PT3562486T - Uso de dexmedetomidina sublingual para o tratamento da agitação - Google Patents

Uso de dexmedetomidina sublingual para o tratamento da agitação

Info

Publication number
PT3562486T
PT3562486T PT178857504T PT17885750T PT3562486T PT 3562486 T PT3562486 T PT 3562486T PT 178857504 T PT178857504 T PT 178857504T PT 17885750 T PT17885750 T PT 17885750T PT 3562486 T PT3562486 T PT 3562486T
Authority
PT
Portugal
Prior art keywords
agitation
treatment
sublingual dexmedetomidine
dexmedetomidine
sublingual
Prior art date
Application number
PT178857504T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Bioxcel Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioxcel Therapeutics Inc filed Critical Bioxcel Therapeutics Inc
Publication of PT3562486T publication Critical patent/PT3562486T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/4174Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PT178857504T 2016-12-31 2017-12-29 Uso de dexmedetomidina sublingual para o tratamento da agitação PT3562486T (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662441164P 2016-12-31 2016-12-31
US201762471393P 2017-03-15 2017-03-15
US201762542323P 2017-08-08 2017-08-08

Publications (1)

Publication Number Publication Date
PT3562486T true PT3562486T (pt) 2024-06-12

Family

ID=62710955

Family Applications (1)

Application Number Title Priority Date Filing Date
PT178857504T PT3562486T (pt) 2016-12-31 2017-12-29 Uso de dexmedetomidina sublingual para o tratamento da agitação

Country Status (20)

Country Link
US (7) US11839604B2 (enExample)
EP (3) EP4368169A3 (enExample)
JP (5) JP6868698B2 (enExample)
KR (2) KR102793584B1 (enExample)
CN (1) CN110337290A (enExample)
AU (3) AU2017388759B2 (enExample)
BR (1) BR112019013503A2 (enExample)
CA (1) CA3045043A1 (enExample)
DK (1) DK3562486T3 (enExample)
ES (1) ES2980126T3 (enExample)
FI (1) FI3562486T3 (enExample)
HU (1) HUE067266T2 (enExample)
IL (1) IL267689B2 (enExample)
MX (3) MX2019007923A (enExample)
PL (1) PL3562486T3 (enExample)
PT (1) PT3562486T (enExample)
SG (1) SG10202107367SA (enExample)
TW (3) TW202423422A (enExample)
WO (1) WO2018126182A1 (enExample)
ZA (1) ZA202006636B (enExample)

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SG10202107367SA (en) 2016-12-31 2021-08-30 Bioxcel Therapeutics Inc Use of sublingual dexmedetomidine for the treatment of agitation
BR112020026672A2 (pt) 2018-06-27 2021-03-30 Bioxcel Therapeutics, Inc. Formulações de filme contendo dexmedetomidina e métodos para produzi-las
EP3813828A4 (en) * 2018-06-27 2022-03-30 Bioxcel Therapeutics, Inc. METHOD OF TREATMENT OF AGITATION WITH DEXMEDETOMIDIN HYDROCHLORIDE
RU2692247C1 (ru) * 2018-12-06 2019-06-24 федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр имени В.А. Алмазова" Министерства здравоохранения Российской Федерации Способ лечения послеоперационного делирия
CA3145388A1 (en) * 2019-07-19 2021-01-28 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
CA3154659A1 (en) * 2019-09-18 2021-03-25 Bioxcel Therapeutics, Inc. Systems and methods for detection and prevention of emergence of agitation
CN115397414A (zh) * 2020-02-07 2022-11-25 株式会社纽若梵提 包含利美尼定的用于治疗脆性x染色体综合征的组合物
EP4104062A4 (en) * 2020-02-14 2024-04-24 Bioxcel Therapeutics, Inc. SYSTEMS AND METHODS FOR DETECTING AND PREVENTING THE APPEARANCE OF AGITATION
MX2023003993A (es) * 2020-10-08 2023-05-24 Bioxcel Therapeutics Inc Tratamiento de trastornos bipolares y psicosis con clorhidrato de dexmedetomidina.
MX2023007998A (es) * 2021-01-04 2023-08-08 Bioxcel Therapeutics Inc Regimenes de tratamiento con dexmedetomidina.
EP4297871A4 (en) * 2021-02-26 2025-01-01 BioXcel Therapeutics, Inc. METHODS AND COMPOSITIONS FOR TREATING AGITATION
US20240165083A1 (en) 2021-03-19 2024-05-23 Orion Corporation Tasipimidine formulations and use thereof
TW202317101A (zh) * 2021-07-02 2023-05-01 美商百歐克斯賽爾治療公司 治療抑鬱狀態之方法
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WO2024055042A1 (en) * 2022-09-11 2024-03-14 Bioxcel Therapeutics, Inc. Methods for treating agitation in community settings
EP4642453A1 (en) * 2022-12-27 2025-11-05 Alceptor Therapeutics, Inc. (s)-(3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl)methanol for treatment of agitation
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
WO2024263973A1 (en) * 2023-06-23 2024-12-26 Bioxcel Therapeutics, Inc. Dexmedetomidine treatment regimens
CN119139275B (zh) * 2024-11-05 2025-08-22 中国人民解放军军事科学院军事医学研究院 一种盐酸右美托咪定口溶膜及其制备方法和其应用

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JP2022040229A (ja) 2022-03-10
ES2980126T3 (es) 2024-09-30
WO2018126182A1 (en) 2018-07-05
US20250325521A1 (en) 2025-10-23
JP2020503323A (ja) 2020-01-30
AU2022200892B2 (en) 2024-06-13
IL267689A (en) 2019-08-29
US20220031663A1 (en) 2022-02-03
JP2021102654A (ja) 2021-07-15
DK3562486T3 (da) 2024-06-10
KR102793584B1 (ko) 2025-04-09
IL267689B1 (en) 2025-01-01
US20240252470A1 (en) 2024-08-01
AU2024219731A1 (en) 2024-10-10
EP3562486A4 (en) 2020-08-19
ZA202006636B (en) 2023-03-29
TW202319048A (zh) 2023-05-16
EP4371554A3 (en) 2024-08-07
SG10202107367SA (en) 2021-08-30
CN110337290A (zh) 2019-10-15
KR20240031326A (ko) 2024-03-07
US11786508B2 (en) 2023-10-17
PL3562486T3 (pl) 2024-09-16
MX2023000213A (es) 2023-02-09
JP6868698B2 (ja) 2021-05-12
MX2022010274A (es) 2022-09-19
MX2019007923A (es) 2019-09-10
US20230081503A1 (en) 2023-03-16
EP4368169A2 (en) 2024-05-15
AU2017388759A1 (en) 2019-06-13
KR20190108104A (ko) 2019-09-23
EP3562486B1 (en) 2024-03-13
US20190365715A1 (en) 2019-12-05
JP6929479B2 (ja) 2021-09-01
AU2017388759B2 (en) 2021-11-11
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US11839604B2 (en) 2023-12-12
US11931340B2 (en) 2024-03-19

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