HK197496A - Processes for the preparation of sustained release formulations of water soluble peptides - Google Patents

Processes for the preparation of sustained release formulations of water soluble peptides

Info

Publication number
HK197496A
HK197496A HK197496A HK197496A HK197496A HK 197496 A HK197496 A HK 197496A HK 197496 A HK197496 A HK 197496A HK 197496 A HK197496 A HK 197496A HK 197496 A HK197496 A HK 197496A
Authority
HK
Hong Kong
Prior art keywords
processes
preparation
water soluble
sustained release
release formulations
Prior art date
Application number
HK197496A
Other languages
English (en)
Inventor
David Bodmer
Jones Wing Fong
Thomas Kissel
Hawkins Vaillant Maulding
Oskar Nagele
Jane Edna Pearson
Original Assignee
Sandoz Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ltd filed Critical Sandoz Ltd
Publication of HK197496A publication Critical patent/HK197496A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • A61K38/095Oxytocins; Vasopressins; Related peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/23Calcitonins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/31Somatostatins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/02Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK197496A 1989-07-07 1996-10-31 Processes for the preparation of sustained release formulations of water soluble peptides HK197496A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37702389A 1989-07-07 1989-07-07
US41134789A 1989-09-22 1989-09-22

Publications (1)

Publication Number Publication Date
HK197496A true HK197496A (en) 1996-11-08

Family

ID=27007654

Family Applications (2)

Application Number Title Priority Date Filing Date
HK97695A HK97695A (en) 1989-07-07 1995-06-15 Sustained release formulations of water soluble peptides
HK197496A HK197496A (en) 1989-07-07 1996-10-31 Processes for the preparation of sustained release formulations of water soluble peptides

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK97695A HK97695A (en) 1989-07-07 1995-06-15 Sustained release formulations of water soluble peptides

Country Status (27)

Country Link
JP (5) JPH0832624B2 (xx)
KR (2) KR100303681B1 (xx)
AT (1) AT406225B (xx)
AU (2) AU641407B2 (xx)
BE (1) BE1004486A3 (xx)
CA (1) CA2020477C (xx)
CH (1) CH685230A5 (xx)
CY (1) CY1965A (xx)
DE (2) DE4042752B4 (xx)
DK (1) DK175849B1 (xx)
FI (3) FI108611B (xx)
FR (1) FR2649319A1 (xx)
GB (2) GB2234896B (xx)
GR (1) GR1001121B (xx)
HK (2) HK97695A (xx)
HU (2) HU221294B1 (xx)
IE (2) IE64216B1 (xx)
IL (3) IL94983A (xx)
IT (1) IT1241460B (xx)
LU (1) LU87764A1 (xx)
MY (1) MY106722A (xx)
NL (1) NL195027C (xx)
NO (2) NO302928B1 (xx)
NZ (1) NZ234384A (xx)
PT (1) PT94628B (xx)
SE (1) SE512992C2 (xx)
SG (1) SG26416G (xx)

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US20040097419A1 (en) * 2002-11-19 2004-05-20 Holger Petersen Organic compounds
PE20050285A1 (es) * 2003-06-24 2005-06-09 Novartis Ag Composicion farmaceutica que comprende analogos ciclicos de somatostatina
JP2008518881A (ja) * 2003-07-18 2008-06-05 オークウッド ラボラトリーズ,エル.エル.シー. 高分子組成物中の高分子の分子量低下、不純物形成およびゲル化の防止
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DE102004053373A1 (de) * 2004-11-02 2006-05-04 Justus-Liebig-Universität Giessen Erfindung betreffend anisometrische Partikel in Form von Nano-/Meso-Fasern -Röhren, -Kabeln -Bändern und deren gekrümmte oder verzweigte Abwandlungen
KR100741867B1 (ko) * 2005-07-05 2007-07-24 전북대학교산학협력단 수중유적 및 용매 증발법을 이용한 이중층 미립구의제조방법
KR20130024987A (ko) * 2005-12-22 2013-03-08 노파르티스 아게 옥트레오티드 및 2종 이상의 폴리락티드-코-글리콜리드 중합체를 포함하는 서방형 제제
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CA2713339C (en) 2008-01-30 2017-01-17 Novartis Ag Sustained release formulation comprising octreotide and three linear polylactide-co-glycolide polymers
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Also Published As

