RU2138253C1 - Лекарственное средство с замедленным высвобождением активнодействующего вещества - Google Patents

Лекарственное средство с замедленным высвобождением активнодействующего вещества Download PDF

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Publication number
RU2138253C1
RU2138253C1 RU94032150A RU94032150A RU2138253C1 RU 2138253 C1 RU2138253 C1 RU 2138253C1 RU 94032150 A RU94032150 A RU 94032150A RU 94032150 A RU94032150 A RU 94032150A RU 2138253 C1 RU2138253 C1 RU 2138253C1
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Russia
Prior art keywords
active substance
cellulose
release
pharmaceutically acceptable
biologically active
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RU94032150A
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English (en)
Russian (ru)
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RU94032150A (ru
Inventor
Хайнрих Антониус Бартоломойс Иоханес
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Грюненталь Гмбх
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/2853—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
    • A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
RU94032150A 1993-09-03 1994-09-01 Лекарственное средство с замедленным высвобождением активнодействующего вещества RU2138253C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4329794.3 1993-09-03
DE4329794A DE4329794C2 (de) 1993-09-03 1993-09-03 Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung

Publications (2)

Publication Number Publication Date
RU94032150A RU94032150A (ru) 1996-11-10
RU2138253C1 true RU2138253C1 (ru) 1999-09-27

Family

ID=6496771

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94032150A RU2138253C1 (ru) 1993-09-03 1994-09-01 Лекарственное средство с замедленным высвобождением активнодействующего вещества

Country Status (28)

Country Link
US (1) US5601842A (show.php)
EP (1) EP0642788B1 (show.php)
JP (1) JP3954117B2 (show.php)
KR (1) KR100325494B1 (show.php)
CN (1) CN1092956C (show.php)
AT (1) ATE166575T1 (show.php)
AU (1) AU671384B2 (show.php)
BR (1) BR9403030A (show.php)
CA (1) CA2131350C (show.php)
CO (1) CO4290295A1 (show.php)
CZ (1) CZ288832B6 (show.php)
DE (2) DE4329794C2 (show.php)
DK (1) DK0642788T3 (show.php)
EC (1) ECSP941148A (show.php)
ES (1) ES2119034T3 (show.php)
FI (1) FI113336B (show.php)
HK (1) HK1010447A1 (show.php)
HU (1) HU215955B (show.php)
IL (1) IL109800A (show.php)
LT (1) LT3664B (show.php)
MY (1) MY111754A (show.php)
PE (1) PE10195A1 (show.php)
PL (1) PL177315B1 (show.php)
RU (1) RU2138253C1 (show.php)
SI (1) SI0642788T1 (show.php)
UA (1) UA26455C2 (show.php)
UY (1) UY23804A1 (show.php)
ZA (1) ZA946775B (show.php)

Cited By (5)

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RU2174836C1 (ru) * 2000-12-15 2001-10-20 Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин" Фармацевтическая композиция, обладающая анальгезирующим действием
RU2201223C2 (ru) * 1996-07-25 2003-03-27 Виатрис Гмбх Унд Ко. Кг Фармацевтическая композиция из множества субъединиц и способ ее получения
RU2285519C2 (ru) * 2000-09-29 2006-10-20 Солвей Фармасьютикалс Б.В. Фармацевтическая композиция с пролонгированным высвобождением, независимым от ионной силы
RU2423107C2 (ru) * 2005-03-11 2011-07-10 Пх Энд Т С.П.А. Составы с контролируемым высвобождением альфузозина
RU2445081C2 (ru) * 2005-09-15 2012-03-20 Грюненталь Гмбх Дюрантная лекарственная форма, содержащая 3-(2-диметиламинометилциклогексил)фенол

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US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
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IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
KR100354702B1 (ko) 1993-11-23 2002-12-28 유로-셀티크 소시에떼 아노뉨 약학조성물의제조방법및서방형조성물
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US5843480A (en) 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
DE19530575A1 (de) * 1995-08-19 1997-02-20 Gruenenthal Gmbh Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
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RU2445081C2 (ru) * 2005-09-15 2012-03-20 Грюненталь Гмбх Дюрантная лекарственная форма, содержащая 3-(2-диметиламинометилциклогексил)фенол

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IL109800A0 (en) 1994-08-26
ES2119034T3 (es) 1998-10-01
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CA2131350C (en) 2005-08-16
EP0642788A3 (show.php) 1995-04-12
FI113336B (fi) 2004-04-15
HU9402478D0 (en) 1994-10-28
ECSP941148A (es) 1995-01-16
KR950007841A (ko) 1995-04-15
FI944035A0 (fi) 1994-09-02
IL109800A (en) 2000-06-01
DE4329794C2 (de) 1997-09-18
UA26455C2 (uk) 1999-08-30
AU671384B2 (en) 1996-08-22
PL304860A1 (en) 1995-03-06
ZA946775B (en) 1995-04-21
JPH07196482A (ja) 1995-08-01
BR9403030A (pt) 1995-05-02
LTIP2033A (en) 1995-03-27
CN1106656A (zh) 1995-08-16
PE10195A1 (es) 1995-03-31
MY111754A (en) 2000-12-30
US5601842A (en) 1997-02-11
PL177315B1 (pl) 1999-10-29
EP0642788A2 (de) 1995-03-15
CZ288832B6 (cs) 2001-09-12
EP0642788B1 (de) 1998-05-27
DE59406075D1 (de) 1998-07-02
DE4329794A1 (de) 1995-03-09
JP3954117B2 (ja) 2007-08-08
KR100325494B1 (ko) 2002-06-22
CA2131350A1 (en) 1995-03-04
SI0642788T1 (en) 1998-08-31
LT3664B (en) 1996-01-25
CO4290295A1 (es) 1996-04-17
HK1010447A1 (en) 1999-06-17
ATE166575T1 (de) 1998-06-15
HUT70438A (en) 1995-10-30
RU94032150A (ru) 1996-11-10
DK0642788T3 (da) 1999-01-18
FI944035L (fi) 1995-03-04
HU215955B (hu) 1999-03-29
CZ214094A3 (en) 1995-03-15
AU7280394A (en) 1995-03-16
CN1092956C (zh) 2002-10-23

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