HU903974D0 - Process for the preparation of products with elongated effect, containing water-soluble peptides - Google Patents

Process for the preparation of products with elongated effect, containing water-soluble peptides

Info

Publication number
HU903974D0
HU903974D0 HU903974A HU397490A HU903974D0 HU 903974 D0 HU903974 D0 HU 903974D0 HU 903974 A HU903974 A HU 903974A HU 397490 A HU397490 A HU 397490A HU 903974 D0 HU903974 D0 HU 903974D0
Authority
HU
Hungary
Prior art keywords
products
preparation
containing water
soluble peptides
elongated effect
Prior art date
Application number
HU903974A
Other languages
Hungarian (hu)
Other versions
HU221294B1 (en
HUT54037A (en
Inventor
David Bodmer
Jones Wing Fong
Thomas Kissel
Hawkins Valliant Maulding
Oskar Nagele
Jane Edna Pearson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to HU9700678A priority Critical patent/HU217117B/en
Publication of HU903974D0 publication Critical patent/HU903974D0/en
Priority to US07/643,880 priority patent/US5538739A/en
Publication of HUT54037A publication Critical patent/HUT54037A/en
Priority to PH41987A priority patent/PH30995A/en
Priority to US08/470,072 priority patent/US5639480A/en
Priority to US08/470,909 priority patent/US5688530A/en
Priority to US08/470,907 priority patent/US5876761A/en
Publication of HU221294B1 publication Critical patent/HU221294B1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU974/90A 1989-07-07 1990-06-25 Process for producing retarde compositions containing the active ingredient in a polymeric carrier HU221294B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
HU9700678A HU217117B (en) 1989-09-22 1990-06-25 Process for producing oktreotide pamoate
US07/643,880 US5538739A (en) 1989-07-07 1991-01-18 Sustained release formulations of water soluble peptides
PH41987A PH30995A (en) 1989-07-07 1991-02-13 Sustained release formulations of water soluble peptides.
US08/470,072 US5639480A (en) 1989-07-07 1995-06-06 Sustained release formulations of water soluble peptides
US08/470,909 US5688530A (en) 1989-07-07 1995-06-06 Sustained release formulations of water soluble peptides
US08/470,907 US5876761A (en) 1989-07-07 1995-06-06 Sustained release formulations of water soluble peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (3)

Publication Number Publication Date
HU903974D0 true HU903974D0 (en) 1990-11-28
HUT54037A HUT54037A (en) 1991-01-28
HU221294B1 HU221294B1 (en) 2002-09-28

Family

ID=27007654

Family Applications (2)

Application Number Title Priority Date Filing Date
HU974/90A HU221294B1 (en) 1989-07-07 1990-06-25 Process for producing retarde compositions containing the active ingredient in a polymeric carrier
HU95P/P00523P HU211602A9 (en) 1989-07-07 1995-06-28 Sustained release formulations of water soluble peptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU95P/P00523P HU211602A9 (en) 1989-07-07 1995-06-28 Sustained release formulations of water soluble peptides

Country Status (27)

Country Link
JP (5) JPH0832624B2 (en)
KR (2) KR100303681B1 (en)
AT (1) AT406225B (en)
AU (2) AU641407B2 (en)
BE (1) BE1004486A3 (en)
CA (1) CA2020477C (en)
CH (1) CH685230A5 (en)
CY (1) CY1965A (en)
DE (2) DE4042752B4 (en)
DK (1) DK175849B1 (en)
FI (3) FI108611B (en)
FR (1) FR2649319A1 (en)
GB (2) GB2234896B (en)
GR (1) GR1001121B (en)
HK (2) HK97695A (en)
HU (2) HU221294B1 (en)
IE (2) IE64216B1 (en)
IL (3) IL131880A (en)
IT (1) IT1241460B (en)
LU (1) LU87764A1 (en)
MY (1) MY106722A (en)
NL (1) NL195027C (en)
NO (2) NO302928B1 (en)
NZ (1) NZ234384A (en)
PT (1) PT94628B (en)
SE (1) SE512992C2 (en)
SG (1) SG26416G (en)

