GB2144038B - Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them - Google Patents

Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them

Info

Publication number
GB2144038B
GB2144038B GB08413454A GB8413454A GB2144038B GB 2144038 B GB2144038 B GB 2144038B GB 08413454 A GB08413454 A GB 08413454A GB 8413454 A GB8413454 A GB 8413454A GB 2144038 B GB2144038 B GB 2144038B
Authority
GB
United Kingdom
Prior art keywords
inflammatory
compositions containing
therapeutic compositions
analgesic activity
adenosine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08413454A
Other versions
GB8413454D0 (en
GB2144038A (en
Inventor
Giorgio Stramentinoli
Federico Gennari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioresearch SRL
Original Assignee
Bioresearch SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioresearch SRL filed Critical Bioresearch SRL
Publication of GB8413454D0 publication Critical patent/GB8413454D0/en
Publication of GB2144038A publication Critical patent/GB2144038A/en
Application granted granted Critical
Publication of GB2144038B publication Critical patent/GB2144038B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
GB08413454A 1980-04-22 1984-05-25 Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them Expired GB2144038B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21550/80A IT1193529B (en) 1980-04-22 1980-04-22 ADENOSINIC DERIVATIVES FOR ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES AND THERAPEUTIC COMPOSITIONS THAT CONTAIN THEM AS AN ACTIVE PRINCIPLE

Publications (3)

Publication Number Publication Date
GB8413454D0 GB8413454D0 (en) 1984-07-04
GB2144038A GB2144038A (en) 1985-02-27
GB2144038B true GB2144038B (en) 1985-08-29

Family

ID=11183457

Family Applications (3)

Application Number Title Priority Date Filing Date
GB8112428A Expired GB2074446B (en) 1980-04-22 1981-04-22 Adenosine derivatives of antiinflammatory and analgesic activity and therapeutic compositions containing them
GB08321947A Expired GB2144409B (en) 1980-04-22 1983-08-15 Preparation of 5'-deoxy-5'-methylthioadenosine
GB08413454A Expired GB2144038B (en) 1980-04-22 1984-05-25 Adenosine derivatives of anti-inflammatory and analgesic activity and therapeutic compositions containing them

Family Applications Before (2)

Application Number Title Priority Date Filing Date
GB8112428A Expired GB2074446B (en) 1980-04-22 1981-04-22 Adenosine derivatives of antiinflammatory and analgesic activity and therapeutic compositions containing them
GB08321947A Expired GB2144409B (en) 1980-04-22 1983-08-15 Preparation of 5'-deoxy-5'-methylthioadenosine

Country Status (17)

Country Link
JP (2) JPS56166117A (en)
AR (1) AR231144A1 (en)
BE (1) BE888472A (en)
CA (1) CA1198105A (en)
CH (2) CH650514A5 (en)
DE (1) DE3116067A1 (en)
DK (1) DK159453C (en)
ES (2) ES501539A0 (en)
FI (1) FI70227C (en)
FR (1) FR2491761A1 (en)
GB (3) GB2074446B (en)
IT (1) IT1193529B (en)
LU (1) LU83307A1 (en)
MX (1) MX9203630A (en)
NL (1) NL192111C (en)
NO (1) NO150515C (en)
SE (3) SE460198B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1177373B (en) * 1984-12-06 1987-08-26 Bioresearch Spa SALTS OF 5'-METHYLLIUM-5'-DEOXYDENOSINE WITH LONG ALCHYLIC CHAIN SULPHONIC ACIDS
IT1227049B (en) * 1988-07-29 1991-03-14 Bioresearch Spa USE OF ADENOSINIC DERIVATIVES FOR THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS HAVING IMMUNOSTIMULATING ACTIVITIES.
JPH0497287A (en) * 1990-08-10 1992-03-30 Nec Ic Microcomput Syst Ltd Picture display integrated circuit
ATE442854T1 (en) 2005-03-17 2009-10-15 Proyecto Biomedicina Cima Sl USE OF 5'-METHYLTHIOADENOSINE FOR THE PREVENTION AND/OR TREATMENT OF AUTOIMMUNE DISEASES AND/OR TRANSPLANT REJECTION
ES2259552B1 (en) * 2005-03-17 2007-06-16 Proyecto De Biomedicina Cima, S.L. EMPLOYMENT OF 5'-METHYLTIOENENINE (MTA) IN THE PREVENTION AND / OR TREATMENT OF AUTOIMMUNE DISEASES AND / OR REPLACEMENT OF TRANSPLANTS.
DE102010027595A1 (en) * 2010-07-23 2012-01-26 Helmut Vorbrüggen Clinical application of adenosine derivative, preferably (dihydroxyphenyl)ethyl-amino-purin-9-yl-(hydroxymethyl)oxolane-diol, for reducing body temperature during impending ischemia of brain vessels, which occur during heart attacks
DE102011005232A1 (en) * 2011-03-08 2012-09-13 AristoCon GmbH & Co. KG Adenosine and its derivatives for use in pain therapy
JP6226962B2 (en) * 2013-04-05 2017-11-08 ライオン株式会社 Non-REM sleep enhancer, deep sleep enhancer, natural sleep inducer, and early sleep delta power enhancer
CN105101974B (en) * 2013-04-05 2018-07-03 狮王株式会社 Internal composition
JP6294870B2 (en) * 2013-04-05 2018-03-14 ライオン株式会社 Sleep-promoting agent comprising yeast culture as active ingredient, oral composition for promoting sleep, and food composition for promoting sleep

