AU641407B2 - Octreotide-pamoate - Google Patents
Octreotide-pamoate Download PDFInfo
- Publication number
- AU641407B2 AU641407B2 AU58746/90A AU5874690A AU641407B2 AU 641407 B2 AU641407 B2 AU 641407B2 AU 58746/90 A AU58746/90 A AU 58746/90A AU 5874690 A AU5874690 A AU 5874690A AU 641407 B2 AU641407 B2 AU 641407B2
- Authority
- AU
- Australia
- Prior art keywords
- octreotide
- pamoate
- preparation
- acid
- spe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/095—Oxytocins; Vasopressins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/23—Calcitonins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37702389A | 1989-07-07 | 1989-07-07 | |
US377023 | 1989-07-07 | ||
US41134789A | 1989-09-22 | 1989-09-22 | |
US411347 | 1989-09-22 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU41986/93A Division AU663388B2 (en) | 1989-07-07 | 1993-07-15 | Sustained release formulations |
AU41985/93A Division AU662825B2 (en) | 1989-07-07 | 1993-07-15 | Process for the production of microparticles |
Publications (2)
Publication Number | Publication Date |
---|---|
AU5874690A AU5874690A (en) | 1991-01-10 |
AU641407B2 true AU641407B2 (en) | 1993-09-23 |
Family
ID=27007654
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU58746/90A Expired AU641407B2 (en) | 1989-07-07 | 1990-07-05 | Octreotide-pamoate |
AU23321/95A Expired AU687553B2 (en) | 1989-07-07 | 1995-06-29 | Process for the production of microparticles |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU23321/95A Expired AU687553B2 (en) | 1989-07-07 | 1995-06-29 | Process for the production of microparticles |
Country Status (27)
Country | Link |
---|---|
JP (5) | JPH0832624B2 (he) |
KR (2) | KR100303681B1 (he) |
AT (1) | AT406225B (he) |
AU (2) | AU641407B2 (he) |
BE (1) | BE1004486A3 (he) |
CA (1) | CA2020477C (he) |
CH (1) | CH685230A5 (he) |
CY (1) | CY1965A (he) |
DE (2) | DE4042752B4 (he) |
DK (1) | DK175849B1 (he) |
FI (3) | FI108611B (he) |
FR (1) | FR2649319A1 (he) |
GB (2) | GB2234896B (he) |
GR (1) | GR1001121B (he) |
HK (2) | HK97695A (he) |
HU (2) | HU221294B1 (he) |
IE (2) | IE64411B1 (he) |
IL (3) | IL131880A (he) |
IT (1) | IT1241460B (he) |
LU (1) | LU87764A1 (he) |
MY (1) | MY106722A (he) |
NL (1) | NL195027C (he) |
NO (2) | NO302928B1 (he) |
NZ (1) | NZ234384A (he) |
PT (1) | PT94628B (he) |
SE (1) | SE512992C2 (he) |
SG (1) | SG26416G (he) |
Families Citing this family (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4990336A (en) * | 1989-02-08 | 1991-02-05 | Biosearch, Inc. | Sustained release dosage form |
YU48420B (sh) * | 1991-03-25 | 1998-07-10 | Hoechst Aktiengesellschaft | Postupak za dobijanje biološki razgradljivih mikročestica sa dugotrajnim delovanjem |
CH683149A5 (fr) * | 1991-07-22 | 1994-01-31 | Debio Rech Pharma Sa | Procédé pour la préparation de microsphères en matériau polymère biodégradable. |
US5876452A (en) * | 1992-02-14 | 1999-03-02 | Board Of Regents, University Of Texas System | Biodegradable implant |
US6013853A (en) * | 1992-02-14 | 2000-01-11 | The University Of Texas System | Continuous release polymeric implant carrier |
DE4218510A1 (de) * | 1992-06-02 | 1993-12-09 | Pharmatech Gmbh | Verfahren zur Herstellung biologisch abbaubarer Polyester |
AU4198793A (en) † | 1992-07-24 | 1994-01-27 | Takeda Chemical Industries Ltd. | Microparticle preparation and production thereof |
CA2123144A1 (en) * | 1993-05-10 | 1994-11-11 | David Bodmer | Stabilisation of pharmacologically active compounds in sustained release compositions |
GB9310781D0 (en) * | 1993-05-25 | 1993-07-14 | Davis Stanley S | Preparation of microparticles |
