RU2195332C2 - Способ и устройство для использования опосредованной электропорообразованием доставки лекарственных препаратов и генов - Google Patents

Способ и устройство для использования опосредованной электропорообразованием доставки лекарственных препаратов и генов Download PDF

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RU2195332C2
RU2195332C2 RU99109111/14A RU99109111A RU2195332C2 RU 2195332 C2 RU2195332 C2 RU 2195332C2 RU 99109111/14 A RU99109111/14 A RU 99109111/14A RU 99109111 A RU99109111 A RU 99109111A RU 2195332 C2 RU2195332 C2 RU 2195332C2
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Russia
Prior art keywords
electrode
applicator
needles
therapy
tissue
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RU99109111/14A
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English (en)
Russian (ru)
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RU99109111A (ru
Inventor
Гунтер А. ХОФМАНН
Сукхенду Б. ДЕВ
Стивен С. ДИММЕР
Джеффри И. ЛЕВАТТЕР
Гурвиндер С. НАНДА
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Дженетроникс, Инк.
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327—Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0502—Skin piercing electrodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Electrotherapy Devices (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU99109111/14A 1997-08-01 1998-07-31 Способ и устройство для использования опосредованной электропорообразованием доставки лекарственных препаратов и генов RU2195332C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/905,240 US6055453A (en) 1997-08-01 1997-08-01 Apparatus for addressing needle array electrodes for electroporation therapy
US08/905,240 1997-08-01

Publications (2)

Publication Number Publication Date
RU99109111A RU99109111A (ru) 2001-04-27
RU2195332C2 true RU2195332C2 (ru) 2002-12-27

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RU99109111/14A RU2195332C2 (ru) 1997-08-01 1998-07-31 Способ и устройство для использования опосредованной электропорообразованием доставки лекарственных препаратов и генов

Country Status (13)

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US (5) US6055453A (enExample)
EP (1) EP0999867B1 (enExample)
JP (2) JP2000503586A (enExample)
KR (1) KR100756252B1 (enExample)
CN (2) CN1768873B (enExample)
AT (1) ATE480294T1 (enExample)
AU (1) AU734343B2 (enExample)
BR (1) BR9806069A (enExample)
CA (1) CA2268026C (enExample)
DE (1) DE69841888D1 (enExample)
RU (1) RU2195332C2 (enExample)
TW (1) TW396043B (enExample)
WO (1) WO1999006101A1 (enExample)

Cited By (2)

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RU2252793C1 (ru) * 2004-02-02 2005-05-27 Карасев Александр Александрович Электродное устройство
WO2012178095A1 (en) * 2011-06-22 2012-12-27 Ifluidics, Inc. Electromotive system for high-throughput screening

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