|
WO2010020675A1
(en)
|
2008-08-22 |
2010-02-25 |
Novartis Ag |
Pyrrolopyrimidine compounds as cdk inhibitors
|
|
CN102458443A
(zh)
|
2009-05-13 |
2012-05-16 |
北卡罗来纳大学查珀尔希尔分校 |
细胞周期蛋白依赖性激酶抑制剂及使用方法
|
|
UY33227A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina como inhibidores de la cdk4/6
|
|
UY33226A
(es)
*
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina deuterada como inhibidores de la cdk4/6
|
|
ES2689177T3
(es)
*
|
2010-04-13 |
2018-11-08 |
Novartis Ag |
Combinación que comprende un inhibidor de cinasa 4 dependiente de ciclina o cinasa dependiente de ciclina (CDK4/6) y un inhibidor de mTOR para tratar cáncer
|
|
WO2012024500A1
(en)
|
2010-08-18 |
2012-02-23 |
Life Technologies Corporation |
Chemical coating of microwell for electrochemical detection device
|
|
AU2011323739B2
(en)
*
|
2010-10-25 |
2016-05-12 |
Pharmacosmos Holding A/S |
CDK inhibitors
|
|
US8691830B2
(en)
|
2010-10-25 |
2014-04-08 |
G1 Therapeutics, Inc. |
CDK inhibitors
|
|
AR083797A1
(es)
*
|
2010-11-10 |
2013-03-20 |
Novartis Ag |
Succinato de dimetil-amida del acido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]pirimidin-6-carboxilico, proceso para prepararla, intermediarios de dicha sintesis y proceso de preparacion de los mismos
|
|
EP2640394A4
(en)
|
2010-11-17 |
2015-02-25 |
Univ North Carolina |
PROTECTION OF KIDNEY TISSUE FROM ISCHEMIA BY THE INHIBITION OF PROLEVERATIVE KINASES CDK4 AND CDK6
|
|
AU2014259534B2
(en)
*
|
2011-01-04 |
2016-05-19 |
Novartis Ag |
Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD)
|
|
MX347391B
(es)
*
|
2011-01-04 |
2017-04-25 |
Novartis Ag |
Compuestos de indol o análogos de los mismos útiles para el tratamiento de degeneración macular relacionada con la edad (amd).
|
|
BR112013033836A2
(pt)
*
|
2011-07-01 |
2017-02-21 |
Novartis Ag |
terapia de combinação
|
|
AU2012279117A1
(en)
*
|
2011-07-01 |
2014-01-09 |
Novartis Ag |
Combination therapy comprising a CDK4/6 inhibitor and a PI3K inhibitor for use in the treatment of cancer
|
|
US9498471B2
(en)
|
2011-10-20 |
2016-11-22 |
The Regents Of The University Of California |
Use of CDK9 inhibitors to reduce cartilage degradation
|
|
US9194840B2
(en)
|
2012-01-19 |
2015-11-24 |
Life Technologies Corporation |
Sensor arrays and methods for making same
|
|
CA2868966C
(en)
|
2012-03-29 |
2021-01-26 |
Francis Xavier Tavares |
Lactam kinase inhibitors
|
|
US10202392B2
(en)
|
2012-04-26 |
2019-02-12 |
Francis Xavier Tavares |
Synthesis of lactams
|
|
CN104379579B
(zh)
|
2012-06-28 |
2017-03-08 |
诺华股份有限公司 |
吡咯烷衍生物及其作为补体途径调节剂的用途
|
|
CN104619698B
(zh)
|
2012-06-28 |
2016-08-31 |
诺华股份有限公司 |
吡咯烷衍生物及其作为补体途径调节剂的用途
|
|
US9815819B2
(en)
|
2012-06-28 |
2017-11-14 |
Novartis Ag |
Complement pathway modulators and uses thereof
|
|
ES2712190T3
(es)
|
2012-06-28 |
2019-05-09 |
Novartis Ag |
Moduladores de la vía del complemento y sus usos
|
|
ES2644700T3
(es)
|
2012-06-28 |
2017-11-30 |
Novartis Ag |
Derivados de pirrolidina y su uso como moduladores de la ruta del complemento
|
|
JP6238980B2
(ja)
|
2012-07-12 |
2017-11-29 |
ノバルティス アーゲー |
補体経路モジュレーターおよびその使用
|
|
AR091876A1
(es)
|
2012-07-26 |
2015-03-04 |
Novartis Ag |
Combinaciones farmaceuticas para el tratamiento de enfermedades proliferativas
|
|
WO2014022830A2
(en)
|
2012-08-03 |
2014-02-06 |
Foundation Medicine, Inc. |
Human papilloma virus as predictor of cancer prognosis
|
|
EP3251673A1
(en)
|
2012-12-13 |
2017-12-06 |
IP Gesellschaft für Management mbH |