US5603960A (en) * | 1993-05-25 | 1997-02-18 | O'hagan; Derek T. | Preparation of microparticles and method of immunization |
JP3645906B2 (ja) | 1993-11-19 | 2005-05-11 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | マイクロカプセル封入された3−ピペリジニル−置換1,2−ベンズイソオキサゾール類及び1,2−ベンズイソチアゾール類 |
US6270795B1 (en) | 1995-11-09 | 2001-08-07 | Microbiological Research Authority | Method of making microencapsulated DNA for vaccination and gene therapy |
ATE192334T1 (de) | 1995-11-09 | 2000-05-15 | Microbiological Res Authority | Mikroverkapselte dna zur impfung und gentherapie |
DE19545257A1 (de) | 1995-11-24 | 1997-06-19 | Schering Ag | Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln |
US5817343A (en) * | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
US5968895A (en) * | 1996-12-11 | 1999-10-19 | Praecis Pharmaceuticals, Inc. | Pharmaceutical formulations for sustained drug delivery |
US6126919A (en) | 1997-02-07 | 2000-10-03 | 3M Innovative Properties Company | Biocompatible compounds for pharmaceutical drug delivery systems |
GB9810236D0 (en) | 1998-05-13 | 1998-07-08 | Microbiological Res Authority | Improvements relating to encapsulation of bioactive agents |
US6632457B1 (en) * | 1998-08-14 | 2003-10-14 | Incept Llc | Composite hydrogel drug delivery systems |
US6226656B1 (en) | 1998-11-12 | 2001-05-01 | Sourcefinder, Inc. | System and method for creating, generating and processing user-defined generic specs |
US7107268B1 (en) | 1998-11-12 | 2006-09-12 | Printable Technologies, Inc. | Centralized system and method for managing enterprise operations |
US6204308B1 (en) | 1999-03-01 | 2001-03-20 | Novartis Ag | Organic compounds |
EP1044683A1 (en) * | 1999-04-15 | 2000-10-18 | Debio Recherche Pharmaceutique S.A. | One-step dispersion method for the microencapsulation of water soluble substances |
US6461631B1 (en) * | 1999-11-16 | 2002-10-08 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
KR100392501B1 (ko) * | 2000-06-28 | 2003-07-22 | 동국제약 주식회사 | 다중 에멀젼법에 의한 서방출성 미립구의 제조방법 |
US6824822B2 (en) * | 2001-08-31 | 2004-11-30 | Alkermes Controlled Therapeutics Inc. Ii | Residual solvent extraction method and microparticles produced thereby |
WO2002049620A2 (en) | 2000-12-21 | 2002-06-27 | Inhale Therapeutic Systems, Inc. | Induced phase transition method for the production of microparticles containing hydrophobic active agents |
US20040097419A1 (en) * | 2002-11-19 | 2004-05-20 | Holger Petersen | Organic compounds |
AR044852A1 (es) * | 2003-06-24 | 2005-10-05 | Novartis Ag | Una composicion farmaceutica para la administracion parenteral que comprende un analogo de somatostatina |
EP1660039B1 (en) * | 2003-07-18 | 2016-09-28 | Oakwood Laboratories L.L.C. | Prevention of molecular weight reduction of the polymer, impurity formation and gelling in polymer compositions |
MY158342A (en) | 2003-11-14 | 2016-09-30 | Novartis Ag | Pharmaceutical composition |
CA2557397A1 (en) * | 2004-02-26 | 2005-09-09 | Japan Science And Technology Agency | Protein drug sustained-release microparticle preparation for injection and process for producing the same |
DE102004053373A1 (de) * | 2004-11-02 | 2006-05-04 | Justus-Liebig-Universität Giessen | Erfindung betreffend anisometrische Partikel in Form von Nano-/Meso-Fasern -Röhren, -Kabeln -Bändern und deren gekrümmte oder verzweigte Abwandlungen |
KR100741867B1 (ko) * | 2005-07-05 | 2007-07-24 | 전북대학교산학협력단 | 수중유적 및 용매 증발법을 이용한 이중층 미립구의제조방법 |
BR122019027412B8 (pt) * | 2005-12-22 | 2021-07-27 | Novartis Ag | composição farmacêutica de liberação sustentada na forma de micropartículas, processo para preparação das ditas micropartículas, e kit de administração |
