|
AU2009284098B2
(en)
|
2008-08-22 |
2012-03-29 |
Astex Therapeutics Ltd. |
Pyrrolopyrimidine compounds as CDK inhibitors
|
|
EP3025724B1
(en)
|
2009-05-13 |
2018-07-11 |
The University of North Carolina At Chapel Hill |
Cyclin dependent kinase inhibitors and methods of use
|
|
UY33226A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina deuterada como inhibidores de la cdk4/6
|
|
UY33227A
(es)
|
2010-02-19 |
2011-09-30 |
Novartis Ag |
Compuestos de pirrolopirimidina como inhibidores de la cdk4/6
|
|
US20130035336A1
(en)
*
|
2010-04-13 |
2013-02-07 |
Novartis Ag |
Combination comprising a cyclin dependent kinase 4 or cyclin dependent kinase (cdk4/6) inhibitor for treating cancer
|
|
WO2012024500A1
(en)
|
2010-08-18 |
2012-02-23 |
Life Technologies Corporation |
Chemical coating of microwell for electrochemical detection device
|
|
US8691830B2
(en)
|
2010-10-25 |
2014-04-08 |
G1 Therapeutics, Inc. |
CDK inhibitors
|
|
KR102186969B1
(ko)
*
|
2010-10-25 |
2020-12-04 |
쥐원 쎄라퓨틱스, 인크. |
Cdk 억제제
|
|
AR083797A1
(es)
|
2010-11-10 |
2013-03-20 |
Novartis Ag |
Succinato de dimetil-amida del acido 7-ciclopentil-2-(5-piperazin-1-il-piridin-2-il-amino)-7h-pirrolo-[2,3-d]pirimidin-6-carboxilico, proceso para prepararla, intermediarios de dicha sintesis y proceso de preparacion de los mismos
|
|
WO2012068381A2
(en)
|
2010-11-17 |
2012-05-24 |
The University Of North Carolina At Chapel Hill |
Protection of renal tissues from schema through inhibition of the proliferative kisses cdk4 and cdk6
|
|
CN103402996B
(zh)
|
2011-01-04 |
2015-02-11 |
诺瓦提斯公司 |
可用于治疗年龄相关性黄斑变性(amd)的吲哚化合物或其类似物
|
|
AU2014259534B2
(en)
*
|
2011-01-04 |
2016-05-19 |
Novartis Ag |
Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD)
|
|
CA2840620A1
(en)
|
2011-07-01 |
2013-01-10 |
Novartis Ag |
Combination therapy
|
|
US9271988B2
(en)
|
2011-07-01 |
2016-03-01 |
Novartis Ag |
Combination therapy comprising a CDK4/6 inhibitor and a P13K inhibitor for use in the treatment of cancer
|
|
WO2013059634A1
(en)
|
2011-10-20 |
2013-04-25 |
The Regents Of The University Of California |
Use of cdk9 inhibitors to reduce cartilage degradation
|
|
US9194840B2
(en)
|
2012-01-19 |
2015-11-24 |
Life Technologies Corporation |
Sensor arrays and methods for making same
|
|
EP3216792B1
(en)
|
2012-03-29 |
2020-05-27 |
G1 Therapeutics, Inc. |
Lactam kinase inhibitors
|
|
CA2870019C
(en)
|
2012-04-26 |
2020-08-18 |
Francis Xavier Tavares |
Synthesis of lactams
|
|
WO2014002051A2
(en)
|
2012-06-28 |
2014-01-03 |
Novartis Ag |
Complement pathway modulators and uses thereof
|
|
JP6209605B2
(ja)
|
2012-06-28 |
2017-10-04 |
ノバルティス アーゲー |
ピロリジン誘導体、および補体経路調節因子としてのその使用
|
|
CN104640855B
(zh)
|
2012-06-28 |
2017-08-29 |
诺华股份有限公司 |
补体途经调节剂及其用途
|
|
EP2867229B1
(en)
|
2012-06-28 |
2017-07-26 |
Novartis AG |
Pyrrolidine derivatives and their use as complement pathway modulators
|
|
CN104619698B
(zh)
|
2012-06-28 |
2016-08-31 |
诺华股份有限公司 |
吡咯烷衍生物及其作为补体途径调节剂的用途
|
|
US9550755B2
(en)
|
2012-07-12 |
2017-01-24 |
Novartis Ag |
Complement pathway modulators and uses thereof
|
|
AR091876A1
(es)
|
2012-07-26 |
2015-03-04 |
Novartis Ag |
Combinaciones farmaceuticas para el tratamiento de enfermedades proliferativas
|
|
HK1213044A1
(zh)
|
2012-08-03 |
2016-06-24 |
Foundation Medicine, Inc. |
人乳头瘤病毒作为肿瘤预後的预测因子
|
|
EP2742940B1
(en)
|
2012-12-13 |
2017-07-26 |
IP Gesellschaft für Management mbH |
Fumarate salt of (R)-3-(6-(4-methylphenyl)-pyridin-3-yloxy)-l-aza-bicyclo-[2.2.2]octane for adminstration once daily, twice daily or thrice daily
|
|
EP2934515B1
(en)
|
2012-12-20 |
2018-04-04 |
Novartis AG |
A pharmaceutical combination comprising binimetinib
|
|
US20150353542A1
(en)
|
2013-01-14 |
2015-12-10 |
Amgen Inc. |
Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
|
|
EP2959013A2
(en)
|
2013-02-25 |
2015-12-30 |
Novartis AG |
Novel androgen receptor mutation
|
|
JP2016512559A
(ja)
*
|
2013-03-13 |
2016-04-28 |
アッヴィ・インコーポレイテッド |
Ｃｄｋ９キナーゼ阻害薬
|
|
TW201444820A
(zh)
|
2013-03-13 |
2014-12-01 |
Abbvie Inc |
吡啶ｃｄｋ９激酶抑制劑
|
|
TW201446763A
(zh)
|
2013-03-14 |
2014-12-16 |
Abbvie Inc |
吡咯并［２，３－ｂ］吡啶ｃｄｋ９激酶抑制劑
|
|
MX2015012899A
(es)
|
2013-03-14 |
2016-06-02 |
Abbvie Inc |
Pirrolo [2,3-b] piridina como inhibidores de quinasa cdk9.