Combination therapy comprising a cdk4/6 inhibitor and a pi3k inhibitor for use in the treatment of cancer
|
|
ES2676177T3
(es)
|
2012-12-20 |
2018-07-17 |
Novartis Ag |
Una combinación farmacéutica que comprende binimetinib
|
|
US20150353542A1
(en)
|
2013-01-14 |
2015-12-10 |
Amgen Inc. |
Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
|
|
EP3327144B1
(en)
|
2013-02-25 |
2020-03-25 |
Novartis AG |
Novel androgen receptor mutation
|
|
CA2901929A1
(en)
|
2013-03-13 |
2014-10-02 |
Abbvie Inc. |
Cdk9 kinase inhibitors
|
|
BR112015021549A2
(pt)
|
2013-03-13 |
2017-07-18 |
Abbvie Inc |
inibidores de piridina cinase cdk9
|
|
AU2014234077A1
(en)
|
2013-03-14 |
2015-10-01 |
Abbvie Inc. |
Pyrrolo[2,3-b]pyridine CDK9 kinase inhibitors
|
|
TW201444836A
(zh)
|
2013-03-14 |
2014-12-01 |
Abbvie Inc |
吡咯并［２，３－ｂ］吡啶ｃｄｋ９激酶抑制劑
|
|
JP2016512560A
(ja)
*
|
2013-03-14 |
2016-04-28 |
アッヴィ・インコーポレイテッド |
ピロロピリミジン系ｃｄｋ９キナーゼ阻害薬
|
|
EP2967050A4
(en)
|
2013-03-15 |
2016-09-28 |
G1 Therapeutics Inc |
HIGH-ACTIVE ANTINEOPLASTIC AND ANTIPROLIFERATIVE AGENTS
|
|
WO2014144596A2
(en)
*
|
2013-03-15 |
2014-09-18 |
G1 Therapeutics, Inc. |
Transient protection of hematopoietic stem and progenitor cells against ionizing radiation
|
|
HRP20192168T1
(hr)
|
2013-03-15 |
2020-02-21 |
G1 Therapeutics, Inc. |
Privremena zaštita normalnih stanica tijekom kemoterapije
|
|
UA118846C2
(uk)
|
2013-03-21 |
2019-03-25 |
Новартіс Аг |
Комбінована терапія
|
|
WO2014172479A1
(en)
|
2013-04-16 |
2014-10-23 |
Memorial Sloan-Kettering Cancer Center |
Companion diagnostic for cdk4 inhibitors
|
|
CA2918190C
(en)
*
|
2013-08-14 |
2023-01-17 |
Novartis Ag |
Combination therapy comprising a cdk4/6 inhibitor and an aromatase inhibitor or fulvestrant for the treatment of cancer
|
|
MX2016002580A
(es)
*
|
2013-08-28 |
2016-10-26 |
Novartis Ag |
Combinacion de un inhibidor de alk y un inhibidor de cdk para el tratamiento de enfermedades celulares proliferativas.
|
|
US10570204B2
(en)
|
2013-09-26 |
2020-02-25 |
The Medical College Of Wisconsin, Inc. |
Methods for treating hematologic cancers
|
|
TW201605857A
(zh)
*
|
2013-10-03 |
2016-02-16 |
赫孚孟拉羅股份公司 |
Ｃｄｋ８之醫療性抑制劑及其用途
|
|
WO2015061407A1
(en)
*
|
2013-10-24 |
2015-04-30 |
Francis Xavier Tavares |
Process for synthesis of lactams
|
|
US20160375024A1
(en)
|
2013-11-27 |
2016-12-29 |
Novartis Ag |
Combination therapy comprising an inhibitor of jak, cdk, and pim
|
|
US9476853B2
(en)
|
2013-12-10 |
2016-10-25 |
Life Technologies Corporation |
System and method for forming microwells
|
|
EP3082423B1
(en)
*
|
2013-12-20 |
2024-12-11 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of cdk and erk inhibitors
|
|
CN105848656B
(zh)
|
2013-12-23 |
2019-10-25 |
诺华股份有限公司 |
药物组合
|
|
WO2015097621A2
(en)
*
|
2013-12-23 |
2015-07-02 |
Novartis Ag |
Pharmaceutical combinations
|
|
US9949976B2
(en)
|
2013-12-31 |
2018-04-24 |
Xuanzhu Pharma Co., Ltd. |
Kinase inhibitor and use thereof
|
|
RU2670762C2
(ru)
*
|
2013-12-31 |
2018-10-25 |
Хуаньчжу Фарма Ко., Лтд. |
Производные 6-(пиримидиноаминопиридин)бензоимидазола, полезные для лечения рака
|
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
|
HRP20192346T1
(hr)
|
2014-03-14 |
2020-03-20 |
Novartis Ag |
Molekule anti-lag-3 antitijela i njihove uporabe
|
|
MX385778B
(es)
|
2014-04-04 |
2025-03-18 |
Del Mar Pharmaceuticals |
Uso de dianhidrogalactitol y análogos o derivados del mismo para tratar cáncer de células no pequeñas del pulmón y cáncer de ovario.
