BRPI0917791B1 - Compostos de pirrolopirimidina como inibidores de cdk, bem como composição farmacêutica e combinação - Google Patents
Compostos de pirrolopirimidina como inibidores de cdk, bem como composição farmacêutica e combinação Download PDFInfo
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- BRPI0917791B1 BRPI0917791B1 BRPI0917791-4A BRPI0917791A BRPI0917791B1 BR PI0917791 B1 BRPI0917791 B1 BR PI0917791B1 BR PI0917791 A BRPI0917791 A BR PI0917791A BR PI0917791 B1 BRPI0917791 B1 BR PI0917791B1
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- Prior art keywords
- cyclopentyl
- pyrrolo
- pyridin
- pyrimidine
- ylamino
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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| US9103708P | 2008-08-22 | 2008-08-22 | |
| US61/091,037 | 2008-08-22 | ||
| PCT/EP2009/060793 WO2010020675A1 (en) | 2008-08-22 | 2009-08-20 | Pyrrolopyrimidine compounds as cdk inhibitors |
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| BRPI0917791B1 true BRPI0917791B1 (pt) | 2022-03-22 |
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