HUT54037A - Process for producing retarde compositions containing water-soluble peptides - Google Patents

Process for producing retarde compositions containing water-soluble peptides

Info

Publication number
HUT54037A
HUT54037A HU903974A HU397490A HUT54037A HU T54037 A HUT54037 A HU T54037A HU 903974 A HU903974 A HU 903974A HU 397490 A HU397490 A HU 397490A HU T54037 A HUT54037 A HU T54037A
Authority
HU
Hungary
Prior art keywords
retarde
producing
compositions containing
containing water
soluble peptides
Prior art date
Application number
HU903974A
Other languages
Hungarian (hu)
Other versions
HU221294B1 (en
HU903974D0 (en
Inventor
David Bodmer
Jones Wing Fong
Thomas Kissel
Hawkins Valliant Maulding
Oskar Nagele
Jane Edna Pearson
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to HU9700678A priority Critical patent/HU217117B/en
Publication of HU903974D0 publication Critical patent/HU903974D0/en
Priority to US07/643,880 priority patent/US5538739A/en
Publication of HUT54037A publication Critical patent/HUT54037A/en
Priority to PH41987A priority patent/PH30995A/en
Priority to US08/470,072 priority patent/US5639480A/en
Priority to US08/470,909 priority patent/US5688530A/en
Priority to US08/470,907 priority patent/US5876761A/en
Publication of HU221294B1 publication Critical patent/HU221294B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/23—Calcitonins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/31—Somatostatins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HU974/90A 1989-07-07 1990-06-25 Process for producing retarde compositions containing the active ingredient in a polymeric carrier HU221294B1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
HU9700678A HU217117B (en) 1989-09-22 1990-06-25 Process for producing oktreotide pamoate
US07/643,880 US5538739A (en) 1989-07-07 1991-01-18 Sustained release formulations of water soluble peptides
PH41987A PH30995A (en) 1989-07-07 1991-02-13 Sustained release formulations of water soluble peptides.
US08/470,072 US5639480A (en) 1989-07-07 1995-06-06 Sustained release formulations of water soluble peptides
US08/470,909 US5688530A (en) 1989-07-07 1995-06-06 Sustained release formulations of water soluble peptides
US08/470,907 US5876761A (en) 1989-07-07 1995-06-06 Sustained release formulations of water soluble peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (3)

Publication Number Publication Date
HU903974D0 HU903974D0 (en) 1990-11-28
HUT54037A true HUT54037A (en) 1991-01-28
HU221294B1 HU221294B1 (en) 2002-09-28

Family

ID=27007654

Family Applications (2)

Application Number Title Priority Date Filing Date
HU974/90A HU221294B1 (en) 1989-07-07 1990-06-25 Process for producing retarde compositions containing the active ingredient in a polymeric carrier
HU95P/P00523P HU211602A9 (en) 1989-07-07 1995-06-28 Sustained release formulations of water soluble peptides

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU95P/P00523P HU211602A9 (en) 1989-07-07 1995-06-28 Sustained release formulations of water soluble peptides

Country Status (27)

Country Link
JP (5) JPH0832624B2 (en)
KR (2) KR100303681B1 (en)
AT (1) AT406225B (en)
AU (2) AU641407B2 (en)
BE (1) BE1004486A3 (en)
CA (1) CA2020477C (en)
CH (1) CH685230A5 (en)
CY (1) CY1965A (en)
DE (2) DE4042752B4 (en)
DK (1) DK175849B1 (en)
FI (3) FI108611B (en)
FR (1) FR2649319A1 (en)
GB (2) GB2234896B (en)
GR (1) GR1001121B (en)
HK (2) HK97695A (en)
HU (2) HU221294B1 (en)
IE (2) IE64216B1 (en)
IL (3) IL94983A (en)
IT (1) IT1241460B (en)
LU (1) LU87764A1 (en)
MY (1) MY106722A (en)
NL (1) NL195027C (en)
NO (2) NO302928B1 (en)
NZ (1) NZ234384A (en)
PT (1) PT94628B (en)
SE (1) SE512992C2 (en)
SG (1) SG26416G (en)

