US5266331A
(en)
*
|
1991-11-27 |
1993-11-30 |
Euroceltique, S.A. |
Controlled release oxycodone compositions
|
US5958459A
(en)
*
|
1991-12-24 |
1999-09-28 |
Purdue Pharma L.P. |
Opioid formulations having extended controlled released
|
US5478577A
(en)
*
|
1993-11-23 |
1995-12-26 |
Euroceltique, S.A. |
Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
|
US5968551A
(en)
|
1991-12-24 |
1999-10-19 |
Purdue Pharma L.P. |
Orally administrable opioid formulations having extended duration of effect
|
US20080075781A1
(en)
*
|
1992-11-25 |
2008-03-27 |
Purdue Pharma Lp |
Controlled release oxycodone compositions
|
IL119660A
(en)
*
|
1993-05-10 |
2002-09-12 |
Euro Celtique Sa |
Controlled release formulation comprising tramadol
|
US20070275062A1
(en)
*
|
1993-06-18 |
2007-11-29 |
Benjamin Oshlack |
Controlled release oxycodone compositions
|
US7740881B1
(en)
|
1993-07-01 |
2010-06-22 |
Purdue Pharma Lp |
Method of treating humans with opioid formulations having extended controlled release
|
IL110014A
(en)
*
|
1993-07-01 |
1999-11-30 |
Euro Celtique Sa |
Solid controlled-release oral dosage forms of opioid analgesics
|
US5879705A
(en)
*
|
1993-07-27 |
1999-03-09 |
Euro-Celtique S.A. |
Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
|
KR100354702B1
(ko)
|
1993-11-23 |
2002-12-28 |
유로-셀티크 소시에떼 아노뉨 |
약학조성물의제조방법및서방형조성물
|
US5891471A
(en)
|
1993-11-23 |
1999-04-06 |
Euro-Celtique, S.A. |
Pharmaceutical multiparticulates
|
US5843480A
(en)
|
1994-03-14 |
1998-12-01 |
Euro-Celtique, S.A. |
Controlled release diamorphine formulation
|
GB9422154D0
(en)
|
1994-11-03 |
1994-12-21 |
Euro Celtique Sa |
Pharmaceutical compositions and method of producing the same
|
US5965161A
(en)
|
1994-11-04 |
1999-10-12 |
Euro-Celtique, S.A. |
Extruded multi-particulates
|
DE19530575A1
(de)
*
|
1995-08-19 |
1997-02-20 |
Gruenenthal Gmbh |
Schnell zerfallende Arzneiform von Tramadol oder einem Tramadolsalz
|
GB9519363D0
(en)
|
1995-09-22 |
1995-11-22 |
Euro Celtique Sa |
Pharmaceutical formulation
|
US6159501A
(en)
*
|
1996-03-08 |
2000-12-12 |
Nycomed Danmark A/S |
Modified release multiple-units dosage composition for release of opioid compounds
|
DE19712398A1
(de)
*
|
1997-03-25 |
1998-10-01 |
Gruenenthal Gmbh |
Orale Anwendung von (+)-0-Demethyltramadol als Schmerzmittel
|
PT1009387E
(pt)
*
|
1997-07-02 |
2006-08-31 |
Euro Celtique Sa |
Formulacoes estabilizadas de libertacao controlada de tramadol
|
US6156342A
(en)
*
|
1998-05-26 |
2000-12-05 |
Andex Pharmaceuticals, Inc. |
Controlled release oral dosage form
|
DE29818454U1
(de)
*
|
1998-10-15 |
1999-01-14 |
Euro Celtique Sa |
Opioid-Analgetikum
|
US6806294B2
(en)
|
1998-10-15 |
2004-10-19 |
Euro-Celtique S.A. |
Opioid analgesic
|
WO2000040205A2
(en)
*
|
1999-01-05 |
2000-07-13 |
Copley Pharmaceutical Inc. |
Sustained release formulation with reduced moisture sensitivity
|
DE19901692C2
(de)
*
|
1999-01-18 |
2002-06-20 |
Gruenenthal Gmbh |
Verfahren zur Herstellung von Pellets mit einem Gehalt von bis zu 90 Gew.% eines pharmazeutischen Wirkstoffes
|
DE19918325A1
(de)
|
1999-04-22 |
2000-10-26 |
Euro Celtique Sa |
Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
|
CA2388560A1
(en)
*
|
1999-08-31 |
2001-03-08 |
Grunenthal Gmbh |