|
|
US20150320754A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
US9717735B2
(en)
|
2014-04-17 |
2017-08-01 |
G1 Therapeutics, Inc. |
Tricyclic lactams for use in HSPC-sparing treatments for RB-positive abnormal cellular proliferation
|
|
BR112016027679B1
(pt)
*
|
2014-05-28 |
2022-10-25 |
Chongqing Fochon Pharmaceutical Co., Ltd |
Inibidores de proteína quinase, seu usos e seus métodos de fabricação, kit e composição farmacêutica
|
|
CN105294737B
(zh)
*
|
2014-07-26 |
2019-02-12 |
广东东阳光药业有限公司 |
Cdk类小分子抑制剂的化合物及其用途
|
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
|
EP3191098A4
(en)
|
2014-09-12 |
2018-04-25 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
|
WO2016040880A1
(en)
|
2014-09-13 |
2016-03-17 |
Novartis Ag |
Combination therapies of alk inhibitors
|
|
JP2017535528A
(ja)
|
2014-10-03 |
2017-11-30 |
ノバルティス アーゲー |
組み合わせ治療
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
WO2016061144A1
(en)
|
2014-10-14 |
2016-04-21 |
The Regents Of The University Of California |
Use of cdk9 and brd4 inhibitors to inhibit inflammation
|
|
CN114920840A
(zh)
|
2014-10-14 |
2022-08-19 |
诺华股份有限公司 |
针对pd-l1的抗体分子及其用途
|
|
PL3218005T3
(pl)
|
2014-11-12 |
2023-05-02 |
Seagen Inc. |
Związki oddziałujące z glikanami i sposoby ich zastosowania
|
|
US10138250B2
(en)
|
2014-12-12 |
2018-11-27 |
Crystal Pharmatech Co., Ltd. |
Salt of pyrrolo[2,3-D]pyrimidine compound and novel polymorph of salt
|
|
CN105111215B
(zh)
*
|
2014-12-12 |
2019-06-18 |
苏州晶云药物科技股份有限公司 |
一种周期蛋白依赖性激酶抑制剂的晶型及其制备方法
|
|
EP3231805B1
(en)
*
|
2014-12-12 |
2020-03-04 |
Crystal Pharmatech Co. Ltd. |
Salt of pyrrolo[2,3-d]pyrimidine compound and novel polymorph of salt
|
|
WO2016126889A1
(en)
*
|
2015-02-03 |
2016-08-11 |
G1 Therapeutics, Inc. |
Cdk4/6 inhibitor dosage formulations for the protection of hematopoietic stem and progenitor cells during chemotherapy
|
|
MY190404A
(en)
|
2015-03-10 |
2022-04-21 |
Aduro Biotech Inc |
Compositions and methods for activating "stimulator of interferon gene"-dependent signalling
|
|
WO2016151501A1
(en)
|
2015-03-25 |
2016-09-29 |
Novartis Ag |
Pharmaceutical combinations
|
|
WO2016166703A1
(en)
|
2015-04-16 |
2016-10-20 |
Novartis Ag |
Ribociclib tablet
|
|
CN106146515B
(zh)
*
|
2015-04-17 |
2020-09-04 |
常州隆赛医药科技有限公司 |
新型激酶抑制剂的制备及应用
|
|
TWI696617B
(zh)
|
2015-04-28 |
2020-06-21 |
大陸商上海復尚慧創醫藥研究有限公司 |
特定蛋白質激酶抑制劑
|
|
HUE056996T2
(hu)
|
2015-05-29 |
2022-04-28 |
Teijin Pharma Ltd |
Pirido[3,4-d]pirimidin származék és gyógyszerészetileg elfogadható sója
|
|
CN105037236B
(zh)
*
|
2015-06-04 |
2017-07-28 |
苏州明锐医药科技有限公司 |
瑞博西尼中间体及其制备方法
|
|
CN106336412A
(zh)
*
|
2015-07-10 |
2017-01-18 |
南开大学 |
作为cdk4/6抑制剂的2-(n-氧化芳环-2基氨基)-吡咯并嘧啶及嘌呤类化合物
|
|
CN106699785A
(zh)
*
|
2015-07-13 |
2017-05-24 |
南开大学 |
作为CDK4/6抑制剂的2-(N-氧化吡啶-2基氨基)-吡啶并[2,3-d]嘧啶-7-酮类化合物
|
|
CN105130992B
(zh)
*
|
2015-07-16 |
2018-02-09 |
苏州大学 |
具有激酶抑制活性的含氮杂环化合物、制备方法和用途
|
|
US20180222982A1
(en)
|
2015-07-29 |
2018-08-09 |
Novartis Ag |
Combination therapies comprising antibody molecules to pd-1
|
|
EP3316902A1
(en)
|
2015-07-29 |
2018-05-09 |
Novartis AG |
Combination therapies comprising antibody molecules to tim-3
|
|
HUE055469T2
(hu)
|
2015-07-29 |
2021-11-29 |
Novartis Ag |
A LAG-3 elleni antitest molekulákat tartalmazó kombinált terápiák
|
|
US20180250302A1
(en)
|
2015-08-28 |
2018-09-06 |
Giordano Caponigro |
Combination of ribociclib and dabrafenib for treating or preventing cancer
|
|
JP2018526377A
(ja)
|
2015-08-28 |
2018-09-13 |
ノバルティス アーゲー |
がんを治療するための、任意にｐｉ３ｋ阻害剤のｂｙｌ７１９を更に含む、ｃｄｋ４／６阻害剤のｌｅｅ０１１とｍｅｋ１／２阻害剤トラメチニブの組み合わせ物
|
|
CN108348514A
(zh)
|
2015-08-28 |
2018-07-31 |
诺华股份有限公司 |
含pi3k抑制剂alpelisib和cdk4/6抑制剂ribociclib的药物组合以及其在治疗/预防癌症中的应用
|
|
JP2018526376A
(ja)
|
2015-08-28 |
2018-09-13 |
ノバルティス アーゲー |
がんの治療または予防のための（ａ）サイクリン依存性キナーゼ４／６（ｃｄｋ４／６）阻害剤のｌｅｅ０１１（＝リボシクリブ）および（ｂ）上皮成長因子受容体（ｅｇｆｒ）阻害剤のエルロチニブを含む医薬組み合わせ物
|
|
EP3156406A1
(en)
|
2015-10-14 |
2017-04-19 |
ratiopharm GmbH |
Crystalline forms of ribociclib free base
|
|
CA3002954A1
(en)
|
2015-11-02 |
2017-05-11 |
Novartis Ag |
Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
|
|
AU2016348391A1
(en)
|
2015-11-03 |
2018-05-17 |
Janssen Biotech, Inc. |
Antibodies specifically binding TIM-3 and their uses