KR100816065B1 (ko) | 2006-11-27 | 2008-03-24 | 동국제약 주식회사 | 초기 방출억제 특성이 우수한 서방출성 마이크로캡슐의제조방법 및 이에 의해 제조되는 마이크로캡슐 |
PL2247282T3 (pl) | 2008-01-30 | 2015-03-31 | Novartis Ag | Preparat o przedłużonym uwalnianiu zawierający oktreotyd oraz trzy liniowe kopolimery poli(laktyd-co-glikolid) |
USRE49251E1 (en) | 2010-01-04 | 2022-10-18 | Mapi Pharma Ltd. | Depot systems comprising glatiramer or pharmacologically acceptable salt thereof |
CA2813301A1 (en) * | 2010-09-30 | 2012-04-05 | Evonik Corporation | Method for removing residual organic solvent from microparticles |
AU2011308897B2 (en) * | 2010-09-30 | 2015-06-18 | Evonik Corporation | Emulsion method for preparing low residual solvent microparticles |
TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及/或治療多囊腎病之藥物 |
KR102464650B1 (ko) | 2016-05-03 | 2022-11-10 | 엘에스일렉트릭(주) | 배선용 차단기의 한류장치 |
US12097292B2 (en) | 2016-08-28 | 2024-09-24 | Mapi Pharma Ltd. | Process for preparing microparticles containing glatiramer acetate |
CA3050086A1 (en) | 2017-03-26 | 2018-10-04 | Mapi Pharma Ltd. | Glatiramer depot systems for treating progressive forms of multiple sclerosis |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
CH644768A5 (de) * | 1977-08-25 | 1984-08-31 | Sandoz Ag | Verfahren zur herstellung von mikrokugeln. |
US4622244A (en) * | 1979-09-04 | 1986-11-11 | The Washington University | Process for preparation of microcapsules |
US4293539A (en) * | 1979-09-12 | 1981-10-06 | Eli Lilly And Company | Controlled release formulations and method of treatment |
ATE2512T1 (de) * | 1979-11-27 | 1983-03-15 | Sandoz Ag | Polypeptide, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen, die diese polypeptide enthalten, und ihre verwendung. |
US4389330A (en) * | 1980-10-06 | 1983-06-21 | Stolle Research And Development Corporation | Microencapsulation process |
PH19942A (en) * | 1980-11-18 | 1986-08-14 | Sintex Inc | Microencapsulation of water soluble polypeptides |
US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
IE52535B1 (en) * | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
EP0092918B1 (en) * | 1982-04-22 | 1988-10-19 | Imperial Chemical Industries Plc | Continuous release formulations |
CH656884A5 (de) * | 1983-08-26 | 1986-07-31 | Sandoz Ag | Polyolester, deren herstellung und verwendung. |
US4485101A (en) * | 1983-10-11 | 1984-11-27 | Administrators Of The Tulane Educational Fund | Peptides |
JPH0657658B2 (ja) * | 1985-04-11 | 1994-08-03 | 住友製薬株式会社 | 徐放性製剤 |
JPS60100516A (ja) * | 1983-11-04 | 1985-06-04 | Takeda Chem Ind Ltd | 徐放型マイクロカプセルの製造法 |
GB8331158D0 (en) * | 1983-11-22 | 1983-12-29 | British Telecomm | Metal/semiconductor deposition |
JPS60181029A (ja) * | 1984-02-29 | 1985-09-14 | Toyo Jozo Co Ltd | 徐放性製剤の製法 |
CH660302A5 (fr) * | 1984-10-17 | 1987-04-15 | Debiopharm Sa | Procede de micro-encapsulation en phase heterogene de substances medicamenteuses hydrosolubles. |
ATE61935T1 (de) * | 1985-02-07 | 1991-04-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung von mikrokapseln. |
US4725577A (en) * | 1985-04-25 | 1988-02-16 | Administrators Of The Tulane Educational Fund | Biologically active lysine containing octapeptides |
CH665558A5 (en) * | 1985-10-09 | 1988-05-31 | Debiopharm Sa | Phase sepn. prodn. of microcapsules for water soluble pharmaceuticals - using fluoro-substd. aliphatic hydrocarbon as non-solvent in the hardening stage |
JP2539789B2 (ja) * | 1986-03-06 | 1996-10-02 | 日本原子力研究所 | ポリラクトンからなる徐放性薬物複合体の製造方法 |
GB2193891B (en) * | 1986-08-18 | 1990-07-25 | Sandoz Ltd | Nasal pharmaceutical composition containing a somatostatin anologue. |
JPH0725689B2 (ja) * | 1986-10-07 | 1995-03-22 | 中外製薬株式会社 | 顆粒球コロニ−刺激因子を含有する徐放性製剤 |