Sustained-release form of administration containing tramadol saccharinate
|
US10179130B2
(en)
|
1999-10-29 |
2019-01-15 |
Purdue Pharma L.P. |
Controlled release hydrocodone formulations
|
EP2295043A1
(en)
|
1999-10-29 |
2011-03-16 |
Euro-Celtique S.A. |
Controlled release hydrocodone formulations
|
SK285128B6
(sk)
*
|
1999-12-28 |
2006-07-07 |
Zentiva, A. S. |
Liečivý prípravok s riadeným uvoľňovaním obsahujúci tramadol hydrochlorid a spôsob jeho prípravy
|
ATE274906T1
(de)
*
|
2000-09-22 |
2004-09-15 |
Smb Technology |
Oral anzuwendende tramadolhaltige teilchen zur einmal täglichen verabreichung
|
CN101317825A
(zh)
|
2000-10-30 |
2008-12-10 |
欧罗赛铁克股份有限公司 |
控释氢可酮制剂
|
DE10108122A1
(de)
*
|
2001-02-21 |
2002-10-02 |
Gruenenthal Gmbh |
Arzneimittel auf Basis von Tramadol
|
EP1397126B9
(en)
*
|
2001-03-16 |
2007-02-21 |
DMI Biosciences, Inc. |
Use of tramadol for delaying ejaculation
|
US20110104214A1
(en)
|
2004-04-15 |
2011-05-05 |
Purdue Pharma L.P. |
Once-a-day oxycodone formulations
|
UA81224C2
(ru)
|
2001-05-02 |
2007-12-25 |
Euro Celtic S A |
Дозированная форма оксикодона и ее применение
|
PE20030527A1
(es)
*
|
2001-10-24 |
2003-07-26 |
Gruenenthal Chemie |
Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
|
US8128957B1
(en)
|
2002-02-21 |
2012-03-06 |
Valeant International (Barbados) Srl |
Modified release compositions of at least one form of tramadol
|
US20060099249A1
(en)
*
|
2002-02-21 |
2006-05-11 |
Pawan Seth |
Modified release formulations of at least one form of tramadol
|
JP2005526079A
(ja)
*
|
2002-03-15 |
2005-09-02 |
サイプレス バイオサイエンス, インコーポレイテッド |
内蔵痛症候群を処置するためのneおよび5−ht再取り込み阻害剤
|
WO2003080031A1
(en)
*
|
2002-03-22 |
2003-10-02 |
Cilag Ag |
Sustained release formulation of tramadol
|
US7410965B2
(en)
|
2002-05-29 |
2008-08-12 |
Gruenenthal Gmbh |
Delayed release pharmaceutical composition containing 1-dimethyl-amino-3-(3-methoxyphenyl)-2-methyl-pentan-3-ol
|
DE10224108A1
(de)
*
|
2002-05-29 |
2004-01-29 |
Grünenthal GmbH |
1-Dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol enthaltendes Arzneimiitel mit verzögerter Wirkstofffreisetzung
|
US7776314B2
(en)
*
|
2002-06-17 |
2010-08-17 |
Grunenthal Gmbh |
Abuse-proofed dosage system
|
US20050020613A1
(en)
*
|
2002-09-20 |
2005-01-27 |
Alpharma, Inc. |
Sustained release opioid formulations and method of use
|
US8487002B2
(en)
|
2002-10-25 |
2013-07-16 |
Paladin Labs Inc. |
Controlled-release compositions
|
US20060003004A1
(en)
*
|
2002-10-25 |
2006-01-05 |
Collegium Pharmaceutical, Inc. |
Pulsatile release compositions of milnacipran
|
TWI319713B
(en)
|
2002-10-25 |
2010-01-21 |
|
Sustained-release tramadol formulations with 24-hour efficacy
|
US20040121010A1
(en)
*
|
2002-10-25 |
2004-06-24 |
Collegium Pharmaceutical, Inc. |
Pulsatile release compositions of milnacipran
|
EP1592453A1
(en)
*
|
2003-01-28 |
2005-11-09 |
Collegium Pharmaceutical, Inc. |
Multiparticulate compositions of milnacipran for oral administration
|
DE10333835A1
(de)
*
|
2003-07-24 |
2005-03-10 |
Gruenenthal Gmbh |
6-Dimethylaminomethyl-1-(3-methoxy-phenyl)-cyclohexane-1,3-diol enthaltendes Arzneimittel mit verzögerter Wirkstofffreisetzung
|
DE102004032051A1
(de)
*
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