|
|
HK1253049A1
(zh)
|
2015-11-12 |
2019-06-06 |
Seagen Inc. |
糖基相互作用化合物及其使用方法
|
|
CN106749259B
(zh)
*
|
2015-11-19 |
2019-02-01 |
华东师范大学 |
一种环戊基嘧啶并吡咯类化合物的合成方法
|
|
CN106831780A
(zh)
*
|
2015-12-03 |
2017-06-13 |
南开大学 |
具有cdk4/6和hdac抑制活性的新型杂环衍生物
|
|
JP2019503349A
(ja)
|
2015-12-17 |
2019-02-07 |
ノバルティス アーゲー |
Ｐｄ−１に対する抗体分子およびその使用
|
|
CN105541863B
(zh)
*
|
2016-02-16 |
2017-09-05 |
安纳康科学股份有限公司 |
噻吩[2,3‑c]吡啶衍生物及其作为CDK激酶抑制剂的用途
|
|
WO2017156263A1
(en)
|
2016-03-09 |
2017-09-14 |
Memorial Sloan-Kettering Cancer Center |
Enigma and cdh18 as companion diagnostics for cdk4 inhibitors
|
|
US11077110B2
(en)
|
2016-03-18 |
2021-08-03 |
Tufts Medical Center |
Compositions and methods for treating and preventing metabolic disorders
|
|
US10570141B2
(en)
|
2016-03-25 |
2020-02-25 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Substituted pyrrolopyrimidine CDK inhibitor, pharmaceutical composition containing same and use thereof
|
|
CN107266451B
(zh)
*
|
2016-04-07 |
2021-12-31 |
上海医药工业研究院 |
瑞布昔利布中间体的制备方法
|
|
US10865204B2
(en)
|
2016-04-22 |
2020-12-15 |
Dana-Farber Cancer Institute, Inc. |
Degradation of cyclin-dependent kinase 4/6 (CDK4/6) by conjugation of CDK4/6 inhibitors with E3 ligase ligand and methods of use
|
|
WO2017193872A1
(en)
|
2016-05-07 |
2017-11-16 |
Shanghai Fochon Pharmaceutical Co., Ltd. |
Certain protein kinase inhibitors
|
|
CN108290899B
(zh)
*
|
2016-06-06 |
2020-09-18 |
深圳市塔吉瑞生物医药有限公司 |
一种取代的吡咯并嘧啶化合物及其应用
|
|
ES2908801T3
(es)
|
2016-06-07 |
2022-05-04 |
Jacobio Pharmaceuticals Co Ltd |
Nuevos derivados heterocíclicos útiles como inhibidores de SHP2
|
|
WO2018005863A1
(en)
|
2016-07-01 |
2018-01-04 |
G1 Therapeutics, Inc. |
Pyrimidine-based compounds for the treatment of cancer
|
|
WO2018005865A1
(en)
|
2016-07-01 |
2018-01-04 |
G1 Therapeutics, Inc. |
Synthesis of n-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines
|
|
WO2018005533A1
(en)
|
2016-07-01 |
2018-01-04 |
G1 Therapeutics, Inc. |
Antiproliferative pyrimidine-based compounds
|
|
CN109789143A
(zh)
*
|
2016-07-01 |
2019-05-21 |
G1治疗公司 |
基于嘧啶的抗增殖剂
|
|
WO2018009466A1
(en)
|
2016-07-05 |
2018-01-11 |
Aduro Biotech, Inc. |
Locked nucleic acid cyclic dinucleotide compounds and uses thereof
|
|
CN109803684B
(zh)
|
2016-08-23 |
2022-08-23 |
卫材 R&D 管理有限公司 |
用于治疗肝细胞癌的组合疗法
|
|
WO2018051280A1
(en)
*
|
2016-09-15 |
2018-03-22 |
Dr. Reddy’S Laboratories Limited |
Process for preparation of ribociclib, its acid addition salts
|
|
ES2974991T3
(es)
|
2016-09-19 |
2024-07-02 |
Novartis Ag |
Combinaciones terapéuticas que comprenden un inhibidor de RAF y un inhibidor de ERK
|
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
|
AU2017345367A1
(en)
|
2016-10-20 |
2019-04-04 |
Pfizer Inc. |
Anti-proliferative agents for treating PAH
|
|
WO2018081211A1
(en)
*
|
2016-10-26 |
2018-05-03 |
Li George Y |
Deuterated 7-cyclopentyl-n, n-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7h-pyrrolo[2,3-d]pyrimdine-6-carboxamide
|
|
AU2017359333B2
(en)
|
2016-11-08 |
2024-03-21 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of modulating anti-tumor immunity
|
|
US11401330B2
(en)
|
2016-11-17 |
2022-08-02 |
Seagen Inc. |
Glycan-interacting compounds and methods of use
|
|
EP3541391A4
(en)
|
2016-11-17 |
2020-06-17 |
The University of North Carolina at Chapel Hill |
ALKYL PYRROLOPYRIMIDINE ANALOGS AND METHODS OF PREPARING AND USING THE SAME
|
|
SI3546456T1
(sl)
|
2016-11-28 |
2022-04-29 |
Teijin Pharma Limited |
Kristal derivata pirido(3,4-D)pirimidina ali njegovega solvata
|
|
DK3546458T3
(da)
|
2016-11-28 |
2021-02-22 |
Teijin Pharma Ltd |
((pyridin-2-yl)-amino)pyrido[3,4-d]pyrimidin- og ((pyridazin-3-yl)-amino)pyrido[3,4-d]pyrimidinderivater som cdk4/6-inhibitorer til behandling af for eksempel rheumatoid artritis, arteriosklerose, lungefibrose, cerebral infarkt eller kræft
|
|
IL303038B2
(en)
|
2016-12-05 |
2024-08-01 |
G1 Therapeutics Inc |
Preservation of immune response during chemotherapy regimens
|
|
WO2018129387A1
(en)
|
2017-01-06 |
2018-07-12 |
G1 Therapeutics, Inc. |
Combination therapy for the treatment of cancer
|
|
EP3573619A4
(en)
*
|
2017-01-27 |
2020-10-28 |
SignalRX Pharmaceuticals, Inc. |
