AU616564B2
(en)
*
|
1988-09-29 |
1991-10-31 |
Sumitomo Chemical Company, Limited |
Novel pyrazole compounds, method for production thereof, use thereof and intermediates for production thereof
|
DE4039733A1
(de)
*
|
1990-12-13 |
1992-06-17 |
Basf Ag |
Substituierte 5-aminopyrazole
|
NO179282C
(no)
*
|
1991-01-18 |
1996-09-11 |
Rhone Poulenc Agrochimie |
Nye 1-(2-pyridyl)pyrazolforbindelser til kontroll av skadeinsekter
|
AU1988692A
(en)
*
|
1991-04-24 |
1992-12-21 |
E.I. Du Pont De Nemours And Company |
Fungicidal pyrazoles, pyrazolines and tetrahydropyridazines
|
FR2682379B1
(fr)
*
|
1991-10-09 |
1994-02-11 |
Rhone Poulenc Agrochimie |
Nouveaux phenylpyrazoles fongicides.
|
US5550147A
(en)
*
|
1992-02-05 |
1996-08-27 |
Fujisawa Pharmaceutical Co., Ltd. |
Pyrazole derivatives, processes for preparation thereof and pharmaceutical composition comprising the same
|
IL104311A
(en)
*
|
1992-02-05 |
1997-07-13 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
|
FR2690440B1
(fr)
*
|
1992-04-27 |
1995-05-19 |
Rhone Poulenc Agrochimie |
Arylpyrazoles fongicides.
|
FR2713225B1
(fr)
*
|
1993-12-02 |
1996-03-01 |
Sanofi Sa |
N-pipéridino-3-pyrazolecarboxamide substitué.
|
FR2692575B1
(fr)
*
|
1992-06-23 |
1995-06-30 |
Sanofi Elf |
Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
US6492413B2
(en)
|
1993-01-15 |
2002-12-10 |
G.D. Searle & Co. |
3.4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
GB9420616D0
(en)
*
|
1994-10-12 |
1994-11-30 |
Merck Sharp & Dohme |
Method, compositions and use
|
US5380738A
(en)
*
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
US5840746A
(en)
*
|
1993-06-24 |
1998-11-24 |
Merck Frosst Canada, Inc. |
Use of inhibitors of cyclooxygenase in the treatment of neurodegenerative diseases
|
US5474995A
(en)
*
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
US5387602A
(en)
*
|
1993-08-30 |
1995-02-07 |
Ortho Pharmaceutical Corporation |
1.5-diphenyl-3-(N-hydroxycarbamoyloxyalkyl)pyrazoles
|
FR2711140B1
(fr)
*
|
1993-10-12 |
1996-01-05 |
Sanofi Sa |
1-Naphtylpyrazole-3-carboxamides substitués actifs sur la neurotensine, leur préparation, les compositions pharmaceutiques en contenant.
|
US5475018A
(en)
|
1993-11-30 |
1995-12-12 |
G. D. Searle & Co. |
1,5-diphenyl pyrazole compounds for treatment of inflammation
|
US5466823A
(en)
*
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
US6492411B1
(en)
|
1993-11-30 |
2002-12-10 |
G. D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
|
US5434178A
(en)
*
|
1993-11-30 |
1995-07-18 |
G.D. Searle & Co. |
1,3,5 trisubstituted pyrazole compounds for treatment of inflammation
|
US6716991B1
(en)
|
1993-11-30 |
2004-04-06 |
G. D. Searle & Co. |
Process for preparing a substituted pyrazolyl benzenesulfonamide for the treatment of inflammation
|
CA2276945C
(en)
*
|
1993-11-30 |
2006-08-01 |
G.D. Searle & Co. |
Tricyclic-substituted pyrazolyl benzenesulfonamides and pharmaceutical compositions thereof
|
US5401765A
(en)
*
|
1993-11-30 |
1995-03-28 |
G. D. Searle |
1,4,5-triphenyl pyrazolyl compounds for the treatment of inflammation and inflammation-related disorders
|
US5500439A
(en)
*
|
1993-12-09 |
1996-03-19 |
Alteon Inc. |
Aminopyrazoles
|
US5486534A
(en)
*
|
1994-07-21 |
1996-01-23 |
G. D. Searle & Co. |
3,4-substituted pyrazoles for the treatment of inflammation
|
US5908852A
(en)
*
|
1994-11-14 |
1999-06-01 |