Publication number Publication date
AU5874690A (en) 1991-01-10
GB2265311A (en) 1993-09-29
DK175849B1 (da) 2005-03-29
GR900100513A (en) 1991-12-10
NO302928B1 (no) 1998-05-11
HUT54037A (en) 1991-01-28
FR2649319B1 (xx) 1994-12-09
DE4021517B4 (de) 2009-04-09
DK162590D0 (da) 1990-07-05
CA2020477C (en) 2000-11-21
JPH07285853A (ja) 1995-10-31
IE64411B1 (en) 1995-08-09
FR2649319A1 (fr) 1991-01-11
SE9002364L (sv) 1991-01-08
PT94628A (pt) 1991-03-20
JPH08198771A (ja) 1996-08-06
NO903001D0 (no) 1990-07-05
GB2234896B (en) 1994-01-19
JP2001233897A (ja) 2001-08-28
AU687553B2 (en) 1998-02-26
KR100303681B1 (ko) 2002-05-16
NL195027B (nl) 2003-08-01
IT1241460B (it) 1994-01-17
IL94983A (en) 1999-08-17
CY1965A (en) 1997-07-04
SG26416G (en) 1995-09-01
JP2931773B2 (ja) 1999-08-09
HU221294B1 (en) 2002-09-28
ATA144090A (de) 1999-08-15
AT406225B (de) 2000-03-27
JPH07309897A (ja) 1995-11-28
GB9014704D0 (en) 1990-08-22
JPH0368511A (ja) 1991-03-25
NL195027C (nl) 2003-12-02
NO983923D0 (no) 1998-08-26
SE512992C2 (sv) 2000-06-12
FI20000059A (fi) 2000-01-12
SE9002364D0 (sv) 1990-07-05
NO983923L (no) 1991-01-08
CA2020477A1 (en) 1991-01-08
FI109334B (fi) 2002-07-15
BE1004486A3 (fr) 1992-12-01
IL131880A (en) 2001-12-23
GB2234896A (en) 1991-02-20
KR910002430A (ko) 1991-02-25
IT9048113A1 (it) 1992-01-05
DE4042752B4 (de) 2009-05-07
NO320444B1 (no) 2005-12-05
DK162590A (da) 1991-01-08
HK97695A (en) 1995-06-23
AU2332195A (en) 1995-09-07
FI108611B (fi) 2002-02-28
NO903001L (no) 1991-01-08
IL94983A0 (en) 1991-06-10
IE902435A1 (en) 1991-02-13
JPH0832624B2 (ja) 1996-03-29
HU211602A9 (en) 1995-12-28
NL9001537A (nl) 1991-02-01
IE64216B1 (en) 1995-07-26
FI903429A0 (fi) 1990-07-06
HU903974D0 (en) 1990-11-28
CH685230A5 (de) 1995-05-15
LU87764A1 (fr) 1992-03-11
FI109543B (fi) 2002-08-30
PT94628B (pt) 1997-06-30
MY106722A (en) 1995-07-31
FI20000060A (fi) 2000-01-12
AU641407B2 (en) 1993-09-23
DE4021517A1 (de) 1991-01-17
IT9048113A0 (it) 1990-07-05
GB9306204D0 (en) 1993-05-19
GB2265311B (en) 1994-02-09
GR1001121B (el) 1993-04-28
IL131881A (en) 2001-12-23
KR100442931B1 (ko) 2004-08-02
NZ234384A (en) 1994-05-26

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