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US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
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AU4198793A (en) 1992-07-24 1994-01-27 Takeda Chemical Industries Ltd. Microparticle preparation and production thereof
JP2944419B2 (en) * 1993-05-10 1999-09-06 ノバルティス アクチエンゲゼルシャフト Stability of pharmacologically active ingredients in sustained release compositions
US5603960A (en) * 1993-05-25 1997-02-18 O'hagan; Derek T. Preparation of microparticles and method of immunization
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US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
DE19545257A1 (en) 1995-11-24 1997-06-19 Schering Ag Process for the production of morphologically uniform microcapsules and microcapsules produced by this process
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6226656B1 (en) 1998-11-12 2001-05-01 Sourcefinder, Inc. System and method for creating, generating and processing user-defined generic specs
US7107268B1 (en) 1998-11-12 2006-09-12 Printable Technologies, Inc. Centralized system and method for managing enterprise operations
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US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
EP1343480B2 (en) 2000-12-21 2016-02-17 Alrise Biosystems GmbH Induced phase transition method for the production of microparticles containing hydrophobic active agents
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
AR044852A1 (en) * 2003-06-24 2005-10-05 Novartis Ag A PHARMACEUTICAL COMPOSITION FOR PARENTERAL ADMINISTRATION THAT INCLUDES A SOMATOSTATINE ANALOG
ES2600554T3 (en) * 2003-07-18 2017-02-09 Oakwood Laboratories L.L.C. Prevention of polymer molecular weight reduction, impurity formation and gelation in polymeric compositions
MY158342A (en) 2003-11-14 2016-09-30 Novartis Ag Pharmaceutical composition
CN1921880A (en) * 2004-02-26 2007-02-28 独立行政法人科学技术振兴机构 Protein drug sustained-release microparticle preparation for injection and process for producing the same
DE102004053373A1 (en) * 2004-11-02 2006-05-04 Justus-Liebig-Universität Giessen Invention relating to nano / meso-fiber anisometric particles in the form of nano / meso-fiber tubes, cables and their curved or branched modifications
KR100741867B1 (en) * 2005-07-05 2007-07-24 전북대학교산학협력단 Preparation method of double-layered sphere using oil-in-water and solvent evaporation
CN103251929A (en) * 2005-12-22 2013-08-21 诺瓦提斯公司 Sustained release formulation comprising octreotide and two or more polylactide-co-glycolide polymers
KR100816065B1 (en) * 2006-11-27 2008-03-24 동국제약 주식회사 Preparation method of sustained-release microcapsules having good initial burst inhibiting property and the microcapsules thereby
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Also Published As

Publication number Publication date
FR2649319A1 (en) 1991-01-11
CY1965A (en) 1997-07-04
ATA144090A (en) 1999-08-15
AU2332195A (en) 1995-09-07
JPH08198771A (en) 1996-08-06
CA2020477C (en) 2000-11-21
GB2265311A (en) 1993-09-29
AU5874690A (en) 1991-01-10
IT1241460B (en) 1994-01-17
FI20000059A (en) 2000-01-12
KR100303681B1 (en) 2002-05-16
GB2234896A (en) 1991-02-20
IL131880A (en) 2001-12-23
NO983923D0 (en) 1998-08-26
PT94628B (en) 1997-06-30
GR900100513A (en) 1991-12-10
IE64411B1 (en) 1995-08-09
SG26416G (en) 1995-09-01
LU87764A1 (en) 1992-03-11
CA2020477A1 (en) 1991-01-08
BE1004486A3 (en) 1992-12-01
CH685230A5 (en) 1995-05-15
NL195027C (en) 2003-12-02
SE9002364D0 (en) 1990-07-05
AT406225B (en) 2000-03-27
IT9048113A0 (en) 1990-07-05
NO320444B1 (en) 2005-12-05
FI20000060A (en) 2000-01-12
DK162590A (en) 1991-01-08
NL9001537A (en) 1991-02-01
SE9002364L (en) 1991-01-08
HU211602A9 (en) 1995-12-28
DK162590D0 (en) 1990-07-05
IT9048113A1 (en) 1992-01-05
NO903001L (en) 1991-01-08
GB9014704D0 (en) 1990-08-22
AU641407B2 (en) 1993-09-23
IL131881A (en) 2001-12-23
DE4021517B4 (en) 2009-04-09
MY106722A (en) 1995-07-31
FI108611B (en) 2002-02-28
FI903429A0 (en) 1990-07-06
DE4042752B4 (en) 2009-05-07
DK175849B1 (en) 2005-03-29
PT94628A (en) 1991-03-20
JPH07285853A (en) 1995-10-31
DE4021517A1 (en) 1991-01-17
HU221294B1 (en) 2002-09-28
KR100442931B1 (en) 2004-08-02
FR2649319B1 (en) 1994-12-09
JPH07309897A (en) 1995-11-28
IE902435A1 (en) 1991-02-13
FI109543B (en) 2002-08-30
HK97695A (en) 1995-06-23
SE512992C2 (en) 2000-06-12
GB2265311B (en) 1994-02-09
NO983923L (en) 1991-01-08
HK197496A (en) 1996-11-08
IL94983A0 (en) 1991-06-10
FI109334B (en) 2002-07-15
JP2931773B2 (en) 1999-08-09
NO903001D0 (en) 1990-07-05
HUT54037A (en) 1991-01-28
JPH0368511A (en) 1991-03-25
KR910002430A (en) 1991-02-25
JP2001233897A (en) 2001-08-28
GB2234896B (en) 1994-01-19
NZ234384A (en) 1994-05-26
IE64216B1 (en) 1995-07-26
JPH0832624B2 (en) 1996-03-29
NO302928B1 (en) 1998-05-11
AU687553B2 (en) 1998-02-26
NL195027B (en) 2003-08-01
GR1001121B (en) 1993-04-28
IL94983A (en) 1999-08-17
GB9306204D0 (en) 1993-05-19

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