G. D. Searle & Co. |
1,3,5 trisubstituted pyrazole compounds for treatment of inflammation
|
JP2636819B2
(ja)
|
1994-12-20 |
1997-07-30 |
日本たばこ産業株式会社 |
オキサゾール系複素環式芳香族化合物
|
CN1174970C
(zh)
*
|
1995-05-25 |
2004-11-10 |
G·D·瑟尔公司 |
3-卤代烷基-1h-吡唑的制备方法
|
US6512121B2
(en)
|
1998-09-14 |
2003-01-28 |
G.D. Searle & Co. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US6515014B2
(en)
|
1995-06-02 |
2003-02-04 |
G. D. Searle & Co. |
Thiophene substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
EP0828718A1
(en)
*
|
1995-06-02 |
1998-03-18 |
G.D. SEARLE & CO. |
Heterocyclo substituted hydroxamic acid derivatives as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
US5756529A
(en)
*
|
1995-09-29 |
1998-05-26 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies
|
GB9520584D0
(en)
*
|
1995-10-09 |
1995-12-13 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives,processes for preparation thereof and pharmaceutical composition comprising the same
|
US5908858A
(en)
*
|
1996-04-05 |
1999-06-01 |
Sankyo Company, Limited |
1,2-diphenylpyrrole derivatives, their preparation and their therapeutic uses
|
US6677364B2
(en)
*
|
1998-04-20 |
2004-01-13 |
G.D. Searle & Co. |
Substituted sulfonylphenylheterocycles as cyclooxygenase-2 and 5-lipoxygenase inhibitors
|
WO1998028269A1
(en)
*
|
1996-12-23 |
1998-07-02 |
Du Pont Pharmaceuticals Company |
NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS
|
JPH10324639A
(ja)
|
1997-03-21 |
1998-12-08 |
Chugai Pharmaceut Co Ltd |
Il−6アンタゴニストを有効成分として含有する感作t細胞関与疾患の予防・治療剤
|
US6979686B1
(en)
|
2001-12-07 |
2005-12-27 |
Pharmacia Corporation |
Substituted pyrazoles as p38 kinase inhibitors
|
WO1998052937A2
(en)
*
|
1997-05-22 |
1998-11-26 |
G.D. Searle And Co. |
4-aryl-3(5)-heteroaryl substituted pyrazoles as p38 kinase
|
US6514977B1
(en)
|
1997-05-22 |
2003-02-04 |
G.D. Searle & Company |
Substituted pyrazoles as p38 kinase inhibitors
|
WO1998052941A1
(en)
*
|
1997-05-22 |
1998-11-26 |
G.D. Searle And Co. |
PYRAZOLE DERIVATIVES AS p38 KINASE INHIBITORS
|
US6087496A
(en)
*
|
1998-05-22 |
2000-07-11 |
G. D. Searle & Co. |
Substituted pyrazoles suitable as p38 kinase inhibitors
|
KR20010013977A
(ko)
*
|
1997-06-19 |
2001-02-26 |
블레어 큐. 퍼거슨 |
중성 p1 특이성 기를 갖는 인자 xa의 억제제
|
US5998424A
(en)
|
1997-06-19 |
1999-12-07 |
Dupont Pharmaceuticals Company |
Inhibitors of factor Xa with a neutral P1 specificity group
|
AUPO941497A0
(en)
|
1997-09-24 |
1997-10-16 |
Fujisawa Pharmaceutical Co., Ltd. |
Novel compounds
|
AU750356B2
(en)
*
|
1997-09-24 |
2002-07-18 |
Fujisawa Pharmaceutical Co., Ltd. |
1,5-diphenylpyrazole derivatives
|
AU751139B2
(en)
*
|
1997-10-13 |
2002-08-08 |
Astellas Pharma Inc. |
Amide derivative
|
AUPP042397A0
(en)
*
|
1997-11-18 |
1997-12-11 |
Fujisawa Pharmaceutical Co., Ltd. |
5-arylpyrazole compounds
|
US6380249B1
(en)
|
1998-06-03 |
2002-04-30 |
Merck & Co., Inc. |
HIV integrase inhibitors
|
US6306891B1
(en)
|
1998-06-03 |
2001-10-23 |
Merck & Co., Inc. |
HIV integrase inhibitors
|
US6262055B1
(en)
*
|
1998-06-03 |
2001-07-17 |
Merck & Co., Inc. |
HIV integrase inhibitors
|
EP1082121A4
(en)
*
|
1998-06-03 |
2003-02-05 |
Merck & Co Inc |
INTEGRASE HIV INHIBITORS
|
AU4229999A
(en)
*
|
1998-06-05 |
1999-12-20 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Substituted 1-(4-aminophenyl)pyrazoles and their use as anti-inflammatory agents
|
TNSN99111A1