|
DE102005005446A1
(de)
*
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Bruchfeste Darreichungsformen mit retardierter Freisetzung
|
DE102004020220A1
(de)
*
|
2004-04-22 |
2005-11-10 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform
|
US20070048228A1
(en)
*
|
2003-08-06 |
2007-03-01 |
Elisabeth Arkenau-Maric |
Abuse-proofed dosage form
|
DE10336400A1
(de)
|
2003-08-06 |
2005-03-24 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte Darreichungsform
|
DE10361596A1
(de)
*
|
2003-12-24 |
2005-09-29 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
DE502004004205D1
(de)
*
|
2003-08-06 |
2007-08-09 |
Gruenenthal Gmbh |
Gegen missbrauch gesicherte darreichungsform
|
US8075872B2
(en)
|
2003-08-06 |
2011-12-13 |
Gruenenthal Gmbh |
Abuse-proofed dosage form
|
US20060172006A1
(en)
*
|
2003-10-10 |
2006-08-03 |
Vincent Lenaerts |
Sustained-release tramadol formulations with 24-hour clinical efficacy
|
US20050089558A1
(en)
*
|
2003-10-28 |
2005-04-28 |
Alamo Pharmaceuticals, Llc |
Compositions and methods for the co-formulation and administration of tramadol and propoxyphene
|
DE102004032103A1
(de)
*
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte, orale Darreichungsform
|
DE102004032049A1
(de)
|
2004-07-01 |
2006-01-19 |
Grünenthal GmbH |
Gegen Missbrauch gesicherte, orale Darreichungsform
|
DE102005005449A1
(de)
*
|
2005-02-04 |
2006-08-10 |
Grünenthal GmbH |
Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform
|
JP5371427B2
(ja)
*
|
2005-07-07 |
2013-12-18 |
ファーナム・カンパニーズ・インコーポレーテッド |
高水溶性薬剤用徐放性医薬組成物
|
CA2616416A1
(en)
*
|
2005-09-09 |
2007-05-03 |
Labopharm, Inc. |
Trazodone composition for once a day adminisitiation
|
US20090104266A1
(en)
*
|
2005-09-15 |
2009-04-23 |
Tobias Jung |
3-(2-dimethylaminomethylcy clohexyl)phenol retard formulation
|
US8691272B2
(en)
*
|
2005-12-30 |
2014-04-08 |
Intelgenx Corp. |
Multilayer tablet
|
US20070190141A1
(en)
*
|
2006-02-16 |
2007-08-16 |
Aaron Dely |
Extended release opiate composition
|
WO2008011596A2
(en)
*
|
2006-07-21 |
2008-01-24 |
Lab International Srl |
Hydrophilic abuse deterrent delivery system
|
DE102006044694A1
(de)
*
|
2006-09-22 |
2008-03-27 |
Krewel Meuselbach Gmbh |
Perorale feste Schmerzmittelzubereitung
|
WO2008100926A1
(en)
*
|
2007-02-12 |
2008-08-21 |
Dmi Biosciences, Inc. |
Treatment of comorbid premature ejaculation and erectile dysfunction
|
CA2677691C
(en)
|
2007-02-12 |
2012-07-31 |
David Bar-Or |
Reducing side effects of tramadol
|
DE102007011485A1
(de)
*
|
2007-03-07 |
2008-09-11 |
Grünenthal GmbH |
Darreichungsform mit erschwertem Missbrauch
|
RU2469718C2
(ru)
*
|
2007-10-16 |
2012-12-20 |
Лабофарм Инк. |
Двухслойная композиция для непрерывного высвобождения ацетаминофена и трамадола
|
JP5651818B2
(ja)
|
2007-12-17 |
2015-01-14 |
パラディン ラブス インコーポレーテッド |
誤用を防止するための放出制御製剤
|
EP2249811A1
(en)
*
|
2008-01-25 |
2010-11-17 |
Grünenthal GmbH |
Pharmaceutical dosage form
|
HUE030803T2
(en)
*
|
2008-05-09 |
2017-06-28 |
Gruenenthal Gmbh |
Process for the preparation of an intermediate powder formulation and a final solid dosage form using a spraying step \ t
|
US20100003322A1
(en)
*
|
2008-07-03 |
2010-01-07 |
Lai Felix S |
Enteric coated hydrophobic matrix formulation