|
|
CN105189512A
(zh)
*
|
2013-03-14 |
2015-12-23 |
艾伯维公司 |
吡咯并嘧啶cdk9激酶抑制剂
|
|
CA2906157C
(en)
|
2013-03-15 |
2022-05-17 |
G1 Therapeutics, Inc. |
Highly active anti-neoplastic and anti-proliferative agents
|
|
JP6430483B2
(ja)
|
2013-03-15 |
2018-11-28 |
ジー１、セラピューティクス、インコーポレイテッドＧ１ Ｔｈｅｒａｐｅｕｔｉｃｓ， Ｉｎｃ． |
化学療法の間の正常細胞の一時的な保護
|
|
WO2014144596A2
(en)
*
|
2013-03-15 |
2014-09-18 |
G1 Therapeutics, Inc. |
Transient protection of hematopoietic stem and progenitor cells against ionizing radiation
|
|
US9913844B2
(en)
|
2013-03-21 |
2018-03-13 |
Novartis Ag |
Combination therapy
|
|
CA2909683A1
(en)
|
2013-04-16 |
2014-10-23 |
Memorial Sloan-Kettering Cancer Center |
Companion diagnostic for cdk4 inhibitors
|
|
EP4772247A2
(en)
*
|
2013-08-14 |
2026-07-08 |
Novartis AG |
Combination therapy comprising ribociclib and fulvestrant for the treatment of cancer
|
|
US20160361314A1
(en)
*
|
2013-08-28 |
2016-12-15 |
Novartis Ag |
Combination of an alk inhibitor and a cdk inhibitor for the treatment of cell proliferative diseases
|
|
EP3049442A4
(en)
|
2013-09-26 |
2017-06-28 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
|
TW201605857A
(zh)
*
|
2013-10-03 |
2016-02-16 |
赫孚孟拉羅股份公司 |
Ｃｄｋ８之醫療性抑制劑及其用途
|
|
WO2015061407A1
(en)
*
|
2013-10-24 |
2015-04-30 |
Francis Xavier Tavares |
Process for synthesis of lactams
|
|
KR20160090814A
(ko)
|
2013-11-27 |
2016-08-01 |
노파르티스 아게 |
Jak, cdk 및 pim의 억제제를 포함하는 조합 요법
|
|
US9476853B2
(en)
|
2013-12-10 |
2016-10-25 |
Life Technologies Corporation |
System and method for forming microwells
|
|
US11013743B2
(en)
*
|
2013-12-20 |
2021-05-25 |
Biomed Valley Discoveries, Inc. |
Cancer treatments using combinations of CDK and ERK inhibitors
|
|
KR102283895B1
(ko)
|
2013-12-23 |
2021-07-30 |
노파르티스 아게 |
제약 조합물
|
|
AU2014372166B2
(en)
*
|
2013-12-23 |
2017-10-26 |
Novartis Ag |
Pharmaceutical combinations
|
|
RU2670762C2
(ru)
*
|
2013-12-31 |
2018-10-25 |
Хуаньчжу Фарма Ко., Лтд. |
Производные 6-(пиримидиноаминопиридин)бензоимидазола, полезные для лечения рака
|
|
US9949976B2
(en)
|
2013-12-31 |
2018-04-24 |
Xuanzhu Pharma Co., Ltd. |
Kinase inhibitor and use thereof
|
|
UA122479C2
(uk)
|
2014-01-24 |
2020-11-25 |
Дана-Фарбер Кенсер Інстітьют, Інк. |
Виділена молекула антитіла, яка зв’язується з людським білком програмованої смерті-1 (pd-1)
|
|
PL3099717T3
(pl)
|
2014-01-31 |
2019-10-31 |
Novartis Ag |
Cząsteczki przeciwciała dla TIM-3 i ich zastosowanie
|
|
EA201691765A1
(ru)
|
2014-03-14 |
2016-12-30 |
Новартис Аг |
Молекулы антител против lag-3 и их применения
|
|
KR102359214B1
(ko)
|
2014-04-04 |
2022-02-07 |
델 마 파마슈티컬스 |
폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체
|
|
US20150320754A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
|
WO2015161283A1
(en)
|
2014-04-17 |
2015-10-22 |
G1 Therapeutics, Inc. |
Tricyclic lactams for use in hspc-sparing treatments for rb-positive abnormal cellular proliferation
|
|
RU2671494C2
(ru)
*
|
2014-05-28 |
2018-11-01 |
Шанхай Фокон Фармасьютикал Ко., Лтд |
Некоторые ингибиторы протеинкиназы
|
|
CN105294737B
(zh)
*
|
2014-07-26 |
2019-02-12 |
广东东阳光药业有限公司 |
Cdk类小分子抑制剂的化合物及其用途
|
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
|
EP3191098A4
(en)
|
2014-09-12 |
2018-04-25 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
|
EP3191126B1
(en)
|
2014-09-13 |
2020-05-13 |
Novartis AG |
Combination therapies of alk inhibitors
|
|
KR20170066546A
(ko)
|
2014-10-03 |
2017-06-14 |
노파르티스 아게 |
조합 요법
|
|
MA41044A
(fr)
|
2014-10-08 |
2017-08-15 |
Novartis Ag |
Compositions et procédés d'utilisation pour une réponse immunitaire accrue et traitement contre le cancer
|
|
SG11201702401RA
(en)
|
2014-10-14 |
2017-04-27 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
|
US10300073B2
(en)
|
2014-10-14 |
2019-05-28 |
The Regents Of The University Of California |
Use of CDK9 and BRD4 inhibitors to inhibit inflammation
|
|
MX2017006167A
(es)
|
2014-11-12 |
2018-03-23 |
Siamab Therapeutics Inc |
Compuestos que interactúan con glicanos y métodos de uso.