THIENOPYRANONES AND FURANOPYRANONES AS KINASE, BROMODOMAIN AND CHECKPOINT INHIBITORS
|
|
US11395821B2
(en)
|
2017-01-30 |
2022-07-26 |
G1 Therapeutics, Inc. |
Treatment of EGFR-driven cancer with fewer side effects
|
|
KR102653141B1
(ko)
|
2017-03-03 |
2024-04-01 |
씨젠 인크. |
글리칸-상호작용 화합물 및 사용 방법
|
|
SG11201908531WA
(en)
|
2017-03-16 |
2019-10-30 |
Eisai R&D Man Co Ltd |
Combination therapies for the treatment of breast cancer
|
|
HRP20241239T1
(hr)
|
2017-03-23 |
2024-12-06 |
Jacobio Pharmaceuticals Co., Ltd. |
Novi heterociklički derivati korisni kao shp2 inhibitori
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
IL270224B1
(en)
|
2017-05-02 |
2024-04-01 |
Novartis Ag |
Combination therapy employing trametinib and a defined raf inhibitor
|
|
CN107118215B
(zh)
*
|
2017-05-06 |
2019-04-05 |
上海耀大生物科技有限公司 |
一种治疗乳腺癌药物瑞博西尼中间体的制备方法
|
|
CN106946880B
(zh)
*
|
2017-05-06 |
2019-04-26 |
南京焕然生物科技有限公司 |
一种制备瑞博西尼中间体的方法
|
|
CN107267481A
(zh)
*
|
2017-05-09 |
2017-10-20 |
上海交通大学医学院附属新华医院 |
Cdk5抗原表位肽及其应用
|
|
CN108929324A
(zh)
*
|
2017-05-22 |
2018-12-04 |
南开大学 |
新型1,1-环丙基二酰胺衍生物的制备与应用
|
|
CN108929312A
(zh)
*
|
2017-05-22 |
2018-12-04 |
南开大学 |
具有cdk或hdac抑制活性的新型苯并杂环联嘧啶抑制剂
|
|
TW201906818A
(zh)
*
|
2017-05-31 |
2019-02-16 |
美商５１１製藥公司 |
新穎氘取代之正子發射斷層掃描（ｐｅｔ）顯影劑及其藥理應用
|
|
WO2018218633A1
(en)
|
2017-06-02 |
2018-12-06 |
Beijing Percans Oncology Co. Ltd. |
Combination therapies for treating cancers
|
|
WO2018237173A1
(en)
|
2017-06-22 |
2018-12-27 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
IL315143A
(en)
|
2017-06-29 |
2024-10-01 |
G1 Therapeutics Inc |
Morphic forms of g1t38 and methods of manufacture thereof
|
|
CA3069561A1
(en)
|
2017-08-03 |
2019-02-07 |
Novartis Ag |
Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitor
|
|
EP4327880A3
(en)
|
2017-08-25 |
2024-05-22 |
Assia Chemical Industries Ltd. |
Solid state form of ribociclib succinate
|
|
CN119162314A
(zh)
|
2017-08-31 |
2024-12-20 |
诺华股份有限公司 |
选择针对癌症患者的治疗的方法
|
|
US11286259B2
(en)
|
2017-09-29 |
2022-03-29 |
Hangzhou Solipharma Co., Ltd. |
Co-crystals of ribociclib and co-crystals of ribociclib monosuccinate, preparation method therefor, compositions thereof, and uses thereof
|
|
WO2019082143A1
(en)
|
2017-10-27 |
2019-05-02 |
Fresenius Kabi Oncology Ltd. |
IMPROVED PROCESS FOR THE PREPARATION OF RIBOCICLIB AND ITS SALTS
|
|
US11179365B2
(en)
|
2017-11-16 |
2021-11-23 |
Novartis Ag |
Pharmaceutical combination comprising LSZ102 and ribociclib
|
|
US20200277378A1
(en)
|
2017-11-16 |
2020-09-03 |
Novartis Ag |
Combination therapies
|
|
BR112020012635A2
(pt)
*
|
2017-12-22 |
2020-12-01 |
Ravenna Pharmaceuticals, Inc. |
derivados de aminopiridina como inibidores de fosfatidilinositol fosfato quinase
|
|
WO2019123364A1
(en)
|
2017-12-22 |
2019-06-27 |
Shilpa Medicare Limited |
Novel polymorphs of ribociclib mono succinate
|
|
WO2019133864A1
(en)
|
2017-12-29 |
2019-07-04 |
Accutar Biotechnology |
DUAL INHIBITORS OF PARP1 and CDK
|
|
JP2021509680A
(ja)
|
2018-01-08 |
2021-04-01 |
ジー１、セラピューティクス、インコーポレイテッドＧ１ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． |
Ｇ１ｔ３８の優れた投与レジメン
|
|
CN107936029B
(zh)
*
|
2018-01-08 |
2020-06-30 |
南京奇可药业有限公司 |
一种合成瑞博西尼的方法
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
CA3088381A1
(en)
*
|
2018-01-29 |
2019-08-01 |
Beta Pharma, Inc. |
2h-indazole derivatives as cdk4 and cdk6 inhibitors and therapeutic uses thereof
|
|
WO2019161224A1
(en)
|
2018-02-15 |
2019-08-22 |
GiraFpharma LLC |
Heterocyclic compounds as kinase inhibitors
|
|
WO2019167068A1
(en)
|
2018-03-01 |
2019-09-06 |
Cipla Limited |
Novel polymorphs of ribociclib succinate
|
|
WO2019195959A1
(en)
|
2018-04-08 |
2019-10-17 |
Cothera Biosciences, Inc. |
Combination therapy for cancers with braf mutation
|
|
US10723739B2
(en)
|
2018-05-14 |
2020-07-28 |
Apotex Inc. |
Processes for the preparation of Ribociclib and intermediates thereof
|
|
WO2019222521A1
(en)
*
|
2018-05-16 |
2019-11-21 |
G1 Therapeutics, Inc. |
Cdk inhibitors for the treatment of neoplastic disorders
|
|
CN108558745A
(zh)
*
|
2018-05-17 |
2018-09-21 |
苏州莱克施德药业有限公司 |
一种帕博西林中间体的合成方法
|
|
TWI869346B
(zh)
|
2018-05-30 |
2025-01-11 |
瑞士商諾華公司 |
Ｅｎｔｐｄ２抗體、組合療法、及使用該等抗體和組合療法之方法
|
|
MA52806A
(fr)
|
2018-06-05 |
2021-04-14 |