(fr)
*
|
1998-06-11 |
2005-11-10 |
Pfizer |
Derives de sulfonylbenzene nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
US6727238B2
(en)
|
1998-06-11 |
2004-04-27 |
Pfizer Inc. |
Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
|
US6294558B1
(en)
|
1999-05-31 |
2001-09-25 |
Pfizer Inc. |
Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
|
DE19831656A1
(de)
*
|
1998-07-15 |
2000-01-20 |
Basf Ag |
Verfahren zur Herstellung von Pyrazolen
|
GB9816358D0
(en)
*
|
1998-07-27 |
1998-09-23 |
Angeletti P Ist Richerche Bio |
Enzyme inhibitors
|
US6492423B1
(en)
|
1998-07-27 |
2002-12-10 |
Istituto Di Ricerche Di Biologia Molecolare Pangeletti Spa |
Diketoacid-derivatives as inhibitors of polymerases
|
USRE39708E1
(en)
|
1998-08-07 |
2007-06-26 |
Chiron Corporation |
Estrogen receptor modulators
|
US6291190B1
(en)
*
|
1998-08-25 |
2001-09-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Molecular differences between species of the M. tuberculosis complex
|
US6191147B1
(en)
*
|
1998-12-24 |
2001-02-20 |
Ppd Discovery, Inc. |
Pyrazole compounds and uses thereof
|
HUP0201472A3
(en)
|
1998-12-25 |
2006-03-28 |
Shionogi & Co |
Aromatic heterocycle compounds having hiv integrase inhibiting activities
|
DE19904397A1
(de)
*
|
1999-02-04 |
2000-08-10 |
Bayer Ag |
Verwendung von Pyrazol-Carbonsäureamiden
|
BR0009322A
(pt)
*
|
1999-03-26 |
2002-04-30 |
Euro Celtique Sa |
Pirazóis, imidazóis, oxazóis, tiazóis e pirróis substituìdos com arila e o uso dos mesmos
|
CA2379421A1
(en)
*
|
1999-08-27 |
2001-03-08 |
Abbott Laboratories |
Sulfonylphenylpyrazole compounds useful as cox-2 inhibitors
|
JP2003517475A
(ja)
*
|
1999-12-03 |
2003-05-27 |
ファイザー・プロダクツ・インク |
抗炎症/鎮痛薬としてのヘテロシクロ−アルキルスルホニルピラゾール誘導体
|
ATE252576T1
(de)
|
1999-12-03 |
2003-11-15 |
Pfizer Prod Inc |
Heteroarylphenylpyrazolverbindungen zur verwendung als analgetisches/entzündungshemmendes mittel
|
DK1104758T3
(da)
|
1999-12-03 |
2003-10-20 |
Pfizer Prod Inc |
Acetylenderivativer som anti-inflammatoriske/analgesiske lægemidler
|
DK1104760T3
(da)
|
1999-12-03 |
2003-06-30 |
Pfizer Prod Inc |
Sulfamoylheteroarylpyrazolforbindelser som anti-inflammatoriske/analgetiske midler
|
US6569885B1
(en)
*
|
1999-12-23 |
2003-05-27 |
Icos Corporation |
Cyclic AMP-specific phosphodiesterase inhibitors
|
US6372752B1
(en)
*
|
2000-02-07 |
2002-04-16 |
Genzyme Corporation |
Inha inhibitors and methods of use thereof
|
AU2001232175B2
(en)
|
2000-03-03 |
2005-07-07 |
Pfizer Products Inc. |
Pyrazole ether derivatives as anti-inflammatory/analgesic agents
|
PL214230B1
(pl)
*
|
2000-03-24 |
2013-07-31 |
Euro Celtique Sa |
Podstawione arylem pirazole i triazole, kompozycja farmaceutyczna je zawierajaca oraz ich zastosowanie
|
CA2433623A1
(en)
*
|
2001-01-02 |
2002-07-18 |
Fujisawa Pharmaceutical Co., Ltd. |
Pyridine derivatives useful as cyclooxygenase inhibitor
|
US20030105144A1
(en)
|
2001-04-17 |
2003-06-05 |
Ping Gao |
Stabilized oral pharmaceutical composition
|
US6673818B2
(en)
|
2001-04-20 |
2004-01-06 |
Pharmacia Corporation |
Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
|
US7041685B2
(en)
*
|
2001-06-08 |
2006-05-09 |
Cytovia, Inc. |
Substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
ES2241964T3
(es)
|
2001-07-05 |
2005-11-01 |
Pfizer Products Inc. |
Heterocicloalquilsulfufonilpirazoles como agentes antiinflamatorios/abnalgesicos.