|
|
WO2016091221A1
(zh)
*
|
2014-12-12 |
2016-06-16 |
苏州晶云药物科技有限公司 |
吡咯并[2,3-d]嘧啶化合物的盐及盐的新晶型
|
|
US10138250B2
(en)
|
2014-12-12 |
2018-11-27 |
Crystal Pharmatech Co., Ltd. |
Salt of pyrrolo[2,3-D]pyrimidine compound and novel polymorph of salt
|
|
CN105111215B
(zh)
*
|
2014-12-12 |
2019-06-18 |
苏州晶云药物科技股份有限公司 |
一种周期蛋白依赖性激酶抑制剂的晶型及其制备方法
|
|
US20160220569A1
(en)
*
|
2015-02-03 |
2016-08-04 |
G1 Therapeutics, Inc. |
CDK4/6 Inhibitor Dosage Formulations For The Protection Of Hematopoietic Stem And Progenitor Cells During Chemotherapy
|
|
TWI706958B
(zh)
|
2015-03-10 |
2020-10-11 |
美商艾杜諾生物科技公司 |
活化「干擾素基因刺激因子」依賴性訊息傳導之組合物及方法
|
|
WO2016151501A1
(en)
|
2015-03-25 |
2016-09-29 |
Novartis Ag |
Pharmaceutical combinations
|
|
SI4197530T1
(sl)
|
2015-04-16 |
2026-03-31 |
Novartis Ag |
Tableta ribocikliba
|
|
CN106146515B
(zh)
*
|
2015-04-17 |
2020-09-04 |
常州隆赛医药科技有限公司 |
新型激酶抑制剂的制备及应用
|
|
TWI696617B
(zh)
*
|
2015-04-28 |
2020-06-21 |
大陸商上海復尚慧創醫藥研究有限公司 |
特定蛋白質激酶抑制劑
|
|
US10124004B2
(en)
|
2015-05-29 |
2018-11-13 |
Teijin Pharma Limited |
Pyrido[3,4-d]pyrimidine derivative and pharmaceutically acceptable salt thereof
|
|
CN105037236B
(zh)
*
|
2015-06-04 |
2017-07-28 |
苏州明锐医药科技有限公司 |
瑞博西尼中间体及其制备方法
|
|
CN106336412A
(zh)
*
|
2015-07-10 |
2017-01-18 |
南开大学 |
作为cdk4/6抑制剂的2-(n-氧化芳环-2基氨基)-吡咯并嘧啶及嘌呤类化合物
|
|
CN106699785A
(zh)
*
|
2015-07-13 |
2017-05-24 |
南开大学 |
作为CDK4/6抑制剂的2-(N-氧化吡啶-2基氨基)-吡啶并[2,3-d]嘧啶-7-酮类化合物
|
|
CN105130992B
(zh)
*
|
2015-07-16 |
2018-02-09 |
苏州大学 |
具有激酶抑制活性的含氮杂环化合物、制备方法和用途
|
|
US20180340025A1
(en)
|
2015-07-29 |
2018-11-29 |
Novartis Ag |
Combination therapies comprising antibody molecules to lag-3
|
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
|
EP3328418A1
(en)
|
2015-07-29 |
2018-06-06 |
Novartis AG |
Combination therapies comprising antibody molecules to pd-1
|
|
WO2017037575A1
(en)
|
2015-08-28 |
2017-03-09 |
Novartis Ag |
A pharmaceutical combination comprising the pi3k inhibitor alpelisib and the cdk4/6 inhibitor ribociclib, and the use thereof in the treatment/prevention of cancer
|
|
US20180243304A1
(en)
*
|
2015-08-28 |
2018-08-30 |
Novartis Ag |
Pharmaceutical combinations comprising (a) the cyclin dependent kinase 4/6 (cdk4/6) inhibitor lee011 (=ribociclib), and (b) the epidermal growth factor receptor (egfr) inhibitor erlotinib, for the treatment or prevention of cancer
|
|
WO2017037587A1
(en)
|
2015-08-28 |
2017-03-09 |
Novartis Ag |
Combination of ribociclib and dabrafenib for treating or preventing cancer
|
|
WO2017037574A1
(en)
|
2015-08-28 |
2017-03-09 |
Novartis Ag |
Combinations of the cdk4/6 inhibitor lee011 and the mek1/2 inhibitor trametinib, optionally further comprising the pi3k inhibitor byl719 to treat cancer
|
|
EP3156406A1
(en)
|
2015-10-14 |
2017-04-19 |
ratiopharm GmbH |
Crystalline forms of ribociclib free base
|
|
CN108472289A
(zh)
|
2015-11-02 |
2018-08-31 |
诺华股份有限公司 |
磷脂酰肌醇3-激酶抑制剂的给药方案
|
|
PT3370768T
(pt)
|
2015-11-03 |
2022-04-21 |
Janssen Biotech Inc |
Anticorpos que se ligam especificamente ao pd-1 e seus usos
|
|
CA3002097A1
(en)
|
2015-11-12 |
2017-05-18 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