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1259341B (en) * 1962-12-22 1968-01-25 Boehringer & Soehne Gmbh Process for the preparation of new 5'-sulfoxides of nucleosides
DE1545645A1 (en) * 1965-12-06 1969-08-21 Boehringer Mannheim Gmbh Process for the preparation of disubstituted adenosine derivatives
GB1436509A (en) * 1973-11-27 1976-05-19 Ajinomoto Kk Method for producing s-adenosylmethionine or methylthioadenosine from yeast
FR2313937A1 (en) * 1975-06-09 1977-01-07 Anvar DRUG BASED ON 5 'THIOETHERS OF ADENOSINE
FR2424027A1 (en) * 1978-04-28 1979-11-23 Merieux Inst NEW MEDICINAL PRODUCT, IN PARTICULAR SEDATIVE AND SLEEP INDUCER AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT

Also Published As

Publication number Publication date
LU83307A1 (en) 1981-07-24
BE888472A (en) 1981-08-17
DE3116067C2 (en) 1992-12-17
DK159453C (en) 1991-03-18
NL8101984A (en) 1981-11-16
GB2144409B (en) 1985-09-11
MX9203630A (en) 1992-09-01
FR2491761B1 (en) 1984-01-06
AR231144A1 (en) 1984-09-28
SE8700913L (en) 1987-03-04
CH645544A5 (en) 1984-10-15
DE3116067A1 (en) 1982-03-11
SE464635B (en) 1991-05-27
CH650514A5 (en) 1985-07-31
SE8700913D0 (en) 1987-03-04
GB2074446B (en) 1985-04-11
SE8102489L (en) 1981-10-23
JPH0246599B2 (en) 1990-10-16
JPH01301692A (en) 1989-12-05
SE8700914L (en) 1987-03-04
NO811346L (en) 1981-10-23
DK159453B (en) 1990-10-15
CA1198105A (en) 1985-12-17
NO150515B (en) 1984-07-23
NL192111C (en) 1997-02-04
NL192111B (en) 1996-10-01
FR2491761A1 (en) 1982-04-16
JPS56166117A (en) 1981-12-21
JPH0249288B2 (en) 1990-10-29
GB8321947D0 (en) 1983-09-14
DK176481A (en) 1981-10-23
FI70227B (en) 1986-02-28
FI811249L (en) 1981-10-23
IT8021550A0 (en) 1980-04-22
FI70227C (en) 1986-09-15
SE460198B (en) 1989-09-18
ES8306378A1 (en) 1983-06-01
NO150515C (en) 1984-10-31
SE466238B (en) 1992-01-20
GB2144409A (en) 1985-03-06
ES511039A0 (en) 1983-06-01
GB8413454D0 (en) 1984-07-04
IT1193529B (en) 1988-07-08
SE8700914D0 (en) 1987-03-04
GB2074446A (en) 1981-11-04
ES8206551A1 (en) 1982-08-16
ES501539A0 (en) 1982-08-16
GB2144038A (en) 1985-02-27

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 19970422