Crinetics Pharmaceuticals Inc |
Antagonistes du récepteur de la mélanocortine de sous-type 2 (mc2r) et leurs utilisations
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
CN112703186A
(zh)
|
2018-07-27 |
2021-04-23 |
加利福尼亚技术学院 |
Cdk抑制剂及其用途
|
|
KR20210044251A
(ko)
|
2018-08-13 |
2021-04-22 |
베이징 페르칸스 온콜로지 컴퍼니 리미티드 |
암 치료용 바이오마커
|
|
EP3840756B1
(en)
|
2018-08-24 |
2025-11-05 |
Pharmacosmos Holding A/S |
Improved synthesis of 1,4-diazaspiro[5.5]undecan-3-one
|
|
JP2022500458A
(ja)
*
|
2018-09-13 |
2022-01-04 |
チア タイ ティエンチン ファーマシューティカル グループ カンパニー リミテッドChia Tai Tianqing Pharmaceutical Group Co., Ltd. |
置換ピロロピリミジン系ｃｄｋ阻害剤の塩とその結晶および使用
|
|
WO2020063760A1
(en)
|
2018-09-26 |
2020-04-02 |
Jacobio Pharmaceuticals Co., Ltd. |
Novel heterocyclic derivatives useful as shp2 inhibitors
|
|
WO2020084389A1
(en)
|
2018-10-23 |
2020-04-30 |
Lupin Limited |
Ribociclib intermediate and process for preparation thereof
|
|
FI3873903T3
(fi)
|
2018-10-31 |
2024-03-26 |
Gilead Sciences Inc |
Substituoituja 6-azabentsiimidatsoliyhdisteitä HPK1-inhibiittoreina
|
|
KR102658602B1
(ko)
|
2018-10-31 |
2024-04-19 |
길리애드 사이언시즈, 인코포레이티드 |
Hpk1 억제 활성을 갖는 치환된 6-아자벤즈이미다졸 화합물
|
|
CN113271945A
(zh)
|
2018-12-20 |
2021-08-17 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案和药物组合
|
|
CN109400612A
(zh)
*
|
2018-12-24 |
2019-03-01 |
重庆三圣实业股份有限公司 |
一种瑞博西尼的制备方法及其产品和用途
|
|
WO2020140054A1
(en)
|
2018-12-28 |
2020-07-02 |
Spv Therapeutics Inc. |
Cyclin-dependent kinase inhibitors
|
|
WO2020140052A1
(en)
*
|
2018-12-28 |
2020-07-02 |
Spv Therapeutics Inc. |
Cyclin-dependent kinase inhibitors
|
|
KR20210119444A
(ko)
|
2019-01-23 |
2021-10-05 |
노파르티스 아게 |
7-사이클로펜틸-2-(5-피페라진-1-일-피리딘-2-일아미노)-7h-피롤로[2,3-d]피리미딘-6-카복실산 디메틸아미드의 석신산염의 신규한 결정질 형태
|
|
BR112021015632A2
(pt)
|
2019-02-12 |
2021-10-05 |
Novartis Ag |
Combinação farmacêutica que compreende tno155 e ribociclibe
|
|
EP3924055B1
(en)
|
2019-02-15 |
2024-04-03 |
Novartis AG |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN113490528B
(zh)
|
2019-02-15 |
2024-12-03 |
诺华股份有限公司 |
3-(1-氧代-5-(哌啶-4-基)异吲哚啉-2-基)哌啶-2,6-二酮衍生物及其用途
|
|
IL315588A
(en)
|
2019-05-05 |
2024-11-01 |
Regor Pharmaceuticals Inc |
CDK inhibitors
|
|
WO2020225827A1
(en)
|
2019-05-08 |
2020-11-12 |
Mylan Laboratories Limited |
Novel polymorphs of ribociclib succinate
|
|
AU2020276695B2
(en)
|
2019-05-13 |
2025-12-18 |
Novartis Ag |
New crystalline forms of N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methvlphenyl)-2 (trifluoromethyl)isonicotinamide as RAF inhibitors for the treatment of cancer
|
|
SG11202112056PA
(en)
|
2019-05-20 |
2021-12-30 |
Novartis Ag |
Mcl-1 inhibitor antibody-drug conjugates and methods of use
|
|
WO2020237025A1
(en)
|
2019-05-23 |
2020-11-26 |
Gilead Sciences, Inc. |
Substituted exo-methylene-oxindoles which are hpk1/map4k1 inhibitors
|
|
DK3980411T3
(da)
*
|
2019-06-04 |
2025-10-13 |
Step Pharma S A S |
N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(ethylsulfonamido)pyrimidin-4-yl)tetrahydro-2h-pyran-4-carboxamid som en human ctps1-inhibitor til behandling af proliferative sygdomme
|
|
TW202112767A
(zh)
|
2019-06-17 |
2021-04-01 |
美商佩特拉製藥公司 |
作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物
|
|
CN112094272A
(zh)
|
2019-06-18 |
2020-12-18 |
北京睿熙生物科技有限公司 |
Cdk激酶抑制剂
|
|
BR112022003490A2
(pt)
|
2019-08-26 |
2022-05-24 |
Arvinas Operations Inc |
Método de tratamento do câncer de mama e mama metastático, método para degradação seletiva, método para inibir uma quinase, kit, composição líquida, e, método de produção de uma composição líquida
|
|
WO2021038590A1
(en)
|
2019-08-30 |
2021-03-04 |
Mylan Laboratories Limited |
Novel polymorph of ribociclib succinate
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Ｅｎｔｐｄ２抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
WO2021091788A1
(en)
*
|
2019-11-07 |
2021-05-14 |
Crinetics Pharmaceuticals, Inc. |
Melanocortin subtype-2 receptor (mc2r) antagonists and uses thereof
|
|
WO2021124106A1
(en)
*
|
2019-12-16 |
2021-06-24 |
Lunella Biotech, Inc. |
Selective cdk4/6 inhibitor cancer therapeutics
|
|
MX2022007488A
(es)
|
2019-12-16 |
2022-08-02 |
Lunella Biotech Inc |
Agentes terapeuticos selectivos contra el cancer inhibidores de cdk4/6.