GB2209937B (en) * | 1987-09-21 | 1991-07-03 | Depiopharm S A | Water insoluble polypeptides |
CH672887A5 (he) * | 1987-10-14 | 1990-01-15 | Debiopharm Sa | |
DE3738228A1 (de) * | 1987-11-11 | 1989-05-24 | Hoechst Ag | Verfahren zur herstellung von bioabbaubaren mikrokapseln wasserloeslicher peptide und proteine sowie nach diesem verfahren erhaltene mikrokapseln |
JP2653255B2 (ja) * | 1990-02-13 | 1997-09-17 | 武田薬品工業株式会社 | 長期徐放型マイクロカプセル |
-
1990
- 1990-06-25 HU HU974/90A patent/HU221294B1/hu unknown
- 1990-07-03 GB GB9014704A patent/GB2234896B/en not_active Expired - Lifetime
- 1990-07-03 SG SG1995907374A patent/SG26416G/en unknown
- 1990-07-05 FR FR9008718A patent/FR2649319A1/fr active Granted
- 1990-07-05 BE BE9000693A patent/BE1004486A3/fr not_active IP Right Cessation
- 1990-07-05 IL IL13188090A patent/IL131880A/he active IP Right Grant
- 1990-07-05 IE IE43894A patent/IE64411B1/en not_active IP Right Cessation
- 1990-07-05 SE SE9002364A patent/SE512992C2/sv not_active IP Right Cessation
- 1990-07-05 NL NL9001537A patent/NL195027C/nl not_active IP Right Cessation
- 1990-07-05 IL IL9498390A patent/IL94983A/he active IP Right Grant
- 1990-07-05 CA CA002020477A patent/CA2020477C/en not_active Expired - Lifetime
- 1990-07-05 GR GR900100513A patent/GR1001121B/el not_active IP Right Cessation
- 1990-07-05 DK DK199001625A patent/DK175849B1/da not_active IP Right Cessation
- 1990-07-05 CH CH2249/90A patent/CH685230A5/de not_active IP Right Cessation
- 1990-07-05 IT IT48113A patent/IT1241460B/it active IP Right Grant
- 1990-07-05 IL IL13188190A patent/IL131881A/he active IP Right Grant
- 1990-07-05 NZ NZ234384A patent/NZ234384A/xx unknown
- 1990-07-05 AU AU58746/90A patent/AU641407B2/en not_active Expired
- 1990-07-05 IE IE243590A patent/IE64216B1/en not_active IP Right Cessation
- 1990-07-05 NO NO903001A patent/NO302928B1/no not_active IP Right Cessation
- 1990-07-06 DE DE4042752A patent/DE4042752B4/de not_active Expired - Lifetime
- 1990-07-06 PT PT94628A patent/PT94628B/pt not_active IP Right Cessation
- 1990-07-06 DE DE4021517A patent/DE4021517B4/de not_active Expired - Lifetime
- 1990-07-06 KR KR1019900010224A patent/KR100303681B1/ko not_active IP Right Cessation
- 1990-07-06 FI FI903429A patent/FI108611B/fi active IP Right Grant
- 1990-07-06 AT AT0144090A patent/AT406225B/de not_active IP Right Cessation
- 1990-07-06 JP JP2177665A patent/JPH0832624B2/ja not_active Expired - Lifetime
- 1990-07-06 MY MYPI90001133A patent/MY106722A/en unknown
- 1990-07-09 LU LU87764A patent/LU87764A1/fr unknown
-
1993
- 1993-03-25 GB GB9306204A patent/GB2265311B/en not_active Expired - Lifetime
-
1995
- 1995-04-18 JP JP7116539A patent/JPH07309897A/ja active Pending
- 1995-04-18 JP JP7116486A patent/JP2931773B2/ja not_active Expired - Lifetime
- 1995-06-15 HK HK97695A patent/HK97695A/xx not_active IP Right Cessation
- 1995-06-28 HU HU95P/P00523P patent/HU211602A9/hu unknown
- 1995-06-29 AU AU23321/95A patent/AU687553B2/en not_active Expired
- 1995-08-15 JP JP7228646A patent/JPH08198771A/ja active Pending
-
1996
- 1996-10-31 HK HK197496A patent/HK197496A/xx not_active IP Right Cessation
-
1997
- 1997-07-04 CY CY196597A patent/CY1965A/xx unknown
-
1998
- 1998-08-26 NO NO19983923A patent/NO320444B1/no unknown
-
1999
- 1999-09-14 KR KR1019990039209A patent/KR100442931B1/ko not_active IP Right Cessation
-
2000
- 2000-01-12 FI FI20000060A patent/FI109334B/fi active
- 2000-01-12 FI FI20000059A patent/FI109543B/fi active
-
2001
- 2001-01-15 JP JP2001006486A patent/JP2001233897A/ja active Pending
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