PT94628B - Processo para a preparacao de formulacoes contendo peptidos soluveis em agua de libertacao retardada - Google Patents

Processo para a preparacao de formulacoes contendo peptidos soluveis em agua de libertacao retardada Download PDF

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Publication number
PT94628B
PT94628B PT94628A PT9462890A PT94628B PT 94628 B PT94628 B PT 94628B PT 94628 A PT94628 A PT 94628A PT 9462890 A PT9462890 A PT 9462890A PT 94628 B PT94628 B PT 94628B
Authority
PT
Portugal
Prior art keywords
water
active substance
microparticles
polymer
delayed
Prior art date
Application number
PT94628A
Other languages
English (en)
Portuguese (pt)
Other versions
PT94628A (pt
Inventor
David Bodmer
Jones Wing Fong
Thomas Kissel
Hawkins Valliant Maulding
Oscar Nagele
Jane Edna Pearson
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of PT94628A publication Critical patent/PT94628A/pt
Publication of PT94628B publication Critical patent/PT94628B/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT94628A 1989-07-07 1990-07-06 Processo para a preparacao de formulacoes contendo peptidos soluveis em agua de libertacao retardada PT94628B (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (2)

Publication Number Publication Date
PT94628A PT94628A (pt) 1991-03-20
PT94628B true PT94628B (pt) 1997-06-30

Family

ID=27007654

Family Applications (1)

Application Number Title Priority Date Filing Date
PT94628A PT94628B (pt) 1989-07-07 1990-07-06 Processo para a preparacao de formulacoes contendo peptidos soluveis em agua de libertacao retardada

Country Status (27)

Country Link
JP (5) JPH0832624B2 (he)
KR (2) KR100303681B1 (he)
AT (1) AT406225B (he)
AU (2) AU641407B2 (he)
BE (1) BE1004486A3 (he)
CA (1) CA2020477C (he)
CH (1) CH685230A5 (he)
CY (1) CY1965A (he)
DE (2) DE4021517B4 (he)
DK (1) DK175849B1 (he)
FI (3) FI108611B (he)
FR (1) FR2649319A1 (he)
GB (2) GB2234896B (he)
GR (1) GR1001121B (he)
HK (2) HK97695A (he)
HU (2) HU221294B1 (he)
IE (2) IE64411B1 (he)
IL (3) IL131881A (he)
IT (1) IT1241460B (he)
LU (1) LU87764A1 (he)
MY (1) MY106722A (he)
NL (1) NL195027C (he)
NO (2) NO302928B1 (he)
NZ (1) NZ234384A (he)
PT (1) PT94628B (he)
SE (1) SE512992C2 (he)
SG (1) SG26416G (he)

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KR20130024987A (ko) * 2005-12-22 2013-03-08 노파르티스 아게 옥트레오티드 및 ２종 이상의 폴리락티드-코-글리콜리드 중합체를 포함하는 서방형 제제
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JP5791278B2 (ja) 2008-01-30 2015-10-07 ノバルティス アーゲー オクトレオチドおよび３種の線状ポリラクチド−コ−グリコリドポリマーを含む徐放性製剤
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Also Published As

Publication number Publication date
NO903001D0 (no) 1990-07-05
DK162590A (da) 1991-01-08
FR2649319B1 (he) 1994-12-09
PT94628A (pt) 1991-03-20
NO983923D0 (no) 1998-08-26
NL195027B (nl) 2003-08-01
FI108611B (fi) 2002-02-28
SE512992C2 (sv) 2000-06-12
NL9001537A (nl) 1991-02-01
JPH07309897A (ja) 1995-11-28
HU903974D0 (en) 1990-11-28
JPH07285853A (ja) 1995-10-31
FI109543B (fi) 2002-08-30
JPH08198771A (ja) 1996-08-06
FI20000059A (fi) 2000-01-12
NO302928B1 (no) 1998-05-11
HUT54037A (en) 1991-01-28
CH685230A5 (de) 1995-05-15
GB2234896A (en) 1991-02-20
IL131881A (he) 2001-12-23
MY106722A (en) 1995-07-31
ATA144090A (de) 1999-08-15
HK97695A (en) 1995-06-23
KR100303681B1 (ko) 2002-05-16
GB2265311A (en) 1993-09-29
IE64411B1 (en) 1995-08-09
JPH0368511A (ja) 1991-03-25
DK162590D0 (da) 1990-07-05
DE4021517B4 (de) 2009-04-09
JP2931773B2 (ja) 1999-08-09
GB9014704D0 (en) 1990-08-22
JPH0832624B2 (ja) 1996-03-29
AT406225B (de) 2000-03-27
AU2332195A (en) 1995-09-07
LU87764A1 (fr) 1992-03-11
NO903001L (no) 1991-01-08
FI903429A0 (fi) 1990-07-06
DE4042752B4 (de) 2009-05-07
CY1965A (en) 1997-07-04
AU5874690A (en) 1991-01-10
NO983923L (no) 1991-01-08
AU687553B2 (en) 1998-02-26
GB2234896B (en) 1994-01-19
DK175849B1 (da) 2005-03-29
IE902435A1 (en) 1991-02-13
IL94983A (he) 1999-08-17
SE9002364L (sv) 1991-01-08
NZ234384A (en) 1994-05-26
GB9306204D0 (en) 1993-05-19
NL195027C (nl) 2003-12-02
IT9048113A0 (it) 1990-07-05
BE1004486A3 (fr) 1992-12-01
GR900100513A (en) 1991-12-10
CA2020477A1 (en) 1991-01-08
IT9048113A1 (it) 1992-01-05
IL131880A (he) 2001-12-23
FR2649319A1 (fr) 1991-01-11
KR910002430A (ko) 1991-02-25
CA2020477C (en) 2000-11-21
IE64216B1 (en) 1995-07-26
FI109334B (fi) 2002-07-15
KR100442931B1 (ko) 2004-08-02
HU211602A9 (en) 1995-12-28
SE9002364D0 (sv) 1990-07-05
JP2001233897A (ja) 2001-08-28
FI20000060A (fi) 2000-01-12
HU221294B1 (en) 2002-09-28
IL94983A0 (en) 1991-06-10
IT1241460B (it) 1994-01-17
GB2265311B (en) 1994-02-09
AU641407B2 (en) 1993-09-23
HK197496A (en) 1996-11-08
DE4021517A1 (de) 1991-01-17
NO320444B1 (no) 2005-12-05
SG26416G (en) 1995-09-01
GR1001121B (el) 1993-04-28

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