|
|
MD4077307T2
(ro)
|
2019-12-18 |
2025-09-30 |
Crinetics Pharmaceuticals Inc |
Antagoniști ai receptorilor de melanocortină subtip-2 (MC2R) piperidină gem-disubstituiţi și utilizări ale acestora
|
|
CN115175937A
(zh)
|
2019-12-20 |
2022-10-11 |
诺华股份有限公司 |
用于治疗骨髓纤维化和骨髓增生异常综合征的抗TIM-3抗体MBG453和抗TGF-β抗体NIS793与或不与地西他滨或抗PD-1抗体斯巴达珠单抗的组合
|
|
CA3161892A1
(en)
|
2019-12-23 |
2021-07-01 |
Jie Fan |
Combinations of estrogen receptor degraders and cyclin-dependent kinase inhibitors for treating cancer
|
|
EP4081525B1
(en)
|
2019-12-23 |
2025-05-21 |
Crinetics Pharmaceuticals, Inc. |
Spirocyclic piperidine melanocortin subtype-2 receptor (mc2r) antagonists and uses thereof
|
|
EP4126244A4
(en)
*
|
2020-03-27 |
2024-03-27 |
Jiangsu Alphamab Biopharmaceuticals Co., Ltd. |
COMBINATION OF ANTI-HER2 ANTIBODIES AND CDK INHIBITORS FOR TUMOR TREATMENT
|
|
EP4140997A4
(en)
*
|
2020-05-12 |
2023-09-06 |
Suzhou Alphama Biotechnology Co., Ltd. |
PYRIDINE ACETAMIDE DERIVATIVE AS CDK INHIBITOR, PREPARATION METHOD AND USE THEREOF
|
|
CN113149996B
(zh)
*
|
2020-05-12 |
2022-12-20 |
苏州阿尔脉生物科技有限公司 |
一种作为cdk9抑制剂的多环酰胺类衍生物、其制备方法及用途
|
|
WO2021229439A1
(en)
|
2020-05-12 |
2021-11-18 |
Novartis Ag |
Therapeutic combinations comprising a craf inhibitor
|
|
WO2021236650A1
(en)
|
2020-05-19 |
2021-11-25 |
G1 Therapeutics, Inc. |
Cyclin-dependent kinase inhibiting compounds for the treatment of medical disorders
|
|
US11964983B2
(en)
*
|
2020-06-11 |
2024-04-23 |
Lunella Biotech, Inc. |
Selective CDK4/6 inhibitor cancer therapeutics
|
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|
|
CN115916199A
(zh)
|
2020-06-23 |
2023-04-04 |
诺华股份有限公司 |
包含3-(1-氧代异吲哚啉-2-基)哌啶-2,6-二酮衍生物的给药方案
|
|
WO2022029573A1
(en)
|
2020-08-03 |
2022-02-10 |
Novartis Ag |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN112375081B
(zh)
*
|
2020-11-23 |
2022-04-12 |
中国医学科学院医药生物技术研究所 |
具有抑制CDK4、6或9活性的吡咯[2,3-d]嘧啶衍生物及其制备方法和应用
|
|
EP4251208A1
(en)
|
2020-11-24 |
2023-10-04 |
Novartis AG |
Mcl-1 inhibitor antibody-drug conjugates and methods of use
|
|
CN116615252A
(zh)
|
2020-11-24 |
2023-08-18 |
诺华股份有限公司 |
抗cd48抗体、抗体药物缀合物及其用途
|
|
WO2022162122A1
(en)
|
2021-01-29 |
2022-08-04 |
Biotx.Ai Gmbh |
Genetically verified netosis inhibitor for use in the treatment of a sars-cov2 infection
|
|
US20240376094A2
(en)
|
2021-02-02 |
2024-11-14 |
Les Laboratoires Servier |
Selective bcl-xl protac compounds and methods of use
|
|
AU2022240609A1
(en)
|
2021-03-19 |
2023-09-28 |
Crinetics Pharmaceuticals, Inc. |
Melanocortin subtype-2 receptor (mc2r) antagonist for the treatment of disease
|
|
EP4313987B1
(en)
|
2021-04-01 |
2026-01-14 |
KRKA, d.d., Novo mesto |
Process for the preparation of ribociclib and pharmaceutically acceptable salts thereof
|
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗ＴＧＦβ抗體及其他治療劑用於治療增殖性疾病之用途
|
|
EP4333847A1
(en)
|
2021-05-05 |
2024-03-13 |
Novartis AG |
Compounds and compositions for the treatment of mpnst
|
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
|
AU2022311961A1
(en)
|
2021-07-16 |
2023-11-09 |
Dana-Farber Cancer Institute, Inc. |
Small molecule cyclin dependent kinase 4/6 (cdk4/6) and ikzf2 (helios) degraders and methods of use thereof
|
|
EP4376848A1
(en)
|
2021-07-26 |
2024-06-05 |
Celcuity Inc. |
1-(4-{[4-(dimethylamino)piperidin-1-yl]carbonyl}phenyl)-3-[4-(4,6-dimorpholin-4-yl-1,3,5-triazin-2-yl)phenyl]urea (gedatolisib) and its combinations for use in the treatment of cancer
|
|
KR20240041340A
(ko)
*
|
2021-07-27 |
2024-03-29 |
보로노이 주식회사 |
피롤로피리미딘 유도체 화합물 및 이의 용도
|
|
TWI848533B
(zh)
|
2022-01-25 |
2024-07-11 |
瑞士商諾華公司 |
瑞博西尼藥物組成物
|
|
CN114456180B
(zh)
*
|
2022-02-18 |
2023-07-25 |
贵州大学 |
用于治疗和/或预防恶性肿瘤的化合物及药物制剂和应用
|
|
CN119137102A