CN106749259B
(zh)
*
|
2015-11-19 |
2019-02-01 |
华东师范大学 |
一种环戊基嘧啶并吡咯类化合物的合成方法
|
|
CN106831780A
(zh)
*
|
2015-12-03 |
2017-06-13 |
南开大学 |
具有cdk4/6和hdac抑制活性的新型杂环衍生物
|
|
CN108495651A
(zh)
|
2015-12-17 |
2018-09-04 |
诺华股份有限公司 |
抗pd-1的抗体分子及其用途
|
|
CN105541863B
(zh)
*
|
2016-02-16 |
2017-09-05 |
安纳康科学股份有限公司 |
噻吩[2,3‑c]吡啶衍生物及其作为CDK激酶抑制剂的用途
|
|
US11921116B2
(en)
|
2016-03-09 |
2024-03-05 |
Memorial Sloan Kettering Cancer Center |
Enigma and CDH18 as companion diagnostics for CDK4 inhibitors
|
|
WO2017161253A1
(en)
|
2016-03-18 |
2017-09-21 |
Tufts Medical Center |
Compositions and methods for treating and preventing metabolic disorders
|
|
WO2017162215A1
(zh)
*
|
2016-03-25 |
2017-09-28 |
正大天晴药业集团股份有限公司 |
取代的吡咯并嘧啶类cdk抑制剂、包含其的药物组合物以及它们的用途
|
|
CN107266451B
(zh)
*
|
2016-04-07 |
2021-12-31 |
上海医药工业研究院 |
瑞布昔利布中间体的制备方法
|
|
WO2017185031A1
(en)
*
|
2016-04-22 |
2017-10-26 |
Dana-Farber Cancer Institute, Inc. |
Degradation of cyclin-dependent kinase 4/6 (cdk4/6) by conjugation of cdk4/6 inhibitors with e3 ligase ligand and methods of use
|
|
ES2954148T3
(es)
|
2016-05-07 |
2023-11-20 |
Fochon Pharmaceuticals Ltd |
Ciertos inhibidores de proteína cinasa
|
|
WO2017211245A1
(zh)
*
|
2016-06-06 |
2017-12-14 |
深圳市塔吉瑞生物医药有限公司 |
一种取代的吡咯并嘧啶化合物及其应用
|
|
KR102218333B1
(ko)
|
2016-06-07 |
2021-02-22 |
자코바이오 파마슈티칼스 컴퍼니 리미티드 |
Shp2 억제제로서 유용한 신규한 헤테로환형 유도체
|
|
WO2018005533A1
(en)
|
2016-07-01 |
2018-01-04 |
G1 Therapeutics, Inc. |
Antiproliferative pyrimidine-based compounds
|
|
WO2018005863A1
(en)
|
2016-07-01 |
2018-01-04 |
G1 Therapeutics, Inc. |
Pyrimidine-based compounds for the treatment of cancer
|
|
AU2017290362B2
(en)
|
2016-07-01 |
2021-08-05 |
Pharmacosmos Holding A/S |
Synthesis of N-(heteroaryl)-pyrrolo[3,2-d]pyrimidin-2-amines
|
|
CN109789143A
(zh)
*
|
2016-07-01 |
2019-05-21 |
G1治疗公司 |
基于嘧啶的抗增殖剂
|
|
EP3507367A4
(en)
|
2016-07-05 |
2020-03-25 |
Aduro BioTech, Inc. |
CYCLIC DINUCLEOTID COMPOUNDS WITH INCLUDED NUCLEIC ACIDS AND USES THEREOF
|
|
BR112019003722A2
(pt)
|
2016-08-23 |
2019-05-28 |
Eisai R&D Man Co Ltd |
terapias de combinação para o tratamento de carcinoma hepatocelular
|
|
WO2018051280A1
(en)
*
|
2016-09-15 |
2018-03-22 |
Dr. Reddy’S Laboratories Limited |
Process for preparation of ribociclib, its acid addition salts
|
|
CN109715163B
(zh)
|
2016-09-19 |
2022-11-22 |
诺华股份有限公司 |
包含raf抑制剂和erk抑制剂的治疗组合
|
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
|
CN109843297A
(zh)
|
2016-10-20 |
2019-06-04 |
辉瑞大药厂 |
治疗pah的抗增殖剂
|
|
WO2018081211A1
(en)
*
|
2016-10-26 |
2018-05-03 |
Li George Y |
Deuterated 7-cyclopentyl-n, n-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7h-pyrrolo[2,3-d]pyrimdine-6-carboxamide
|
|
US11865176B2
(en)
|
2016-11-08 |
2024-01-09 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods of modulating anti-tumor immunity
|
|
CN110177553A
(zh)
|
2016-11-17 |
2019-08-27 |
北卡罗来纳大学教堂山分校 |
烷基吡咯并嘧啶类似物及其制备和使用方法
|
|
WO2018094143A1
(en)
|
2016-11-17 |
2018-05-24 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
|
HUE053220T2
(hu)
|
2016-11-28 |
2021-06-28 |
Teijin Pharma Ltd |
