE AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE OF ANALGESIC AND ANTI-INFLAMMATORY ACTIVITY.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (en) 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE

Publications (2)

Publication Number Publication Date
IT8021550A0 IT8021550A0 (en) 1980-04-22
IT1193529B true IT1193529B (en) 1988-07-08

Family

ID=11183457

Family Applications (1)

Application Number Title Priority Date Filing Date
IT21550/80A IT1193529B (en) 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE

Country Status (17)

Country Link
JP (2) JPS56166117A (en)
AR (1) AR231144A1 (en)
BE (1) BE888472A (en)
CA (1) CA1198105A (en)
CH (2) CH650514A5 (en)
DE (1) DE3116067A1 (en)
DK (1) DK159453C (en)
ES (2) ES501539A0 (en)
FI (1) FI70227C (en)
FR (1) FR2491761A1 (en)
GB (3) GB2074446B (en)
IT (1) IT1193529B (en)
LU (1) LU83307A1 (en)
MX (1) MX9203630A (en)
NL (1) NL192111C (en)
NO (1) NO150515C (en)
SE (3) SE460198B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (en) * 1984-12-06 1987-08-26 Bioresearch Spa SALTS OF 5'-METHYLLIUM-5'-DEOXYDENOSINE WITH LONG ALCHYLIC CHAIN SULPHONIC ACIDS
IT1227049B (en) * 1988-07-29 1991-03-14 Bioresearch Spa USE OF ADENOSINIC DERIVATIVES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS HAVING IMMUNOSTIMULATING ACTIVITIES.
JPH0497287A (en) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd Picture display integrated circuit
ATE442854T1 (en) 2005-03-17 2009-10-15 Proyecto Biomedicina Cima Sl USE OF 5'-METHYLTHIOADENOSINE FOR THE PREVENTION AND/OR TREATMENT OF AUTOIMMUNE DISEASES AND/OR TRANSPLANT REJECTION
ES2259552B1 (en) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. EMPLOYMENT OF 5'-METHYLTIOENENINE (MTA) IN THE PREVENTION AND / OR TREATMENT OF AUTOIMMUNE DISEASES AND / OR REPLACEMENT OF TRANSPLANTS.
DE102010027595A1 (en) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Clinical application of adenosine derivative, preferably (dihydroxyphenyl)ethyl-amino-purin-9-yl-(hydroxymethyl)oxolane-diol, for reducing body temperature during impending ischemia of brain vessels, which occur during heart attacks
DE102011005232A1 (en) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosine and its derivatives for use in pain therapy
JP6226962B2 (en) * 2013-04-05 2017-11-08 ライオン株式会社 Non-REM sleep enhancer, deep sleep enhancer, natural sleep inducer, and early sleep delta power enhancer
CN105101974B (en) * 2013-04-05 2018-07-03 狮王株式会社 Internal composition
JP6294870B2 (en) * 2013-04-05 2018-03-14 ライオン株式会社 Sleep-promoting agent comprising yeast culture as active ingredient, oral composition for promoting sleep, and food composition for promoting sleep

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (en) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Process for the preparation of new 5'-sulfoxides of nucleosides
DE1545645A1 (en) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Process for the preparation of disubstituted adenosine derivatives
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast
FR2313937A1 (en) * 1975-06-09 1977-01-07 Anvar DRUG BASED ON 5 'THIOETHERS OF ADENOSINE
FR2424027A1 (en) * 1978-04-28 1979-11-23 Merieux Inst NEW MEDICINAL PRODUCT, IN PARTICULAR SEDATIVE AND SLEEP INDUCER AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Also Published As

Publication number Publication date
LU83307A1 (en) 1981-07-24
BE888472A (en) 1981-08-17
DE3116067C2 (en) 1992-12-17
DK159453C (en) 1991-03-18
NL8101984A (en) 1981-11-16
GB2144409B (en) 1985-09-11
MX9203630A (en) 1992-09-01
FR2491761B1 (en) 1984-01-06
AR231144A1 (en) 1984-09-28
SE8700913L (en) 1987-03-04
CH645544A5 (en) 1984-10-15
DE3116067A1 (en) 1982-03-11
SE464635B (en) 1991-05-27
CH650514A5 (en) 1985-07-31
SE8700913D0 (en) 1987-03-04
GB2074446B (en) 1985-04-11
SE8102489L (en) 1981-10-23
JPH0246599B2 (en) 1990-10-16
JPH01301692A (en) 1989-12-05
SE8700914L (en) 1987-03-04
NO811346L (en) 1981-10-23
DK159453B (en) 1990-10-15
CA1198105A (en) 1985-12-17
NO150515B (en) 1984-07-23
NL192111C (en) 1997-02-04
NL192111B (en) 1996-10-01
FR2491761A1 (en) 1982-04-16
JPS56166117A (en) 1981-12-21
JPH0249288B2 (en) 1990-10-29
GB8321947D0 (en) 1983-09-14
DK176481A (en) 1981-10-23
FI70227B (en) 1986-02-28
FI811249L (en) 1981-10-23
IT8021550A0 (en) 1980-04-22
FI70227C (en) 1986-09-15
SE460198B (en) 1989-09-18
ES8306378A1 (en) 1983-06-01
NO150515C (en) 1984-10-31
SE466238B (en) 1992-01-20
GB2144409A (en) 1985-03-06
ES511039A0 (en) 1983-06-01
GB8413454D0 (en) 1984-07-04
GB2144038B (en) 1985-08-29
SE8700914D0 (en) 1987-03-04
GB2074446A (en) 1981-11-04
ES8206551A1 (en) 1982-08-16
ES501539A0 (en) 1982-08-16
GB2144038A (en) 1985-02-27

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960429