|
US7076539B2
(en)
*
|
2001-07-30 |
2006-07-11 |
Hewlett-Packard Development Company, L.P. |
Network connectivity establishment at user log-in
|
US6849653B2
(en)
*
|
2001-09-19 |
2005-02-01 |
Pharmacia Corporation |
Substituted pyrazolyl benzenesulfamide compounds for the treatment of inflammation
|
WO2003024935A2
(en)
*
|
2001-09-19 |
2003-03-27 |
Pharmacia Corporation |
Substituted pyrazolyl compounds for the treatment of inflammation
|
US7057049B2
(en)
*
|
2001-09-25 |
2006-06-06 |
Pharmacia Corporation |
Process for making substituted pyrazoles
|
IL161009A0
(en)
|
2001-09-25 |
2004-08-31 |
Pharmacia Corp |
Process for making substituted pyrazoles
|
GT200200183A
(es)
|
2001-09-28 |
2003-05-23 |
|
Procedimiento para preparar derivados de heterocicloalquilsulfonil pirazol
|
WO2003037336A1
(en)
|
2001-11-02 |
2003-05-08 |
Pfizer Products Inc. |
1-(5-sulfonyl-pyridin-2-yl)-5-(methylidene-cycloalkylmethoxy)-1h-pyrazole-4-carbonitrile derivatives and other compounds as cyclooxygenase inhibitors for the treatment of arthritis, neurodegeneration and colon cancer
|
WO2003049678A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
CA2477931C
(en)
*
|
2002-03-05 |
2011-02-01 |
Josef Ehrenfreund |
O-cyclopropyl-carboxanilides and their use as fungicides
|
AU2003249597B2
(en)
*
|
2002-03-08 |
2007-06-28 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
AR038967A1
(es)
*
|
2002-03-18 |
2005-02-02 |
Solvay Pharm Bv |
Derivados de 2,3 - diaril - pirazolidinas como inhibidores de enzimas que degradan la neurotensina
|
US7329401B2
(en)
*
|
2002-04-15 |
2008-02-12 |
The Regents Of The University Of California |
Cyclooxygenase-2 selective agents useful as imaging probes and related methods
|
PL373807A1
(en)
|
2002-05-24 |
2005-09-19 |
Pharmacia Corporation |
Synthesis of diaryl pyrazoles
|
ATE446094T1
(de)
|
2002-06-14 |
2009-11-15 |
Merck & Co Inc |
Mitotische kinesin-hemmer
|
EP1539679A4
(en)
*
|
2002-06-28 |
2007-07-04 |
Nitromed Inc |
OXIM- AND / OR HYDRAZO-CONTAINING, NITROSED AND / OR NITROSYLATED CYCLOOXIGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND USE METHODS
|
AU2003265394A1
(en)
*
|
2002-08-14 |
2004-03-03 |
Ppd Discovery, Inc. |
Prenylation inhibitors containing dimethyl-cyclobutane and methods of their synthesis and use
|
US7166619B2
(en)
*
|
2002-08-14 |
2007-01-23 |
Ppd Discovery , Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
US6649638B1
(en)
*
|
2002-08-14 |
2003-11-18 |
Ppd Discovery, Inc. |
Prenylation inhibitors and methods of their synthesis and use
|
JP2006506366A
(ja)
*
|
2002-10-18 |
2006-02-23 |
ファイザー・プロダクツ・インク |
カンナビノイド受容体リガンドおよびその使用方法
|
US7129239B2
(en)
*
|
2002-10-28 |
2006-10-31 |
Pfizer Inc. |
Purine compounds and uses thereof
|
MXPA05005742A
(es)
*
|
2002-12-02 |
2005-08-16 |
Astellas Pharma Inc |
Derivados de pirazol utiles como inhibidores de cox-i.