((Piridin-2-il)-amino)pirido[3,4-d]pirimidin és ((piridazin-3-il)-amino)pirido[3,4-d]pirimidin származékok mint CDK4/6 inhibitorok pl. reumatoid artritisz, érelmeszesedés, tüdõfibrózis, agyi infartus vagy rák kezelésére
|
|
TWI755452B
(zh)
|
2016-11-28 |
2022-02-21 |
日商帝人製藥股份有限公司 |
吡啶并〔３﹐４-ｄ〕嘧啶衍生物或其溶劑合物之結晶
|
|
IL317919A
(en)
|
2016-12-05 |
2025-02-01 |
G1 Therapeutics Inc |
Preservation of immune response during chemotherapy regimens
|
|
JP7229162B2
(ja)
|
2017-01-06 |
2023-02-27 |
ジー１ セラピューティクス， インコーポレイテッド |
癌の治療に対する併用療法
|
|
WO2018140730A1
(en)
|
2017-01-27 |
2018-08-02 |
Signalrx Pharmaceuticals, Inc. |
Thienopyranones and furanopyranones as kinase, bromodomain, and checkpoint inhibitors
|
|
US11395821B2
(en)
|
2017-01-30 |
2022-07-26 |
G1 Therapeutics, Inc. |
Treatment of EGFR-driven cancer with fewer side effects
|
|
KR20240044544A
(ko)
|
2017-03-03 |
2024-04-04 |
씨젠 인크. |
글리칸-상호작용 화합물 및 사용 방법
|
|
WO2018170447A1
(en)
|
2017-03-16 |
2018-09-20 |
Eisai R&D Management Co., Ltd. |
Combination therapies for the treatment of breast cancer
|
|
SG11201908820VA
(en)
|
2017-03-23 |
2019-10-30 |
Jacobio Pharmaceuticals Co Ltd |
Novel heterocyclic derivatives useful as shp2 inhibitors
|
|
UY37695A
(es)
|
2017-04-28 |
2018-11-30 |
Novartis Ag |
Compuesto dinucleótido cíclico bis 2’-5’-rr-(3’f-a)(3’f-a) y usos del mismo
|
|
WO2018203219A1
(en)
|
2017-05-02 |
2018-11-08 |
Novartis Ag |
Combination therapy
|
|
CN107118215B
(zh)
*
|
2017-05-06 |
2019-04-05 |
上海耀大生物科技有限公司 |
一种治疗乳腺癌药物瑞博西尼中间体的制备方法
|
|
CN106946880B
(zh)
*
|
2017-05-06 |
2019-04-26 |
南京焕然生物科技有限公司 |
一种制备瑞博西尼中间体的方法
|
|
CN107267481A
(zh)
*
|
2017-05-09 |
2017-10-20 |
上海交通大学医学院附属新华医院 |
Cdk5抗原表位肽及其应用
|
|
CN108929324A
(zh)
*
|
2017-05-22 |
2018-12-04 |
南开大学 |
新型1,1-环丙基二酰胺衍生物的制备与应用
|
|
CN108929312A
(zh)
*
|
2017-05-22 |
2018-12-04 |
南开大学 |
具有cdk或hdac抑制活性的新型苯并杂环联嘧啶抑制剂
|
|
TW201906818A
(zh)
|
2017-05-31 |
2019-02-16 |
美商５１１製藥公司 |
新穎氘取代之正子發射斷層掃描（ｐｅｔ）顯影劑及其藥理應用
|
|
WO2018218633A1
(en)
|
2017-06-02 |
2018-12-06 |
Beijing Percans Oncology Co. Ltd. |
Combination therapies for treating cancers
|
|
US20200172628A1
(en)
|
2017-06-22 |
2020-06-04 |
Novartis Ag |
Antibody molecules to cd73 and uses thereof
|
|
EP3645001B1
(en)
|
2017-06-29 |
2024-07-03 |
G1 Therapeutics, Inc. |
Morphic forms of git38 and methods of manufacture thereof
|
|
EP3661519A1
(en)
|
2017-08-03 |
2020-06-10 |
Novartis AG |
Therapeutic combination of a third generation egfr tyrosine kinase inhibitor and a cyclin d kinase inhibitor
|
|
MX2020002123A
(es)
|
2017-08-25 |
2020-09-18 |
Sicor Soc It Corticosteroidi S R L |
Sales de ribociclib y formas en estado sólido de las mismas.
|
|
ES3049655T3
(en)
|
2017-08-31 |
2025-12-17 |
Novartis Ag |
Methods of selecting a treatment for breast cancer patients
|
|
WO2019062854A1
(zh)
*
|
2017-09-29 |
2019-04-04 |
杭州领业医药科技有限公司 |
瑞博西林的共晶和瑞博西林单琥珀酸盐的共晶、其制备方法、组合物和用途
|
|
CN111386272B
(zh)
*
|
2017-10-27 |
2023-01-06 |
费森尤斯卡比肿瘤学有限公司 |
一种改进的瑞博西尼及其盐的制备方法
|
|
US11179365B2
(en)
|
2017-11-16 |
2021-11-23 |
Novartis Ag |
Pharmaceutical combination comprising LSZ102 and ribociclib
|
|
MX2020004756A
(es)
|
2017-11-16 |
2020-08-20 |
Novartis Ag |
Terapias de combinacion.
