RU2016146365A - Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b - Google Patents

Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b Download PDF

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RU2016146365A
RU2016146365A RU2016146365A RU2016146365A RU2016146365A RU 2016146365 A RU2016146365 A RU 2016146365A RU 2016146365 A RU2016146365 A RU 2016146365A RU 2016146365 A RU2016146365 A RU 2016146365A RU 2016146365 A RU2016146365 A RU 2016146365A
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methoxy
ethyl
dihydrobenzo
oxo
carboxamide
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RU2016146365A
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Russian (ru)
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RU2016146365A3 (en:Method
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Сун ЯН
Синчунь Хань
Чжаньго Ван
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Ф. Хоффманн-Ля Рош Аг
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Publication of RU2016146365A publication Critical patent/RU2016146365A/ru
Publication of RU2016146365A3 publication Critical patent/RU2016146365A3/ru

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D455/00Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C07D455/06Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine containing benzo [a] quinolizine ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
RU2016146365A 2014-05-13 2015-05-11 Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b RU2016146365A (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
CNPCT/CN2014/077354 2014-05-13
CN2014077354 2014-05-13
CNPCT/CN2015/074462 2015-03-18
CN2015074462 2015-03-18
PCT/EP2015/060284 WO2015173164A1 (en) 2014-05-13 2015-05-11 Novel dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection

Publications (2)

Publication Number Publication Date
RU2016146365A true RU2016146365A (ru) 2018-06-19
RU2016146365A3 RU2016146365A3 (en:Method) 2018-06-19

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RU2016146365A RU2016146365A (ru) 2014-05-13 2015-05-11 Новые дигидрохинолизиноны для лечения и профилактики заражения вирусом гепатита b

Country Status (9)

Country Link
US (1) US9920049B2 (en:Method)
EP (1) EP3143020B1 (en:Method)
JP (1) JP6568106B2 (en:Method)
KR (1) KR20160148715A (en:Method)
CN (1) CN106459032B (en:Method)
CA (1) CA2948080A1 (en:Method)
MX (1) MX2016014728A (en:Method)
RU (1) RU2016146365A (en:Method)
WO (1) WO2015173164A1 (en:Method)

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