|
US7247628B2
(en)
*
|
2002-12-12 |
2007-07-24 |
Pfizer, Inc. |
Cannabinoid receptor ligands and uses thereof
|
EP1581213A4
(en)
*
|
2002-12-18 |
2008-11-19 |
Cytovia Inc |
3,5-DISUBSTITUES-1,2,4-OXADIAZOLES AND ANALOGS AS ACTIVATORS OF CASPASES AND APOPTOSIS PROMOTERS, AND USE THEREOF
|
US7329658B2
(en)
*
|
2003-02-06 |
2008-02-12 |
Pfizer Inc |
Cannabinoid receptor ligands and uses thereof
|
CN100436445C
(zh)
*
|
2003-02-07 |
2008-11-26 |
第一制药株式会社 |
吡唑衍生物
|
PL377848A1
(pl)
*
|
2003-02-07 |
2006-02-20 |
Daiichi Pharmaceutical Co., Ltd. |
Pochodne pirazoli
|
US7176210B2
(en)
*
|
2003-02-10 |
2007-02-13 |
Pfizer Inc. |
Cannabinoid receptor ligands and uses thereof
|
US7145012B2
(en)
*
|
2003-04-23 |
2006-12-05 |
Pfizer Inc. |
Cannabinoid receptor ligands and uses thereof
|
US7141669B2
(en)
*
|
2003-04-23 |
2006-11-28 |
Pfizer Inc. |
Cannabiniod receptor ligands and uses thereof
|
US20040214856A1
(en)
*
|
2003-04-23 |
2004-10-28 |
Pfizer Inc |
Cannabinoid receptor ligands and uses thereof
|
US7268133B2
(en)
*
|
2003-04-23 |
2007-09-11 |
Pfizer, Inc. Patent Department |
Cannabinoid receptor ligands and uses thereof
|
MXPA05011922A
(es)
*
|
2003-05-07 |
2006-02-17 |
Pfizer Prod Inc |
Ligandos del receptor de cannabinoides y sus usos.
|
US7232823B2
(en)
|
2003-06-09 |
2007-06-19 |
Pfizer, Inc. |
Cannabinoid receptor ligands and uses thereof
|
US20040259887A1
(en)
*
|
2003-06-18 |
2004-12-23 |
Pfizer Inc |
Cannabinoid receptor ligands and uses thereof
|
CA2533889A1
(en)
|
2003-08-15 |
2005-03-03 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
AU2004264533B2
(en)
|
2003-08-15 |
2009-01-22 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
US20060079566A1
(en)
*
|
2003-10-03 |
2006-04-13 |
Ching-Shih Chen |
PDK-1/Akt signaling inhibitors
|
TW200526641A
(en)
*
|
2003-12-26 |
2005-08-16 |
Daiichi Seiyaku Co |
Amidopyrazole derivatives
|
JP2007084437A
(ja)
*
|
2003-12-26 |
2007-04-05 |
Dai Ichi Seiyaku Co Ltd |
アミノアルキルピラゾール誘導体
|
DE602005023730D1
(de)
|
2004-07-01 |
2010-11-04 |
Merck Sharp & Dohme |
Inhibitoren von mitotischem kinesin
|
CA2571821A1
(en)
*
|
2004-07-01 |
2006-01-19 |
Merck & Co., Inc. |
Prodrugs of mitotic kinesin inhibitors
|
AU2005262378A1
(en)
*
|
2004-07-01 |
2006-01-19 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
CN1980911A
(zh)
*
|
2004-07-01 |
2007-06-13 |
默克公司 |
有丝分裂驱动蛋白抑制剂
|
EP1785418A4
(en)
*
|
2004-08-06 |
2009-11-11 |
Daiichi Seiyaku Co |
PYRAZOLE DERIVATIVE
|
JPWO2006013962A1
(ja)
*
|
2004-08-06 |
2008-05-01 |
第一製薬株式会社 |
抗血小板薬およびその製造方法
|
AU2006235022B2
(en)
*
|
2005-04-07 |
2011-07-21 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
ATE550019T1
(de)
|
2005-05-17 |
2012-04-15 |
Merck Sharp & Dohme |
Cis-4-ä(4-chlorophenyl)sulfonylü-4-(2,5- difluorophenyl)cyclohexanepropansäure zur behandlug von krebs
|
WO2006133926A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Carex Sa |
Pyrazole derivates as cannabinoid receptor modulators
|
CA2613522A1
(en)
*
|
2005-06-27 |
2007-01-04 |
Exelixis, Inc. |
Imidazole based lxr modulators
|
PE20070335A1
(es)
*
|
2005-08-30 |
2007-04-21 |
Novartis Ag |