|
|
WO2019123364A1
(en)
|
2017-12-22 |
2019-06-27 |
Shilpa Medicare Limited |
Novel polymorphs of ribociclib mono succinate
|
|
WO2019126731A1
(en)
*
|
2017-12-22 |
2019-06-27 |
Petra Pharma Corporation |
Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors
|
|
US10519136B2
(en)
*
|
2017-12-29 |
2019-12-31 |
Accutar Biotechnology |
Dual inhibitors of PARP1 and CDK
|
|
CN107936029B
(zh)
*
|
2018-01-08 |
2020-06-30 |
南京奇可药业有限公司 |
一种合成瑞博西尼的方法
|
|
WO2019136451A1
(en)
|
2018-01-08 |
2019-07-11 |
G1 Therapeutics, Inc. |
G1t38 superior dosage regimes
|
|
US12398209B2
(en)
|
2018-01-22 |
2025-08-26 |
Janssen Biotech, Inc. |
Methods of treating cancers with antagonistic anti-PD-1 antibodies
|
|
WO2019148161A1
(en)
*
|
2018-01-29 |
2019-08-01 |
Beta Pharma, Inc. |
2h-indazole derivatives as cdk4 and cdk6 inhibitors and therapeutic uses thereof
|
|
WO2019161224A1
(en)
|
2018-02-15 |
2019-08-22 |
GiraFpharma LLC |
Heterocyclic compounds as kinase inhibitors
|
|
WO2019167068A1
(en)
|
2018-03-01 |
2019-09-06 |
Cipla Limited |
Novel polymorphs of ribociclib succinate
|
|
WO2019195959A1
(en)
|
2018-04-08 |
2019-10-17 |
Cothera Biosciences, Inc. |
Combination therapy for cancers with braf mutation
|
|
CA3043066A1
(en)
|
2018-05-14 |
2019-11-14 |
Apotex Inc. |
Processes for the preparation of ribociclib and intermediates thereof
|
|
WO2019222521A1
(en)
*
|
2018-05-16 |
2019-11-21 |
G1 Therapeutics, Inc. |
Cdk inhibitors for the treatment of neoplastic disorders
|
|
CN108558745A
(zh)
*
|
2018-05-17 |
2018-09-21 |
苏州莱克施德药业有限公司 |
一种帕博西林中间体的合成方法
|
|
UY38247A
(es)
|
2018-05-30 |
2019-12-31 |
Novartis Ag |
Anticuerpos frente a entpd2, terapias de combinación y métodos de uso de los anticuerpos y las terapias de combinación
|
|
KR102695210B1
(ko)
|
2018-06-05 |
2024-08-13 |
크리네틱스 파마슈티칼스, 인크. |
멜라노코르틴 아형-2 수용체(mc2r) 길항제 및 이의 용도
|
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
|
WO2020023917A1
(en)
|
2018-07-27 |
2020-01-30 |
California Institute Of Technology |
Cdk inhibitors and uses thereof
|
|
WO2020036852A1
(en)
|
2018-08-13 |
2020-02-20 |
Beijing Percans Oncology Co. Ltd. |
Biomarkers for cancer therapy
|
|
KR102962306B1
(ko)
|
2018-08-24 |
2026-05-08 |
쥐원 쎄라퓨틱스, 인크. |
1,4-디아자스피로[5.5]운데칸-3-온의 개선된 합성
|
|
AU2019338032A1
(en)
*
|
2018-09-13 |
2021-05-20 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Salts of substituted pyrrolopyrimidine CDK inhibitor, crystal and use thereof
|
|
CN112839935A
(zh)
|
2018-09-26 |
2021-05-25 |
北京加科思新药研发有限公司 |
可用作shp2抑制剂的新型杂环衍生物
|
|
WO2020084389A1
(en)
|
2018-10-23 |
2020-04-30 |
Lupin Limited |
Ribociclib intermediate and process for preparation thereof
|
|
EP3873608A1
(en)
|
2018-10-31 |
2021-09-08 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
|
|
EP4371987B9
(en)
|
2018-10-31 |
2025-11-26 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds as hpk1 inhibitors
|
|
AU2019402189B2
(en)
|
2018-12-20 |
2023-04-13 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
CN109400612A
(zh)
*
|
2018-12-24 |
2019-03-01 |
重庆三圣实业股份有限公司 |
一种瑞博西尼的制备方法及其产品和用途
|
|
EP3902805A4
(en)
*
|
2018-12-28 |
2023-03-01 |
SPV Therapeutics Inc. |
CYCLINE-DEPENDENT KINASE INHIBITORS
|
|
US20220056037A1
(en)
*
|
2018-12-28 |
2022-02-24 |
Spv Therapeutics Inc. |
Cyclin-dependent kinase inhibitors
|
|
WO2020152629A1
(en)
|
2019-01-23 |
2020-07-30 |
Novartis Ag |
New crystalline forms of a succinate salt of 7-cyclopentyl-2-(5-piperazin-1-yl-pyridin-2-ylamino)-7h-pyrrolo[2,3-d]pyrimidine -6-carboxylic acid dimethylamide
|
|
US12343344B2
(en)
|
2019-02-12 |
2025-07-01 |
Novartis Ag |
Pharmaceutical combination comprising TNO155 and ribociclib
|
|
EP3924054B1
(en)
|
2019-02-15 |
2025-04-02 |
Novartis AG |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CA3123519A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
TW202521536A
(zh)
|
2019-05-05 |
2025-06-01 |
美商基尼特奇公司 |
Ｃｄｋ抑制劑
|
|
WO2020225827A1
(en)
|
2019-05-08 |
2020-11-12 |
Mylan Laboratories Limited |