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US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
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DE19545257A1 (en) 1995-11-24 1997-06-19 Schering Ag Process for the production of morphologically uniform microcapsules and microcapsules produced by this process
US5817343A (en) * 1996-05-14 1998-10-06 Alkermes, Inc. Method for fabricating polymer-based controlled-release devices
US5968895A (en) * 1996-12-11 1999-10-19 Praecis Pharmaceuticals, Inc. Pharmaceutical formulations for sustained drug delivery
US6126919A (en) 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6632457B1 (en) * 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6226656B1 (en) 1998-11-12 2001-05-01 Sourcefinder, Inc. System and method for creating, generating and processing user-defined generic specs
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US6204308B1 (en) 1999-03-01 2001-03-20 Novartis Ag Organic compounds
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US6824822B2 (en) * 2001-08-31 2004-11-30 Alkermes Controlled Therapeutics Inc. Ii Residual solvent extraction method and microparticles produced thereby
JP2004516262A (en) 2000-12-21 2004-06-03 ネクター セラピューティクス Induced phase transition method for the production of microparticles containing hydrophilic activators
US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
PE20050285A1 (en) * 2003-06-24 2005-06-09 Novartis Ag PHARMACEUTICAL COMPOSITION INCLUDING CYCLIC ANALOGS OF SOMATOSTATIN
JP2008518881A (en) * 2003-07-18 2008-06-05 オークウッド ラボラトリーズ，エル．エル．シー． Prevention of molecular weight reduction, impurity formation and gelation of polymer in polymer composition
MY158342A (en) 2003-11-14 2016-09-30 Novartis Ag Pharmaceutical composition
JPWO2005082405A1 (en) * 2004-02-26 2007-10-25 独立行政法人科学技術振興機構 Sustained release fine particle preparation for protein drug injection and its production method
DE102004053373A1 (en) * 2004-11-02 2006-05-04 Justus-Liebig-Universität Giessen Invention relating to nano / meso-fiber anisometric particles in the form of nano / meso-fiber tubes, cables and their curved or branched modifications
KR100741867B1 (en) * 2005-07-05 2007-07-24 전북대학교산학협력단 Preparation method of double-layered sphere using oil-in-water and solvent evaporation
KR20130024987A (en) * 2005-12-22 2013-03-08 노파르티스 아게 Sustained release formulation comprising octreotide and two or more polylactide-co-glycolide polymers
KR100816065B1 (en) * 2006-11-27 2008-03-24 동국제약 주식회사 Preparation method of sustained-release microcapsules having good initial burst inhibiting property and the microcapsules thereby
CA2713339C (en) 2008-01-30 2017-01-17 Novartis Ag Sustained release formulation comprising octreotide and three linear polylactide-co-glycolide polymers
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
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TW201605488A (en) 2013-10-15 2016-02-16 大塚製藥股份有限公司 Drug for preventing and/or treating polycystic kidney disease
KR102464650B1 (en) 2016-05-03 2022-11-10 엘에스일렉트릭(주) Current limiting device of circuit breaker
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
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Also Published As

Publication number Publication date
AU5874690A (en) 1991-01-10
GB2265311A (en) 1993-09-29
DK175849B1 (en) 2005-03-29
GR900100513A (en) 1991-12-10
NO302928B1 (en) 1998-05-11
FR2649319B1 (en) 1994-12-09
DE4021517B4 (en) 2009-04-09
DK162590D0 (en) 1990-07-05
CA2020477C (en) 2000-11-21
JPH07285853A (en) 1995-10-31
IE64411B1 (en) 1995-08-09
FR2649319A1 (en) 1991-01-11
SE9002364L (en) 1991-01-08
PT94628A (en) 1991-03-20
JPH08198771A (en) 1996-08-06
NO903001D0 (en) 1990-07-05
GB2234896B (en) 1994-01-19
JP2001233897A (en) 2001-08-28
AU687553B2 (en) 1998-02-26
KR100303681B1 (en) 2002-05-16
NL195027B (en) 2003-08-01
IT1241460B (en) 1994-01-17
IL94983A (en) 1999-08-17
CY1965A (en) 1997-07-04
SG26416G (en) 1995-09-01
JP2931773B2 (en) 1999-08-09
HU221294B1 (en) 2002-09-28
ATA144090A (en) 1999-08-15
AT406225B (en) 2000-03-27
JPH07309897A (en) 1995-11-28
GB9014704D0 (en) 1990-08-22
JPH0368511A (en) 1991-03-25
NL195027C (en) 2003-12-02
NO983923D0 (en) 1998-08-26
SE512992C2 (en) 2000-06-12
FI20000059A (en) 2000-01-12
SE9002364D0 (en) 1990-07-05
NO983923L (en) 1991-01-08
CA2020477A1 (en) 1991-01-08
FI109334B (en) 2002-07-15
BE1004486A3 (en) 1992-12-01
IL131880A (en) 2001-12-23
GB2234896A (en) 1991-02-20
KR910002430A (en) 1991-02-25
IT9048113A1 (en) 1992-01-05
DE4042752B4 (en) 2009-05-07
NO320444B1 (en) 2005-12-05
DK162590A (en) 1991-01-08
HK97695A (en) 1995-06-23
AU2332195A (en) 1995-09-07
FI108611B (en) 2002-02-28
NO903001L (en) 1991-01-08
IL94983A0 (en) 1991-06-10
IE902435A1 (en) 1991-02-13
JPH0832624B2 (en) 1996-03-29
HU211602A9 (en) 1995-12-28
NL9001537A (en) 1991-02-01
IE64216B1 (en) 1995-07-26
FI903429A0 (en) 1990-07-06
HU903974D0 (en) 1990-11-28
CH685230A5 (en) 1995-05-15
LU87764A1 (en) 1992-03-11
FI109543B (en) 2002-08-30
PT94628B (en) 1997-06-30
MY106722A (en) 1995-07-31
FI20000060A (en) 2000-01-12
AU641407B2 (en) 1993-09-23
DE4021517A1 (en) 1991-01-17
HK197496A (en) 1996-11-08
IT9048113A0 (en) 1990-07-05
GB9306204D0 (en) 1993-05-19
GB2265311B (en) 1994-02-09
GR1001121B (en) 1993-04-28
IL131881A (en) 2001-12-23
KR100442931B1 (en) 2004-08-02
NZ234384A (en) 1994-05-26

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