Benzimidazoles sustituidos y metodos para su preparacion
|
US20090062302A1
(en)
|
2006-01-24 |
2009-03-05 |
Buser-Doepner Carolyn A |
Jak2 Tyrosine Kinase Inhibition
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
ES2654847T3
(es)
|
2006-04-19 |
2018-02-15 |
Novartis Ag |
Compuestos de benzoxazol y benzotiazol sustituidos en 6-O y métodos para inhibir la señalización CSF-1R
|
EP2698157B1
(en)
|
2006-09-22 |
2015-05-20 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
JP5269795B2
(ja)
*
|
2006-09-29 |
2013-08-21 |
グリーン・クロス・コーポレイション |
カンナビノイドcb1受容体アンタゴニストとしてのヘテロアリール−ピラゾール誘導体
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
EP2109608B1
(en)
|
2007-01-10 |
2011-03-23 |
Istituto di Richerche di Biologia Molecolare P. Angeletti S.p.A. |
Amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
|
JP2010516679A
(ja)
*
|
2007-01-19 |
2010-05-20 |
マリンクロット インコーポレイテッド |
診断用および治療用シクロオキシゲナーゼ−2結合リガンド
|
US20080207704A1
(en)
*
|
2007-02-27 |
2008-08-28 |
The Green Cross Corporation |
Heteroaryl-imidazole derivatives as cannabinoid cb1 receptor antagonists
|
MX2009009304A
(es)
|
2007-03-01 |
2009-11-18 |
Novartis Ag |
Inhibidores de cinasa pim y metodos para su uso.
|
US20100120839A1
(en)
*
|
2007-04-20 |
2010-05-13 |
Biolipox Ab |
Pyrazoles useful in the treatment of inflammation
|
CN101754965B
(zh)
|
2007-05-21 |
2014-03-19 |
诺华股份有限公司 |
Csf-1r抑制剂、组合物及使用方法
|
CN101679281B
(zh)
*
|
2007-05-31 |
2013-09-11 |
先正达参股股份有限公司 |
吡唑的制备方法
|
US8389553B2
(en)
|
2007-06-27 |
2013-03-05 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
US8039502B2
(en)
|
2007-07-24 |
2011-10-18 |
The Ohio State University Research Foundation |
Anti-infective agents against intracellular pathogens
|
US7977358B2
(en)
*
|
2007-07-26 |
2011-07-12 |
Hoffmann-La Roche Inc. |
Pyrazol derivatives
|
AU2008299220B2
(en)
|
2007-09-10 |
2011-07-21 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
US20110009463A1
(en)
*
|
2007-10-17 |
2011-01-13 |
Yuri Karl Petersson |
Geranylgeranyl transferase inhibitors and methods of making and using the same
|
WO2009078498A1
(en)
*
|
2007-12-17 |
2009-06-25 |
Green Cross Corporation |
Biarylpyrazole 4-carboxamides as cannabinoid cb1 receptor ligands
|
US9029411B2
(en)
|
2008-01-25 |
2015-05-12 |
Millennium Pharmaceuticals, Inc. |
Thiophenes and uses thereof
|
CN102014631A
(zh)
|
2008-03-03 |
2011-04-13 |
泰格尔医药科技公司 |
酪氨酸激酶抑制剂
|
DE102008015032A1
(de)
|
2008-03-17 |
2009-09-24 |
Aicuris Gmbh & Co. Kg |
Substituierte Pyrazolamide und ihre Verwendung
|
DE102008015033A1
(de)
|
2008-03-17 |
2009-09-24 |
Aicuris Gmbh & Co. Kg |
Substituierte (Pyrazolyl-carbonyl)imidazolidinone und ihre Verwendung
|
ES2714453T3
(es)
*
|
2008-06-09 |
2019-05-28 |
Univ Muenchen Ludwig Maximilians |
Fármacos para inhibir la agregación de proteínas implicadas en enfermedades relacionadas con enfermedades neurodegenerativas y/o agregación de proteínas
|
US20110144056A1
(en)
*
|
2008-06-11 |
2011-06-16 |
Lin Linus S |
Pyrazole derivatives useful as inhibitors of faah
|
MX2011002149A
(es)
|
2008-08-27 |
2011-04-05 |
Calcimedica Inc |
Compuestos que modulan el calcio intracelular.