Novel polymorphs of ribociclib succinate
|
|
CN114269734B
(zh)
*
|
2019-05-08 |
2026-03-27 |
维玛兰生物科学公司 |
Jak抑制剂
|
|
EP4563150A3
(en)
|
2019-05-13 |
2025-07-23 |
Novartis AG |
New crystalline forms of n-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methvlphenyl)-2(trifluoromethyl) isonicotinamide as raf inhibitors for the treatment of cancer
|
|
AU2020279979A1
(en)
|
2019-05-20 |
2021-11-25 |
Les Laboratoires Servier |
Mcl-1 inhibitor antibody-drug conjugates and methods of use
|
|
US11453681B2
(en)
|
2019-05-23 |
2022-09-27 |
Gilead Sciences, Inc. |
Substituted eneoxindoles and uses thereof
|
|
IL288508B2
(en)
*
|
2019-06-04 |
2026-02-01 |
Step Pharma S A S |
History of n-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonamido)pyrimidin-4-yl)tetrahydro-h2-pyran-4-carboxamide and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases
|
|
TW202112767A
(zh)
|
2019-06-17 |
2021-04-01 |
美商佩特拉製藥公司 |
作為磷脂酸肌醇磷酸激酶抑制劑之胺基吡啶衍生物
|
|
CN112094272A
(zh)
|
2019-06-18 |
2020-12-18 |
北京睿熙生物科技有限公司 |
Cdk激酶抑制剂
|
|
WO2021041348A1
(en)
|
2019-08-26 |
2021-03-04 |
Arvinas Operations, Inc. |
Methods of treating breast cancer with tetrahydronaphthalene derivatives as estrogen receptor degraders
|
|
WO2021038590A1
(en)
|
2019-08-30 |
2021-03-04 |
Mylan Laboratories Limited |
Novel polymorph of ribociclib succinate
|
|
JP2022548881A
(ja)
|
2019-09-18 |
2022-11-22 |
ノバルティス アーゲー |
Ｅｎｔｐｄ２抗体、組合せ療法並びに抗体及び組合せ療法を使用する方法
|
|
WO2021091788A1
(en)
*
|
2019-11-07 |
2021-05-14 |
Crinetics Pharmaceuticals, Inc. |
Melanocortin subtype-2 receptor (mc2r) antagonists and uses thereof
|
|
EP4077325B1
(en)
|
2019-12-16 |
2026-03-11 |
Lunella Biotech, Inc. |
Selective cdk4/6 inhibitor cancer therapeutics
|
|
IL293940B2
(en)
|
2019-12-16 |
2026-05-01 |
Lunella Biotech Inc |
Selective cancer drugs CDK4/6 inhibitors
|
|
JP7672406B2
(ja)
|
2019-12-18 |
2025-05-07 |
クリネティックス ファーマシューティカルズ，インク． |
Ｇｅｍ－二置換ピペリジンメラノコルチンサブタイプ－２受容体（ｍｃ２ｒ）アンタゴニストおよびその使用
|
|
US20230057071A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Combination of anti tim-3 antibody mbg453 and anti tgf-beta antibody nis793, with or without decitabine or the anti pd-1 antibody spartalizumab, for treating myelofibrosis and myelodysplastic syndrome
|
|
CN116234803B
(zh)
|
2019-12-23 |
2026-06-30 |
冰洲石生物科技公司 |
用于治疗癌症的雌激素受体降解剂和细胞周期蛋白依赖性激酶抑制剂的组合
|
|
JP7651574B2
(ja)
|
2019-12-23 |
2025-03-26 |
クリネティックス ファーマシューティカルズ，インク． |
スピロ環式ピペリジンメラノコルチンサブタイプ－２受容体（ｍｃ２ｒ）アンタゴニストおよびその使用
|
|
EP4126244A4
(en)
*
|
2020-03-27 |
2024-03-27 |
Jiangsu Alphamab Biopharmaceuticals Co., Ltd. |
COMBINATION OF ANTI-HER2 ANTIBODIES AND CDK INHIBITORS FOR TUMOR TREATMENT
|
|
AR121715A1
(es)
|
2020-04-03 |
2022-06-29 |
Biocryst Pharm Inc |
Pirrolopirimidinaminas como inhibidores del sistema del complemento
|
|
EP4141004A4
(en)
*
|
2020-05-12 |
2023-08-23 |
Suzhou Alphama Biotechnology Co., Ltd. |
POLYCYCLIC AMIDE DERIVATIVE SERVING AS A CDK9 INHIBITOR, METHOD FOR PREPARING IT AND ITS USE
|
|
WO2021229439A1
(en)
|
2020-05-12 |
2021-11-18 |
Novartis Ag |
Therapeutic combinations comprising a craf inhibitor
|
|
JP7451765B2
(ja)
*
|
2020-05-12 |
2024-03-18 |
蘇州阿尓脈生物科技有限公司 |
Ｃｄｋ阻害剤としてのピリジンアセトアミド系誘導体、その調製方法及び用途
|
|
JP7853532B2
(ja)
|
2020-05-19 |
2026-04-30 |
ファーマコスモス ホールディング エー／エス |
医学的障害を治療するためのサイクリン依存性キナーゼ阻害化合物
|
|
CN115698015A
(zh)
*
|
2020-06-11 |
2023-02-03 |
卢内拉生物技术有限公司 |
选择性cdk4/6抑制剂癌症治疗
|
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|
|
EP4168007A1
(en)
|
2020-06-23 |
2023-04-26 |
Novartis AG |
Dosing regimen comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
|
EP4188549A1
(en)
|
2020-08-03 |
2023-06-07 |
Novartis AG |
Heteroaryl substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
|
CN112375081B
(zh)
*
|
2020-11-23 |
2022-04-12 |
中国医学科学院医药生物技术研究所 |
具有抑制CDK4、6或9活性的吡咯[2,3-d]嘧啶衍生物及其制备方法和应用
|
|
MX2023006010A
(es)
|
2020-11-24 |
2023-06-08 |
Novartis Ag |
Anticuerpos anti-cd48, conjugados de anticuerpo-farmaco, y usos de los mismos.