(zh)
|
2022-04-08 |
2024-12-13 |
拜奥列司治疗有限公司 |
Cdk9抑制剂
|
|
KR20250002427A
(ko)
*
|
2022-04-08 |
2025-01-07 |
바이오렉시스 테라퓨틱스, 인크. |
Cdk9 억제제
|
|
EP4525925A1
(en)
|
2022-05-20 |
2025-03-26 |
Novartis AG |
Epha2 bcl-xl inhibitor antibody-drug conjugates and methods of use thereof
|
|
TW202404645A
(zh)
|
2022-05-20 |
2024-02-01 |
瑞士商諾華公司 |
Met bcl-xl抑制劑抗體-藥物結合物及其使用方法
|
|
TWI866427B
(zh)
|
2022-08-31 |
2024-12-11 |
美商亞文納營運公司 |
雌激素受體降解劑之給藥方案
|
|
EP4605088A1
(en)
*
|
2022-10-21 |
2025-08-27 |
Novartis AG |
Molecular glue degrader compounds and uses thereof
|
|
CN120187416A
(zh)
|
2022-11-11 |
2025-06-20 |
阿斯利康(瑞典)有限公司 |
用于治疗癌症的组合疗法
|
|
EP4626890A1
(en)
|
2022-12-01 |
2025-10-08 |
KRKA, d.d., Novo mesto |
Ribociclib salts and formulations thereof
|
|
WO2024189481A1
(en)
|
2023-03-10 |
2024-09-19 |
Novartis Ag |
Panras inhibitor antibody-drug conjugates and methods of use thereof
|
|
TW202508595A
(zh)
|
2023-05-04 |
2025-03-01 |
美商銳新醫藥公司 |
用於ｒａｓ相關疾病或病症之組合療法
|
|
AU2024269592A1
(en)
|
2023-05-05 |
2025-12-18 |
Astrazeneca Ab |
Combination of capivasertib, a cdk4/6 inhibitor and fulvestrant for use in the treatment of breast cancer
|
|
WO2024235844A1
(en)
|
2023-05-12 |
2024-11-21 |
Institut National de la Santé et de la Recherche Médicale |
Methods of preventing on-target genotoxicity induced by nucleases
|
|
WO2025034702A1
(en)
|
2023-08-07 |
2025-02-13 |
Revolution Medicines, Inc. |
Rmc-6291 for use in the treatment of ras protein-related disease or disorder
|
|
CN117069663B
(zh)
*
|
2023-08-31 |
2023-12-26 |
四川维亚本苑生物科技有限公司 |
一种瑞博西尼中间体v的合成方法及瑞博西尼的合成方法
|
|
WO2025051337A1
(en)
|
2023-09-06 |
2025-03-13 |
Afyx Development A/S |
Compositions and methods for treating and preventing oral cancer
|
|
US20250114357A1
(en)
*
|
2023-10-10 |
2025-04-10 |
Biolexis Therapeutics, Inc. |
Bifunctional protac and molecular glue compounds and methods of use thereof
|
|
WO2025080946A2
(en)
|
2023-10-12 |
2025-04-17 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025111450A1
(en)
|
2023-11-22 |
2025-05-30 |
Les Laboratoires Servier |
Anti-cd74 antibody-drug conjugates and methods of use thereof
|
|
WO2025171296A1
(en)
|
2024-02-09 |
2025-08-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025217307A1
(en)
|
2024-04-09 |
2025-10-16 |
Revolution Medicines, Inc. |
Methods for predicting response to a ras(on) inhibitor and combination therapies
|
|
WO2025215536A1
(en)
|
2024-04-10 |
2025-10-16 |
Novartis Ag |
Macrocyclic panras inhibitors for the treatment of cancer
|
|
WO2025219830A1
(en)
|
2024-04-15 |
2025-10-23 |
Novartis Ag |
Pharmaceutical compositions of ribociclib
|
|
WO2025235331A1
(en)
*
|
2024-05-07 |
2025-11-13 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing pyrazolopyrimidine derivatives for degrading certain cyclin-dependent kinase via ubiquitin proteasome pathway
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
US20250375445A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2025265060A1
(en)
|
2024-06-21 |
2025-12-26 |
Revolution Medicines, Inc. |
Therapeutic compositions and methods for managing treatment-related effects
|
|
WO2026006747A1
(en)
|
2024-06-28 |
2026-01-02 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026015825A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Use of ras inhibitor for treating pancreatic cancer
|
|
WO2026015796A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015790A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015801A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
CN120441576B
(zh)
*
|
2025-07-08 |
2025-09-26 |
山东大学 |
一种靶向cdk4/6的化合物及其衍生的放射性示踪剂
|
|
CN120483984B
(zh)
*
|
2025-07-09 |
2025-10-10 |
山东大学 |
一种靶向cdk4/6的分子影像探针标记前体、探针及其制备方法与应用
|