|
DE102008062863A1
(de)
|
2008-12-17 |
2010-06-24 |
Aicuris Gmbh & Co. Kg |
Substituierte (Thiophenyl-carbonyl)imidazolidinone und ihre Verwendung
|
DE102008062878A1
(de)
|
2008-12-17 |
2010-06-24 |
Aicuris Gmbh & Co. Kg |
Substituierte Furancarboxamide und ihre Verwendung
|
US8796314B2
(en)
|
2009-01-30 |
2014-08-05 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
CN102395585A
(zh)
|
2009-01-30 |
2012-03-28 |
米伦纽姆医药公司 |
杂芳基化合物和其作为pi3k抑制剂的用途
|
US9090601B2
(en)
|
2009-01-30 |
2015-07-28 |
Millennium Pharmaceuticals, Inc. |
Thiazole derivatives
|
US20120108823A1
(en)
|
2009-04-22 |
2012-05-03 |
The Ohio State University Research Foundation |
Anti-francisella agents
|
DE102009036604A1
(de)
|
2009-07-30 |
2011-02-03 |
Aicuris Gmbh & Co. Kg |
Substituierte Bis-Arylpyrazolamide mit terminaler primärer Amidfunktionalisierung und ihre Verwendung
|
EP2488028B1
(en)
|
2009-10-14 |
2020-08-19 |
Merck Sharp & Dohme Corp. |
Substituted piperidines that increase p53 activity and the uses thereof
|
DK2563776T3
(en)
|
2010-04-27 |
2016-09-19 |
Calcimedica Inc |
Relations that modulate intracellular calcium
|
JP2013525448A
(ja)
|
2010-04-27 |
2013-06-20 |
カルシメディカ,インク. |
細胞内カルシウムを調節する化合物
|
WO2011163330A1
(en)
|
2010-06-24 |
2011-12-29 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
CN103068980B
(zh)
|
2010-08-02 |
2017-04-05 |
瑟纳治疗公司 |
使用短干扰核酸(siNA)的RNA干扰介导的联蛋白(钙粘蛋白关联蛋白质),β1(CTNNB1)基因表达的抑制
|
PE20131304A1
(es)
|
2010-08-11 |
2013-11-14 |
Millennium Pharm Inc |
Heteroarilos y sus usos
|
JP2013533318A
(ja)
|
2010-08-11 |
2013-08-22 |
ミレニアム ファーマシューティカルズ, インコーポレイテッド |
ヘテロアリールおよびその使用
|
US9062038B2
(en)
|
2010-08-11 |
2015-06-23 |
Millennium Pharmaceuticals, Inc. |
Heteroaryls and uses thereof
|
KR102072631B1
(ko)
|
2010-08-17 |
2020-02-03 |
시르나 쎄러퓨틱스 인코퍼레이티드 |
짧은 간섭 핵산 (siNA)을 사용한 B형 간염 바이러스 (HBV) 유전자 발현의 RNA 간섭 매개 억제
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
CN103180316A
(zh)
|
2010-08-27 |
2013-06-26 |
钙医学公司 |
调节细胞内钙的化合物
|
US8580805B2
(en)
*
|
2010-08-31 |
2013-11-12 |
Hubert Maehr |
Pyrimidine carboxamide derivatives
|
WO2012030685A2
(en)
|
2010-09-01 |
2012-03-08 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
UY33671A
(es)
|
2010-10-13 |
2012-04-30 |
Millenium Pharmaceuticals Inc |
Heteroarilos y sus usos
|
EP3766975A1
(en)
|
2010-10-29 |
2021-01-20 |
Sirna Therapeutics, Inc. |
Rna interference mediated inhibition of gene expression using short interfering nucleic acid (sina)
|
WO2012087772A1
(en)
|
2010-12-21 |
2012-06-28 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
US20140046059A1
(en)
|
2011-04-21 |
2014-02-13 |
Piramal Enterprises Limited |
Process for the preparation of morpholino sulfonyl indole derivatives
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
EP2773207B1
(en)
|
2011-10-31 |
2018-03-07 |