|
|
JP2023553808A
(ja)
|
2020-11-24 |
2023-12-26 |
ノバルティス アーゲー |
Ｍｃｌ－１阻害剤抗体－薬物コンジュゲートおよび使用方法
|
|
WO2022162122A1
(en)
|
2021-01-29 |
2022-08-04 |
Biotx.Ai Gmbh |
Genetically verified netosis inhibitor for use in the treatment of a sars-cov2 infection
|
|
JP2024505562A
(ja)
|
2021-02-02 |
2024-02-06 |
レス ラボラトイレス セルビエル |
選択的ｂｃｌ－ｘｌ ｐｒｏｔａｃ化合物及び使用の方法
|
|
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(pt)
|
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|
|
WO2022207788A2
(en)
|
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|
|
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(zh)
|
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|
|
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|
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|
|
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(es)
|
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|
|
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(zh)
|
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|
|
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(ko)
|
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|
|
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(ko)
*
|
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|
|
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(zh)
|
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|
|
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(zh)
*
|
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用于治疗和/或预防恶性肿瘤的化合物及药物制剂和应用
|
|
US12275738B2
(en)
|
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CDK9 inhibitors
|
|
JP2025511975A
(ja)
*
|
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|
|
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(zh)
|
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|
|
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(en)
|
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Epha2 bcl-xl inhibitor antibody-drug conjugates and methods of use thereof
|
|
WO2024049926A1
(en)
|
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Dosage regimens of estrogen receptor degraders
|
|
EP4605088A1
(en)
*
|
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|
|
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(ja)
|
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|
|
EP4626890A1
(en)
|
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KRKA, d.d., Novo mesto |
Ribociclib salts and formulations thereof
|
|
EP4676540A1
(en)
|
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Panras inhibitor antibody-drug conjugates and methods of use thereof
|
|
KR20260019479A
(ko)
|
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|
|
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(zh)
|
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癌症療法
|
|
WO2024235844A1
(en)
|
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Institut National de la Santé et de la Recherche Médicale |
Methods of preventing on-target genotoxicity induced by nucleases
|
|
EP4730355A1
(en)
|
2023-05-18 |
2026-04-22 |
Lumitype Medical (Huzhou) Co., Ltd. |
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|
|
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(zh)
|
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锐新医药公司 |
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|
|
CN117069663B
(zh)
*
|
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|
|
EP4773947A1
(en)
|
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Afyx Development A/S |
Compositions and methods for treating and preventing oral cancer
|
|
EP4791378A1
(en)
*
|
2023-10-10 |
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Bifunctional protac and molecular glue compounds and methods of use thereof
|
|
AU2024360465A1
(en)
|
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Macrocyclic ras inhibitors
|
|
UY40985A
(es)
|
2023-11-22 |
2025-06-30 |
Servier Lab |
Conjugados de anticuerpo anti-cd74-fármaco y métodos de uso de los mismos
|
|
WO2025171296A1
(en)
|
2024-02-09 |
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Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2025217307A1
(en)
|
2024-04-09 |
2025-10-16 |
Revolution Medicines, Inc. |
Methods for predicting response to a ras(on) inhibitor and combination therapies
|
|
WO2025215536A1
(en)
|
2024-04-10 |
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Novartis Ag |
Macrocyclic panras inhibitors for the treatment of cancer
|
|
US20250319032A1
(en)
|
2024-04-15 |
2025-10-16 |
Novartis Ag |
Pharmaceutical compositions of ribociclib
|
|
WO2025235331A1
(en)
*
|
2024-05-07 |
2025-11-13 |
Nikang Therapeutics, Inc. |
Bifunctional compounds containing pyrazolopyrimidine derivatives for degrading certain cyclin-dependent kinase via ubiquitin proteasome pathway
|
|
WO2025240847A1
(en)
|
2024-05-17 |
2025-11-20 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
US20250375445A1
(en)
|
2024-06-07 |
2025-12-11 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2025265060A1
(en)
|
2024-06-21 |
2025-12-26 |
Revolution Medicines, Inc. |
Therapeutic compositions and methods for managing treatment-related effects
|
|
WO2026006747A1
(en)
|
2024-06-28 |
2026-01-02 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026015825A1
(en)
|
2024-07-12 |
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Revolution Medicines, Inc. |
Use of ras inhibitor for treating pancreatic cancer
|
|
WO2026015801A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015790A1
(en)
|
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2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026015796A1
(en)
|
2024-07-12 |
2026-01-15 |
Revolution Medicines, Inc. |
Methods of treating a ras related disease or disorder
|
|
WO2026038120A1
(en)
*
|
2024-08-12 |
2026-02-19 |
Novartis Ag |
Synthesis and crystalline forms of a cdk2 inhibitor
|
|
US20260053814A1
(en)
|
2024-08-21 |
2026-02-26 |
Celcuity Inc. |
Treatment regimens for gedatolisib in hormonally-driven disorders
|
|
WO2026050446A1
(en)
|
2024-08-29 |
2026-03-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026072904A2
(en)
|
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2026-04-02 |
Revolution Medicines, Inc. |
Compositions and methods for treating lung cancer
|
|
WO2026090116A2
(en)
|
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Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026090245A1
(en)
|
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2026-04-30 |
Revolution Medicines, Inc. |
Use of ras inhibitors for treating cancer
|
|
US20260108528A1
(en)
|
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2026-04-23 |
Revolution Medicines, Inc. |
Methods of treating a ras protein-related disease or disorder
|
|
WO2026106912A1
(en)
|
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2026-05-21 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026112260A1
(en)
|
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Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026122764A2
(en)
|
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Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026128391A1
(en)
|
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2026-06-18 |
Arvinas Operations, Inc. |
Combinations of vepdegestrant and cdk4/6 inhibitors for treating esr1-mutant breast cancer
|
|
WO2026128688A2
(en)
|
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Revolution Medicines, Inc. |
Ras inhibitors
|
|
WO2026161839A1
(en)
|
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2026-07-30 |
Revolution Medicines, Inc. |
Ras inhibitors
|
|
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(zh)
*
|
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|
|
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(zh)
*
|
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|