|
US8486449B2
(en)
|
2008-12-16 |
2013-07-16 |
Paladin Labs Inc. |
Misuse preventative, controlled release formulation
|
EP2456427B1
(en)
|
2009-07-22 |
2015-03-04 |
Grünenthal GmbH |
Hot-melt extruded controlled release dosage form
|
PE20120572A1
(es)
|
2009-07-22 |
2012-06-06 |
Gruenenthal Chemie |
Forma de dosificacion de oxidacion estabilizada resistente a la manipulacion
|
US10610528B2
(en)
|
2009-12-08 |
2020-04-07 |
Intelgenx Corp. |
Solid oral film dosage forms and methods for making same
|
US20110136815A1
(en)
*
|
2009-12-08 |
2011-06-09 |
Horst Zerbe |
Solid oral film dosage forms and methods for making same
|
EP2531176B1
(en)
*
|
2010-02-03 |
2016-09-07 |
Grünenthal GmbH |
Preparation of a powdery pharmaceutical composition by means of an extruder
|
AU2011252040C1
(en)
|
2010-05-10 |
2015-04-02 |
Euro-Celtique S.A. |
Manufacturing of active-free granules and tablets comprising the same
|
US20120009261A1
(en)
|
2010-07-06 |
2012-01-12 |
Grünenthal GmbH |
Novel gastro-retentive dosage forms
|
NZ607392A
(en)
|
2010-09-02 |
2015-03-27 |
Gruenenthal Chemie |
Tamper resistant dosage form comprising inorganic salt
|
PE20131126A1
(es)
|
2010-09-02 |
2013-10-21 |
Gruenenthal Chemie |
Forma de dosificacion resistente a alteracion que comprende un polimero anionico
|
WO2012061779A1
(en)
*
|
2010-11-04 |
2012-05-10 |
Abbott Gmbh & Co. Kg |
Drug formulations
|
EP2736495B1
(en)
|
2011-07-29 |
2017-08-23 |
Grünenthal GmbH |
Tamper-resistant tablet providing immediate drug release
|
DK2736497T3
(da)
|
2011-07-29 |
2017-11-13 |
Gruenenthal Gmbh |
Stød-resistent tablet, der tilvejebringer en øjeblikkelig frigivelse af et lægemiddel.
|
MX356421B
(es)
|
2012-02-28 |
2018-05-29 |
Gruenenthal Gmbh |
Forma de dosificacion resistente a la manipulacion indebida que comprende un compuesto farmacologicamente activo y un polimero anionico.
|
LT2838512T
(lt)
|
2012-04-18 |
2018-11-12 |
GrĆ¼nenthal GmbH |
Pažeidimui atspari ir dozės atpalaidavimo nuokrypiui atspari farmacinė vaisto forma
|
US10064945B2
(en)
|
2012-05-11 |
2018-09-04 |
Gruenenthal Gmbh |
Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc
|
US10154966B2
(en)
|
2013-05-29 |
2018-12-18 |
Grünenthal GmbH |
Tamper-resistant dosage form containing one or more particles
|
MX2015016254A
(es)
|
2013-05-29 |
2016-04-20 |
Gruenenthal Gmbh |
Forma de dosificacion resistente al uso indebido con perfil de liberacion bimodal.
|
KR20160031526A
(ko)
|
2013-07-12 |
2016-03-22 |
그뤼넨탈 게엠베하 |
에틸렌-비닐 아세테이트 중합체를 함유하는 템퍼 내성 투여형
|
CA2931553C
(en)
|
2013-11-26 |
2022-01-18 |
Grunenthal Gmbh |
Preparation of a powdery pharmaceutical composition by means of cryo-milling
|
EP3142646A1
(en)
|
2014-05-12 |
2017-03-22 |
Grünenthal GmbH |
Tamper resistant immediate release capsule formulation comprising tapentadol
|
US9872835B2
(en)
|
2014-05-26 |
2018-01-23 |
Grünenthal GmbH |
Multiparticles safeguarded against ethanolic dose-dumping
|
WO2016170097A1
(en)
|
2015-04-24 |
2016-10-27 |
Grünenthal GmbH |
Tamper-resistant dosage form with immediate release and resistance against solvent extraction
|
WO2017042325A1
(en)
|
2015-09-10 |
2017-03-16 |
Grünenthal GmbH |
Protecting oral overdose with abuse deterrent immediate release formulations
|