Merck Sharp & Dohme Corp. |
Aminopyrimidinones as interleukin receptor-associated kinase inhibitors
|
DE102011055815A1
(de)
|
2011-11-29 |
2013-05-29 |
Aicuris Gmbh & Co. Kg |
Carboxamid-substituierte Heteroaryl-Pyrazole und ihre Verwendung
|
TW201332988A
(zh)
*
|
2011-12-23 |
2013-08-16 |
Millennium Pharm Inc |
雜芳基化合物及其用途
|
US20150299696A1
(en)
|
2012-05-02 |
2015-10-22 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
WO2014022382A2
(en)
*
|
2012-07-30 |
2014-02-06 |
The Ohio State University |
Antibacterial protein kinase inhibitors
|
DE102012016908A1
(de)
|
2012-08-17 |
2014-02-20 |
Aicuris Gmbh & Co. Kg |
Tris-(Hetero)Aryl-Pyrazole und ihre Verwendung
|
WO2014052563A2
(en)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
US9512116B2
(en)
|
2012-10-12 |
2016-12-06 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
ES2651347T3
(es)
|
2012-11-28 |
2018-01-25 |
Merck Sharp & Dohme Corp. |
Composiciones y métodos para el tratamiento del cáncer
|
CA2895504A1
(en)
|
2012-12-20 |
2014-06-26 |
Merck Sharp & Dohme Corp. |
Substituted imidazopyridines as hdm2 inhibitors
|
US9540377B2
(en)
|
2013-01-30 |
2017-01-10 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as HDM2 inhibitors
|
CN103265537B
(zh)
*
|
2013-05-14 |
2015-05-27 |
浙江医药高等专科学校 |
抗肿瘤化合物、其制备方法和用途
|
US20160166576A1
(en)
|
2013-07-11 |
2016-06-16 |
Merck Sharp & Dohme Corp. |
Substituted amidopyrazole inhibitors of interleukin receptor-associated kinases (irak-4)
|
MY176807A
(en)
|
2013-07-31 |
2020-08-21 |
Council Scient Ind Res |
Novel indazole compounds and a process for the preparation thereof
|
WO2015034925A1
(en)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
US9611263B2
(en)
|
2013-10-08 |
2017-04-04 |
Calcimedica, Inc. |
Compounds that modulate intracellular calcium
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
KR101650476B1
(ko)
*
|
2015-02-06 |
2016-08-23 |
한국건설기술연구원 |
중공슬래브를 위한 중공체의 부력방지장치
|
EP3268367B8
(en)
|
2015-03-12 |
2022-11-16 |
Merck Sharp & Dohme LLC |
Carboxamide inhibitors of irak4 activity
|
US10040802B2
(en)
|
2015-03-12 |
2018-08-07 |
Merck Sharp & Dohme Corp. |
Thienopyrazine inhibitors of IRAK4 activity
|
US10329294B2
(en)
|
2015-03-12 |
2019-06-25 |
Merck Sharp & Dohme Corp. |
Pyrazolopyrimidine inhibitors of IRAK4 activity
|
AR112900A1
(es)
|
2017-09-13 |
2019-12-26 |
Hanmi Pharm Ind Co Ltd |
Compuesto derivado de pirazol y uso de este
|
US10947234B2
(en)
|
2017-11-08 |
2021-03-16 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
WO2020033284A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2020033282A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
WO2021126731A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
CN112961109B
(zh)
*
|
2021-01-27 |
2022-05-17 |
台州学院 |
一种1,4-双磺酰化的全取代吡唑类化合物及其制备和应用
|